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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Epidemiology Associated Risks and Intervention Strategies of Childhood Obesity
edited by , and Eduardo Guzmán-Muñoz
submission deadline 28 Aug 2026 | Viewed by 615 | Submission Open
Keywords: childhood obesity; overweight; eating disorders; nutritional programs; psychological interventions; physical activity exercise; sport; physical well-being; mental well-being; quality of life
(This special issue belongs to the Section Clinical Pediatrics)
Drug-Related Problems: Clinical Pharmacy and Safety of Pharmacotherapy submission deadline 30 Aug 2026 | 3 articles | Viewed by 5709 | Submission Open
Keywords: adverse drug reaction; drug-related problems; drug formulation technology; safety of pharmacotherapy; clinical pharmacy; pharmaceutical care; pharmacology
(This special issue belongs to the Section Pharmacology)
Clinical Updates in Trauma and Emergency Medicine
edited by Yong-Soo Cho and Hyun Ho Ryu
submission deadline 31 Aug 2026 | 5 articles | Viewed by 8711 | Submission Open
Keywords: emergency medicine; epidemiology; cardiovascular disease
(This special issue belongs to the Section Emergency Medicine)
Infectious Diseases and Host Responses: Clinical, Immunological, and Outcome-Orientated Perspectives
edited by
submission deadline 31 Aug 2026 | 3 articles | Viewed by 3112 | Submission Open
Keywords: microbiology; infection; resistance; epidemiology; microbiome; prevention; therapy
(This special issue belongs to the Section Infectious Diseases)
Chronic Obstructive Pulmonary Disease (COPD): Treatment and Management—Second Edition
edited by and Alfredo Antonio Chetta
submission deadline 31 Aug 2026 | 3 articles | Viewed by 1886 | Submission Open
Keywords: chronic obstructive pulmonary disease (COPD); treatable traits; precision medicine; COPD comorbidities; COPD mortality
(This special issue belongs to the Section Respiratory Medicine)
The New Perspective in Transcatheter Aortic Valve Implantation (TAVI)
edited by Salvatore Giordano, Arturo Giordano and Nicola Corcione
submission deadline 31 Aug 2026 | 3 articles | Viewed by 1801 | Submission Open
Keywords: transcatheter aortic valve implantation (TAVI); structural heart intervention; aortic stenosis; valve technology and durability; imaging and procedural optimization
(This special issue belongs to the Section Cardiovascular Medicine)
Interventional Cardiology: Emerging Insights into Therapeutic Advancements
edited by Dong-Hyeok Kim
submission deadline 31 Aug 2026 | 1 articles | Viewed by 1681 | Submission Open
Keywords: conduction system pacing (CSP); left bundle branch area pacing (LBBAP); interventional electrophysiology; advanced pacing strategies; heart failure device therapy
(This special issue belongs to the Section Cardiology)
Advances in Anticoagulant and Antiplatelet Therapy for Coronary Artery Disease: 2nd Edition
edited by
submission deadline 31 Aug 2026 | 1 articles | Viewed by 1292 | Submission Open
Keywords: platelet; anticoagulant therapy; antiplatelet therapy; coronary artery disease (CAD); atrial fibrillation (AF); thromboembolic events; myocardial ischemic; bleeding events; aspirin; clopidogrel; cardiovascular and cerebrovascular diseases; diagnosis and treatment; percutaneous coronary intervention; acute coronary syndrome
(This special issue belongs to the Section Cardiology)
Recent Advances and Future Perspectives on Spinal Surgeries
edited by
submission deadline 31 Aug 2026 | 1 articles | Viewed by 890 | Submission Open
Keywords: minimally invasive spine procedures; robotic-assisted spine surgery; image-guided navigation; spinal implants and biomaterials; artificial intelligence in spinal care; regenerative spine therapies; clinical outcomes in spine surgery; future trends in spinal interventions
(This special issue belongs to the Section Orthopedics)
Clinical Management of Type 1 Diabetes: 2nd Edition
edited by Carmen Quirós
submission deadline 31 Aug 2026 | Viewed by 284 | Submission Open
Keywords: type 1 diabetes; continuous glucose monitoring; hybrid closed loop; hypoglycemia; physical activity; new onset type 1 diabetes; pre-stage 3 type 1 diabetes; smart insulin pens
(This special issue belongs to the Section Endocrinology & Metabolism)
Management of Complex Orthopaedic Trauma and Bone Infection
edited by
submission deadline 31 Aug 2026 | Viewed by 280 | Submission Open
Keywords: complex orthopaedic trauma; fracture-related infection (FRI); bone and implant-associated infection; chronic osteomyelitis; post-traumatic infection; biofilm-associated infection; advanced fracture management; limb reconstruction; nonunion and delayed union; multidisciplinary trauma care
(This special issue belongs to the Section Orthopedics)
Molecular Mechanisms and Therapeutic Strategies in Pediatric Immune Dysregulation
edited by Rita Consolini and
submission deadline 31 Aug 2026 | Viewed by 176 | Submission Open
Keywords: immune dysregulation; autoimmunity; inborn errors of immunity; targeted therapies; immunomodulatory treatments; genetics; gene therapy; hematopoietic stem cell transplantation
(This special issue belongs to the Section Immunology & Rheumatology)
Advances in Maxillofacial Surgery—Historical and Future Perspectives and Controversies submission deadline 1 Sep 2026 | 8 articles | Viewed by 10992 | Submission Open
Keywords: oral oncology; facial skeleton; oral cavity; surgical approaches; head and neck; parotid tumors; jaw cysts and tumors; bone healing; patient-specific solutions; surgery planning; artificial intelligence; soft tissues; cancers and tumors of the oral cavity; microsurgery perspectives; open surgery; endoscopic surgery; trauma surgery; facial traumatology; bone and soft tissues healing after trauma; jaw deformities; orthognathic surgery today and tomorrow
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Rehabilitation Strategies for Chronic Musculoskeletal Pain
edited by Ana Isabel de la Llave Rincon and
submission deadline 1 Sep 2026 | 2 articles | Viewed by 2489 | Submission Open
Keywords: pain; musculoskeletal; rehabilitation; treatment; classification
(This special issue belongs to the Section Clinical Rehabilitation)
Optimizing the Surgical Journey: From Abdominal Operation to Recovery
edited by and Carlo Bergamini
submission deadline 1 Sep 2026 | 2 articles | Viewed by 1317 | Submission Open
Keywords: surgical complications; comanagement; comorbidities; elective surgical procedure; emergency surgery procedure; multidisciplinary approach; hospitalist
(This special issue belongs to the Section General Surgery)
Current Practice and Future Directions in Hemodialysis and Peritoneal Dialysis
edited by
submission deadline 1 Sep 2026 | Viewed by 325 | Submission Open
Keywords: kidney replacement therapy; hemodialysis; peritoneal dialysis; dialysis nursing; continuous renal replacement therapy; incremental dialysis; decremental dialysis
(This special issue belongs to the Section Nephrology & Urology)
Clinical Advances of Retinal and Vitreous Diseases: Current Status and Prospect
edited by Lorenzo De Angelis, Francesco Barca and Stanislao Rizzo
submission deadline 5 Sep 2026 | 6 articles | Viewed by 4994 | Submission Open
Keywords: vitreoretinal surgery; retinal multimodal imaging; gene therapy; retinal diseases; age-related macular degeneration; vascular retinal disease; imaging technologies in ophthalmology
(This special issue belongs to the Section Ophthalmology)
New Technologies and Translational Approach for an Early Diagnosis of Bipolar Spectrum and Hyperactive and Novelty Seeking Profiles
edited by , Serdar Dursun and
submission deadline 10 Sep 2026 | 5 articles | Viewed by 17451 | Submission Open
Keywords: psychiatry; mental health; bipolar disorders; mood; biomarkers; new technology; BD
(This special issue belongs to the Section Mental Health)
Challenges and Opportunities in Prenatal Diagnosis submission deadline 10 Sep 2026 | 10 articles | Viewed by 16004 | Submission Open
Keywords: prenatal diagnosis; genetic testing; fetal imaging; fetal therapy; personalized prenatal medicine
(This special issue belongs to the Section Obstetrics & Gynecology)
Non-Invasive Respiratory Support: Current Insights and Future Directions
edited by Giovanni Misseri and
submission deadline 10 Sep 2026 | 4 articles | Viewed by 11991 | Submission Open
Keywords: respiratory failure; high-flow nasal cannula (HFNC); noninvasive ventilation (NIV); noninvasive positive pressure ventilation (NPPV); hypoxia; perioperative care; weaning; ICU; respiratory care; respiratory physiology; pneumology; home-care ventilation; artificial intelligence; personalized medicine
(This special issue belongs to the Section Respiratory Medicine)
Clinical Diagnosis and Management of Corneal Diseases
edited by , and Panagiota Ntonti
submission deadline 10 Sep 2026 | 4 articles | Viewed by 5426 | Submission Open
Keywords: corneal imaging; corneal disease diagnosis; corneal therapeutics; regenerative corneal treatments; artificial intelligence in corneal diagnostics; corneal cross-linking; lamellar keratoplasty
(This special issue belongs to the Section Ophthalmology)
Clinical Diagnosis and Therapeutic Approaches for Acute and Chronic Coronary Syndromes
edited by Rocco Antonio Montone
submission deadline 10 Sep 2026 | 2 articles | Viewed by 4653 | Submission Open
Keywords: coronary artery disease; clinical diagnosis; therapeutic approaches; atherosclerosis; risk factors; percutaneous cor-onary intervention; acute coronary syndrome; MINOCA; INOCA
(This special issue belongs to the Section Cardiology)
Updates on Physiotherapy in Pain Management
edited by and George Gioftsos
submission deadline 10 Sep 2026 | 3 articles | Viewed by 3210 | Submission Open
Keywords: pain management; physiotherapy; chronic pain; rehabilitation; pain assessment; patient outcomes; musculoskeletal; central sensitization; pain sensitivity; analgesia; pain modulation; exercise therapy; pain education; telerehabilitation; health-related quality of life; pain coping strategies
(This special issue belongs to the Section Clinical Rehabilitation)
Prevention, Diagnosis, and Clinical Treatment of Corneal Diseases
edited by Rossella Anna Maria Colabelli-Gisoldi and
submission deadline 10 Sep 2026 | 4 articles | Viewed by 2965 | Submission Open
Keywords: dry eye disease; cornea transplant; stem cell therapy; corneal imaging; cornea disease; deep anterior lamellar keratoplasty; descemet stripping automated endothelial keratoplasty; descemet membrane endothelial keratoplasty; keratoconus; eye bank
(This special issue belongs to the Section Ophthalmology)
Robotic Urologic Surgery: Clinical Applications and Advances
edited by Athanasios N. Kostakopoulos and
submission deadline 10 Sep 2026 | 2 articles | Viewed by 1402 | Submission Open
Keywords: robotic surgery; robotic urology; advances in robotics; urologic surgery; minimally invasive urologic surgery; robotic partial nephrectomy; robotic radical prostatectomy
(This special issue belongs to the Section Nephrology & Urology)
Knee Surgery: Clinical Treatment and Management
edited by Nikolai Ramadanov
submission deadline 10 Sep 2026 | 2 articles | Viewed by 754 | Submission Open
Keywords: knee surgery; sports knee injuries; ligament reconstruction; meniscal surgery; cartilage repair; knee osteotomy; knee arthroplasty; clinical outcomes; surgical techniques
(This special issue belongs to the Section Orthopedics)
Clinical Management and Rehabilitation of Sports Injuries and Musculoskeletal Disorders
edited by , and Francesco Cuozzo
submission deadline 10 Sep 2026 | 1 articles | Viewed by 461 | Submission Open
Keywords: sports injuries; musculoskeletal disorders; injury prevention; sports medicine; rehabilitation
(This special issue belongs to the Section Sports Medicine)
Management of Inguinal Hernia Surgery, Chronic Pain and Technological Future submission deadline 10 Sep 2026 | Viewed by 311 | Submission Open
Keywords: inguinal hernia; chronic pain; radical cure; technology; medical and surgery future
(This special issue belongs to the Section General Surgery)
Cardiac Intensive Care Units: Clinical Advances and Future Challenges
edited by Luca Baldetti
submission deadline 10 Sep 2026 | Viewed by 306 | Submission Open
Keywords: cardiac intensive care; heart failure; cardiogenic shock; mechanical circulatory support; invasive hemodynamic monitoring; acute cardiac care; shock; myocardial infarction
(This special issue belongs to the Section Cardiology)
Improving Short- and Long-Term Neurological Outcomes in Perioperative Anesthesia and Critical Care submission deadline 10 Sep 2026 | Viewed by 302 | Submission Open
Keywords: perioperative brain injury; neuroprotection; multimodal neuromonitoring; delirium; neurocritical care; cerebral perfusion and oxygenation; precision anesthesia; artificial intelligence in critical care
(This special issue belongs to the Section Intensive Care)
Photodynamic Therapy and Optical Diagnostics in Cancer: Clinical Advances, Translational Innovation and Future Prospects
edited by
submission deadline 10 Sep 2026 | Viewed by 298 | Submission Open
Keywords: photodynamic therapy; optical diagnostics; photodiagnosis; optical imaging; cancer treatment; photosensitisers; light-based therapy; PDT dosimetry; fluorescence imaging; optical coherence tomography; raman spectroscopy; elastic scattering spectroscopy; hyperspectral imaging; image-guided surgery; optical biopsy; minimally invasive oncology; combination cancer therapies; translational photomedicine; clinical outcomes; precision oncology
(This special issue belongs to the Section Oncology)
Clinical Practice of Imaging in Coronary Interventional Therapy
edited by Nobuaki Suzuki
submission deadline 10 Sep 2026 | Viewed by 241 | Submission Open
Keywords: coronary artery disease; cardiac imaging; intravascular ultrasound; near-infrared spectroscopy; optical coherence tomography; fractional flow reserve computed tomography
(This special issue belongs to the Section Cardiology)
Cardiac Amyloidosis and Amyloid Cardiomyopathy: Advances in Cardiovascular Care
edited by Marcus Anthony Urey
submission deadline 10 Sep 2026 | Viewed by 212 | Submission Open
Keywords: amyloidosis; diagnostics; disease progression; restrictive cardiomyopathy; degraders; silencers; stabilizers
(This special issue belongs to the Section Cardiology)
Recent Advances in Lymphedema
edited by Shinsuke Akita
submission deadline 10 Sep 2026 | Viewed by 206 | Submission Open
Keywords: lymphedema; lymphaticovenular anastomosis (LVA); vascularized lymph node transfer (VLNT); immediate lymphatic reconstruction; indocyanine green lymphography; ultrasonography; bioimpedance analysis; imaging and staging of lymphedema; fibrosis and inflammation; patient-reported outcome measures
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Gynecologic Robotic Surgery: Evolution, Current Status and Future Directions
edited by Youn-Jee Chung
submission deadline 13 Sep 2026 | 2 articles | Viewed by 1346 | Submission Open
Keywords: laparoscopy; robot surgery; minimally invasive surgery; gynecology; endometriosis; myoma; adenomyosis
(This special issue belongs to the Section Obstetrics & Gynecology)
Musculoskeletal Spine Disorders: Clinical Management, Rehabilitation Strategies, and Technological Innovations
edited by , and Calogero Foti
submission deadline 14 Sep 2026 | 1 articles | Viewed by 971 | Submission Open
Keywords: spine disorders; rehabilitation; physical exercise; low back pain; scoliosis; adolescent idiopathic scoliosis
(This special issue belongs to the Section Orthopedics)
Biomarkers and Diagnostics in Neurological Diseases
edited by Maria Ioanna Stefanou
submission deadline 15 Sep 2026 | 10 articles | Viewed by 19332 | Submission Open
Keywords: biomarkers; neurological diseases; diagnosis; lipoprotein(a); neurofilament protein; tau peptide; neuroimaging
(This special issue belongs to the Section Clinical Neurology)
Advances in Diagnosis and Treatment of Endometriosis
edited by and
submission deadline 15 Sep 2026 | 6 articles | Viewed by 10264 | Submission Open
Keywords: endometriosis; adenomyosis; diagnosis; classification; therapy; progesterone
(This special issue belongs to the Section Obstetrics & Gynecology)
Thyroid Disease: Updates from Diagnosis to Treatment: 2nd Edition submission deadline 15 Sep 2026 | 7 articles | Viewed by 8832 | Submission Open
Keywords: autoimmune thyroid diseases; thyroiditis; thyroid cancers; PET/CT; hyperthyroidism
(This special issue belongs to the Section Endocrinology & Metabolism)
Current Challenges in Clinical Dentistry: 3rd Edition
edited by and
submission deadline 15 Sep 2026 | 2 articles | Viewed by 4416 | Submission Open
Keywords: artificial intelligence; clinical dentistry; cutting-edge device and technology; dental material; challenging hypothesis; preventive dentistry; sleep medicine; digital dentistry; smart dentistry; stomatognathic function
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Latest Advances in Thoracic Surgery: 2nd Edition
edited by
submission deadline 15 Sep 2026 | 2 articles | Viewed by 3915 | Submission Open
Keywords: lung cancer; surgical oncology; robotic surgery; thoracic surgery; lung diseases; minimally invasive surgery
(This special issue belongs to the Section Respiratory Medicine)
Plastic and Reconstructive Surgery: Clinical Advances and Future Opportunities
edited by Rami S Kantar
submission deadline 15 Sep 2026 | 4 articles | Viewed by 3486 | Submission Open
Keywords: plastic surgery; reconstructive surgery; cleft lips; palates; post-traumatic reconstruction; facial transplantation; craniofacial surgery; cleft surgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Clinical Advances in Obesity and Bariatric Surgery—2nd Edition
edited by Valentin Mocanu and Jerry Dang
submission deadline 15 Sep 2026 | 3 articles | Viewed by 2981 | Submission Open
Keywords: obesity; bariatric surgery; metabolic surgery; anti-obesity medications; obesity treatment
(This special issue belongs to the Section Endocrinology & Metabolism)
Risk Prediction in Mechanical Circulatory Support (MCS) and Cardiac Transplantation
edited by
submission deadline 15 Sep 2026 | 3 articles | Viewed by 2750 | Submission Open
Keywords: advanced heart failure; mechanical circulatory support (MCS); cardiac transplantation; heart transplantation; risk prediction
(This special issue belongs to the Section Cardiology)
Clinical Management and Challenges of Sepsis and Septic Shock submission deadline 15 Sep 2026 | 2 articles | Viewed by 1469 | Submission Open
Keywords: sepsis; septic shock; hemodynamic management; biomarkers; cardiovascular dysfunction; point-of-care ultrasound; precision medicine; emergency medicine; critical care
(This special issue belongs to the Section Intensive Care)
Advances in Pancreatic Cancer: Diagnosis and Therapy
edited by Eleonora Lai, and
submission deadline 15 Sep 2026 | 1 articles | Viewed by 1072 | Submission Open
Keywords: pancreatic cancer diagnosis; endoscopic ultrasound; neoadjuvant chemotherapy; surgical resection; targeted therapy; immunotherapy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Advances in Cardiac Resynchronization Treatment: 2nd Edition
edited by , Konstantinos A. Gatzoulis, Konstantinos Aronis and
submission deadline 15 Sep 2026 | 1 articles | Viewed by 891 | Submission Open
Keywords: conduction system; risk stratification; resynchronization; cardiac pacing; sudden cardiac death
(This special issue belongs to the Section Cardiology)
Esophageal and Upper Gastrointestinal Surgery: Clinical Advances and Practical Updates
edited by and Peter Grimminger
submission deadline 15 Sep 2026 | 1 articles | Viewed by 862 | Submission Open
Keywords: esophageal cancer; gastric cancer; upper GI surgery; surgical oncology; benign upper GI surgery; surgical innovation; surgical outcomes; surgical guidelines; robotic surgery; minimally invasive surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Cancers: Clinical Radiation Therapy
edited by Julianne M. Pollard-Larkin
submission deadline 15 Sep 2026 | 1 articles | Viewed by 859 | Submission Open
Keywords: reirradiation; tissue tolerance; image registration; treatment planning; dose accumulation
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Sports Injuries: Emerging Trends in Risk Mitigation, Management and Recovery
edited by and Jose Asian-Clemente
submission deadline 15 Sep 2026 | 1 articles | Viewed by 818 | Submission Open
Keywords: injury prevention; rehabilitation; muscle; return-to-sport; surgery; therapy; testing; regenerative medicine; ultrasound; MRI; sports medicine
(This special issue belongs to the Section Sports Medicine)
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