Multidrug-Resistant Microorganisms’ (MDROs) Genomic Characteristics Integrated with Serum Biomarkers Measurement in the Diagnosis and Prognosis of Severe Infectious Disease as Sepsis

Dear Colleagues, 

Antimicrobial resistance (AMR) is a global health threat, with multidrug-resistant microorganisms (MDROs) limiting therapeutic options and increasing patient morbidity and mortality. The rapid identification of resistant strains and diagnosis of infections are crucial for patient prognosis and infection control in healthcare settings.

Common adverse events in hospitalized patients include adverse drug events, healthcare-associated infections (HAIs), and surgical complications. Despite advances in preoperative care and surgical techniques, patient comorbidities and surgical factors often lead to postoperative complications (infection, dehiscence, seroma, hematoma, skin and fat necrosis, skin and facial dehiscence or blistering). In particular, an infection of the surgical site or the systemic dissemination of pathogens increases patients’ morbidity and mortality. Active surveillance cultures (ASC) to detect MDRO colonization are essential for infection prevention.

This Special Issue will cover a wide range of topics focusing on antimicrobial resistance (AMR) and multidrug-resistant microorganisms (MDROs): healthcare-associated infections (HCAIs), rapid identification of resistant strains, effective infection control, and using biomarkers like procalcitonin (PCT) and mid-regional-pro-adrenomedullin (MR-proADM) to monitor host responses to pathogens and antibiotic treatments. All types of articles will be considered for publication, including short reports, primary research articles, and reviews.

Dr. Silvia Spoto
Prof. Dr. Silvia Angeletti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.