Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Advances in Crop Genetics and Breeding: 2nd Edition
edited by , , and Long Chen
submission deadline 15 May 2026 | Viewed by 58 | Submission Open
Keywords: crop; high-throughput genotyping; genetic resources; favorable haplotype; marker-assisted selection; genome editing; CRISPR-Cas9; genomic selection
(This special issue belongs to the Section Plant Science)
Cancer Epidemiology
edited by Daniela-Cristina Stefan and Honoré K. Mitonga
submission deadline 18 May 2026 | 6 articles | Viewed by 8728 | Submission Open
Keywords: cancer disparities; specific populations; methodological advances; cancer trends; cancer causes; prevention strategies
(This special issue belongs to the Section Epidemiology)
Vestibular Disorders: Pathogenesis and Modern Diagnostic Approaches
edited by Kazimierz Niemczyk and Agnieszka Jasińska-Nowacka
submission deadline 18 May 2026 | Viewed by 38 | Submission Open
Keywords: vestibular disorders; Mé niè re’ s disease; vestibular migraine; vertigo; perilymph; endolymph
(This special issue belongs to the Section Medical Research)
Emerging Applications of Nanobiotechnology in Medicine and Health
edited by Roshanak Khandanlou
submission deadline 19 May 2026 | 1 articles | Viewed by 666 | Submission Open
Keywords: nanobiotechnology; targeted drug-delivery; tissue engineering; cancer treatment; regenerative medicine; medical applications
(This special issue belongs to the Section Medical Research)
Wildlife Shifts: Species, Space, and Survival
edited by Nikolay D. Natchev
submission deadline 19 May 2026 | Viewed by 41 | Submission Open
Keywords: ecological transitions; behavior; adaptation; organisms; habitat specifics
(This special issue belongs to the Section Animal Science)
Environmental Contaminants: Impacts on Reproduction and Embryonic Development submission deadline 20 May 2026 | 1 articles | Viewed by 699 | Submission Open
Keywords: environmental contaminants; embryonic development; fertility; toxicity; chemicals
(This special issue belongs to the Section Reproductive and Developmental Biology)
Diagnosis and Management of Maternal Medical Diseases in Pregnancy: Current Practice and Future Perspectives submission deadline 20 May 2026 | Viewed by 74 | Submission Open
Keywords: maternal medical disease; maternal cardiac disease; maternal thyroid disease; gestational diabetes; gestational hypertension; pre-eclampsia; diagnosis; management; maternal and fetal outcomes
(This special issue belongs to the Section Medical Research)
Clinical and Radiological Perspectives in Rhinosinusal Pathology submission deadline 20 May 2026 | Viewed by 45 | Submission Open
Keywords: chronic rhinosinusitis; CBCT; CT; acute rhinosinusitis; maxillary rhinosinusitis; ethmoidal air cells variants; maxillary sinus; Haller cells; Onodi cells; concha bullosa; Agger nasi cells
(This special issue belongs to the Section Medical Research)
Advances in Cardiac Arrhythmias: Mechanisms, Diagnostics and Therapeutics submission deadline 22 May 2026 | 1 articles | Viewed by 802 | Submission Open
Keywords: cardiac electrophysiology; arrhythmias; inherited channelopathies
(This special issue belongs to the Section Medical Research)
From Animal Models to Clinical Innovations: Translating Research into Medicine submission deadline 22 May 2026 | Viewed by 224 | Submission Open
Keywords: animal models; animal research; biomedical research; ethics of animal experimentation; experimentation on animals; interspecies differences; translational medicine; human clinical medicine
(This special issue belongs to the Section Animal Science)
Advanced Cardiovascular Imaging in Heart Failure and Cardio-Oncology: From Early Detection to Personalized Prognosis submission deadline 22 May 2026 | Viewed by 34 | Submission Open
Keywords: advanced cardiovascular imaging; heart failure; cardio-oncology; global longitudinal strain; cardiac magnetic resonance; PET/CT imaging; artificial intelligence; risk stratification; cardiotoxicity; precision medicine
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
Progress and Challenges in Emerging Therapies for Alzheimer’s Disease and Its Comorbidities submission deadline 22 May 2026 | Viewed by 31 | Submission Open
Keywords: Alzheimer’ s disease; emerging therapies/novel treatments; multimorbidity/comorbidities; translational research; cognitive decline; drug development; innovative approaches
(This special issue belongs to the Section Medical Research)
Nutritional Supplementation, Body Composition and Performance in Athletes
edited by
submission deadline 25 May 2026 | 2 articles | Viewed by 19395 | Submission Open
Keywords: optimal macro and micronutrients in exercise; plant-based food in sports nutrition; beetroot as ergogenic aid; body mass composition and nutrition practice; phase angle as VO2 max predictor; RED syndrome low and high energetic availability in sports praxis
(This special issue belongs to the Section Physiology and Pathology)
Current Advances in Diagnosis and Treatment of Sepsis
edited by Chih-Huang Li
submission deadline 25 May 2026 | 5 articles | Viewed by 10345 | Submission Open
Keywords: sepsis; biomarkers; prediction; immunotherapy; AI model
(This special issue belongs to the Section Medical Research)
Advancements in Cardiovascular Epidemiology: Integrating Predictive Modeling into Public Health
edited by and Matina Kouvari
submission deadline 25 May 2026 | 1 articles | Viewed by 7421 | Submission Open
Keywords: CVD epidemiology; public health interventions; predictive modeling; risk stratification; cardiometabolic risk factors
(This special issue belongs to the Section Epidemiology)
Animal Nutritional Physiology: Effects of Feed Additives on Livestock Products
edited by and Katarzyna Poltowicz
submission deadline 25 May 2026 | Viewed by 984 | Submission Open
Keywords: feed additives; animal health; animal performance; animal-derived products; animal nutritional physiology
(This special issue belongs to the Section Physiology and Pathology)
Molecular Signatures and Biomarkers in Human Diseases
edited by Manuela Montanaro and Alfonso Baldi
submission deadline 25 May 2026 | Viewed by 27 | Submission Open
Keywords: biomarkers; therapeutic biomarkers; circulating biomarkers; molecular signatures; molecular imaging; precision medicine; targeted therapies; technological innovations
(This special issue belongs to the Section Medical Research)
Coronary Artery Disease: Pathophysiological Mechanisms, Imaging Modalities and Therapeutic Implications
edited by and Filippo Luca Gurgoglione
submission deadline 26 May 2026 | 5 articles | Viewed by 13660 | Submission Open
Keywords: coronary artery disease; coronary atherosclerosis; atherosclerotic plaque progression; coronary imaging; cardiovascular risk factors and coronary atherosclerosis-associated diseases
(This special issue belongs to the Section Medical Research)
Pediatric Cardiology Frontiers: Innovations in Diagnosis and Treatment submission deadline 26 May 2026 | 3 articles | Viewed by 3110 | Submission Open
Keywords: congenital heart disease; cardiovascular imaging; minimally invasive interventions; fetal cardiology; transcatheter therapies; artificial intelligence in cardiology; 3D echocardiography; cardiac MRI; personalized medicine; genetic heart disorders; heart failure in children; robotic-assisted surgery; cardiovascular biomarkers; electrophysiology in pediatrics; innovative surgical techniques; early diagnosis of heart disease; emerging therapies in cardiology
(This special issue belongs to the Section Medical Research)
Advances in Endoscopy for Hepatic, Pancreatic, and Biliary Diseases
edited by
submission deadline 26 May 2026 | 1 articles | Viewed by 1786 | Submission Open
Keywords: endoscopic intervention; endoscopic ultrasound; lumen apposing metal stent; radiofrequency ablation; endoscopic sleeve gastroplasty; cholangioscopy; endoscopic retrograde cholangiopancreatography; liver disease; biliary disease; pancreatobiliary disease
(This special issue belongs to the Section Medical Research)
Gynecological Endocrinology: From Physiological Mechanisms to Clinical Practice: 2nd Edition
edited by Ralitsa Robeva
submission deadline 27 May 2026 | Viewed by 82 | Submission Open
Keywords: PCOS; hypothalamic amenorrhea; congenital adrenal hyperplasia; hypogonadotropic hypogonadism; premature ovarian insufficiency (POI)
(This special issue belongs to the Section Physiology and Pathology)
Metabolic Health: The Interplay Between NAFLD, MAFLD, MASLD and Cardiovascular Disease
edited by and Monika Różycka-Kosmalska
submission deadline 28 May 2026 | 7 articles | Viewed by 10192 | Submission Open
Keywords: non-alcoholic fatty liver disease (NAFLD); metabolic-dysfunction-associated fatty liver disease (MAFLD); metabolic-dysfunction-associated steatotic liver disease (MASLD); cardiovascular disease (CVD); cardiac arrhythmias; structural heart disease; coronary artery disease; hypertension
(This special issue belongs to the Section Medical Research)
Advanced Research in Exercise Medicine
edited by
submission deadline 28 May 2026 | 3 articles | Viewed by 10048 | Submission Open
Keywords: exercise and chronic disease; cardiovascular dysfunction/disease; metabolic syndrome; aging; athletic training; sports medicine; rehabilitation
(This special issue belongs to the Section Physiology and Pathology)
Advances in Pulmonology: Transforming Diagnosis and Treatment of Lung Diseases submission deadline 28 May 2026 | 2 articles | Viewed by 2023 | Submission Open
Keywords: biomarkers in lung diseases; sleep disorders; chronic obstructive diseases; interstitial lung diseases; thoracic surgery
(This special issue belongs to the Section Medical Research)
Diagnosis and Treatment of Orthopedic Diseases: Advancing Arthroscopy submission deadline 28 May 2026 | 1 articles | Viewed by 1176 | Submission Open
Keywords: arthroscopy; knee; hip; shoulder; arthroscopic surgery
(This special issue belongs to the Section Medical Research)
Microglia, Behavior, and Sex Differences: Neuroimmune Mechanisms in Development and Disease
edited by Irene García Domínguez
submission deadline 28 May 2026 | Viewed by 53 | Submission Open
Keywords: microglia; neuroinflammation; sex differences; neurodevelopment; behavior; neuroimmune mechanisms; brain disorders
(This special issue belongs to the Section Physiology and Pathology)
The 15th Anniversary of Life—Alternatives to RNA World
edited by and Amit Kahana
submission deadline 29 May 2026 | Viewed by 337 | Submission Open
Keywords: supramolecular; lipid; assembly; protocell; compositional; information; spontaneous; catalytic; network; reproduction; species; Darwinian; evolution; origin; life
(This special issue belongs to the Section Origin of Life)
Musculoskeletal Disorders: Integrative Insights into Pathophysiology, Therapeutic Strategies, and Rehabilitation
edited by
submission deadline 30 May 2026 | Viewed by 132 | Submission Open
Keywords: musculoskeletal disorders; high-resolution imaging; biomarkers; ultrasound-guided therapy; regenerative medicine; personalized rehabilitation; wearable sensors; translational musculoskeletal research
(This special issue belongs to the Section Medical Research)
The Role of Natural Products in Disease Treatment submission deadline 30 May 2026 | Viewed by 74 | Submission Open
Keywords: natural products; bioactive compounds; functional foods and nutraceuticals; disease prevention and treatment
(This special issue belongs to the Section Plant Science)
New Mechanisms and Insights into Insect Silk Gland Biology and Silk Production
edited by Wenliang Qian
submission deadline 30 May 2026 | Viewed by 67 | Submission Open
Keywords: silk gland morphogenesis; liquid-to-solid phase transition; biomimetic microfluidic spinning; silk gland multi-omics; silk protein evolutionary adaptations; CRISPR
(This special issue belongs to the Section Animal Science)
Current Approaches and Future Directions in the Treatment of Gynecologic Tumors: Molecular Biology, Diagnostic Advancements and Targeted Therapeutic Strategies—2nd Edition submission deadline 30 May 2026 | Viewed by 23 | Submission Open
Keywords: gynecologic tumors; cervical cancer; ovarian cancer; endometrial cancer; vulvar cancer; vaginal cancer; gestational trophoblastic disease; molecular mechanisms; diagnostic advancements; novel therapies
(This special issue belongs to the Section Medical Research)
Advances in Skin-Related Disease: Pathogenesis and Novel Therapeutic Strategies submission deadline 31 May 2026 | 4 articles | Viewed by 8010 | Submission Open
Keywords: skin pathologies; skin cancer; eczema; acne; psoriasis; skin microbiome
(This special issue belongs to the Section Physiology and Pathology)
Prognosis and Management of Dry Eye Disease submission deadline 31 May 2026 | 3 articles | Viewed by 7433 | Submission Open
Keywords: dry eye disease; dry eye epidemiology; dry eye management; dry eye natural course; meibomian gland dysfunction; evaporative dry eye; aqueous deficiency dry eye; artificial tear substitutes; tear film lipid layer; meibomian glands
(This special issue belongs to the Section Medical Research)
New Insights into Pediatric Rheumatic and Autoimmune Diseases
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 2649 | Submission Open
Keywords: arthritis; juvenile; autoimmune diseases; biomarkers; diagnostic imaging; juvenile dermatomyositis; lupus erythematosus; systemic; pediatric rheumatology; vasculitis
(This special issue belongs to the Section Medical Research)
Current and Future Perspectives of Takotsubo Syndrome
edited by Luca Arcari
submission deadline 31 May 2026 | 2 articles | Viewed by 2030 | Submission Open
Keywords: takotsubo syndrome; heart failure; microvascular dysfunction; inflammation; myocardial edema; heart– brain axis; echocardiography; cardiac magnetic resonance; computed tomography; nuclear imaging
(This special issue belongs to the Section Physiology and Pathology)
Recent Advances in Lymphomas
edited by Magdalena Witkowska
submission deadline 31 May 2026 | 2 articles | Viewed by 2020 | Submission Open
Keywords: lymphoma; cellular therapy; epigenetics; immunotherapy; targeted therapies
(This special issue belongs to the Section Medical Research)
Advances in Wildlife Behavior and Biodiversity submission deadline 31 May 2026 | 1 articles | Viewed by 1033 | Submission Open
Keywords: behavioral abnormalities; the ability to exhibit natural behavior; reduced genetic diversity; habitat loss; extinction of species; species rehousing; coexistence
(This special issue belongs to the Section Diversity and Ecology)
Innovative Cardiovascular Interventions: From Imaging to Precision Therapies submission deadline 31 May 2026 | 1 articles | Viewed by 1030 | Submission Open
Keywords: cardiovascular diseases (CVDs); diagnostic imaging; minimally invasive interventions; precision medicine; 3D/4D imaging; gene therapy; cell-based therapies
(This special issue belongs to the Section Physiology and Pathology)
Harmful Algal Bloom Risk: Mechanisms, Prediction, Impacts and Mitigation
edited by Lixia Shang
submission deadline 31 May 2026 | 1 articles | Viewed by 478 | Submission Open
Keywords: harmful algal blooms; marine risk; bloom mechanisms; prediction models; mitigation strategies; ecosystem impact
(This special issue belongs to the Section Diversity and Ecology)
New Screening Methods for Diagnosis of Cardiovascular Diseases
edited by , Ruxandra Maria Ilie-Mihai and Damaris Cristina Gheorghe
submission deadline 31 May 2026 | Viewed by 115 | Submission Open
Keywords: cardiovascular diseases; biomarkers; screening methods; sensor; spectroscopic methods; chromatographic methods
(This special issue belongs to the Section Medical Research)
Physiological, Pathological, and Clinical Effects of Exercise Training and Physical Activity
edited by Chia-Huei Lin
submission deadline 31 May 2026 | Viewed by 109 | Submission Open
Keywords: exercise training; physical activity; individualized exercise prescription; physiological adaptation; chronic disease prevention; cardiovascular fitness; musculoskeletal health; neuroplasticity; metabolic syndrome; inflammation and immunity; stroke recovery; physical activity monitoring; mental health and exercise; cognitive function; aging and physical activity; sedentary behavior; physical function outcomes; patient-reported outcomes; clinical trial
(This special issue belongs to the Section Physiology and Pathology)
Hybrid Molecules in Drug Discovery from Antidiabetic Agents to Anticancer Therapeutics
edited by Jatinder Singh and Shreyosree Chatterjee
submission deadline 31 May 2026 | Viewed by 103 | Submission Open
Keywords: hybrid molecules; drug discovery; antidiabetic; oncology; structure— activity relationships
(This special issue belongs to the Section Pharmaceutical Science)
Biofluid Mechanics and Medical Diagnostic Simulations submission deadline 31 May 2026 | Viewed by 94 | Submission Open
Keywords: biofluid mechanics; computational modeling; medical diagnostics; fluid-structure interaction; patient-specific modeling
(This special issue belongs to the Section Medical Research)
Understanding Early Dysmetabolism in Adolescents: Bridging Research, Mechanisms and Clinical Management
edited by Anna Di Sessa
submission deadline 31 May 2026 | Viewed by 81 | Submission Open
Keywords: dysmetabolism; biomarkers; intervention; prevention; early diagnosis; strategies; children; adolescents
(This special issue belongs to the Section Physiology and Pathology)
Artificial Intelligence and Machine Learning for Biomedical Diagnostics and Prognostics submission deadline 31 May 2026 | Viewed by 71 | Submission Open
Keywords: artificial intelligence; machine learning; diagnostic and prognostic modeling; multimodal data integration; explainable AI
(This special issue belongs to the Section Medical Research)
Gut Microbial Dysbiosis in the Pathogenesis of Gastrointestinal Disorders
edited by Giovanni Tomasello
submission deadline 31 May 2026 | Viewed by 48 | Submission Open
Keywords: gut dysbiosis; gastrointestinal; probiotics; inflammatory bowel diseases
(This special issue belongs to the Section Microbiology)
Comorbidities of Migraine: Clinical and Research Perspectives
edited by Claudio Tana
submission deadline 31 May 2026 | Viewed by 21 | Submission Open
Keywords: migraine; pain; headache; comorbidities; internal medicine; complex disorders
(This special issue belongs to the Section Medical Research)
Objective Tools to Aid the Diagnosis and Treatment of Neurodevelopmental Disorders
edited by Maria Pia Bucci
submission deadline 31 May 2026 | Viewed by 7 | Submission Open
Keywords: intervertion training  ; eye tracker  ; dyslexia  ; postural sways  ; reading  ; ASD  ; ADHD  ; attention  ; emotion
(This special issue belongs to the Section Medical Research)
Epidemiological Insights into Cardiovascular Risk and Outcomes
edited by Rui Providência
submission deadline 8 Jun 2026 | Viewed by 40 | Submission Open
Keywords: cohort study; Mendelian randomization; myocardial infarction; heart failure; stroke; atrial fibrillation; risk prediction
(This special issue belongs to the Section Epidemiology)
Ultrasound and Anatomical Studies
edited by , Ingrid Moller and Albert Pérez-Bellmunt
submission deadline 15 Jun 2026 | Viewed by 90 | Submission Open
Keywords: ultrasound techniques; musculoskeletal system; human anatomy; medicine specialties; clinical students; ultrasound teaching
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
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