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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Pulmonary Hypertension: From Pathophysiology to Clinical Management
edited by and
submission deadline 19 Mar 2027 | 1 articles | Viewed by 1409 | Submission Open
Keywords: pulmonary hypertension; pulmonary arterial hypertension; chronic thromboembolic pulmonary hypertension; pulmonary endarterectomy; balloon pulmonary angioplasty; pharmacological treatment; pathophysiology
(This special issue belongs to the Section Respiratory Medicine)
Insights and Innovations in Sports Cardiology submission deadline 20 Mar 2027 | 7 articles | Viewed by 15128 | Submission Open
Keywords: sports cardiology; athlete heart; cardiovascular screening; arrhythmias; sudden cardiac death; cardiac rehabilitation; exercise prescription; mobile health; preventive cardiology; personalized medicine; pediatric fitness
(This special issue belongs to the Section Sports Medicine)
Acute Myocardial Infarction: Diagnosis, Treatment, and Rehabilitation
edited by
submission deadline 20 Mar 2027 | 9 articles | Viewed by 12176 | Submission Open
Keywords: acute myocardial infarction; coronary angioplasty; acute heart failure; cardiogenic shock; rehabilitation programs
(This special issue belongs to the Section Cardiovascular Medicine)
Acute Coronary Syndrome(ACS): From Emergency Intervention to Long-Term Prevention
edited by Marco Ciardetti and Alessio Mattesini
submission deadline 20 Mar 2027 | 4 articles | Viewed by 9168 | Submission Open
Keywords: acute coronary syndrome; primary percutaneous coronary intervention; antithrombotic therapy; secondary prevention; risk stratification
(This special issue belongs to the Section Cardiology)
Sarcopenia, Musculoskeletal, and Neuromuscular Disorders: Physical Therapy and Rehabilitation Perspectives submission deadline 20 Mar 2027 | 2 articles | Viewed by 7542 | Submission Open
Keywords: sarcopenia; musculoskeletal diseases; neuromuscular disorders; muscle mass; low back pain; neck pain; gait and balance; physical therapy; rehabilitation medicine
(This special issue belongs to the Section Clinical Rehabilitation)
Artificial Intelligence in Gastrointestinal Disorders: Current Updates from Theory to Clinical Practice submission deadline 20 Mar 2027 | 5 articles | Viewed by 5802 | Submission Open
Keywords: artificial intelligence; gastroenterology; medical imaging; endoscopy; prognostic modeling; ethical considerations
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Obesity-Related Metabolic and Cardiovascular Disorders
edited by and Federica Vinciguerra
submission deadline 20 Mar 2027 | 5 articles | Viewed by 5159 | Submission Open
Keywords: obesity; type 2 diabetes mellitus; insulin resistance; metabolic syndrome; cardiovascular disease; lipid disorder; adipose tissue dysfunction; visceral adiposity; cardiometabolic risk; endothelial dysfunction; health disparities; gut microbiota; bariatric surgery; precision medicine
(This special issue belongs to the Section Cardiovascular Medicine)
State of the Art in Spinal Cord Injuries: Clinical Rehabilitation and Management
edited by
submission deadline 20 Mar 2027 | 6 articles | Viewed by 4538 | Submission Open
Keywords: neurorehabilitation; assistive technologies; neuroplasticity; neuromodulation; spinal cord injury
(This special issue belongs to the Section Clinical Rehabilitation)
Pre-Hospital and In-Hospital Emergency Care Research
edited by , and Yohei Okada
submission deadline 20 Mar 2027 | 8 articles | Viewed by 4532 | Submission Open
Keywords: pre-hospital; in-hospital; emergency care; emergency medical services; acute care
(This special issue belongs to the Section Emergency Medicine)
Diagnosis, Treatment and Prognosis of Head and Neck Cancer
edited by and Elena Russo
submission deadline 20 Mar 2027 | 5 articles | Viewed by 3894 | Submission Open
Keywords: head and neck neoplasms; surgical procedures; minimally invasive surgical procedures; radiotherapy; immunotherapy; biomarkers; treatment outcome; early diagnosis; prognosis; quality of life
(This special issue belongs to the Section Oncology)
Advances in Pacemaker Implantation: Past, Present, and Future Challenges
edited by Rahul N. Doshi and
submission deadline 20 Mar 2027 | 1 articles | Viewed by 3759 | Submission Open
Keywords: pacing; physiologic pacing; left bundle area pacing; leadless pacing; lead management
(This special issue belongs to the Section Cardiology)
Trauma Surgery: Strategies, Challenges and Vision of the Future
edited by and Yaniv S. Warschawski
submission deadline 20 Mar 2027 | 3 articles | Viewed by 3639 | Submission Open
Keywords: orthopaedic surgery; fractures; injuries; upper limb; trauma
(This special issue belongs to the Section Clinical Research Methods)
Clinical Updates in Fractures: Orthopedics, Trauma Surgery, and Rehabilitation
edited by
submission deadline 20 Mar 2027 | 3 articles | Viewed by 3168 | Submission Open
Keywords: orthopedic surgery; global orthopedic health; surgical techniques; outreach; inreach; artificial intelligence; robotics; outcome measures
(This special issue belongs to the Section Orthopedics)
Misconceptions and Myths in Dermatology: From Clinic to Clarity
edited by Simon M. Mueller and Oliver Brandt
submission deadline 20 Mar 2027 | 1 articles | Viewed by 3099 | Submission Open
Keywords: misconceptions; misunderstanding; myths; errors; mistakes; skin; dermatology
(This special issue belongs to the Section Dermatology)
Clinical Diagnosis and Treatment in Oncology: Radiotherapy and Imaging Analysis submission deadline 20 Mar 2027 | 1 articles | Viewed by 2961 | Submission Open
Keywords: radiomics; metabolic imaging; radiotherapy; predictive factors; response models; PET-CT; artificial intelligence; biomarkers; machine-learning
(This special issue belongs to the Section Oncology)
Recent Advances in Adverse Pregnancy and Neonatal Outcomes
edited by
submission deadline 20 Mar 2027 | 2 articles | Viewed by 2825 | Submission Open
Keywords: maternal and fetal; adverse pregnancy; neonatal outcomes; newborns; cesarean section
(This special issue belongs to the Section Obstetrics & Gynecology)
Spine Surgery: Clinical Advances and Practice Updates
edited by
submission deadline 20 Mar 2027 | 3 articles | Viewed by 2738 | Submission Open
Keywords: spine surgery; minimally invasive spine surgery; endoscopic spine surgery; robotics; artificial intelligence; spinal deformity; scoliosis; spinal trauma
(This special issue belongs to the Section Orthopedics)
Current Advances in Non-Trauma Emergency Critical and Resuscitation Medicine
edited by
submission deadline 20 Mar 2027 | 1 articles | Viewed by 2572 | Submission Open
Keywords: resuscitation; non-trauma critically ill; emergency department; resuscitation room management; neuro-critical emergency care; emergency department critical care
(This special issue belongs to the Section Emergency Medicine)
Clinical Challenges in Heart Failure Management: 2nd Edition
edited by Paolo Severino, Gaetano M. Ruocco and
submission deadline 20 Mar 2027 | 2 articles | Viewed by 2557 | Submission Open
Keywords: acute heart failure; chronic heart failure; inotropic support; left ventricular assist device; cardiac contractility modulation; guanylate cyclase stimulators; quality of life; telemedicine; palliative care
(This special issue belongs to the Section Cardiology)
Current Challenges in Adult Congenital Heart Diseases submission deadline 20 Mar 2027 | 3 articles | Viewed by 2309 | Submission Open
Keywords: adult congenital heart disease; quality of life; pregnancy in congenital heart disease; heart failure; arrhythmia; septal defect; congenital valve stenosis; coarctation of the Aorta; Fontan circulation; Tetralogy of Fallot
(This special issue belongs to the Section Cardiology)
Current Updates on Pediatric Neurological Disorders and Neurorehabilitation submission deadline 20 Mar 2027 | 2 articles | Viewed by 1858 | Submission Open
Keywords: child neurological disorders; neurorehabilitation; neurogenetics; treatment; quality of life; rehabilitation teams; congenital brain disorders; trauma; movement disorders; cerebral palsy
(This special issue belongs to the Section Clinical Pediatrics)
Perspectives in Bionic Reconstruction and Post-Amputation Management
edited by and Jennifer Ernst
submission deadline 20 Mar 2027 | 2 articles | Viewed by 1852 | Submission Open
Keywords: bionic reconstruction; advanced prosthetics; neurorehabilitation; sensory feedback; motor control
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Clinical Advances in Lower Limb Trauma and Orthopedic Surgery: From Bench to Bedside
edited by and
submission deadline 20 Mar 2027 | 3 articles | Viewed by 1834 | Submission Open
Keywords: lower limb trauma; fracture fixation; arthroplasty; biomechanics; orthopaedic surgery; clin-ical outcomes; minimally invasive techniques; rehabilitation
(This special issue belongs to the Section Orthopedics)
Minimally Invasive Spine Surgery: Evidence, Advances and Controversies
edited by , Constantine Constantoyannis, and Oliver Lasry
submission deadline 20 Mar 2027 | 1 articles | Viewed by 1702 | Submission Open
Keywords: spine surgery; minimally invasive; MIS; MISS; endoscopic; tubular; fusion; laminectomy; discectomy; decompression; percutaneous; robotic; robotic-assisted; navigation; augmented-reality
(This special issue belongs to the Section Clinical Neurology)
Novel Perspectives in Transcatheter Aortic Valve Implantation
edited by Nay Min Htun
submission deadline 20 Mar 2027 | 1 articles | Viewed by 1647 | Submission Open
Keywords: TAVI; life-time management; TAVI-in-TAVI; bicuspid valve; pure aortic regurgitation; small annuli
(This special issue belongs to the Section Cardiology)
Gynecologic Cancers: Current Clinical Management and Multidisciplinary Treatment Strategies submission deadline 20 Mar 2027 | 1 articles | Viewed by 1527 | Submission Open
Keywords: gynecologic; cancer; uterus; ovarian; endometrial; cervical
(This special issue belongs to the Section Obstetrics & Gynecology)
Management of Diabetes-Related Cardiovascular Disease: Current Treatment and Future Options
edited by Antonio J. Amor and Tonet Serés-Noriega
submission deadline 20 Mar 2027 | 1 articles | Viewed by 1458 | Submission Open
Keywords: type 1 diabetes; type 2 diabetes; cardiovascular disease; biomarkers; atherosclerosis; cardioprotective drugs; vascular ultrasound
(This special issue belongs to the Section Cardiovascular Medicine)
Cataract and Refractive Surgery, and Intraocular Lens (IOL) Implantation: Advancing Diagnosis and Management
edited by Olga Reitblat
submission deadline 20 Mar 2027 | 3 articles | Viewed by 1427 | Submission Open
Keywords: cataract surgery; premium intraocular lenses (IOLs); IOL power calculation; visual outcomes; refractive cataract surgery; multifocal IOL; extended depth of focus (EDOF) IOL; toric IOL; full range; vision IOL; biometry
(This special issue belongs to the Section Ophthalmology)
New Perspective of Oral and Maxillo-Facial Surgery: 2nd Edition
edited by , and Alessandra Lucchese
submission deadline 20 Mar 2027 | 3 articles | Viewed by 1416 | Submission Open
Keywords: maxillofacial surgery; esthetic surgery; orthognatic surgery; TMJ disorders; TMJ surgery; dental implant surgery; 3D imaging; printing applications; tissue engineering; personalized treatment planning; artificial intelligence; squamous cell carcinoma; skin tumors; plastic and reconstructive surgery; head and neck surgery; ENT surgery
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Outcomes in Lumbar Spinal Stenosis Treatment
edited by Rafał Staszkiewicz and
submission deadline 20 Mar 2027 | 2 articles | Viewed by 1412 | Submission Open
Keywords: lumbar spinal stenosis; clinical outcomes; decompression surgery; conservative management; molecular biomarkers; inflammation and fibrosis; neurotrophic factors; personalized medicine; siganling pathways; quality of life
(This special issue belongs to the Section Orthopedics)
Orthodontics: Current Management and Future Options
edited by Arūnas Vasiliauskas and Aistė Kavaliauskienė
submission deadline 20 Mar 2027 | 3 articles | Viewed by 1384 | Submission Open
Keywords: digital orthodontics; clear aligner therapy; accelerated tooth movement; micro-implants; artificial intelligence; patient-centred outcomes; treatment efficiency
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Current Therapeutic Approaches to Addictive Disorders
edited by Linda Haddad
submission deadline 20 Mar 2027 | 1 articles | Viewed by 1195 | Submission Open
Keywords: addiction treatment; dependence; withdrawal management; relapse prevention; recovery; rehabilitation and support
(This special issue belongs to the Section Mental Health)
Novel Research in Cardiovascular Imaging
edited by Stanciu Silviu and
submission deadline 20 Mar 2027 | 1 articles | Viewed by 1183 | Submission Open
Keywords: echocardiography; cardiac CT; CMR; nuclear medicine; artificial intelligence
(This special issue belongs to the Section Cardiovascular Medicine)
Advances in Interventional Cardiology: From Access to Outcomes
edited by James Cotton and Benjamin Wrigley
submission deadline 20 Mar 2027 | 2 articles | Viewed by 1117 | Submission Open
Keywords: interventional cardiology; acute coronary syndrome; chronic coronary syndrome; TAVI; TAVR; TEER; TMVR; T-TEER; TTVR; service redesign
(This special issue belongs to the Section Cardiology)
Pulmonary Hypertension and Chronic Lung Disease: Diagnosis and Management submission deadline 20 Mar 2027 | 1 articles | Viewed by 1086 | Submission Open
Keywords: pulmonary hypertension; chronic obstructive pulmonary disease (COPD); chronic lung disease; epidemiology; exacerbations; comorbidities; risk factors; diabetes; systemic inflammation; real-world data
(This special issue belongs to the Section Respiratory Medicine)
Diagnosis and Treatment of Pleura and Lung: Clinical Advances in Intensive Care submission deadline 20 Mar 2027 | 1 articles | Viewed by 1063 | Submission Open
Keywords: thoracic drainage; lung recruitment; lung ultrasound; pleural effusion; pneumothrax; B-line; lung atelectasis
(This special issue belongs to the Section Intensive Care)
Updates on Reconstructive Urology
edited by
submission deadline 20 Mar 2027 | 1 articles | Viewed by 986 | Submission Open
Keywords: reconstructive urology; urethral stenosis; urethroplasty; urethral diverticulum; ureteral stenosis; male incontinence; urinary diversion; hypospadias; microsurgery; experimental microsurgery; bladder diverticulum; neobladder
(This special issue belongs to the Section Nephrology & Urology)
Rebuilding the Knee: From Repair to Replacement and Recovery
edited by Young-Jin Seo
submission deadline 20 Mar 2027 | 2 articles | Viewed by 956 | Submission Open
Keywords: cartilage; meniscus; total knee arthroplasty; knee surgery; anterior cruciate ligament injuries; posterior cruciate ligament injuries; ligament reconstruction; patellofemoral disorders; osteotomy; sports medicine; rehabilitation; functional recovery
(This special issue belongs to the Section Orthopedics)
New Insights in Trauma and Emergency Surgery
edited by Kai Oliver Jensen and Valentin Neuhaus
submission deadline 20 Mar 2027 | 1 articles | Viewed by 898 | Submission Open
Keywords: trauma and emergency surgery; multiple trauma; orthopedic trauma; surgery; concepts in trauma
(This special issue belongs to the Section Emergency Medicine)
What We See Through Cardiac Imaging: Second Edition submission deadline 20 Mar 2027 | 1 articles | Viewed by 877 | Submission Open
Keywords: cardiomyopathies; multimodality imaging; echocardiography; cardiac-computed tomography; cardiac magnetic resonance; prognosis; arrhythmias; heart failure
(This special issue belongs to the Section Cardiology)
Digital Innovations in Obstetrics and Gynecology: Artificial Intelligence, Diagnostic Advances, Minimally Invasive Surgery, and Clinical Decision-Making
edited by
submission deadline 20 Mar 2027 | 2 articles | Viewed by 834 | Submission Open
Keywords: obstetrics; gynecology; artificial intelligence; machine learning; minimally invasive surgery; digital health
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Clinical Medicine)
Colorectal Surgery: Advances in Modern Clinical Management submission deadline 20 Mar 2027 | 1 articles | Viewed by 687 | Submission Open
Keywords: colorectal cancer management; surgery; complications; organ preservation; screening; colonic diverticular disease; colonic diverticulitis; hemorrhoids
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Hemophilia: Current Trends and Future Directions: 2nd Edition submission deadline 20 Mar 2027 | 1 articles | Viewed by 685 | Submission Open
Keywords: hemophilia; prophylaxis; gene therapy; burden of illness; quality of life; patient reported outcomes; hemarthrosis; women and hemophilia
(This special issue belongs to the Section Hematology)
Thyroid Cancer: Diagnosis, Surgical Treatment and Postoperative Radioactive Iodine Therapy: 2nd Edition
edited by Alfred A. Simental
submission deadline 20 Mar 2027 | 1 articles | Viewed by 681 | Submission Open
Keywords: thyroid nodule; thyroid ultrasound; radiofrequency ablation; molecular analysis; thyroid surgery
(This special issue belongs to the Section Oncology)
New Insights into Gastrointestinal Surgery: Advances in Techniques and Treatment Approaches
edited by Gabriella Teresa Capolupo
submission deadline 20 Mar 2027 | Viewed by 516 | Submission Open
Keywords: gastroenterology; gastrointestinal surgery; colorectal surgery; robotic surgery; technologies; minimally invasive surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Pediatric Orthopedics: Diagnosis, Treatment, and Comprehensive Management
edited by Michał Latalski and
submission deadline 20 Mar 2027 | 2 articles | Viewed by 515 | Submission Open
Keywords: pediatric orthopedics; cerebral palsy; SMA; spinal deformities; developmental dysplasia of the hip; clubfoot; neuro-orthopedics; gait analysis; pediatric traumatology; skeletal dysplasia; biomechanics; congenital musculoskeletal anomalies
(This special issue belongs to the Section Orthopedics)
Atrial Fibrillation: Contemporary Evidence from Prevention to Catheter Ablation
edited by , Radu Gabriel Vătăşescu and
submission deadline 20 Mar 2027 | 1 articles | Viewed by 513 | Submission Open
Keywords: atrial fibrillation; prevention; risk-factor modification; screening; rhythm control; catheter ablation; stroke prevention; outcomes
(This special issue belongs to the Section Cardiology)
Current Challenges and Innovation in Trauma and Acute Care Surgery
edited by Michel Teuben
submission deadline 20 Mar 2027 | Viewed by 478 | Submission Open
Keywords: traumatology; trauma surgery; acute care surgery; femur; injury
(This special issue belongs to the Section Emergency Medicine)
Exploring Diagnostic and Therapeutic Advances in Neurodegenerative Disorders submission deadline 20 Mar 2027 | 1 articles | Viewed by 402 | Submission Open
Keywords: neurodegenerative disease; Parkinson’s disease; Alzheimer’s disease; Friedreich’s ataxia; Huntington’s disease; Lewy body dementia; dementia; immunosenescence; inflammaging
(This special issue belongs to the Section Clinical Neurology)
Clinical Updates on Anesthesia and Perioperative Medicine
edited by Béla Fülesdi and
submission deadline 20 Mar 2027 | Viewed by 382 | Submission Open
Keywords: anesthesia; perioperative complications; residual neuromuscular block; postoperative pulmonary complications; intensive care unit acquired weakness; intensive care medicine; airway management; patient safety
(This special issue belongs to the Section Anesthesiology)
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