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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Research in Leukemia

edited by Juan Manuel Mejia-Arangure

submission deadline 30 Nov 2026 | Viewed by 309 | Submission Open

Keywords: leukemia; molecular biology; genetic testing; epigenomics; targeted therapy; precision medicine; diagnostic techniques; molecular pathways

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Integrative Regenerative Medicine: Bridging Molecular Mechanisms and Therapeutic Applications

edited by

Jerran Santos

submission deadline 30 Nov 2026 | Viewed by 303 | Submission Open

Keywords: regenerative medicine; stem cells; molecular mechanisms; tissue engineering; organoids; biomaterials; biofabrication; clinical translation; cell therapy; integrative biology

(This special issue belongs to the Section Molecular Biology)

Novel Diagnostic and Theragnostic Strategies in Brain Tumors

edited by Andrea Cimini and Laura Travascio

submission deadline 30 Nov 2026 | Viewed by 299 | Submission Open

Keywords: brain tumor; novel diagnostic and theragnostic approaches; neuro-oncology; precision medicine

(This special issue belongs to the Section Molecular Oncology)

Plant–Microbe Interactions in Alleviation of Abiotic Stress in Plants

edited by

Marzena Sujkowska-Rybkowska

submission deadline 30 Nov 2026 | Viewed by 297 | Submission Open

Keywords: abiotic stresses; plant– microbe interactions; symbiotic microbes; stress adaptation; stress-responsive genes; physio-logical responses

(This special issue belongs to the Section Molecular Plant Sciences)

Recent Genetic Insights into Neurodevelopmental Disorders

edited by Maria Cristina Aspromonte and Emanuela Dazzo

submission deadline 30 Nov 2026 | Viewed by 295 | Submission Open

Keywords: neurodevelopmental disorders; autism spectrum disorder; intellectual disability; attention deficit hyperactivity disorder; epilepsy; motor disorders; chromosomal rearrangements; genetic variant; integrative omics approaches

(This special issue belongs to the Section Molecular Neurobiology)

Ferroptosis: Mechanisms and Roles in Diseases

edited by Yuquan Chen

submission deadline 30 Nov 2026 | Viewed by 290 | Submission Open

Keywords: ferroptosis; iron metabolism; lipid peroxidation; oxidative stress; endocrine diseases; metabolic disorders; environmental exposures; circadian rhythm; redox signaling; cell death

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Apoptosis in Health and Disease: Recent Advances and Future Directions

edited by Shabnam Malik

submission deadline 30 Nov 2026 | Viewed by 290 | Submission Open

Keywords: apoptosis; programmed cell death; health and disease; cellular homeostasis; cancer; neurodegenerative disorders

(This special issue belongs to the Section Molecular Biology)

Advances in the Molecular Biology of Lipids and Mitochondria

edited by

Alejandra Espinosa

submission deadline 30 Nov 2026 | Viewed by 288 | Submission Open

Keywords: lipids; lipid transport mechanisms; lipid peroxidation; mitochondrial integrity; bioenergetics; mitochondrial phospholipid

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Advances in Osteogenesis: 2nd Edition

edited by

Andrea Del Fattore

submission deadline 30 Nov 2026 | Viewed by 288 | Submission Open

Keywords: osteogenesis; osteoblast; bone formation; disease; bone

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

New Insight into Pathogen Stress Effects on Plant Structure and Metabolism

edited by

Edmund Kozieł

and

Katarzyna Otulak-Kozieł

submission deadline 30 Nov 2026 | Viewed by 284 | Submission Open

Keywords: plant– pathogen interaction; innate immunity; ultrastructure; plant defense systems; plant physiology; signal transduction; resistance genes

(This special issue belongs to the Section Molecular Plant Sciences)

Radiofrequency on Human Health: A Molecular Perspective

edited by

Mariateresa Allocca

and Valentina Peluso

submission deadline 30 Nov 2026 | Viewed by 281 | Submission Open

Keywords: radiofrequency electromagnetic field; bioelectromagnetics; health effects; biological effects; molecular mechanisms; interaction mechanisms; electromagnetic risk assessment; biomedical application

(This special issue belongs to the Section Molecular Biophysics)

Innovative Nano- and Microcarrier Systems for Targeted Delivery

edited by

Matteo Perra

submission deadline 30 Nov 2026 | Viewed by 275 | Submission Open

Keywords: drug delivery systems; nanocarriers; microcarriers; targeted delivery; controlled release; bioactive compounds; nanomedicine

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Mechanisms in Mucosal Immunity

edited by

Mónica Vermeulen

submission deadline 30 Nov 2026 | Viewed by 268 | Submission Open

Keywords: mucosal immunity; metabolism; innate memory; trainers and inflammatory stimuli

(This special issue belongs to the Section Molecular Immunology)

Therapeutic Strategies for Surgical Tissue Damage, Repair and Regeneration

edited by

Alex K. Wong

submission deadline 30 Nov 2026 | Viewed by 265 | Submission Open

Keywords: surgical injury; tissue regeneration; vasculogenesis; wound healing in compromised settings; molecular therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Roles and Mechanisms of Non-Coding RNAs in Human Health and Disease: 2nd Edition

edited by

Marco Ragusa

and

Cristina Barbagallo

submission deadline 30 Nov 2026 | Viewed by 263 | Submission Open

Keywords: non-coding RNAs; microRNAs; long non-coding RNAs; circular RNAs; biomarkers; polymorphisms; cancer; degenerative diseases; therapy

(This special issue belongs to the Section Molecular Genetics and Genomics)

Translational Advances in Melanoma Molecular Research

edited by

Marcela S. Villaverde

submission deadline 30 Nov 2026 | Viewed by 262 | Submission Open

Keywords: melanoma; molecular targets; resistance mechanism; future advances; metabolic reprogramming

(This special issue belongs to the Section Molecular Oncology)

Modern Synthetic Pathways for Anticancer Drug Discovery

edited by

Łukasz Struk

submission deadline 30 Nov 2026 | Viewed by 261 | Submission Open

Keywords: new anticancer agents; bioactive molecules; drug design; drug synthesis; cancer therapy; medicinal chemistry

(This special issue belongs to the Section Molecular Oncology)

Hydrogels and Nanogels: Revolutionizing Drug Delivery and Disease Detection

edited by Enrico Gallo

submission deadline 30 Nov 2026 | Viewed by 259 | Submission Open

Keywords: hydrogel and nanogel networks; supramolecular systems; hydrogel synthesis and analysis; nanogel preparation and characterization; nanostructured fibers; multiphase gels; biomedicine applications; supramolecular probes for imaging; hydrogels and nanogels as drug release systems; coatings and surface treatments; polymeric systems; peptide-based supramolecular systems

(This special issue belongs to the Section Materials Science)

Gene Therapy for Ocular Diseases: Mechanisms, Advances and Therapeutic Applications

edited by Jiang-Hui Wang

submission deadline 30 Nov 2026 | Viewed by 257 | Submission Open

Keywords: AAV; capsid engineering; gene therapy; retinal diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in the Reprogramming of Mitochondrial Signalling and Metabolism in Cancers

edited by

Maria Rosa Ciriolo

and

Fabio Ciccarone

submission deadline 30 Nov 2026 | Viewed by 253 | Submission Open

Keywords: mitochondrial dynamic; mitochondrial biogenesis; mitochondrial transfer; mitochondrial targeting; mitophagy; oxidative metabolism; mtDNA; ROS; oncometabolism

(This special issue belongs to the Section Molecular Oncology)

Bioactive Peptides from Natural Sources: Pharmacological Effects, Recombinant Expression, Modification, Molecular Mechanisms, and Therapeutic Potential

edited by Linchun Shi

submission deadline 30 Nov 2026 | Viewed by 243 | Submission Open

Keywords: bioactive peptides; functional peptides; antimicrobial peptides; host-defense peptides; venom peptides; ribosomally synthesized and post-translationally modified peptides; peptide precursor gene families; comparative genomics; phylogeny; structure– activity relationship

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Mechanisms, Epigenetics and Therapeutics in Liver Cirrhosis

edited by Ana Soledad Sandoval-Rodríguez

submission deadline 30 Nov 2026 | Viewed by 243 | Submission Open

Keywords: liver cirrhosis; molecular pathogenesis; fibrosis and inflammation; epigenetics; hepatocellular carcinoma (HCC); viral hepatitis; molecular mechanism; hepatic nutrition; therapeutic targets; translational hepatology; MASLD; ALD

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Ferroptosis in Cancer Biology and Therapy

edited by Alessandra Di Paola and Elvira Pota

submission deadline 30 Nov 2026 | Viewed by 241 | Submission Open

Keywords: ferroptosis; cancer biology; tumor microenvironment; therapeutic targeting; anticancer immunity; targeted therapy

(This special issue belongs to the Section Molecular Oncology)

Stem Cell Research in Urological, Hepatological, and Ophthalmological Disorders

edited by Yuanyuan Zhang

submission deadline 30 Nov 2026 | Viewed by 240 | Submission Open

Keywords: stem cells; induced pluripotent stem cells (iPSCs); exosomes; tissue regeneration; urinary incontinence; kidney dysfunction; ocular disorders; molecular mechanisms

(This special issue belongs to the Section Molecular Biology)

Molecular Advances in Brucella Research

edited by

Angel Oñate

submission deadline 30 Nov 2026 | Viewed by 235 | Submission Open

Keywords: Brucella abortus; molecular pathogenesis; host– pathogen interaction; virulence factors; oxidative stress response; intracellular survival; immune evasion; exosomes; vaccine development

(This special issue belongs to the Section Molecular Microbiology)

Natural Product Research: From Isolation to Functional Validation

edited by

Radosław Kowalski

submission deadline 30 Nov 2026 | Viewed by 233 | Submission Open

Keywords: natural products; secondary metabolites; bioactive compounds; extraction and isolation; green extraction; structural elucidation; metabolomics profiling (LC– HRMS/MS); dereplication; functional validation; molecular mechanisms; molecular docking; molecular modeling; ligand– protein interactions; structure– activity relationship (SAR); in vitro and in vivo studies; bioavailability and safety; antimicrobial activity; antioxidant activity; anticancer activity

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Interdisciplinary Molecular Design: Catalysis, Therapeutics, and Biomaterials

edited by

Zhiwei Yang

submission deadline 30 Nov 2026 | Viewed by 227 | Submission Open

Keywords: intelligent molecular design; computational catalysis; antibody and protein engineering; biomaterials design; molecular dynamics simulations; AI in drug discovery

(This special issue belongs to the Section Molecular Biophysics)

Endometrial Cancer: From Molecular Mechanisms to Treatment

edited by Ursula Catena

submission deadline 30 Nov 2026 | Viewed by 226 | Submission Open

Keywords: endometrial cancer; molecular mechanisms; biomarkers; targeted therapy; immunotherapy; genomics; precision medicine

(This special issue belongs to the Section Molecular Oncology)

Multi-Omic Data Integration in Oncology

edited by Hung-Yu Lin and

Hsing-Ju Wu

submission deadline 30 Nov 2026 | Viewed by 223 | Submission Open

Keywords: bioinformatics; multi-omics at bulk level; single-cell omics; spatial multi-omics; metabolomics; proteomics; pharmacogenomics; tumor microenvironment; tumor molecular profiling; therapy resistance

(This special issue belongs to the Section Molecular Informatics)

Bioactive Phenolic Compounds in Human Health and Disease: Second Edition

edited by

Andrei Lobiuc

submission deadline 30 Nov 2026 | Viewed by 223 | Submission Open

Keywords: novel sources; synthesis; biological activity; molecular interactions; pharmacodynamics; pharmacokinetics; assay development; microbiota; sources and intake

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research on Foodborne Pathogens and Biofilms

edited by

Arturo Ramirez-Peralta

submission deadline 30 Nov 2026 | Viewed by 217 | Submission Open

Keywords: foodborne pathogens; biofilms; food

(This special issue belongs to the Section Molecular Microbiology)

Molecular Mechanisms of Adipose Tissue Dysfunction

edited by

Stefano Quarta

submission deadline 30 Nov 2026 | Viewed by 213 | Submission Open

Keywords: adipose tissue dysfunction; adipogenesis; immunometabolism and adipokines; mitochondrial dysfunction; extracellular vesicles; fibrosis and ECM remodeling; lipid metabolism; browning and beigeing; metabolic biomarkers and therapeutic targets; adipose-derived stem cells

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Toxicology of Cyanobacterial Toxins

edited by

Carlos García

submission deadline 30 Nov 2026 | Viewed by 212 | Submission Open

Keywords: toxicology; cyanotoxins; cyanobacteria; harmful effects; health risk

(This special issue belongs to the Section Molecular Toxicology)

Design, Synthesis and Development of Anticancer Drugs Targeting the Tumor Microenvironment

edited by

Yoshihiro Uto

submission deadline 30 Nov 2026 | Viewed by 212 | Submission Open

Keywords: anticancer drugs; tumor microenvironment; in vivo model; cancer-associated fibroblast; tumor-associated macrophage; tumor hypoxia; tumor endothelial cells

(This special issue belongs to the Section Molecular Oncology)

The Design, Synthesis, and Application of Functional Porous Materials

edited by Qinhe Pan,

Shenzhen Chang

and

Shi-Cheng Wang

submission deadline 30 Nov 2026 | Viewed by 211 | Submission Open

Keywords: porous materials; functional guest species; functionalization; luminescence; electrochemistry; stimulus response; adsorption; sensing; photoelectric; catalysis

(This special issue belongs to the Section Materials Science)

Plant Natural Products: New Advances in the Discovery, Regulation, and Engineering

edited by

Thiago Barbosa Cahú

and

Bruno Veras

submission deadline 30 Nov 2026 | Viewed by 207 | Submission Open

Keywords: polyphenols; glycoconjugates; plant protein; polysaccharides; crop production; processing wastes; circular economy; techno-economical evaluation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Next-Generation Sequencing Assays in Precision Oncology

edited by Kakoli Das,

Jens Samol

and Chuah Khoon Leong

submission deadline 30 Nov 2026 | Viewed by 194 | Submission Open

Keywords: precision oncology; NGS; genomics; transcriptomics; proteomics; molecular pathology; multi-omics integration

(This special issue belongs to the Section Molecular Oncology)

Smart and Sustainable Hydrogels for Environmental Applications

edited by Rolando Chamy

submission deadline 30 Nov 2026 | Viewed by 193 | Submission Open

Keywords: hydrogel; biomaterials; sustainable materials; regenerative medicine

(This special issue belongs to the Section Materials Science)

Molecular Pharmacognosy and Phytochemical Profiling in Natural Product Research

edited by Kamran Ashraf

submission deadline 30 Nov 2026 | Viewed by 191 | Submission Open

Keywords: molecular pharmacognosy; phytochemical profiling; natural products; bioactive compounds; metabolomics; chemometrics; LC– MS/MS; GC– MS; molecular mechanisms; drug discovery

(This special issue belongs to the Section Molecular Plant Sciences)

Deep Learning Biomarkers for Cancer Therapy

edited by

Hüseyin Fırat

submission deadline 30 Nov 2026 | Viewed by 191 | Submission Open

Keywords: deep learning; cancer biomarkers; precision oncology; histopathology; medical imaging; explainable AI; cancer detection; cancer segmentation; digital pathology; clinical decision support

(This special issue belongs to the Section Molecular Oncology)

Molecular Interactions Between Bacteria and Viruses: Mechanisms and Pathogenic Insights

edited by Vasilis Petrakis

submission deadline 30 Nov 2026 | Viewed by 191 | Submission Open

Keywords: viral infections; HIV/AIDS; SARS-CoV-2; antibiotics; antimicrobial resistance; antiviral agents

(This special issue belongs to the Section Molecular Microbiology)

Pathogenesis of Pathogenic Fungi: The Era of AI and New Technologies

edited by

Paul Wai Kei Tsang

submission deadline 30 Nov 2026 | Viewed by 189 | Submission Open

Keywords: artificial intelligence; molecular diagnosis and detection; therapeutic targeting; resistance and prediction; host relationships; immunity

(This special issue belongs to the Section Molecular Microbiology)

Molecular Crosstalk Between Allergens, Microbes, and the Mucosal Immune System

edited by Stefanie Gilles

submission deadline 30 Nov 2026 | Viewed by 184 | Submission Open

Keywords: allergens and innate immunity; mucosal immune signaling; epithelial barrier and inflammation; pathogen-allergen crosstalk; bioaerosol exposure; allergen recognition mechanisms; environmental immunology

(This special issue belongs to the Section Molecular Immunology)

Current Research in DNA Methylation

edited by Mikhail M. Baryshev

submission deadline 30 Nov 2026 | Viewed by 179 | Submission Open

Keywords: DNA methylation; cancer-specific DNA methylation; epigenetics; lncRNA; CpG; CHG; CHH; CCWGG methylation types; chromatin remodeling

(This special issue belongs to the Section Biochemistry)

Encephalitis: Mechanisms, Models, and Treatment Strategies

edited by

Hasan Tarik Atmaca

and

Gungor Cagdas Dincel

submission deadline 30 Nov 2026 | Viewed by 176 | Submission Open

Keywords: encephalitis; neuroinflammation; host– pathogen interactions; central nervous system; experimental models; comparative medicine; veterinary medicine; human medicine; molecular mechanisms; treatment strategies

(This special issue belongs to the Section Molecular Neurobiology)

Newest Antibacterial Applications of Metal Nanoparticles

edited by

Serhat Keser

submission deadline 30 Nov 2026 | Viewed by 175 | Submission Open

Keywords: metal oxides; hydroxyapatites; antibacterial; gram positive; gram negative; nanoparticles; antibacterial; antibacterial resistance; bioactivity; biocompatibility; metal-based nanoparticles

(This special issue belongs to the Section Molecular Nanoscience)

Trace Elements in Nutrition and Health Research

edited by

Kyria Jayanne Clímaco Cruz

submission deadline 30 Nov 2026 | Viewed by 175 | Submission Open

Keywords: trace elements; essential elements; toxic trace elements; micronutrient homeostasis; bioavailability; nutrient interactions; deficiency and overload; human health; disease prevention

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Research on Molecular Mechanisms of Food Quality Regulation

edited by Jun Yan

submission deadline 30 Nov 2026 | Viewed by 170 | Submission Open

Keywords: food quality regulation; molecular mechanism; omics technology; food macromolecules; postharvest preservation; gene transcription regulation

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms Underlying Plant Responses to Biotic and Abiotic Stress

edited by

Mohamed Ait-El-Mokhtar

and

Raja Ben-Laouane

submission deadline 30 Nov 2026 | Viewed by 168 | Submission Open

Keywords: plant stress responses; abiotic stress; biotic stress; signal transduction; multi-omics; epigenetic regulation; plant– microbe interactions; biostimulants; crop resilience

(This special issue belongs to the Section Molecular Plant Sciences)

Latest Research on Mixed Biofilms: Bacterial and Antimicrobial

edited by

Anis Rageh Mohammad Al-Maleki

submission deadline 30 Nov 2026 | Viewed by 161 | Submission Open

Keywords: antimicrobial resistance (AMR); biofilms; mixed-species biofilms; microbial interactions; anti-biofilm strategies; microbial virulence; host– pathogen interactions; microbiome; omics approaches (proteomics; genomics; metabolomics); infectious diseases

(This special issue belongs to the Section Molecular Microbiology)

Displaying special issue 2651-2700 on page 54 of 65.

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