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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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From Clinical Diagnosis to Effective Treatment of Cardiomyopathy

edited by

Sanjay Sivalokanathan

and

Łukasz A. Małek

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1905 | Submission Open

Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathy; non-ischemic cardiomyopathy; cardiac MRI; PET/CT; PET/MRI; cardiac imaging; sudden cardiac death

(This special issue belongs to the Section Cardiology)

Optimizing Blood Management in Perioperative Cardiac Care: A Multidisciplinary Approach

edited by

Paul Abraham

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1720 | Submission Open

Keywords: perioperative cardiac care; patient blood management; cardiac surgery; blood transfusion; transfusion thresholds; bleeding management; hemostatic therapy; anticoagulation management; point‑of‑care coagulation testing

(This special issue belongs to the Section Cardiology)

Advances in Maternal–Fetal Medicine

edited by

C. Andrew Combs

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1683 | Submission Open

Keywords: maternal–fetal medicine; obstetric ultrasound; preterm birth; preeclampsia; pregnancy complications; artificial intelligence

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Updates on Acromegaly

edited by

Marek Bolanowski

, Jowita Halupczok-Żyła, Aleksandra Gilis-Januszewska and Przemysław Witek

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1676 | Submission Open

Keywords: acromegaly; GH; IGH-1; growth hormone-secreting pituitary adenoma; pituitary adenoma

(This special issue belongs to the Section Endocrinology & Metabolism)

Recent Advances in Refractive Surgery and Intraocular Lens Implantation

edited by Antonio Leccisotti

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1630 | Submission Open

Keywords: refractive surgery; intraocular lens implantation; keratectomy; cornea; ocular surgery; optical coherence tomography; laser surgery; KLEx (keratorefractive lenticule extraction); femtolasik

(This special issue belongs to the Section Ophthalmology)

New Insights into Orthodontic Treatment

edited by Federico Brugnami and Simonetta Meuli

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1578 | Submission Open

Keywords: digital orthodontics; clear aligners; artificial intelligence; digital superimpositions; cone beam computed tomography; growing patients; periodontal patients; maxillofacial surgery; long-term stability; prediction of orthodontic movements

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

New Developments and Challenges in Assisted Reproductive Technology

edited by

Shuqin Wei

and

Justin Tan

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1480 | Submission Open

Keywords: assisted reproductive technology; in vitro fertilization; clinical protocols and innovations; embryo selection and evaluation; ethnicity and reproductive outcomes; live birth; cryopreservation and fertility preservation; maternal and offspring health outcomes; global perspectives in reproductive medicine

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Applications and Surgical Integration of Advanced Ophthalmic Imaging

edited by Katarzyna Nowomiejska

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1442 | Submission Open

Keywords: ophthalmic imaging; retina; intraoperative OCT; personalized treatment; clinical applications

(This special issue belongs to the Section Ophthalmology)

Coronary Artery Disease in the Era of Artificial Intelligence: Clinical Insights and Therapeutic Challenges

edited by Konstantinos Mourouzis

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1424 | Submission Open

Keywords: coronary artery disease; myocardial ischemia; coronary imaging; revascularization; cardiometabolic risk; biomarkers; artificial intelligence; endothelial dysfunction; inflammation; arterial stiffness; antiplatelet therapy; heart failure; intraoperative graft verification

(This special issue belongs to the Section Cardiovascular Medicine)

Diagnosis and Clinical Management in Hematologic Oncology

edited by Sunil Lakhwani and José María Raya-Sánchez

submission deadline 20 Aug 2026 | 3 articles | Viewed by 1324 | Submission Open

Keywords: hematologic malignancies; lymphoma; multiple myeloma; acute leukemia; myeloproliferative neoplasms; molecular diagnostics; targeted therapy; immunotherapy; prognostic biomarkers; clinical management

(This special issue belongs to the Section Hematology)

Maxillofacial Surgery in the Modern Era: Surgical Advances and Clinical Innovation

edited by

Jeremie Oliver Piña

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1255 | Submission Open

Keywords: maxillofacial surgery; oral surgery; craniofacial surgery; plastic surgery; bone

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Heart Failure and Transplant Cardiology: Latest Advances and Prospects

edited by Monika Budnik

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1253 | Submission Open

Keywords: heart failure; heart transplantation; bridge to transplant; mechanical circulatory support; cardiomyopathies

(This special issue belongs to the Section Cardiology)

Clinical Update on Prenatal Diagnosis and Maternal Fetal Medicine

edited by Gianluca Campobasso

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1199 | Submission Open

Keywords: fetal medicine; malformations; obstetric; prenatal diagnosis; artificial intelligence

(This special issue belongs to the Section Obstetrics & Gynecology)

Spine Neurosurgery: Latest Advances and Prospects

edited by Jun Jae Shin, Bong Ju Moon and Chang Kyu Lee

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1074 | Submission Open

Keywords: cervical spine; cervical myelopathy; ossification of the posterior longitudinal ligament (OPLL); endoscopic spine surgery; minimally invasive spine surgery; spinal deformity

(This special issue belongs to the Section Clinical Neurology)

Future-Proof Care for Patients with Kidney Stones

edited by

Stijn Roemeling

and Oliver Wiseman

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1059 | Submission Open

Keywords: effectiveness; resilience; prevention; care pathways; urolithiasis; kidney stones; PCNL; URS; ESWL; quality of life

(This special issue belongs to the Section Nephrology & Urology)

Endoscopic Imaging for the Diagnosis and Treatment of Gastrointestinal Diseases

edited by Mariana Jinga and

Daniel Vasile Balaban

submission deadline 20 Aug 2026 | 1 articles | Viewed by 968 | Submission Open

Keywords: endoscopy; endoscopic ultrasound; endoscopic retrograde cholangiopancreatography; artificial intelligence; diagnosis; therapy; decision making; endobiopsy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Innovations and Challenges in the Burden and Rehabilitation of Musculoskeletal Disorders

edited by

Carla Sílvia Fernandes

and

Marta Campos Ferreira

submission deadline 20 Aug 2026 | 1 articles | Viewed by 959 | Submission Open

Keywords: musculoskeletal diseases; rehabilitation; physical therapy modalities; telemedicine; mobile applications; health information technology; patient-centered care; quality of life; health care innovation

(This special issue belongs to the Section Clinical Rehabilitation)

Contemporary Coronary Intervention: Innovation, Evidence, and Patient-Centred Outcomes

edited by Kevin Liou

submission deadline 20 Aug 2026 | 1 articles | Viewed by 913 | Submission Open

Keywords: percutaneous coronary interventions; coronary imaging; coronary physiology; precision medicine; CHIP PCI; stent-less technologies; clinical outcomes; pharmacotherapy in PCI; biomarkers; artificial intelligence in PCI; sustainability in PCI

(This special issue belongs to the Section Cardiology)

Current Trends and Progress in Eating Disorders and Obesity Management

edited by Davide Gravina,

Claudia Carmassi

and

Maria Livanou

submission deadline 20 Aug 2026 | 1 articles | Viewed by 806 | Submission Open

Keywords: eating disorders; anorexia nervosa; bulimia nervosa; binge-eating disorder; ARFID; obesity; neuromodulation; biomarkers; gut microbiome; pharmacological interventions; incretin receptor agonists; GLP-1; metreleptin; psychedelics

(This special issue belongs to the Section Mental Health)

Spine Surgery: Clinical Advances and Future Directions—2nd Edition

edited by Eun-Sang Kim and

Seung-Kook Kim

submission deadline 20 Aug 2026 | 1 articles | Viewed by 761 | Submission Open

Keywords: spine surgery; back pain; endoscopic spine surgery; cage implantation; neck pain

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in Hearing Loss: Diagnosis, Treatment, and Management

edited by

Wojciech Gawȩcki

submission deadline 20 Aug 2026 | 1 articles | Viewed by 736 | Submission Open

Keywords: hearing loss; deafness; bone conduction implants; middle ear implants; cochlear implants; myringoplasty; tympanoplasty; stapedotomy; ossicular chain reconstruction; imaging; audiological diagnostic

(This special issue belongs to the Section Otolaryngology)

Retinal Diseases: Recent Advances in Diagnosis and Treatment—2nd Edition

edited by Dario Giorgio and Dario Pasquale Mucciolo

submission deadline 20 Aug 2026 | 1 articles | Viewed by 712 | Submission Open

Keywords: retinal diseases; retinal degeneration; macular degeneration; OCT; retinal imaging

(This special issue belongs to the Section Ophthalmology)

Anterior Segment Disorders

edited by Itay Lavy and

Nir Erdinest

submission deadline 20 Aug 2026 | 1 articles | Viewed by 689 | Submission Open

Keywords: anterior segment disorders; corneal disease; cataract surgery; ocular surface disease; surgical outcomes; surgical techniques; artificial intelligence in diagnosis; diagnostic imaging; pharmacological and surgical interventions; refractive errors; anterior uveitis; keratitis; corneal ectasia; quality of life

(This special issue belongs to the Section Ophthalmology)

Breaking the Barrier: Early Detection of Pancreatic Ductal Adenocarcinoma (PDAC)

edited by

Ewa Małecka-Wojciesko

submission deadline 20 Aug 2026 | 1 articles | Viewed by 665 | Submission Open

Keywords: pancreatic ductal adenocarcinoma (PDAC); pancreatic cancer; IPMN; PDAC screening; early PDAC detection; PDAC biomarkers; CT; NMR

(This special issue belongs to the Section Oncology)

Hepatobiliary–Pancreatic Surgery in the Era of Interventional Radiology

edited by

Dimitrios Giannis

submission deadline 20 Aug 2026 | 1 articles | Viewed by 659 | Submission Open

Keywords: hepato-biliary–pancreatic surgery; interventional radiology; percutaneous biliary drainage; percutaneous pancre-atic drainage; portal vein embolization; tumor ablation; minimally invasive surgery; cryoablation; thermoablation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Exploring Female Infertility: Advances, Challenges, and Emerging Solutions

edited by

Claire Ann Jones

submission deadline 20 Aug 2026 | 1 articles | Viewed by 630 | Submission Open

Keywords: infertility; female infertility; in vitro fertilization; PCOS; assisted reproductive technology

(This special issue belongs to the Section Obstetrics & Gynecology)

Carotid Artery Disease: Current Hurdles and Future Perspectives

edited by Andrej Udelnow

submission deadline 20 Aug 2026 | 1 articles | Viewed by 621 | Submission Open

Keywords: carotid artery disease; carotid stenosis; endovascular technique; CEUS; elastography; high resolution CTA; atherosclerotic diseases; inflammatory diseases

(This special issue belongs to the Section Vascular Medicine)

New Insights into Gastrointestinal Surgery: Advances in Techniques and Treatment Approaches

edited by Gabriella Teresa Capolupo

submission deadline 20 Aug 2026 | Viewed by 499 | Submission Open

Keywords: gastroenterology; gastrointestinal surgery; colorectal surgery; robotic surgery; technologies; minimally invasive surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Updates on Reproductive Endocrinology in Children and Adolescents

edited by

Charikleia Stefanaki

submission deadline 20 Aug 2026 | Viewed by 428 | Submission Open

Keywords: reproductive endocrinology; adolescents; male hypogonadism; female hypogonadism; reproductive metabolism; PCOS; POF; receptor abnormalities; menstrual cycle; transgender health; CAH; ovaries; gonads; hormones; sex development; amenorrhea; estrogen resistance; androgen resistance; teen pregnancy; oncology; preservation of fertility

(This special issue belongs to the Section Clinical Pediatrics)

Precision Neuroimaging in Mental and Behavioral Health Research

edited by Thomas Vanicek and Arkadiusz Komorowski

submission deadline 20 Aug 2026 | Viewed by 370 | Submission Open

Keywords: psychiatry; neuroimaging; addiction; substance use disorders (SUD); attention deficit hyperactivity disorder (ADHD); imaging genomics; imaging transcriptomics

(This special issue belongs to the Section Mental Health)

Clinical Advances in Orthopedic Infections: 2nd Edition

edited by

Hyonmin Choe

submission deadline 20 Aug 2026 | Viewed by 369 | Submission Open

Keywords: orthopedic surgery; orthopedic infections; periprosthetic joint infection; surgical site infection; infection management

(This special issue belongs to the Section Orthopedics)

State of the Art in Bladder Cancer: Diagnostics and Treatment Strategies

edited by

Angelo Porreca

submission deadline 20 Aug 2026 | Viewed by 362 | Submission Open

Keywords: bladder cancer; photodynamic diagnosis (PDD); bladder-sparing strategies; robotic-assisted surgery; single-port robotic cystectomy; older patients; immunotherapy; intravesical therapy; bladder preservation; minimally invasive urology; advanced bladder cancer; diagnostic innovation

(This special issue belongs to the Section Nephrology & Urology)

Novel Approaches in Obsessive–Compulsive and Related Spectrum Disorders

edited by

Joshua M. Nadeau

and Andrea D. Guastello

submission deadline 20 Aug 2026 | Viewed by 343 | Submission Open

Keywords: OCD; misophonia; hoarding; tic disorders; assessment; treatment

(This special issue belongs to the Section Mental Health)

Optimizing Rehabilitation in Kidney Disease

edited by Henry H. L. Wu and Rajkumar Chinnadurai

submission deadline 20 Aug 2026 | Viewed by 339 | Submission Open

Keywords: chronic kidney disease; renal rehabilitation; exercise intervention; nutrition; multidisciplinary; frailty; physical conditioning

(This special issue belongs to the Section Clinical Rehabilitation)

Clinical Advances in Adult Deformities and Spinal Disorders: Surgical Treatment and Pre- and Post-Operative Re-Habilitation

edited by

Laura Scaramuzzo

submission deadline 20 Aug 2026 | Viewed by 339 | Submission Open

Keywords: scoliosis; spine; kyphosis; degenerative spine; spine surgery

(This special issue belongs to the Section Orthopedics)

Integrated Ozone Therapy and Physical Rehabilitation for Musculoskeletal Disorders: A Comprehensive Approach

edited by

Giovanni Ricevuti

and

Salvatore Chirumbolo

submission deadline 20 Aug 2026 | Viewed by 336 | Submission Open

Keywords: ozone therapy; physical rehabilitation; musculoskeletal disorders; integrative medicine; rehabilitation therapy; regenerative medicine; clinical outcomes

(This special issue belongs to the Section Clinical Rehabilitation)

Updates on Embolization and Embolotherapy for Benign Prostatic Hyperplasia and Men’s Health

edited by Sandeep L. Bagla, Ari J. Isaacson and Abin Sajan

submission deadline 20 Aug 2026 | Viewed by 329 | Submission Open

Keywords: benign prostatic hyperplasia; prostatic artery embolization; men’s health; lower urinary tract symptoms; embolization therapy; radiation safety; prostate cancer and radiotherapy

(This special issue belongs to the Section Nephrology & Urology)

Clinical Advances and Perspectives in Neuro-Oncology

edited by Mariko Sato and

John Ross Crawford

submission deadline 20 Aug 2026 | Viewed by 326 | Submission Open

Keywords: neuro-oncology; diagnosis; treatment; minimally invasive surgery; skull base surgery; brain tumor; radiosurgery; neuro endoscopy

(This special issue belongs to the Section Clinical Neurology)

Advances in Diagnosis, Monitoring, and Treatment of Myocardial Infarction

edited by

Rita Pavasini

submission deadline 20 Aug 2026 | 1 articles | Viewed by 325 | Submission Open

Keywords: myocardial infarction (MI); occlusion myocardial infarction (OMI); myocardial infarction with non-obstructive coronary arteries (MINOCA); diagnosis; monitoring; treatment

(This special issue belongs to the Section Cardiovascular Medicine)

Bleeding and Thrombotic Complications in Patients with Premalignant Hematologic Conditions: Diagnostic and Therapeutic Challenges

edited by Vasiliki Gkalea and Despina Fotiou

submission deadline 20 Aug 2026 | Viewed by 321 | Submission Open

Keywords: bleeding; thrombosis; hematologic malignancies; premalignant hematologic conditions; clonal hematopoiesis of indeterminate potential (CHIP); clonal cytopenias of undetermined significance (CCUS); monoclonal gammopathy of undetermined significance (MGUS); monoclonal B-cell lymphocytosis (MBL); monoclonal gammopathy of thrombotic significance (MGTS); VITT-like MGTS

(This special issue belongs to the Section Hematology)

Personalised and Precision Pharmacotherapy: Data-Driven Therapeutic Optimisation in Real-World Clinical Practice

edited by

Fátima Roque

and

Ignatios Ioakeim-Skoufa

submission deadline 20 Aug 2026 | Viewed by 303 | Submission Open

Keywords: precision pharmacotherapy; personalised medicine ; pharmacokinetics and pharmacodynamics ; therapeutic drug ; monitoring real-world evidence ; multimorbidity ; medication appropriateness ; model-informed precision dosing; does individualisation; clinical decision support

(This special issue belongs to the Section Pharmacology)

Managing Chronic Kidney Disease: Current Practices and Future Perspectives

edited by Maria L. Gonzalez-Suarez

submission deadline 20 Aug 2026 | Viewed by 290 | Submission Open

Keywords: chronic kidney disease; diabetic kidney disease; kidney failure; guideline-directed therapies; SLGT 2 inhibitors; GLP1 receptor agonists

(This special issue belongs to the Section Nephrology & Urology)

Clinical Approaches of Intracranial Aneurysm and Subarachnoid Hemorrhage

edited by Sylvia Bele

submission deadline 20 Aug 2026 | Viewed by 287 | Submission Open

Keywords: aSAH; clipping or coiling; extracranial complications; cerebral vasospasm; ICU treatment

(This special issue belongs to the Section Clinical Neurology)

From Histology to Clinical Immunology: Integrated Diagnosis in Oral and Maxillofacial Diseases

edited by Fabiana Nicita

submission deadline 20 Aug 2026 | Viewed by 281 | Submission Open

Keywords: clinical immunology; histology; immunopathology; immune-mediated oral disease; biomarkers

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Advances in Diagnosis and Treatment of Metastatic Spinal Tumor

edited by

Takeo Furuya

submission deadline 20 Aug 2026 | Viewed by 279 | Submission Open

Keywords: metastatic spinal tumors; spine surgery; bone metastasis; imaging diagnosis; minimally invasive surgery; decompression surgery; fixation surgery; emergency surgery; prognosis prediction; elderly patients; nutrition; mental health

(This special issue belongs to the Section Oncology)

Recent Advances in Hypercholesterolemia

edited by Ana Catarina Alves

submission deadline 20 Aug 2026 | Viewed by 273 | Submission Open

Keywords: hypercholesterolemia; cardiovascular risk; molecular diagnostics; variants of uncertain significance (VUS); functional characterisation; precision medicine; lipid-lowering therapy

(This special issue belongs to the Section Endocrinology & Metabolism)

Recent Clinical Perspectives on Chronic Kidney Disease

edited by Luca Visconti

submission deadline 20 Aug 2026 | Viewed by 272 | Submission Open

Keywords: chronic kidney disease; nephrology; hemodialysis; renal impairment; renal replacement therapy; new therapeutic approaches in CKD; clinical trials; renal complications

(This special issue belongs to the Section Nephrology & Urology)

Therapeutic Advances and Emerging Treatments in Inflammatory Bowel Disease

edited by

Laura Ramos

submission deadline 20 Aug 2026 | Viewed by 272 | Submission Open

Keywords: inflammatory bowel disease; therapeutic advances emerging treatments; biologics and small molecules; precision medicine in IBD; pharmacokinetic model

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Targeting Extravalvular Burden Associated with Valvular Heart Disease

edited by

Giovanni La Canna

submission deadline 20 Aug 2026 | Viewed by 269 | Submission Open

Keywords: valvular heart disease; systemic disorder; extravalvular burden; valve dysfunction; valve intervention; multimodality imaging

(This special issue belongs to the Section Cardiology)

Pancreatic Cancer: Novel Strategies of Diagnosis and Treatment

edited by

Camelia Cristina Diaconu

and

Gina Gheorghe

submission deadline 21 Aug 2026 | 3 articles | Viewed by 6739 | Submission Open

Keywords: pancreatic cancer; chronic pancreatitis; pancreatic intraepithelial neoplasia; gastroenterology; clinical innovative diagnostic; clinical treatment strategies

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Displaying special issue 51-100 on page 2 of 30.

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