Cancer Stem Cells and Cellular Therapies in Cancer: Advances and Clinical Prospects
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Oncology".
Deadline for manuscript submissions: 20 June 2026 | Viewed by 16
Special Issue Editors
Interests: patient-derived cell line; kidney cancer; penile cancer; rare urogenital diseases; tumor microenvironment; cancer stem cells; primary cell line; novel cancer therapies
Interests: kidney cancer; penile cancer; colorectal cancer; tumor suppressing gene; targeted therapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The Special Issue “Cancer Stem Cells and Cellular Therapies in Cancer: Advances and Clinical Prospects” is devoted to presenting state-of-the-art progress and addressing enduring challenges in the elucidation and therapeutic targeting of cancer stem cells (CSCs). CSCs constitute a distinct subpopulation of tumor cells that play a central role in tumor initiation, progression, metastasis, and the development of therapeutic resistance. Despite substantial advances in oncology, the persistence of CSCs continues to pose a major impediment to the achievement of durable remission and long-term disease control.
This Special Issue seeks to integrate interdisciplinary research. Particular emphasis is placed on immune-based and stem cell–derived cellular therapies that hold promise for selectively targeting CSCs and overcoming conventional therapeutic limitations.
The scope of this issue covers mechanisms of resistance to cancer treatment, preclinical model development, and clinical applications of cell therapies, including CAR-T, natural killer (NK), and dendritic cell therapies.
By bringing together researchers from the fields of oncology, immunology, molecular biology, and regenerative medicine, this Special Issue aims to foster cross-disciplinary collaboration, accelerate the clinical translation of CSC-targeted and cell-based therapeutic strategies, and advance collective efforts toward surmounting one of the most intractable challenges in contemporary oncology.
Dr. Agnieszka Rybarczyk
Prof. Piotr Wierzbicki
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cancer stem cells
- cell based therapies
- innovative therapies in cancer
- tumor microenvironment
- cell based therapies
- preclinical models
- immune-based therapies
- treatment resistance
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