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Pathogens
Special Issues
Hospital-Acquired Infections: Risk Factors and Preventions—2nd Edition
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Hospital-Acquired Infections: Risk Factors and Preventions—2nd Edition

A special issue of Pathogens (ISSN 2076-0817).

Deadline for manuscript submissions: 31 January 2026 | Viewed by 931

Special Issue Editors

Dr. Gabriele Messina

E-Mail Website
Guest Editor
Department of Molecular and Developmental Medicine, Università degli Studi di Siena, Siena, Italy
Interests: technology; prevention; disinfection; UV radiation; LED; environmental hygiene; high touch; cross-contamination; stethoscopes; HAI
Special Issues, Collections and Topics in MDPI journals
Dr. Davide Amodeo

E-Mail Website
Guest Editor
Department of Medical Biothecnologies, Università degli Studi di Siena, Siena, Italy
Interests: microbiology; environmental hygiene; disinfection; UV radiation; multidrug-resistant bacteria; HAI
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues, 

Nosocomial infections, also known as hospital-acquired infections (HAIs), a term coined in the 1990s, have a significant public health impact in terms of morbidity, mortality, and care-related costs, despite continued advances in the areas of epidemiology and scientific research.

Risk factors and preventive actions compete for the challenge, considering that more than half of HAIs are preventable, especially those associated with certain behaviours, through a multidisciplinary approach.

Interventions are needed at several levels to contain and avoid HAIs: education, adherence to good hygiene practices during care, hand hygiene, patient screening, surveillance, antibiotic stewardship, and guidelines.

Furthermore, an essential element is the environment, where microbes persist and 'high touch' surfaces because of their role in cross-contamination. A holistic approach is the effective key to managing the problem.

The aim of this Special Issue is to bring together technological, structural, educational, and operational experiences for the prevention and management of HAIs.

Dr. Gabriele Messina
Dr. Davide Amodeo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • surgical site infection
  • dialysis infection
  • burn infection
  • bacterial infections
  • Legionella
  • Clostridium difficile
  • ventilator-associated pneumonia prevention
  • female urinary catheter in urinary tract infection prevention
  • endoscope sterilisation and disinfection

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Related Special Issue

Published Papers (1 paper)

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10 pages, 4087 KiB  
Case Report
Tricuspid Valve Infective Endocarditis in a Chronic Haemodialysis Patient with a Hickman Catheter: A Case Report
by Dalila Šačić, Saddam Shawamri, Ivana Jovanović, Marija Boričić-Kostić, Boris Jegorović, Miloš Mijalković, Kristina Filić, Stefan Juričić, Vidna Karadžić-Ristanović, Danka Bjelić, Selena Gajić and Marko Baralić
Pathogens 2025, 14(6), 539; https://doi.org/10.3390/pathogens14060539 - 28 May 2025
Viewed by 500
Abstract
Infective endocarditis (IE) of the tricuspid and pulmonary valve accounts for 5 to 10% of all IE cases and, compared with left-sided IE, is often associated with intravenous (i.v.) drug use, presence of intracardiac devices, and central venous catheters (CVCs), including permanent—Hickman catheter [...] Read more.
Infective endocarditis (IE) of the tricuspid and pulmonary valve accounts for 5 to 10% of all IE cases and, compared with left-sided IE, is often associated with intravenous (i.v.) drug use, presence of intracardiac devices, and central venous catheters (CVCs), including permanent—Hickman catheter (HC). We report a case of a 71-year-old female patient on a chronic hemodialysis (HD) program who had developed IE. Her first symptoms were fever and malaise. Transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE) examinations were performed, revealing vegetations on the tip of HC and the anterior and posterior leaflets of the tricuspid valve (TV). Three blood culture bottles were positive for Enterococcus spp. The HC was replaced with a new CVC to continue HD. After a six-week antibiotic treatment, most clinical symptoms were resolved, and there was a decrease in vegetation size with normalization of inflammatory markers and negative follow-up blood cultures. After this initial improvement in the patient’s condition, the clinical course was complicated by the development of Citrobacter koseri bacteremia and sepsis. Despite adequate antibiotic therapy, the condition progressed to septic shock, which was soon followed by a fatal outcome. IE treatment in HD patients requires long-term broad-spectrum antibiotic therapy, and also, in patients without arteriovenous fistula (AVF), the CVC should be replaced after each HD during IE and sepsis treatment to minimize the patient’s exposure to a foreign body that is susceptible to bacterial colonization. A colonized foreign body is a focus for sustained and spreading infection, and its presence prevents adequate antibiotic treatment until the focus of infection is removed. Full article
(This article belongs to the Special Issue Hospital-Acquired Infections: Risk Factors and Preventions—2nd Edition)
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