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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancements in Anterior Cruciate Ligament Injury: From Diagnosis to the Return-to-Sports: 2nd Edition

edited by Alexandre Hardy and Nicolas Bouguennec

submission deadline 28 May 2026 | 4 articles | Viewed by 3160 | Submission Open

Keywords: anterior cruciate ligament reconstruction (ACLR); timing of ACLR; ramp lesion; meniscal lesion; lateral extra-articular procedure

(This special issue belongs to the Section Sports Medicine)

Clinical Updates in Heart Transplantation

edited by

Giacomo Bianchi

submission deadline 28 May 2026 | 2 articles | Viewed by 1783 | Submission Open

Keywords: heart transplantation; ex vivo heart preservation; immunosuppression; xenotransplantation; pre-clinical models; dilated cardiomyopathy; amyloidosis; congenital heart disease

(This special issue belongs to the Section Cardiology)

Innovations in Thoracic Surgery and Disease Management: Integrating Genomics, Technology, and Multidisciplinary Care

edited by

Marco Scarci

and

Savvas Lampridis

submission deadline 28 May 2026 | 1 articles | Viewed by 541 | Submission Open

Keywords: thoracic surgery; thoracic disease; genomic medicine; artificial intelligence; advanced imaging; multidisciplinary care; minimally invasive surgery; robotic surgery; precision medicine

(This special issue belongs to the Section Respiratory Medicine)

Cerebrovascular Disease: Symptoms, Diagnosis and Current Treatment—Second Edition

edited by Alba Scerrati and Giorgio Mantovani

submission deadline 28 May 2026 | 2 articles | Viewed by 530 | Submission Open

Keywords: ischemic stroke; cerebral aneurysms; cerebral vascular malformation; cerebral venous disease; cerebral venous thrombosis

(This special issue belongs to the Section Clinical Neurology)

Novel Treatments for Vestibular Migraine

edited by

Teru Kamogashira

submission deadline 28 May 2026 | Viewed by 303 | Submission Open

Keywords: neuromodulation therapy; sympathetic nerve stimulation; CGRP-targeted therapy; dietary interventions; elimination diets; ketogenic diet; low-glycemic index diet; nutritional supplements; pathophysiology of vestibular migraine; clinical adoption of VM therapies

(This special issue belongs to the Section Otolaryngology)

Challenges in the Diagnosis and Treatment of Glaucoma

edited by

Abdelaziz Abdelaal

submission deadline 28 May 2026 | Viewed by 257 | Submission Open

Keywords: glaucoma diagnosis; glaucoma progression; glaucoma biomarkers; intraocular pressure (IOP) management; corneal hysteresis; machine learning in glaucoma detection; neuroprotection in glaucoma; surgery and laser therapy

(This special issue belongs to the Section Ophthalmology)

Spine Surgery Innovations: Treatments and Technologies

edited by

Marco D. Burkhard

and Tomoyuki Asada

submission deadline 29 May 2026 | Viewed by 435 | Submission Open

Keywords: AI; robotics; navigation; muscle preservation; minimally invasive surgery; motion preservation; alignment targets; implant materials; bone growth factors; custom-made implants

(This special issue belongs to the Section Orthopedics)

Pediatric Hearing Loss: Advances in Early Detection, Intervention and Family-Centered Care

edited by

Daniel Holzinger

and

Johannes Hofer

submission deadline 30 May 2026 | Viewed by 82 | Submission Open

Keywords: pediatric hearing loss; early intervention; early identification of language and communication disorders; develop-mental language disorders; predictors of outcomes; newborn hearing screening; pediatric audiology

(This special issue belongs to the Section Otolaryngology)

Clinical Perspectives on Women’s Reproductive Health: Challenges and Management Strategies

edited by

Seok Kyo Seo

submission deadline 31 May 2026 | 8 articles | Viewed by 17591 | Submission Open

Keywords: endometriosis; ovarian endometrioma; polycystic ovary syndrome; reproductive health; cervical; postmenopausal women; hormone replacement therapy; sarcopenia

(This special issue belongs to the Section Obstetrics & Gynecology)

Understanding Syncope: Multidisciplinary Approaches to Diagnosis and Management

edited by

Isabel Rocha

and Sérgio Laranjo

submission deadline 31 May 2026 | 4 articles | Viewed by 5503 | Submission Open

Keywords: syncope; diagnostic strategies; prognostication; treatment options; quality of life; wearable devices; artificial intelligence; autonomic dysfunction; orthostatic hypotension; POTS (postural orthostatic tachycardia syndrome)

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Updates on Prosthodontics

edited by

Rubén Agustín Panadero

and Carla Fons-Badal

submission deadline 31 May 2026 | 3 articles | Viewed by 3235 | Submission Open

Keywords: dental prosthesis; dental implants; gingival aesthetics; gingival treatment; dental aesthetics; dental ceramics; BOPT; surgical periodontal treatment

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Cardiovascular Magnetic Resonance Imaging: Precise Diagnosis and Therapeutic Guidance

edited by Radu Andy Sascau and

Carina Gabriela Ureche

submission deadline 31 May 2026 | 2 articles | Viewed by 1618 | Submission Open

Keywords: cardiac magnetic resonance; cardiomyopathy; tissue characterization; stress perfusion; 4D flow; heart failure; ischemic heart disease; multi-modality imaging; valvular heart disease; T1 mapping; T2 mapping; myocarditis

(This special issue belongs to the Section Cardiovascular Medicine)

Advances in Male Infertility: Diagnosis, Management and ART Integration

edited by Despoina Mavrogianni and Sofoklis Stavros

submission deadline 31 May 2026 | Viewed by 1234 | Submission Open

Keywords: male infertility; assisted reproductive technologies (ART); intracytoplasmic sperm injection (ICSI); genetic testing; hormonal profiling; seminal biomarkers; sperm retrieval techniques; sperm selection; stem cell therapy; gene editing; reproductive endo-crinology; early pregnancy; implantation failure; recurrent miscarriage

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Early Prevention and Diagnosis of Atherosclerosis: From Clinical Progression to Patient Management

edited by

Anna Kabłak-Ziembicka

submission deadline 31 May 2026 | 1 articles | Viewed by 733 | Submission Open

Keywords: atherosclerosis; atherothrombotic molecular pathways; cardiovascular risk; monitoring of goals; pharmacological and non-pharmacological prevention; carotid and peripheral interventions

(This special issue belongs to the Section Cardiovascular Medicine)

New Insights into Hepato-Biliary Diseases: Translating Science into Practice

edited by

Elisa Ceccherini

and

Antonella Cecchettini

submission deadline 31 May 2026 | Viewed by 334 | Submission Open

Keywords: hepato-biliary diseases; biomarkers; drug discovery; liver organoids and microfluidics; pathogenesis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Personalized Management of Abdominal Surgery and Complications

edited by Ioannis Mantzoros and

Orestis Ioannidis

submission deadline 31 May 2026 | Viewed by 127 | Submission Open

Keywords: personalized medicine; abdominal surgery; complications; emergency; innovative surgery

(This special issue belongs to the Section General Surgery)

Clinical Advances and Contemporary Applications of Echocardiography

edited by

Attila Nemes

submission deadline 31 May 2026 | Viewed by 94 | Submission Open

Keywords: echocardiography; speckle-tracking; three-dimensional; Doppler; cardiac; valve; vasculature

(This special issue belongs to the Section Cardiovascular Medicine)

Current Advances and Future Challenges in Heart Transplantation

edited by

Norihide Fukushima

submission deadline 31 May 2026 | Viewed by 79 | Submission Open

Keywords: heart transplantation; indication; surgical techniques; preoperative care; immunosuppressive regimens; mechanical circulatory support; donor assessment and management; cardiac donation after circulatory death; ex vivo machine perfusion; normothermic regional perfusion; cardiac xenotransplantation

(This special issue belongs to the Section Cardiology)

Applications of Artificial Intelligence (AI) in Surgery

edited by

Syed Ali Haider

and

Antonio Jorge Forte

submission deadline 31 May 2026 | Viewed by 60 | Submission Open

Keywords: artificial intelligence; machine learning; surgical robotics; computer vision; predictive analytics; surgical decision support; perioperative care; surgical outcomes; digital surgery

(This special issue belongs to the Section General Surgery)

Advances in the Management of Cancer Pain

edited by Wojciech Leppert

submission deadline 31 May 2026 | Viewed by 56 | Submission Open

Keywords: analgesia; analgesics; cancer patients; chronic pain; pain in cancer patients; pain assessment; non-opioids; opioid analgesics; adjuvant analgesics; non-pharmacology methods of pain management

(This special issue belongs to the Section Epidemiology & Public Health)

Aortic Surgery—Back to the Roots and Looking to the Future

edited by Ezin Deniz and

Aron-Frederik Popov

submission deadline 31 May 2026 | Viewed by 8 | Submission Open

Keywords: aortic surgery; hybrid and endovascular innovations; perioperative management; cerebral and organ protection; biomaterials; translational cardiovascular research; imaging in aortic disease; long-term outcomes; cardiovascular surgery

(This special issue belongs to the Section Cardiovascular Medicine)

Diagnosis and Treatment of Pediatric Endocrine Disorders—Focus on Rare Conditions

edited by Sophia Sakka

submission deadline 1 Jun 2026 | Viewed by 1143 | Submission Open

Keywords: pediatric endocrinology; diabetes mellitus in children; bone metabolism disorders; clinical diagnosis; therapeutic strategies; skeletal dysplasias; rare endocrine conditions; pediatric type 1 diabetes; rickets management; genetic conditions; pediatric hormone therapy; achondroplasia

(This special issue belongs to the Section Endocrinology & Metabolism)

Orthodontics: State of the Art and Prospects

edited by Beatriz Tarazona-Álvarez and

Natalia Zamora-Martínez

submission deadline 5 Jun 2026 | 1 articles | Viewed by 1791 | Submission Open

Keywords: digital orthodontics; clear aligners; 3D printing; accelerated orthodontics; digital treatment plan; nanotechnology

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Latest Research on Male Infertility

edited by

Manesh Kumar Panner Selvam

submission deadline 5 Jun 2026 | 1 articles | Viewed by 916 | Submission Open

Keywords: testis; sperm; seminal plasma; spermatogenesis; fertilization; omics; proteomics; oxidative stress; sperm DNA fragmentation; varicocele; male infertility; testicular cancer; infertility management; ART

(This special issue belongs to the Section Reproductive Medicine & Andrology)

New Insights on Pharmacologic and Non-Pharmacologic Therapy of Advanced Heart Failure

edited by

Michael Dandel

submission deadline 5 Jun 2026 | Viewed by 66 | Submission Open

Keywords: advanced heart failure (AHF); mechanical circulatory support systems; heart transplantation (HTx); immunosuppression; cardiac allograft rejections

(This special issue belongs to the Section Cardiology)

Sjogren’s Syndrome: Clinical Advances and Insights

edited by David A. Isenberg

submission deadline 7 Jun 2026 | 1 articles | Viewed by 167 | Submission Open

Keywords: xerostomia; xerophthalmia; non-Hodgkins lymphoma; autoimmune rheumatic diseases; Sjogren’ s syndrome

(This special issue belongs to the Section Immunology & Rheumatology)

Clinical Research and Personalized Medicine in Inflammatory Bowel Disease

edited by

Alfredo Papa

and Loris Riccardo Lopetuso

submission deadline 10 Jun 2026 | 4 articles | Viewed by 5213 | Submission Open

Keywords: inflammatory bowel disease (IBD); personalized medicine; precision medicine; Crohn’ s disease; ulcerative colitis; targeted therapy; artificial intelligence

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Perspectives of Vascular and Endovascular Surgeries

edited by

Adrian Vasile Muresan

Emil Marian Arbănași

and

Eliza Russu

submission deadline 10 Jun 2026 | 2 articles | Viewed by 2370 | Submission Open

Keywords: vascular surgery; varicose veins; abdominal aortic aneurysms; carotid disease; peripheral arterial disease

(This special issue belongs to the Section Vascular Medicine)

Regional Anesthesia and Pain Management: Mastering Clinical Art for Optimal Patient Satisfaction

edited by

Min Suk Chae

submission deadline 10 Jun 2026 | 2 articles | Viewed by 2054 | Submission Open

Keywords: regional anesthesia; pain management; ultrasound-guided nerve blocks; fascial plane blocks; multimodal analgesia; postoperative analgesia; chronic pain management; opioid-sparing strategies; non-opioid analgesics; patient satisfaction; anesthesia techniques; perioperative care; pain interventions; nerve block techniques; clinical outcomes

(This special issue belongs to the Section Anesthesiology)

Cardiovascular Health: Advances in Prevention, Treatment and Innovative Therapies

edited by

Ibadete Bytyçi

submission deadline 10 Jun 2026 | Viewed by 1275 | Submission Open

Keywords: atherosclerosis; dyslipidemia; cardiac risk factors; premature ASCVD; left atrium function; atrial fibrillation; coronary imaging

(This special issue belongs to the Section Cardiovascular Medicine)

Surgical Management of Maxillofacial Fractures and Reconstruction of Facial Deformities

edited by

Gian Marco Prucher

Andrea Cassoni

and Francesco Arcuri

submission deadline 10 Jun 2026 | 2 articles | Viewed by 901 | Submission Open

Keywords: head and neck reconstruction; facial fractures; minimally invasive treatments; facial reconstruction; bioengineering in head and neck disorders; CAD/CAM in maxillo facial trauma and deformities

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Diabetes Mellitus and Emerging Health Challenges: A Multidisciplinary Perspective

edited by Katarzyna A. Majewska and

Agnieszka Zawada

submission deadline 10 Jun 2026 | 2 articles | Viewed by 780 | Submission Open

Keywords: diabetes mellitus; type 1 diabetes; type 2 diabetes; diabetic complications; prediabetes; diabetes treatment; autoimmune diabetes

(This special issue belongs to the Section Endocrinology & Metabolism)

Exploring Cardiomyopathy: Comprehensive Guide to Causes, Symptoms and Care

edited by

Keiichi Hirono

submission deadline 10 Jun 2026 | Viewed by 307 | Submission Open

Keywords: cardiomyopathy; heart failure; genetics; hypertrophic cardiomyopathy; dilated cardiomyopathy; left ventricular noncompaction; pediatric cardiomyopathies; cardiac imaging

(This special issue belongs to the Section Cardiology)

Clinical Outcomes Improvement and Perioperative Management of Surgical Patients: 3rd Edition

edited by

Dimitrios E. Magouliotis

and

Dimitris Zacharoulis

submission deadline 10 Jun 2026 | 2 articles | Viewed by 274 | Submission Open

Keywords: clinical outcomes; surgery; quality; quality of life; quality improvement; postoperative; morbidity; postoperative care

(This special issue belongs to the Section General Surgery)

Clinical and Diagnostic Strategies for Glioma Treatment

edited by Aleksandrs Krigers and Egils Valeinis

submission deadline 10 Jun 2026 | Viewed by 72 | Submission Open

Keywords: glioma; glioblastoma; astrocytoma; oligodendroglioma; IDH; neuro-oncology; neurosurgery; radiotherapy; neuropathology; diagnostics; treatment

(This special issue belongs to the Section Clinical Neurology)

Cardiac Arrest and Postcardiac Arrest Care: State of the Art and Future Directions

edited by

Jae-Hyug Woo

and Soheil Saadat

submission deadline 10 Jun 2026 | Viewed by 68 | Submission Open

Keywords: out-of-hospital cardiac arrest; cardiopulmonary resuscitation; postcardiac arrest syndrome; postcardiac arrest care; survival; neurologic outcomes

(This special issue belongs to the Section Emergency Medicine)

New Technologies for Personalized Medicine in Head and Neck Surgery

edited by

Carlos Navarro-Cuéllar

and

José Luis Cebríán-Carretero

submission deadline 10 Jun 2026 | Viewed by 59 | Submission Open

Keywords: personalized medicine; head and neck surgery; 3D printing; surgical navigation; artificial intelligence; computer-assisted surgery; regenerative medicine; precision oncology; craniofacial reconstruction; biomaterials; virtual surgical planning; genomics and proteomics; tissue engineering; functional rehabilitation

(This special issue belongs to the Section Otolaryngology)

Cardiomyopathy: Diagnosis and Therapeutic Advances

edited by Ilaria Dentamaro and Annagrazia Cecere

submission deadline 10 Jun 2026 | Viewed by 56 | Submission Open

Keywords: cardiomiopathy; cardiac magnetic resonance (CMR); advanced echocardiography; heart failure; hypertrophic cardiomyopathy

(This special issue belongs to the Section Cardiology)

Clinical Advancements in Intraocular Lens Power Calculation Methods

edited by

Christoph Martin Lwowski

and Thomas Kohnen

submission deadline 12 Jun 2026 | 2 articles | Viewed by 2279 | Submission Open

Keywords: emmetropia; IOL power calculation; effective lens position; refractive lens exchange; IOL; refractive surgery; biometry

(This special issue belongs to the Section Ophthalmology)

Systemic Sclerosis: State of the Art and Future Directions

edited by Antonino Mazzone and

Paola Maria Luigia Faggioli

submission deadline 12 Jun 2026 | Viewed by 55 | Submission Open

Keywords: systemic sclerosis; current knowledge; advanced knowledge; vasculopathy; interstitial lung disease; pulmonary arterial hypertension; perspectives; novelties

(This special issue belongs to the Section Dermatology)

Evidence-Based Clinical Management of Orthopaedic Trauma: 25 Years in Retrospect, and a Forecast of 25 Years to Come

edited by Dirk Stengel and

Paul Alfred Grützner

submission deadline 15 Jun 2026 | 5 articles | Viewed by 10557 | Submission Open

Keywords: evidence-based medicine; orthopaedic surgery; clinical trials; systematic reviews; patient outcomes; multiple trauma; artificial intelligence; injuries

(This special issue belongs to the Section Orthopedics)

Coronary Heart Disease: Causes, Diagnosis and Management

edited by

Andrea Denegri

submission deadline 15 Jun 2026 | 3 articles | Viewed by 9855 | Submission Open

Keywords: coronary heart disease; coronary revascularization; coronary artery disease; ischemic heart disease; atherosclerosis

(This special issue belongs to the Section Cardiology)

Aortic Pathologies: Aneurysm, Atherosclerosis and More

edited by Alexander Gombert and Panagiotis Doukas

submission deadline 15 Jun 2026 | 4 articles | Viewed by 8291 | Submission Open

Keywords: aorta; aortic aneurysm; thoracoabdominal aortic aneurysm; fenestrated endovascular aortic repair (FEVAR); branched endovascular aortic repair (BEVAR); spinal cord ischemia; coral reef aorta; surgery; endovascular aortic surgery

(This special issue belongs to the Section Cardiovascular Medicine)

Male Sexual and Reproductive Health: Clinical Aspects, Metabolic Profile, Environmental Factors and Lifestyle: 2nd Edition

edited by

Fernando Mazzilli

submission deadline 15 Jun 2026 | 3 articles | Viewed by 7370 | Submission Open

Keywords: male sexual dysfunction; reproductive health; erectile dysfunction; premature ejaculation; infertility; epidemiology; causes; diagnosis; treatments; environmental factors; lifestyle

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Advances in the Diagnosis and Treatment of Glaucoma

edited by

Alessio Martucci

submission deadline 15 Jun 2026 | 4 articles | Viewed by 5443 | Submission Open

Keywords: OCT; glaucoma; MIGS; neuroprotection; drug delivery systems; artificial intelligence; pharmacologic agents; per-sonalized medicine

(This special issue belongs to the Section Ophthalmology)

Scoliosis: Advances in Diagnosis and Management

edited by Michal Latalski

submission deadline 15 Jun 2026 | 3 articles | Viewed by 5297 | Submission Open

Keywords: scoliosis; adolescent idiopathic scoliosis; adult scoliosis; congenital scoliosis; neuromuscular scoliosis; diagnosis; imaging; treatment; surgery; bracing; rehabilitation; patient-reported outcomes; quality of life

(This special issue belongs to the Section Orthopedics)

Arthroplasty: Advances in Surgical Techniques and Patient Outcomes—2nd Edition

edited by Senthil Sambandam

submission deadline 15 Jun 2026 | 2 articles | Viewed by 3161 | Submission Open

Keywords: hip arthroplasty; knee arthroplasty; hip fractures; arthroplasty; osteoarthritis; knee arthroscopy; joint replacement

(This special issue belongs to the Section Orthopedics)

Emergency Surgery: Clinical Updates and New Perspectives

edited by

Bruno Cirillo

submission deadline 15 Jun 2026 | 1 articles | Viewed by 2032 | Submission Open

Keywords: emergency surgery; trauma surgery; acute abdomen; hernia emergencies; surgical decision making; perioperative care; damage control surgery; emergency management; critical care surgery; multidisciplinary approach

(This special issue belongs to the Section Emergency Medicine)

Gender Differences and Diversity in the Treatment of Gastric Cancer and Other Malignancies

edited by Claus Schildberg and Frank Meyer

submission deadline 15 Jun 2026 | 2 articles | Viewed by 1572 | Submission Open

Keywords: gastric cancer; other cancers; other treatment; gender differences; diversity; new challances

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Thoracic Surgery: Current Practice and Future Directions: 2nd Edition

edited by

Dania Nachira

submission deadline 15 Jun 2026 | 3 articles | Viewed by 1530 | Submission Open

Keywords: NSCLC; mediastinum; thymoma; esophageal disease; immunotherapy; new technologies; minimally invasive surgery; VATS; RATS

(This special issue belongs to the Section Respiratory Medicine)

Displaying special issue 1101-1150 on page 23 of 31.

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