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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cancer Stem Cells and Cellular Therapies in Cancer: Advances and Clinical Prospects

edited by Agnieszka Rybarczyk and Piotr Wierzbicki

submission deadline 20 Jun 2026 | Viewed by 35 | Submission Open

Keywords: cancer stem cells; cell based therapies; innovative therapies in cancer; tumor microenvironment; cell based therapies; preclinical models; immune-based therapies; treatment resistance

(This special issue belongs to the Section Oncology)

Innovative Interventional Approaches in the Treatment of Cardiac Arrhythmias

edited by Karolina Weinmann-Emhardt and Jonas Wormann

submission deadline 20 Jun 2026 | Viewed by 35 | Submission Open

Keywords: cardiac electrophysiology; catheter ablation; atrial fibrillation; ventricular tachycardia; pulmonary vein isolation; three-dimensional mapping; pulsed field ablation; radiofrequency ablation; clinical perspectives

(This special issue belongs to the Section Cardiovascular Medicine)

Towards a Better Understanding of Neuroinflammation in Mental Health

edited by Jesus Cobo

submission deadline 20 Jun 2026 | Viewed by 30 | Submission Open

Keywords: neuroinflammation; biomarkers; peripheral biomarkers; outcomes; bipolar disorders; major depression; mental health; schizophrenia; blood-based inflammatory index; lymphocyte subpopulation

(This special issue belongs to the Section Mental Health)

Clinical Advances and Future Challenges for Occupational Health

edited by

Gabriele D’Ettorre

and Vincenza Pellicani

submission deadline 20 Jun 2026 | Viewed by 27 | Submission Open

Keywords: work-related disease; precision medicine; gender differences; aging workforce; preventive strategies

(This special issue belongs to the Section Epidemiology & Public Health)

Advances in Peripheral Vascular Disease: Diagnosis, Management and Surgical Interventions

edited by Nikolaos Zacharias

submission deadline 20 Jun 2026 | Viewed by 19 | Submission Open

Keywords: atherosclerosis; peripheral artery disease; claudication; critical limb threatening ischemia; infrainguinal bypass; femoral stenting

(This special issue belongs to the Section Vascular Medicine)

Endovascular Stroke Treatment: Latest Advances and Challenges

edited by Daniele Giuseppe Romano and Giulia Frauenfelder

submission deadline 20 Jun 2026 | Viewed by 16 | Submission Open

Keywords: EVT (endovascular stroke treatment); thromboaspiration; thrombectomy; tandem lesion; rescue stenting; ICAD

(This special issue belongs to the Section Clinical Neurology)

Clinical Management of Vitreous and Retinal Disorders

edited by Samuel Asanad

submission deadline 20 Jun 2026 | Viewed by 14 | Submission Open

Keywords: OCT; OCTA; AMD; neurodegenerative disease; surgical techniques; retinal detachment; retinal blood flow; retinal biomarkers; gene therapy

(This special issue belongs to the Section Ophthalmology)

Current Challenges and Innovations in the Treatment of Pancreatitis

edited by Nirav Thosani and Vaibhav Wadhwa

submission deadline 20 Jun 2026 | Viewed by 5 | Submission Open

Keywords: pancreatitis; acute; chronic; biomarkers; endoscopic therapy; minimally invasive interventions; fibrosis; AI modeling

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Advances and New Perspectives in the Diagnosis and Treatment of Schizophrenia

edited by Pierre S. Chue and Oloruntoba J. Oluboka

submission deadline 22 Jun 2026 | Viewed by 37 | Submission Open

Keywords: psychopharmacology; schizophrenia; long-acting injectable therapy; recovery; team approach to care; integrated care; clozapine; habilitation; rehabilitation; early intervention

(This special issue belongs to the Section Mental Health)

Clinical Insights and Challenges into Cognitive and Mental Health in Older Adults

edited by Dariusz Krok

submission deadline 23 Jun 2026 | Viewed by 58 | Submission Open

Keywords: clinical insights; cognitive and mental health; older adults; psychosomatic interventions; person-centered care

(This special issue belongs to the Section Mental Health)

Headache: Updates on the Assessment, Diagnosis and Treatment

edited by

Ernesto Anarte-Lazo

and

Carlos Bernal-Utrera

submission deadline 25 Jun 2026 | 7 articles | Viewed by 12214 | Submission Open

Keywords: headache; migraine; tension-type headache; cervicogenic headache; therapeutic exercise

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances of Aesthetic Plastic Surgery and Aesthetic Medicine

edited by Valentina Pinto and Rosalba Russo

submission deadline 25 Jun 2026 | Viewed by 138 | Submission Open

Keywords: aesthetic plastic surgery; aesthetic medicine; emerging technologies and devices in aesthetics; regenerative medicine and surgery; vulvovaginal surgery; complications in aesthetic medicine

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Multidisciplinary Care in Severe Traumatic Brain Injury Across the Continuum of Care: Acute, Rehabilitative, and Chronic Management

edited by Ryan Martin, Davin Quinn and Nicholas Race

submission deadline 25 Jun 2026 | Viewed by 91 | Submission Open

Keywords: severe traumatic brain injury; multidisciplinary; rehabilitation; advance practice providers; ancillary health; therapy; neuropsychology; nutrition

(This special issue belongs to the Section Brain Injury)

Cardiometabolic Disease and Atherosclerosis: Epidemiology, Prevention, Diagnosis, and Clinical Treatment—2nd Edition

edited by

Evangelos Oikonomou

and Konstantinos Mourouzis

submission deadline 25 Jun 2026 | Viewed by 82 | Submission Open

Keywords: atherosclerosis; obesity; cardiometabolic disease; prevention; diabetes mellitus; endothelium; arteriosclerosis; coronary artery disease

(This special issue belongs to the Section Cardiology)

Diet and Nutritional Aspects in Cardiovascular-Kidney-Metabolic Diseases (CKM)

edited by Krishnaswami Vijayaraghavan

submission deadline 25 Jun 2026 | Viewed by 80 | Submission Open

Keywords: cardiovascular-kidney-metabolic diseases (CKM); obesity; diabetes and metabolic syndrome; dietary factors; nutritional aspects; food policy and food security; chronic kidney disease; heart disease; technology

(This special issue belongs to the Section Clinical Nutrition & Dietetics)

Recent Clinical Advances in Cardiac Rehabilitation: 2nd Edition

edited by

Tomasz Rechciński

submission deadline 25 Jun 2026 | Viewed by 70 | Submission Open

Keywords: cardiac rehabilitation; kinesiotherapy; psychological support; lifestyle modifications; myocardial infarction; heart failure

(This special issue belongs to the Section Cardiology)

Geriatric Cardiology: Clinical Advances and Comprehensive Management

edited by

Iris Parrini

submission deadline 25 Jun 2026 | Viewed by 62 | Submission Open

Keywords: geriatric assessment; management of cardiovascular disease; cardiovascular health; geriatric cardiology; frailty evaluation and management

(This special issue belongs to the Section Geriatric Medicine)

Advances in Minimally Invasive and Endoscopic Neurosurgery

edited by Shunsuke Shibao

submission deadline 25 Jun 2026 | Viewed by 55 | Submission Open

Keywords: minimally invasive; endoscopic; keyhole; endonasal; transorbital; skull base; complications; surgical outcomes; technical innovations; robotic neurosurgery

(This special issue belongs to the Section Clinical Neurology)

Surgical Innovations in Pediatric Orthopedics

edited by

Hoon Park

submission deadline 25 Jun 2026 | Viewed by 52 | Submission Open

Keywords: pediatric orthopedics; surgical innovation; growth modulation; absorbable implant; 3D printing

(This special issue belongs to the Section Orthopedics)

Oral Health and Systemic Diseases: Clinical Insights

edited by

Fabio Piras

submission deadline 25 Jun 2026 | Viewed by 52 | Submission Open

Keywords: oral health; endodontics; orthodontic; periodontal disease; dental caries

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Myopic Optic Neuropathy (MON) and Glaucomatous Optic Neuropathy (GON): Current Concepts and Clinical Implications

edited by

Etsuo Chihara

submission deadline 25 Jun 2026 | Viewed by 51 | Submission Open

Keywords: myopic optic neuropathy; glaucomatous optic neuropathy; tilting; axonal transport; lamina cribrosa

(This special issue belongs to the Section Ophthalmology)

Diagnosis and Management of Corneal Diseases

edited by Nicola Cardascia

submission deadline 25 Jun 2026 | Viewed by 47 | Submission Open

Keywords: corneal surgery; lamellar keratoplasty; bioengineered corneal grafts; regenerative medicine; cell-based therapies; tissue-based therapies; Intraoperative imaging; corneal wound healing; lmmune modulation; graft survival; translational research; multimodal diagnostics; clinical outcomes; corneal transparency restoration; ophthalmic surgical innovation

(This special issue belongs to the Section Ophthalmology)

Upper Airway Management in Obstructive Sleep Apnea: Latest Advances and Future Perspectives

edited by Shintaro Chiba

submission deadline 25 Jun 2026 | Viewed by 43 | Submission Open

Keywords: obstructive sleep apnea (OSA); sleep surgery; upper airway stimulation (UAS); upper airway physiology

(This special issue belongs to the Section Respiratory Medicine)

Technological Advancements and Clinical Innovations in Diagnostic and Interventional Radiology: 2nd Edition

edited by

Massimo Venturini

and

Federico Fontana

submission deadline 25 Jun 2026 | Viewed by 38 | Submission Open

Keywords: artificial intelligence; radiomics; image fusion; spectral computed tomography; functional magnetic resonance im-aging; CO2 angiography; balloon-occluded transcatheter arterial chemoembolization

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Advances in Immunohematology: From Pathophysiology to Tailored Treatments

edited by

Giorgio Costagliola

submission deadline 25 Jun 2026 | Viewed by 37 | Submission Open

Keywords: autoimmune cytopenia; hemophagocytic lymphohistiocytosis; inborn errors of immunity; lymphoproliferative diseases; malignancy; monoclonal antibodies; secondary immunodeficiency; vaccination

(This special issue belongs to the Section Immunology & Rheumatology)

Cancer Prevention and Early Detection: Epidemiological Approaches and Public Health Strategies

edited by

Carmen Martos

and

Francesco Giusti

submission deadline 25 Jun 2026 | Viewed by 35 | Submission Open

Keywords: cancer prevention; cancer screening; risk factors; cancer treatment; health information systems; cancer registry; cancer inequalities

(This special issue belongs to the Section Epidemiology & Public Health)

Cystic Fibrosis: Management Strategies and Patient Outcomes

edited by Marta Rachel

submission deadline 25 Jun 2026 | Viewed by 35 | Submission Open

Keywords: cystic fibrosis; multidisciplinary care; personalized medicine; patient outcomes; telemedicine; pediatric pulmonology; CFTR modulators; chronic disease management

(This special issue belongs to the Section Respiratory Medicine)

Clinical Management of Traumatic Brain Injury

edited by Adam James Wells and Peter Hutchinson

submission deadline 25 Jun 2026 | Viewed by 34 | Submission Open

Keywords: traumatic brain injury; clinical management TBI; neurocritical care; neuromonitoring; trauma neurosurgery; artificial intelligence

(This special issue belongs to the Section Clinical Neurology)

Clinical Advancements in Laparoscopic Surgery for Gastrointestinal Diseases

edited by

Nikolaos Pararas

submission deadline 25 Jun 2026 | Viewed by 29 | Submission Open

Keywords: laparoscopic surgery; minimally invasive surgery; gastrointestinal diseases; colorectal cancer; gastric cancer; robotic surgery; fluorescence imaging; endoscopic-laparoscopic hybrid surgery; surgical oncology; future perspectives

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Bariatric Surgery: Current Status and Emerging Clinical Trends

edited by Collin E. M. Brathwaite

submission deadline 25 Jun 2026 | Viewed by 19 | Submission Open

Keywords: bariatric surgery; metabolic surgery; obesity; GLP-1 receptor agonists; robotic surgery; revisional surgery; weight regain; metabolic mechanisms; enhanced recovery; surgical innovation

(This special issue belongs to the Section General Surgery)

Human Immunodeficiency Virus: From Clinical Studies to Patient Outcomes

edited by Vítor Duque

submission deadline 25 Jun 2026 | Viewed by 16 | Submission Open

Keywords: HIV/AIDS; clinical trials; patient outcomes; clinical translational research

(This special issue belongs to the Section Infectious Diseases)

Integrating Artificial Intelligence and Contextual Factors in Emergency Care

edited by Ancor Sanz-García and

José Luis Martín-Conty

submission deadline 25 Jun 2026 | Viewed by 12 | Submission Open

Keywords: emergency care; artificial intelligence; early warning systems; data-driven healthcare; predictive analytics

(This special issue belongs to the Section Emergency Medicine)

Advances in General and Regional Anaesthesia

edited by Michał Jan Stasiowski,

Nikola Zmarzły

and

Beniamin Oskar Grabarek

submission deadline 26 Jun 2026 | Viewed by 53 | Submission Open

Keywords: general anaesthesia; regional anaesthesia; ropivacaine; bupivacaine; postoperative pain; postoperative nausea and vomiting; preventive analgesia; rescue opioid analgesia; total intravenous anaesthesia; inhalational anaesthesia

(This special issue belongs to the Section Anesthesiology)

Youth Sports Injuries: From Prevalence to Prevention

edited by Swarup Mukherjee and

Gregory C. Bogdanis

submission deadline 30 Jun 2026 | 4 articles | Viewed by 11038 | Submission Open

Keywords: youth sports injuries; musculoskeletal injuries; injury prevention; sport safety; youth athletes

(This special issue belongs to the Section Sports Medicine)

Ergonomics and Low Back Pain: Integrative Approaches to Prevention, Assessment and Management

edited by

Janan Abbas

and

Deborah Alperovitch

submission deadline 30 Jun 2026 | Viewed by 67 | Submission Open

Keywords: advanced in diagnostic methods; therapeutic innovations; multidisciplinary and personalized care models; prevention and rehabilitation; non-pharmacological strategies; ergonomics; biomechanics

(This special issue belongs to the Section Orthopedics)

Integrating a One Health Approach into Antimicrobial Stewardship and Shared Care in Wound Management

edited by Joanna F. Blackburn

submission deadline 30 Jun 2026 | Viewed by 44 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial resistance; one health; shared care; wound care; wound care management; chronic wound care; acute wound care; digital health; wound diagnostics; antimicrobials; antibiotics

(This special issue belongs to the Section Dermatology)

Clinical Advances in Aortic Disease and Revascularization: 2nd Edition

edited by Andrej Udelnow

submission deadline 30 Jun 2026 | Viewed by 40 | Submission Open

Keywords: aortic disease; aortic aneurysm; endovascular aortic repair; atherosclerosis; aortic dissections; overall survival; quality of life; intravascular ultrasound

(This special issue belongs to the Section Vascular Medicine)

New Clinical Insights into Acute Respiratory Failure

edited by

Christophe Guervilly

submission deadline 30 Jun 2026 | Viewed by 19 | Submission Open

Keywords: acute respiratory failure; pathophysiology; advances respiratory monitoring; respiratory support strategies; respiratory mechanics; mechanical ventilation; respiratory drive; patient-ventilator asynchrony

(This special issue belongs to the Section Intensive Care)

Advances in Anterior Cruciate Ligament Injury Treatment

edited by Goran Vrgoč

submission deadline 1 Jul 2026 | Viewed by 15 | Submission Open

Keywords: anterior cruciate ligament (ACL) injury; ACL reconstruction techniques; nonoperative ACL treatment; ACL graft; knee biomechanics; return-to-sport assessment; ACL rehabilitation; neuromuscular and proprioceptive training; athletic injuries; performance-enhancing substances; reinjury prevention; psychological readiness; ACL performance testing; osteoarthritis risk

(This special issue belongs to the Section Orthopedics)

Modern Challenges in Pediatric Endocrinology: From Growth Disorders to Metabolic Dysregulation

edited by Katarzyna A. Majewska and Piotr Fichna

submission deadline 2 Jul 2026 | Viewed by 46 | Submission Open

Keywords: growth hormone deficiency; growth hormone therapy; short stature; obesity; obesity complications; obesity treatment; insulin resistance; prediabetes; type 1 diabetes; type 2 diabetes; hypothyroidism; hyperthyroidism; autoimmune thyroiditis; puberty disorders

(This special issue belongs to the Section Clinical Pediatrics)

Visualizing Cardiac Function: Advances in Modern Imaging Diagnostics

edited by Dafni Charisopoulou and

Michael Henein

submission deadline 10 Jul 2026 | Viewed by 50 | Submission Open

Keywords: cardiac imaging; echocardiography; coronary artery disease; valve disease; heart failure

(This special issue belongs to the Section Cardiology)

Emerging Biomarkers and Novel Diagnostic Tools in Respiratory Diseases: From Bench to Bedside

edited by

Silvano Dragonieri

and

Andras Bikov

submission deadline 10 Jul 2026 | Viewed by 44 | Submission Open

Keywords: respiratory diseases; biomarkers; non-invasive approaches; novel diagnostic tests; precision medicine; personalized therapy; disease phenotyping; diagnostic tools; functional biomarkers; imaging biomarkers; molecular biomarkers

(This special issue belongs to the Section Respiratory Medicine)

Endoscopic Therapy in Gastroesophageal Reflux Disease (GERD): Current Evidence, Techniques, and Future Perspectives

edited by Pier Alberto Testoni

submission deadline 10 Jul 2026 | Viewed by 37 | Submission Open

Keywords: gastroenterology; gastroesophageal reflux disease; GERD; esophageal diseases; endoscopic therapy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Gynecologic Cancers: Integrating Established Standards and Innovative Approaches

edited by Radu Vladareanu and Liviu Bilteanu

submission deadline 10 Jul 2026 | Viewed by 27 | Submission Open

Keywords: gynecological cancers; cervical cancer; ovarian cancer; endometrial cancer; vulvar and vaginal tumors; uterine sarcoma; fertility preservation; robotic surgery; image-guided radiotherapy (IGRT); brachytherapy; proton and FLASH radiotherapy; immunotherapy; radiomics; artificial intelligence; digital twin; multimodal treatment; survivorship and quality of life

(This special issue belongs to the Section Oncology)

Personalized Medicine: Future Perspectives on Personalized Oral and Maxillofacial Surgery

edited by

Cosmin Ioan Faur

, Rareș Calin Roman and Mihaela Carmen Hedeşiu

submission deadline 15 Jul 2026 | 1 articles | Viewed by 618 | Submission Open

Keywords: head and neck surgery; head and neck oncology; head and neck reconstructions; personalized medicine; artificial intelligence; head and neck trauma; integrative medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Aortic Dissection: Current Trends, Complexities, and Future Directions

edited by Aung Ye Oo

submission deadline 15 Jul 2026 | Viewed by 68 | Submission Open

Keywords: aortic dissection; aortic surgery; hybrid and endovascular repair; diagnostic delay; systems of care; patient safety; biomarkers and imaging; postoperative outcomes; multidisciplinary collaboration in aortic disease management

(This special issue belongs to the Section Cardiovascular Medicine)

Fertility Challenges: Modern Management Strategies and Assisted Reproductive Technologies

edited by

Luigi Carbone

submission deadline 15 Jul 2026 | Viewed by 48 | Submission Open

Keywords: infertility; assisted reproductive technologies (ARTs); ovarian reserve; antral follicle count (AFC); anti-mullerian hormone (AMH); fertility preservation; IVF pregnancy; ovarian stimulation; embryo selection

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Approaches to Prevention and Management of Postoperative Complications in Minimally Invasive Surgery

edited by Shingo Tsujinaka

submission deadline 15 Jul 2026 | Viewed by 45 | Submission Open

Keywords: minimally invasive surgery; postoperative complications; preventive measures; risk assessment; surgical techniques; patient optimization; complication management; surgical outcomes; patient satisfaction; patient-reported outcomes

(This special issue belongs to the Section General Surgery)

Measuring Recovery After Arthroplasty: Optimal Tools and Timing of Outcome Assessment

edited by

Nicholas David Clement

submission deadline 15 Jul 2026 | Viewed by 42 | Submission Open

Keywords: arthroplasty; hip; knee; recovery; outcomes; assessment

(This special issue belongs to the Section Orthopedics)

Neurosurgery Advancements: Techniques and Patient Outcomes

edited by Vianney Gilard

submission deadline 15 Jul 2026 | Viewed by 33 | Submission Open

Keywords: neurosurgery; minimally invasive surgery; endoscopic spine surgery; intraoperative imaging; neuro-oncology; functional neurosurgery; neurovascular surgery; patient outcomes

(This special issue belongs to the Section Clinical Neurology)

Displaying special issue 1351-1400 on page 28 of 31.

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