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Pathogens
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Emerging Technologies and Approaches for the Prevention and Treatment of...
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Emerging Technologies and Approaches for the Prevention and Treatment of Zoonotic Diseases

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Vaccines and Therapeutic Developments".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 1032

Special Issue Editors

Dr. Alejandra Capozzo

E-Mail Website
Guest Editor
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET Universidad Abierta Interamericana), Centro de Altos Estudios en Ciencias Humanas y de la Salud, Buenos Aires, Argentina
Interests: one health; applied veterinary immunology; foot and mouth disease
Special Issues, Collections and Topics in MDPI journals
Dr. Jesús Hernández

E-Mail Website
Guest Editor
Centro de Investigacion en Alimentacion y Desarrollo, Sonora, Mexico
Interests: immune response; disease control; swine diseases; diagnostic tools; zoonotic diseases; one health; vaccines; adjuvants
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Zoonotic diseases continue to pose significant risks to global health, emphasizing the need for coordinated efforts across human, animal, and environmental sectors. This Special Issue invites original research and reviews on novel technologies for the prevention and treatment of zoonotic diseases, with a focus on integrated One Health strategies.

We welcome contributions on recent advances in vaccine development—mRNA, viral vector, nanoparticle-based, and thermostable platforms—as well as immunotherapeutic approaches, such as monoclonal antibodies and cytokine-based interventions. Studies addressing biotherapeutics, such as bacteriophages, endolysins, and microbiome-derived products, are also encouraged. Submissions that bridge veterinary and human medicine are particularly relevant, especially those providing insights into cross-species prevention and control of infectious diseases.

This Special Issue aims to contribute to the global scientific effort to develop effective, innovative, and sustainable solutions for zoonotic disease management.

Dr. Alejandra Capozzo
Dr. Jesús Hernández
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • one health
  • zoonotic diseases
  • vaccines
  • immunotherapy and biotherapeutics
  • cross-species disease prevention

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Published Papers (1 paper)

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Research

11 pages, 1510 KB  
Article
Unravelling Anopheles Dynamics in a Malaria-Free Paraguay: Species Distributions, Bioclimatic Niches, and Implications for Resurgence Risks
by Florencia del Puerto, Mauricio Grissetti, Luis Ferreira, Luciano Franco and Leidi Herrera
Pathogens 2025, 14(9), 849; https://doi.org/10.3390/pathogens14090849 - 26 Aug 2025
Viewed by 858
Abstract
Malaria, caused by a protozoan parasite of the genus Plasmodium and transmitted by mosquitoes of the genus Anopheles, remains a significant vector-borne disease worldwide. In 2018, Paraguay became the first country in the Americas in 45 years to be certified malaria-free by [...] Read more.
Malaria, caused by a protozoan parasite of the genus Plasmodium and transmitted by mosquitoes of the genus Anopheles, remains a significant vector-borne disease worldwide. In 2018, Paraguay became the first country in the Americas in 45 years to be certified malaria-free by the World Health Organization. Between 2016 and 2017, a period with no reported human malaria cases, the presence of Plasmodium spp. in Anopheles mosquitoes was investigated in the departments of Caaguazú and Alto Paraná. These studies found that the most prevalent Anopheles species in Paraguay, including Anopheles albitarsis (59.4%), Anopheles strodei (21.5%), and other Anopheles species in smaller proportions, were all negative to the parasite. The objective of this study was to re-evaluate these presence data and to define environmentally suitable areas for Anopheles spp. and their association with bioclimatic variables using DIVA-GIS/MaxEnt software for the entomological surveillance of malaria risk in Paraguay. Results showed that areas of bioclimatic suitability included the Humid Chaco, Cerrado, Paraná Atlantic Forest, and Southern Cone Mesopotamian savanna ecoregions. The most relevant climatic variables were the precipitation of the wettest month (contribution of 80.4%) and the precipitation of the driest month (contribution of 18.4%). Anopheles albitarsis, also reported as a vector of the Venezuelan equine encephalitis virus in neighbouring countries, was the most abundant mosquito species. Anopheles darlingi, the main vector of malaria in Paraguay, was not found. However, species richness indices (Chao/ACE) suggest that cryptic or sibling species may be present. Finally, the possible succession of Anopheles species and their geographical segregation are discussed in scenarios of entomological surveillance and epidemiological risk. Full article
(This article belongs to the Special Issue Emerging Technologies and Approaches for the Prevention and Treatment of Zoonotic Diseases)
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