Infectious Diseases in Pediatric Populations: Clinical Challenges and Emerging Perspectives

A special issue of Pathogens (ISSN 2076-0817).

Deadline for manuscript submissions: 31 January 2026 | Viewed by 41

Special Issue Editors


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Guest Editor
Unit of Pediatric Clinic, Department of Clinical and Experimental Medicine, University of Catania, AOU Policlinico, PO G. Rodolico, Via S. Sofia, 78, 95124 Catania, Italy
Interests: paediatric infectious diseases; paediatric neurology; neonatology; paediatric pharmacology
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
1. Postgraduate Training Programme in Pediatrics, Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy
2. Neonatal Intensive Care Unit, AOU Policlinico G. Rodolico San Marco, 95123 Catania, Italy
Interests: paediatric infectious diseases; paediatric neurology; neonatology; paediatric pharmacology

E-Mail Website
Guest Editor
Unit of Pediatric Clinic, Department of Clinical and Experimental Medicine, University of Catania, AOU Policlinico, PO G. Rodolico, Via S. Sofia, 78, 95124 Catania, Italy
Interests: paediatric infectious diseases; paediatric neurology; neonatology; paediatric pharmacology

Special Issue Information

Dear Colleagues,

Infectious diseases remain a major global health concern in pediatric populations, especially in infants and young children with developing immune systems. While clinical manifestations, diagnostic challenges, and therapeutic strategies are continuously evolving, there is increasing interest in understanding the molecular and immunological dynamics of infections in children, as well as the potential long-term consequences, including post-infectious syndromes and neurodevelopmental outcomes.

This Special Issue of Pathogens aims to bring together original research and reviews that focus on infectious diseases in neonates, infants, and children, with a particular emphasis on the following topics:

  • Clinical presentations, diagnosis, and treatment of bacterial, viral, fungal, and parasitic infections;
  • Host–pathogen interactions and the role of the developing immune system;
  • Molecular and cellular mechanisms driving infection progression or resolution;
  • Emerging pathogens and changing patterns of pathogen transmission in pediatric cohorts;
  • Post-infectious complications, including post-COVID-19 syndromes, post-infectious autoimmune phenomena, chronic inflammation, and neurodevelopmental impairments.

We especially encourage contributions that explore the pathogen-induced modulation of immune responses, cellular signaling, and host adaptation in pediatric hosts, as well as those that provide insight into vaccine development, preventive strategies, clinical presentations, and diagnosis, and long-term follow-up studies on children affected by infectious diseases.

Both experimental and clinical studies are welcome, as well as case series, systematic reviews, and conceptual articles offering new hypotheses and future directions. This Special Issue will offer a multidisciplinary platform to deepen our understanding of pediatric infections and promote more precise, age-appropriate interventions.

Dr. Piero Pavone
Dr. Roberta Leonardi
Dr. Manuela Lo Bianco
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pediatric infectious diseases and immune responses
  • post-infectious syndromes
  • diagnosis and treatment of pediatric infectious diseases
  • pediatric microbiome
  • viral, fungal, and bacterial infections in children

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Published Papers

This special issue is now open for submission.
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