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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Contemporary Coronary Intervention: Innovation, Evidence, and Patient-Centred Outcomes
edited by Kevin Liou
submission deadline 20 Aug 2026 | 1 articles | Viewed by 887 | Submission Open
Keywords: percutaneous coronary interventions; coronary imaging; coronary physiology; precision medicine; CHIP PCI; stent-less technologies; clinical outcomes; pharmacotherapy in PCI; biomarkers; artificial intelligence in PCI; sustainability in PCI
(This special issue belongs to the Section Cardiology)
Current Trends and Progress in Eating Disorders and Obesity Management
edited by Davide Gravina, and
submission deadline 20 Aug 2026 | 1 articles | Viewed by 770 | Submission Open
Keywords: eating disorders; anorexia nervosa; bulimia nervosa; binge-eating disorder; ARFID; obesity; neuromodulation; biomarkers; gut microbiome; pharmacological interventions; incretin receptor agonists; GLP-1; metreleptin; psychedelics
(This special issue belongs to the Section Mental Health)
Spine Surgery: Clinical Advances and Future Directions—2nd Edition
edited by Eun-Sang Kim and
submission deadline 20 Aug 2026 | 1 articles | Viewed by 741 | Submission Open
Keywords: spine surgery; back pain; endoscopic spine surgery; cage implantation; neck pain
(This special issue belongs to the Section Clinical Neurology)
Physiotherapy: Multidisciplinary Interventions and Digital Health submission deadline 20 Aug 2026 | 1 articles | Viewed by 694 | Submission Open
Keywords: physiotherapy; rehabilitation; physical medicine; digital health; telemedicine; virtual reality; augmented reality; artifi-cial intelligence; robotic rehabilitation; wearable sensors; VR for educative goals; musculoskeletal, neurological, cognitive, pediatric, pulmonary, cardiac and gyneco-obstetric disorders; fibromyalgia syndrome; chronic pain; older adults
(This special issue belongs to the Section Clinical Rehabilitation)
Clinical Advances in Hearing Loss: Diagnosis, Treatment, and Management
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 686 | Submission Open
Keywords: hearing loss; deafness; bone conduction implants; middle ear implants; cochlear implants; myringoplasty; tympanoplasty; stapedotomy; ossicular chain reconstruction; imaging; audiological diagnostic
(This special issue belongs to the Section Otolaryngology)
Retinal Diseases: Recent Advances in Diagnosis and Treatment—2nd Edition
edited by Dario Giorgio and Dario Pasquale Mucciolo
submission deadline 20 Aug 2026 | 1 articles | Viewed by 663 | Submission Open
Keywords: retinal diseases; retinal degeneration; macular degeneration; OCT; retinal imaging
(This special issue belongs to the Section Ophthalmology)
Anterior Segment Disorders
edited by Itay Lavy and
submission deadline 20 Aug 2026 | 1 articles | Viewed by 657 | Submission Open
Keywords: anterior segment disorders; corneal disease; cataract surgery; ocular surface disease; surgical outcomes; surgical techniques; artificial intelligence in diagnosis; diagnostic imaging; pharmacological and surgical interventions; refractive errors; anterior uveitis; keratitis; corneal ectasia; quality of life
(This special issue belongs to the Section Ophthalmology)
Exploring Female Infertility: Advances, Challenges, and Emerging Solutions
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 597 | Submission Open
Keywords: infertility; female infertility; in vitro fertilization; PCOS; assisted reproductive technology
(This special issue belongs to the Section Obstetrics & Gynecology)
Hepatobiliary–Pancreatic Surgery in the Era of Interventional Radiology
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 596 | Submission Open
Keywords: hepato-biliary–pancreatic surgery; interventional radiology; percutaneous biliary drainage; percutaneous pancre-atic drainage; portal vein embolization; tumor ablation; minimally invasive surgery; cryoablation; thermoablation
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Breaking the Barrier: Early Detection of Pancreatic Ductal Adenocarcinoma (PDAC) submission deadline 20 Aug 2026 | 1 articles | Viewed by 571 | Submission Open
Keywords: pancreatic ductal adenocarcinoma (PDAC); pancreatic cancer; IPMN; PDAC screening; early PDAC detection; PDAC biomarkers; CT; NMR
(This special issue belongs to the Section Oncology)
Carotid Artery Disease: Current Hurdles and Future Perspectives
edited by Andrej Udelnow
submission deadline 20 Aug 2026 | 1 articles | Viewed by 561 | Submission Open
Keywords: carotid artery disease; carotid stenosis; endovascular technique; CEUS; elastography; high resolution CTA; atherosclerotic diseases; inflammatory diseases
(This special issue belongs to the Section Vascular Medicine)
Maxillofacial Surgery in the Modern Era: Surgical Advances and Clinical Innovation submission deadline 20 Aug 2026 | 1 articles | Viewed by 498 | Submission Open
Keywords: maxillofacial surgery; oral surgery; craniofacial surgery; plastic surgery; bone
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
New Insights into Gastrointestinal Surgery: Advances in Techniques and Treatment Approaches
edited by Gabriella Teresa Capolupo
submission deadline 20 Aug 2026 | Viewed by 487 | Submission Open
Keywords: gastroenterology; gastrointestinal surgery; colorectal surgery; robotic surgery; technologies; minimally invasive surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Updates on Reproductive Endocrinology in Children and Adolescents submission deadline 20 Aug 2026 | Viewed by 418 | Submission Open
Keywords: reproductive endocrinology; adolescents; male hypogonadism; female hypogonadism; reproductive metabolism; PCOS; POF; receptor abnormalities; menstrual cycle; transgender health; CAH; ovaries; gonads; hormones; sex development; amenorrhea; estrogen resistance; androgen resistance; teen pregnancy; oncology; preservation of fertility
(This special issue belongs to the Section Clinical Pediatrics)
Current Concepts and Technological Innovations in Hepato-Pancreato-Biliary Surgery and Transplantation
edited by Michele Finotti and Francesco D’Amico
submission deadline 20 Aug 2026 | Viewed by 366 | Submission Open
Keywords: hepato-pancreato-biliary surgery; hepato-pancreato-biliary transplantation; pancreatic cancer; hepatobiliary cancer; vascular reconstruction; minimally invasive in hepato-pancreato-biliary surgery; robotic techniques; organ-preservation strategies
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances in Orthopedic Infections: 2nd Edition
edited by
submission deadline 20 Aug 2026 | Viewed by 363 | Submission Open
Keywords: orthopedic surgery; orthopedic infections; periprosthetic joint infection; surgical site infection; infection management
(This special issue belongs to the Section Orthopedics)
Precision Neuroimaging in Mental and Behavioral Health Research
edited by Thomas Vanicek and Arkadiusz Komorowski
submission deadline 20 Aug 2026 | Viewed by 359 | Submission Open
Keywords: psychiatry; neuroimaging; addiction; substance use disorders (SUD); attention deficit hyperactivity disorder (ADHD); imaging genomics; imaging transcriptomics
(This special issue belongs to the Section Mental Health)
State of the Art in Bladder Cancer: Diagnostics and Treatment Strategies
edited by
submission deadline 20 Aug 2026 | Viewed by 354 | Submission Open
Keywords: bladder cancer; photodynamic diagnosis (PDD); bladder-sparing strategies; robotic-assisted surgery; single-port robotic cystectomy; older patients; immunotherapy; intravesical therapy; bladder preservation; minimally invasive urology; advanced bladder cancer; diagnostic innovation
(This special issue belongs to the Section Nephrology & Urology)
Optimizing Rehabilitation in Kidney Disease
edited by Henry H. L. Wu and Rajkumar Chinnadurai
submission deadline 20 Aug 2026 | Viewed by 332 | Submission Open
Keywords: chronic kidney disease; renal rehabilitation; exercise intervention; nutrition; multidisciplinary; frailty; physical conditioning
(This special issue belongs to the Section Clinical Rehabilitation)
Advances in Pulmonary Embolism Therapeutics
edited by
submission deadline 20 Aug 2026 | Viewed by 329 | Submission Open
Keywords: acute pulmonary embolism; chronic pulmonary embolism; chronic thromboembolic disease; chronic thromboem-bolic pulmonary hypertension; catheter-directed therapy; pulmonary endarterectomy; balloon pulmonary angio-plasty
(This special issue belongs to the Section Vascular Medicine)
Integrated Ozone Therapy and Physical Rehabilitation for Musculoskeletal Disorders: A Comprehensive Approach submission deadline 20 Aug 2026 | Viewed by 329 | Submission Open
Keywords: ozone therapy; physical rehabilitation; musculoskeletal disorders; integrative medicine; rehabilitation therapy; regenerative medicine; clinical outcomes
(This special issue belongs to the Section Clinical Rehabilitation)
Clinical Advances in Adult Deformities and Spinal Disorders: Surgical Treatment and Pre- and Post-Operative Re-Habilitation
edited by
submission deadline 20 Aug 2026 | Viewed by 329 | Submission Open
Keywords: scoliosis; spine; kyphosis; degenerative spine; spine surgery
(This special issue belongs to the Section Orthopedics)
The Liver–Kidney Axis in Metabolic Diseases: Biomarkers and Clinical Implications
edited by
submission deadline 20 Aug 2026 | Viewed by 324 | Submission Open
Keywords: liver; kidney; cross-organ crosstalk; mechanisms; biomarkers; metabolic diseases; clinical implications
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Novel Approaches in Obsessive–Compulsive and Related Spectrum Disorders
edited by and Andrea D. Guastello
submission deadline 20 Aug 2026 | Viewed by 318 | Submission Open
Keywords: OCD; misophonia; hoarding; tic disorders; assessment; treatment
(This special issue belongs to the Section Mental Health)
Updates on Embolization and Embolotherapy for Benign Prostatic Hyperplasia and Men’s Health
edited by Sandeep L. Bagla, Ari J. Isaacson and Abin Sajan
submission deadline 20 Aug 2026 | Viewed by 315 | Submission Open
Keywords: benign prostatic hyperplasia; prostatic artery embolization; men’s health; lower urinary tract symptoms; embolization therapy; radiation safety; prostate cancer and radiotherapy
(This special issue belongs to the Section Nephrology & Urology)
Bleeding and Thrombotic Complications in Patients with Premalignant Hematologic Conditions: Diagnostic and Therapeutic Challenges
edited by Vasiliki Gkalea and Despina Fotiou
submission deadline 20 Aug 2026 | Viewed by 314 | Submission Open
Keywords: bleeding; thrombosis; hematologic malignancies; premalignant hematologic conditions; clonal hematopoiesis of indeterminate potential (CHIP); clonal cytopenias of undetermined significance (CCUS); monoclonal gammopathy of undetermined significance (MGUS); monoclonal B-cell lymphocytosis (MBL); monoclonal gammopathy of thrombotic significance (MGTS); VITT-like MGTS
(This special issue belongs to the Section Hematology)
Clinical Advances and Perspectives in Neuro-Oncology
edited by Mariko Sato and
submission deadline 20 Aug 2026 | Viewed by 307 | Submission Open
Keywords: neuro-oncology; diagnosis; treatment; minimally invasive surgery; skull base surgery; brain tumor; radiosurgery; neuro endoscopy
(This special issue belongs to the Section Clinical Neurology)
Current Trends and Innovations in Coronary Artery Disease and Myocardial Ischemia: Second Edition
edited by
submission deadline 20 Aug 2026 | Viewed by 298 | Submission Open
Keywords: coronary artery disease; fractional flow reserve; invasive coronary angiography; cardiac CT; cardiac MRI
(This special issue belongs to the Section Cardiovascular Medicine)
Advances in Diagnosis, Monitoring, and Treatment of Myocardial Infarction
edited by
submission deadline 20 Aug 2026 | Viewed by 290 | Submission Open
Keywords: myocardial infarction (MI); occlusion myocardial infarction (OMI); myocardial infarction with non-obstructive coronary arteries (MINOCA); diagnosis; monitoring; treatment
(This special issue belongs to the Section Cardiovascular Medicine)
Personalised and Precision Pharmacotherapy: Data-Driven Therapeutic Optimisation in Real-World Clinical Practice submission deadline 20 Aug 2026 | Viewed by 287 | Submission Open
Keywords: precision pharmacotherapy; personalised medicine ; pharmacokinetics and pharmacodynamics ; therapeutic drug ; monitoring real-world evidence ; multimorbidity ; medication appropriateness ; model-informed precision dosing; does individualisation; clinical decision support
(This special issue belongs to the Section Pharmacology)
Managing Chronic Kidney Disease: Current Practices and Future Perspectives
edited by Maria L. Gonzalez-Suarez
submission deadline 20 Aug 2026 | Viewed by 287 | Submission Open
Keywords: chronic kidney disease; diabetic kidney disease; kidney failure; guideline-directed therapies; SLGT 2 inhibitors; GLP1 receptor agonists
(This special issue belongs to the Section Nephrology & Urology)
From Histology to Clinical Immunology: Integrated Diagnosis in Oral and Maxillofacial Diseases
edited by Fabiana Nicita
submission deadline 20 Aug 2026 | Viewed by 278 | Submission Open
Keywords: clinical immunology; histology; immunopathology; immune-mediated oral disease; biomarkers
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Approaches of Intracranial Aneurysm and Subarachnoid Hemorrhage
edited by Sylvia Bele
submission deadline 20 Aug 2026 | Viewed by 275 | Submission Open
Keywords: aSAH; clipping or coiling; extracranial complications; cerebral vasospasm; ICU treatment
(This special issue belongs to the Section Clinical Neurology)
Clinical Advances in Diagnosis and Treatment of Metastatic Spinal Tumor
edited by
submission deadline 20 Aug 2026 | Viewed by 267 | Submission Open
Keywords: metastatic spinal tumors; spine surgery; bone metastasis; imaging diagnosis; minimally invasive surgery; decompression surgery; fixation surgery; emergency surgery; prognosis prediction; elderly patients; nutrition; mental health
(This special issue belongs to the Section Oncology)
Recent Clinical Perspectives on Chronic Kidney Disease
edited by Luca Visconti
submission deadline 20 Aug 2026 | Viewed by 267 | Submission Open
Keywords: chronic kidney disease; nephrology; hemodialysis; renal impairment; renal replacement therapy; new therapeutic approaches in CKD; clinical trials; renal complications
(This special issue belongs to the Section Nephrology & Urology)
Targeting Extravalvular Burden Associated with Valvular Heart Disease
edited by
submission deadline 20 Aug 2026 | Viewed by 263 | Submission Open
Keywords: valvular heart disease; systemic disorder; extravalvular burden; valve dysfunction; valve intervention; multimodality imaging
(This special issue belongs to the Section Cardiology)
Therapeutic Advances and Emerging Treatments in Inflammatory Bowel Disease
edited by
submission deadline 20 Aug 2026 | Viewed by 258 | Submission Open
Keywords: inflammatory bowel disease; therapeutic advances emerging treatments; biologics and small molecules; precision medicine in IBD; pharmacokinetic model
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Revisional and Conversion Bariatric Surgery: Safety and Outcomes
edited by Jerry Dang and Thomas H. Shin
submission deadline 20 Aug 2026 | Viewed by 256 | Submission Open
Keywords: revisional bariatric surgery; conversion surgery; weight recurrence; surgical outcomes; sleeve gastrectomy; roux-en-y gastric bypass; post-bariatric complications; GERD
(This special issue belongs to the Section General Surgery)
Recent Advances in Hypercholesterolemia
edited by Ana Catarina Alves
submission deadline 20 Aug 2026 | Viewed by 250 | Submission Open
Keywords: hypercholesterolemia; cardiovascular risk; molecular diagnostics; variants of uncertain significance (VUS); functional characterisation; precision medicine; lipid-lowering therapy
(This special issue belongs to the Section Endocrinology & Metabolism)
Pancreatic Cancer: Novel Strategies of Diagnosis and Treatment submission deadline 21 Aug 2026 | 3 articles | Viewed by 6637 | Submission Open
Keywords: pancreatic cancer; chronic pancreatitis; pancreatic intraepithelial neoplasia; gastroenterology; clinical innovative diagnostic; clinical treatment strategies
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Outcomes of Glaucoma Surgery: Visual Acuity, Effectiveness and Quality of Life submission deadline 21 Aug 2026 | 5 articles | Viewed by 3362 | Submission Open
Keywords: glaucoma surgery; visual acuity; intraocular pressure; surgical outcomes; trabeculectomy; microinvasive glaucoma surgery; postoperative complications; functional vision
(This special issue belongs to the Section Ophthalmology)
Personalized Modern Oncological Strategies for Breast Cancer Treatment
edited by Vlad Alexandru Gata, Maximilian Muntean and
submission deadline 22 Aug 2026 | 5 articles | Viewed by 3941 | Submission Open
Keywords: breast cancer; targeted and immune therapies; predictive biomarkers; surgical de-escalation; MRI of the breast; breast reconstruction
(This special issue belongs to the Section General Surgery)
Advances in Plastic and Reconstructive and Aesthetic Surgery of Face, Breast and Body
edited by
submission deadline 24 Aug 2026 | 6 articles | Viewed by 19809 | Submission Open
Keywords: reconstructive surgery; academic plastic surgery; research; social media in plastic surgery; breast surgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Advancements in Cardiomyopathies: Diagnosis, Treatment and Management—2nd Edition submission deadline 24 Aug 2026 | 5 articles | Viewed by 11155 | Submission Open
Keywords: cardiomyopathies; multimodality imaging; cardiac magnetic resonance; genetic testing; cardiogenetics; genetic cardiovascular disease; rare cardiovascular diseases; risk stratification; genotype–phenotype correlations; rare variant interpretation; arrhythmias
(This special issue belongs to the Section Cardiology)
Clinical Advances in Head and Neck Cancer Diagnostics and Treatment
edited by and Alice L. Tang
submission deadline 24 Aug 2026 | 1 articles | Viewed by 1498 | Submission Open
Keywords: head and neck; reconstruction; free flap; surgical margin; biomarker; human papillomavirus (HPV); extranodal extension; immunotherapy; virtual surgical planning
(This special issue belongs to the Section Otolaryngology)
Interventional and Surgical Treatment of Acute and Chronic Pancreatitis
edited by Chirag Desai
submission deadline 25 Aug 2026 | 6 articles | Viewed by 21916 | Submission Open
Keywords: pancreatitis treatment; endoscopic treatment; pancreatic surgery; Whipple; distal pancreatectomy; islet cell auto trans-plant; total pancreatectomy; TPIAT; laparoscopic treatment of pancreatitis; robotic surgery for pancreatitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Alcohol-Related Liver Disease: Diagnosis, Treatment, and Management submission deadline 25 Aug 2026 | 5 articles | Viewed by 15658 | Submission Open
Keywords: alcohol-related liver disease; gut–liver axis; hepatic fibrosis; liver cirrhosis; micro-RNA; inflammatory pathways; liver transplantation; steatohepatitis; fecal microbiota transplantation in liver cirrhosis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Periodontal Diseases and Systemic Health: Pathogenesis, Prevention and Management
edited by
submission deadline 25 Aug 2026 | 8 articles | Viewed by 12544 | Submission Open
Keywords: periodontitis; dental implants; systemic inflammation; diabetes and periodontal disease; cardiovascular implications; pregnancy and oral health; host immune responses; preventive dentistry; implant-prosthetic rehabilitation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Advances in the Management of Cardiac Amyloidosis and Hypertrophic Cardiomyopathy
edited by Ahmed Abuzaid
submission deadline 25 Aug 2026 | 4 articles | Viewed by 10052 | Submission Open
Keywords: cardiac amyloidosis; hypertrophic cardiomyopathy; left ventricular hypertrophy; non-invasive cardiac imaging; heart failure; clinical manifestations
(This special issue belongs to the Section Cardiology)
New Insights into Cardiorenal Metabolic Syndrome
edited by
submission deadline 25 Aug 2026 | 4 articles | Viewed by 9448 | Submission Open
Keywords: cardiorenal medicine; diabetes; chronic renal failure; heart failure; cardiorenal syndrome; nephrocardiology
(This special issue belongs to the Section Cardiovascular Medicine)
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