Pseudovirus-Based Strategies for Understanding and Controlling Viral Infections
A special issue of Pathogens (ISSN 2076-0817).
Deadline for manuscript submissions: 31 December 2025 | Viewed by 26
Special Issue Editor
Interests: SARS-CoV-2; HIV-1; HPV; vaccine development; vaccine evaluation; immune response; neutralizing antibody; standardization of assay
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Pseudoviruses have become indispensable tools in biomedical research, serving as vital surrogates for authentic viruses across multiple applications. In broad terms, these recombinant constructs are defined by their incorporation of foreign genetic material, regardless of whether they display exogenous surface proteins. This versatile category has application in understanding the infectivity mechanisms, gene therapy delivery systems, vaccine vector development, and diagnostic control materials for nucleic acid assays.
Despite significant progress in pseudovirus development for emerging pathogens, substantial technical challenges persist. Current limitations include a lack of universal construction strategies, persistent technical barriers for certain virus families (e.g., flaviviruses), and inconsistent standardization across research groups.
Hence, this Special Issue, titled “Pseudovirus-Based Strategies for Understanding and Controlling Viral Infections”, promotes studies that focus on advanced pseudovirus packaging strategies; their use in studies of virus life cycles; emerging applications in vaccines, therapeutics, and diagnostics; and any other fields related to pseudovirses.
Dr. Jianhui Nie
Guest Editors
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Keywords
- pseudovirus
- infectivity
- neutralization
- antigenicity
- immunogenicity
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