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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Management of Patients with Heart Failure: 3rd Edition
edited by
submission deadline 20 Oct 2026 | 11 articles | Viewed by 10234 | Submission Open
Keywords: acute heart failure; chronic heart failure; treatment options; management of heart failure; lifestyle changes; diagnosis of heart failure
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Update on Thoracic Trauma
edited by
submission deadline 20 Oct 2026 | 6 articles | Viewed by 9150 | Submission Open
Keywords: flail chest; isolated sternal fractures; manubrio-sternal dislocation; pneumothorax; hemothorax; thoracic aortic injury; heart and pulmonary vessels lesion; intercostal artery injury; diaphragm rupture; thoracoabdominal hernia; chylothorax; esophageal perforation
(This special issue belongs to the Section Respiratory Medicine)
Application of Echocardiography in the Diagnosis and Management of Cardiac Diseases
edited by and
submission deadline 20 Oct 2026 | 6 articles | Viewed by 8915 | Submission Open
Keywords: echocardiography; cardiac diseases; 3D echo; stress; myocardial strain; intracardiac; subclinical cardiac disease
(This special issue belongs to the Section Cardiology)
Clinical Management of Corneal Diseases
edited by Hyeck Soo Son
submission deadline 20 Oct 2026 | 3 articles | Viewed by 8030 | Submission Open
Keywords: corneal diseases; keratoconus; corneal dystrophy; corneal ectasia; corneal transplantation; DMEK; DSAEK; kerato-prosthesis; crosslinking; ICRS; CAIRS; Bowman layer transplantation; treatment outcomes; clinical management
(This special issue belongs to the Section Ophthalmology)
Recent Developments in Hearing and Balance Disorders: 2nd Edition submission deadline 20 Oct 2026 | 4 articles | Viewed by 7711 | Submission Open
Keywords: ear; otology; audiology; hearing disorders; deafness; hearing loss; autoimmunity; ENT; inflammation; vertigo; imbalance
(This special issue belongs to the Section Otolaryngology)
Advances in Maternal Fetal Medicine
edited by and Anna Franca Cavaliere
submission deadline 20 Oct 2026 | 4 articles | Viewed by 7475 | Submission Open
Keywords: drugs use during pregnancy; fetal treatment; pregnancy complications; infectious diseases; neonatal poor adaptation syndrome
(This special issue belongs to the Section Obstetrics & Gynecology)
Novel Insights into Clinical Diagnosis and Management of Degenerative Cervical Myelopathy
edited by , Francesco Costa and Filippo Maria Polli
submission deadline 20 Oct 2026 | 4 articles | Viewed by 6344 | Submission Open
Keywords: degenerative cervical myelopathy (DCM); cervical spondylotic myelopathy (CSM); cervical spinal stenosis; cervical cord compression; MRI of the cervical spine; cervical spine surgery; physical therapy; rehabilitation; ossification of the posterior longitudinal ligament (OPLL); cervical deformity (e.g., kyphosis and lordosis); patient-reported out-comes; surgical outcome prediction
(This special issue belongs to the Section Clinical Neurology)
Pediatric Dentistry: Real-World Clinical Insights submission deadline 20 Oct 2026 | 4 articles | Viewed by 5752 | Submission Open
Keywords: pediatric dentistry; minimally invasive dentistry; new technologies; biomaterials; innovative management approaches; caries management; pulp management; dental trauma; molar incisor hypomineralization; public health services research; epidemiological research; translational research
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Recent Developments in Gynecological Endocrinology: 2nd Edition submission deadline 20 Oct 2026 | 2 articles | Viewed by 5456 | Submission Open
Keywords: amenorrhea; puberty; PCOS; premature ovarian insufficiency; endometriosis; infertility; pregnancy; hormones; menopause
(This special issue belongs to the Section Obstetrics & Gynecology)
Skin Cancer: Prevention, Diagnosis, Quality of Life and Treatment Outcomes
edited by Athanassios A. Kyrgidis and
submission deadline 20 Oct 2026 | 5 articles | Viewed by 5359 | Submission Open
Keywords: skin cancer; melanoma; squamous cell carcinoma; basal cell carcinoma; clinical biomarkers; dermoscopy; quality of life
(This special issue belongs to the Section Dermatology)
Clinical Insights and Emerging Techniques in Interventional Cardiology
edited by
submission deadline 20 Oct 2026 | 1 articles | Viewed by 5235 | Submission Open
Keywords: percutaneous coronary intervention; coronary imaging; intravascular ultrasound; IVUS; computed tomography; optical coherence tomography; OCT; chronic total occlusions; drug-coated balloons; bifurcations; calcified coronary lesions; rotational atherectomy; intravascular lithotripsy; acute coronary syndromes; chronic coronary syndromes
(This special issue belongs to the Section Cardiology)
Intrarenal Surgery for Kidney Stones and Other Kidney Diseases
edited by Razvan Multescu
submission deadline 20 Oct 2026 | 4 articles | Viewed by 5142 | Submission Open
Keywords: intrarenal surgery; flexible ureteroscopy; percutaneous nephrolithotomy (PCNL); Mini-PCNL; thulium laser; ureteral access sheaths; flexible and navigable suction (FANS); upper urinary tract urothelial tumors
(This special issue belongs to the Section Nephrology & Urology)
Heart Failure: Treatment and Clinical Perspectives
edited by Geza Halasz, Domenico Gabrielli and Francesco Grigioni
submission deadline 20 Oct 2026 | 6 articles | Viewed by 5141 | Submission Open
Keywords: heart failure; chronic heart failure; acute heart failure; treatment; cardiac imaging; diagnostics; patient outcomes; prognosis
(This special issue belongs to the Section Cardiology)
New Insights into Retinal Diseases
edited by Fabio Scarinci and Giulio Pocobelli
submission deadline 20 Oct 2026 | 5 articles | Viewed by 4717 | Submission Open
Keywords: optical coherence tomography; optical coherence tomography angiography; vitreoretinal diseases; retinal imaging analysis; biomarkers; segmentation; retinal ischemia; retinal blood flow; choroidal blood flow
(This special issue belongs to the Section Ophthalmology)
Clinical Updates in Imaging of Musculoskeletal Diseases submission deadline 20 Oct 2026 | 4 articles | Viewed by 4506 | Submission Open
Keywords: musculoskeletal imaging; ultrasound; magnetic resonance; sport imaging; rheumatology; nerve imaging
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Recent Advances in Endocrine Surgery—2nd Edition
edited by
submission deadline 20 Oct 2026 | 2 articles | Viewed by 4433 | Submission Open
Keywords: endocrine surgery; thyroid; thyroid cancer; parathyroid; parathyroidectomy; adrenal glands; disorders of hepatobiliary and gastrointestinal tract
(This special issue belongs to the Section General Surgery)
Clinical Implications of Pupil Function: Optical Quality, Visual Performance, and Neurological Biomarkers
edited by Pablo De Gracia and Héctor E. Soriano Baron
submission deadline 20 Oct 2026 | 1 articles | Viewed by 4367 | Submission Open
Keywords: pupil function; visual performance; intraocular lens (IOL) optimization; pupillometry diagnostics; neuro-ophthalmic biomarkers
(This special issue belongs to the Section Ophthalmology)
New Advances and Clinical Outcomes of Endocrinology
edited by Stefana Catalina Bilha and
submission deadline 20 Oct 2026 | 2 articles | Viewed by 4082 | Submission Open
Keywords: endocrinology; obesity; metabolic and bone disease; chronic conditions
(This special issue belongs to the Section Endocrinology & Metabolism)
Periodontology and Dental Implants: State of the Art and Future Perspectives
edited by Magda Mensi and
submission deadline 20 Oct 2026 | 2 articles | Viewed by 4047 | Submission Open
Keywords: periodontology; dental implants; regenerative dentistry; peri-implant diseases; digital dentistry; implant surface modifications; tissue engineering; oral microbiome; risk assessment; personalized treatment
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
New Challenges and Perspectives in Surgical Treatment of Spinal Deformity
edited by Jung-Hee Lee
submission deadline 20 Oct 2026 | 6 articles | Viewed by 3999 | Submission Open
Keywords: adult spinal deformity; decompensation; kyphosis; lateral lumbar interbody fusion; orthopedic surgery; osteotomy; proximal junctional kyphosis; rod fracture
(This special issue belongs to the Section Orthopedics)
Optimizing Outcomes in Emergency Medicine and Cardiopulmonary Resuscitation submission deadline 20 Oct 2026 | 2 articles | Viewed by 3522 | Submission Open
Keywords: emergency medicine; cardiopulmonary resuscitation; prehospital care; outcome prediction; post-pesuscitation care; advanced life support; emergency response systems; medical ethics; simulation in medicine
(This special issue belongs to the Section Emergency Medicine)
Hip and Knee Arthroplasty: Update on Clinical Management
edited by Maximilian F. Kasparek
submission deadline 20 Oct 2026 | 4 articles | Viewed by 3436 | Submission Open
Keywords: total hip arthroplasty (THA); total knee arthroplasty (TKA); revision arthroplasty; implant fixation; cemented; cementless; hybrid; alignment in TKA; mechanical alignment; kinematic alignment; restricted kinematic alignment; functional alignment; navigation; robotic-assisted surgery; patient-specific instrumentation; additive manufacturing; 3D printing; personalized implant
(This special issue belongs to the Section Orthopedics)
Genitourinary Tumors and Radiation Therapy: Current Advances and Future Directions
edited by Shalini Moningi
submission deadline 20 Oct 2026 | 4 articles | Viewed by 3341 | Submission Open
Keywords: cancer; prostate cancer; bladder cancer; kidney cancer; radiation therapy
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Acute Kidney Injury: Current Challenges and Future Directions in Diagnosis and Treatment submission deadline 20 Oct 2026 | 4 articles | Viewed by 3328 | Submission Open
Keywords: acute kidney injury (AKI); biomarkers; precision nephrology; AKI-to-CKD transition, renal replacement therapy (RRT); subclinical AKI; sepsis-associated AKI; renal recovery
(This special issue belongs to the Section Nephrology & Urology)
Orofacial Pain: Innovations in Treatment Modalities and Patient Care
edited by
submission deadline 20 Oct 2026 | 1 articles | Viewed by 3157 | Submission Open
Keywords: orofacial pain; treatment; patient care; oral dysfunction; chronic pain; burning mouth syndrome; temporomandibular joint pain: oral cenesthopathy; atypical odontalgia; phantom bite syndrome
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Advances in Endodontic Dentistry submission deadline 20 Oct 2026 | 2 articles | Viewed by 2786 | Submission Open
Keywords: antimicrobial agents; biofilm; confocal laser scanning microscopy; endodontic materials; irrigants; microbiome; micro-CT; regenerative endodontics
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Peritoneal Dialysis and Hemodialysis: Early and Late Outcomes submission deadline 20 Oct 2026 | 4 articles | Viewed by 2775 | Submission Open
Keywords: peritoneal dialysis; dialysis; hemodialysis; chronic kidney disease; end-stage renal disease
(This special issue belongs to the Section Nephrology & Urology)
Advances in Cervical Spine Surgery: Techniques, Outcomes, and Complications
edited by and Tae Sik Goh
submission deadline 20 Oct 2026 | 6 articles | Viewed by 2751 | Submission Open
Keywords: cervical spine; fusion assessment; surgical outcomes; cervical alignment; radiological measurements; subsidence; surgical complications
(This special issue belongs to the Section Orthopedics)
New Insights in Joint Arthroplasty—2nd Edition
edited by
submission deadline 20 Oct 2026 | 4 articles | Viewed by 2723 | Submission Open
Keywords: total hip arthroplasty; total knee arthroplasty; robotic-assisted technology and navigation; modern implant materials; modern implant fixation techniques; alignment in TKA; spinopelvic alignment in THA
(This special issue belongs to the Section Orthopedics)
Retinal Diseases: Emerging Therapies and Vision Rehabilitation
edited by
submission deadline 20 Oct 2026 | 2 articles | Viewed by 2635 | Submission Open
Keywords: vitreoretinal disorder; vitrectomy; digital assisted vitrectomy; intraoperative optical coherence tomography; diabetic retinopathy; epiretinal membrane
(This special issue belongs to the Section Ophthalmology)
Bruxism and Temporomandibular Disorders: Assessment and Clinical Insights submission deadline 20 Oct 2026 | 4 articles | Viewed by 2625 | Submission Open
Keywords: bruxism; temporomandibular disorders; TMD; clinical assessment; diagnosis; orofacial pain; masticatory system; interdisciplinary management
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Advances in Plastic and Reconstructive Surgery: Bridging Function, Aesthetics, and Innovation
edited by , Giuseppe Angelo Giovanni Lombardo and
submission deadline 20 Oct 2026 | 4 articles | Viewed by 2458 | Submission Open
Keywords: body-contour; reconstruction; aesthetic; regenerative surgery; plastic surgery; breast reconstruction; microsurgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
New Sights in Retinal Diseases Therapeutics: Innovation and Clinical Practice
edited by , , Stefano Dore and Alfonso Savastano
submission deadline 20 Oct 2026 | 3 articles | Viewed by 2385 | Submission Open
Keywords: retinal diseases; central serous chorioretinopathy; age-related macular degeneration; eye diseases; diabetic retinopathy
(This special issue belongs to the Section Ophthalmology)
Advances in Clinical Craniofacial Reconstructive Surgery
edited by Rami S. Kantar
submission deadline 20 Oct 2026 | 3 articles | Viewed by 2383 | Submission Open
Keywords: craniofacial; craniofacial conditions; craniofacial surgery; cleft; cleft lip; cleft palate; reconstructive surgery; craniofacial anomalies
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Innovations in Surgical and Medical Approaches of Urologic Oncology
edited by
submission deadline 20 Oct 2026 | 2 articles | Viewed by 2298 | Submission Open
Keywords: urologic oncology; robotic surgery; immunotherapy; targeted therapy; image-guided techniques; personalized medicine; minimally invasive surgery; focal therapy
(This special issue belongs to the Section Nephrology & Urology)
Prostate Surgery: The Latest Advances and Future Trends
edited by Akhil K. Das and
submission deadline 20 Oct 2026 | 1 articles | Viewed by 2263 | Submission Open
Keywords: benign prostatic hyperplasia (BPH); minimally invasive surgical therapies (MIST); laser enucleation (HoLEP, ThuLEP); Aquablation; Rezum; robotic prostatectomy; anatomic enucleation
(This special issue belongs to the Section Nephrology & Urology)
Surgical Insights into Foot and Ankle Diseases
edited by Konstantinos Tsikopoulos
submission deadline 20 Oct 2026 | 1 articles | Viewed by 2142 | Submission Open
Keywords: lower limb surgery; infection research; foot and ankle
(This special issue belongs to the Section Orthopedics)
Emerging Diagnosis and Therapies for Psoriasis and Chronic Inflammatory Skin Disorders
edited by Rosa María Izu-Belloso and
submission deadline 20 Oct 2026 | 2 articles | Viewed by 2090 | Submission Open
Keywords: psoriasis; chronic inflammatory skin diseases; immunopathogenesis; biomarkers; targeted therapies; precision medicine; artificial intelligence; biomarkers; real-world evidence; digital dermatology
(This special issue belongs to the Section Dermatology)
Advances in the Clinical Management of Myocardial Infarction
edited by Raef A. Fadel and Ahmad R. Jabri
submission deadline 20 Oct 2026 | 2 articles | Viewed by 2009 | Submission Open
Keywords: myocardial infarction; percutaneous coronary intervention; troponin; antiplatelet therapy; cardiogenic shock; heart failure; ischemic cardiomyopathy; mechanical circulatory support
(This special issue belongs to the Section Cardiology)
Current Updates on Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis
edited by , Georgios Fyrmpas and
submission deadline 20 Oct 2026 | 1 articles | Viewed by 1961 | Submission Open
Keywords: endoscopic sinus surgery; rhinology; chronic rhinosinusitis management; functional endoscopic sinus surgery (FESS); sinonasal inflammation; transnasal approach; postoperative outcomes
(This special issue belongs to the Section Otolaryngology)
Paradigm Changes in Cardiac Surgery and Interventional Cardiology
edited by
submission deadline 20 Oct 2026 | 2 articles | Viewed by 1933 | Submission Open
Keywords: cardiac surgery; trans-catheter interventions; ischaemic heart disease; structural heart disease; electrophysiological interventions; state-of-the-art techniques; golden standards; therapeutic guidelines
(This special issue belongs to the Section Cardiology)
Patient-Reported Outcomes (PROs) in Inflammatory Bowel Disease (IBD) Around the World—2nd Edition
edited by Irina Blumenstein
submission deadline 20 Oct 2026 | 2 articles | Viewed by 1885 | Submission Open
Keywords: inflammatory bowel disease; patient-reported outcomes; symptom burden; quality of life; treatment satisfaction
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Geriatric Fracture Care: Bridging Orthopedics and Gerontology
edited by Tom Knauf and Daphne Asimenia Eschbach
submission deadline 20 Oct 2026 | 3 articles | Viewed by 1773 | Submission Open
Keywords: geriatric fracture; proximal femur fractures; hip fracture, geriatric trauma patient; ortho-geriatric treatment; periprosthetic fracture; end of life decision; orthopedic surgery in the elderly
(This special issue belongs to the Section Geriatric Medicine)
From Substrate to Therapy: Integrating Approaches in Arrhythmia Management
edited by and Ivo Roca-Luque
submission deadline 20 Oct 2026 | 1 articles | Viewed by 1756 | Submission Open
Keywords: cardiac arrhythmias; substrate characterization; non-invasive mapping; ECGi; cardiac imaging; high-density mapping; emerging ablation technologies; pulsed-field ablation; ultra-cryotherapy; stereotactic body radiotherapy; personalized arrhythmia management
(This special issue belongs to the Section Cardiology)
Novel Advances in Lower Limb Trauma and Orthopaedic Surgery
edited by Konstantinos Tsikopoulos and
submission deadline 20 Oct 2026 | 2 articles | Viewed by 1731 | Submission Open
Keywords: lower limb orthopedic surgery; trauma; infection; research
(This special issue belongs to the Section Orthopedics)
Clinical Updates and Perspectives on Transcranial Magnetic Stimulation (TMS)—2nd Edition submission deadline 20 Oct 2026 | 1 articles | Viewed by 1716 | Submission Open
Keywords: non-invasive brain stimulation; transcranial magnetic stimulation; motor cortex; neuroplasticity; motor learning; dementia; stroke; movement disorders; depression; spinal cord; neuropsychiatric disorders
(This special issue belongs to the Section Clinical Neurology)
Pediatric Cardiology: Clinical Insights, Diagnostic Advances, and Therapeutic Challenges submission deadline 20 Oct 2026 | 2 articles | Viewed by 1552 | Submission Open
Keywords: pediatric cardiology; congenital heart disease; cardiac imaging; pediatric arrhythmias; interventional cardiology; cardiomyopathy; heart failure in children; precision medicine; long-term outcomes; transition of care
(This special issue belongs to the Section Clinical Pediatrics)
Clinical Aspects of Male Infertility and Azoospermia
edited by
submission deadline 20 Oct 2026 | 2 articles | Viewed by 1511 | Submission Open
Keywords: azoospermia; non obstructive azoospermia; obstructive azoospermia; microdissection testicular sperm extraction; varicocele; hypogonadotropic hypogonadism
(This special issue belongs to the Section Reproductive Medicine & Andrology)
New Perspectives on Interventional Treatment of Coronary Artery Disease
edited by Mohammad Reza Movahed
submission deadline 20 Oct 2026 | 1 articles | Viewed by 1503 | Submission Open
Keywords: complex coronary intervention; coronary bifurcation; new frontiers in interventional cardiology; calcified lesions; chronic total occlusions; high-pressure balloons; intracoronary lithotripsy
(This special issue belongs to the Section Cardiology)
State of the Art in Obesity Care: From Pathophysiology to Precision Treatment
edited by
submission deadline 20 Oct 2026 | 1 articles | Viewed by 1498 | Submission Open
Keywords: obesity; obesity management; metabolic disease; cardiometabolic risk; bariatric surgery; endoscopic bariatric therapy; anti-obesity pharmacotherapy; glucagon-like peptide-1 receptor agonists; lifestyle intervention; weight loss outcomes; metabolic surgery; cardiovascular risk reduction
(This special issue belongs to the Section Endocrinology & Metabolism)
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