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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Perspectives on Fish Nutrition, Physiology and Molecular Regulatory Networks

edited by Linghong Miao

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2560 | Submission Open

Keywords: fish nutrition; feed ingredients; intestinal physiology; molecular regulation; stress response and welfare; genetic mechanisms; aquaculture sustainability; omics technologies

(This special issue belongs to the Section Molecular Biology)

Molecular and Translational Research in Cardiovascular Endocrinology, Cardiovascular–Kidney–Metabolic Diseases and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): 3rd Edition

edited by

Eva Kassi

Ioannis Kyrou

and

Harpal S. S. Randeva

submission deadline 30 Nov 2026 | 3 articles | Viewed by 2535 | Submission Open

Keywords: cardiovascular endocrinology; atherosclerosis; coronary artery disease; endocrine hypertension; non-alcoholic fatty liver disease (NAFLD); diabetes mellitus and obesity; metabolic syndrome; endothelial cells; vascular inflammation; antidiabetic drugs; antihypertensive treatments; lipid lowering treatments; lifestyle interventions; molecular targeted therapies; heart failure; chronic kidney disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Plant Breeding

edited by

Hélia Cardoso

, Sandra Correia and

Isaura Castro

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2402 | Submission Open

Keywords: plant breeding; proteomics; metabolomics; epigenomics; gene editing

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Research on Crop Quality

edited by

Jinsong Bao

submission deadline 30 Nov 2026 | 3 articles | Viewed by 2368 | Submission Open

Keywords: crop quality; molecular breeding; multi-omics; gene editing; precision agriculture; functional genomics; rice; wheat; maize; barley; sorghum; millet; potato; cotton; molecular markers; genome-wide association studies; genome editing; genome selection; molecular selection; transcriptomics; omics; post-translational regulation; starch; protein; lipids; vitamin; processing quality; eating quality

(This special issue belongs to the Section Molecular Plant Sciences)

Unraveling Neuroimmune Disorders: From Pathogenic Pathways to Biomarker-Driven Precision Medicine

edited by

Mariapaola Marino

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2346 | Submission Open

Keywords: innate immunity; adaptive immunity; inflammation; autoantibodies; peptides; cytokines; receptors; leukocytes; extracellular vesicles; signal transduction; apoptosis

(This special issue belongs to the Section Molecular Immunology)

Application of Germplasm Innovation Technology in Aquactic Genetic Breeding

edited by

Hui Qiao

submission deadline 30 Nov 2026 | 3 articles | Viewed by 2337 | Submission Open

Keywords: aquaculture; biotechnology; germplasm improvement; genetic breeding; gene function; genomics; gene editing

(This special issue belongs to the Section Molecular Genetics and Genomics)

G Protein-Coupled Receptor Signaling and Regulation, 2nd Edition

edited by

Vsevolod V. Gurevich

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2284 | Submission Open

Keywords: GPCRs; signaling; trafficking; G proteins; arrestins; RGS proteins; GRKs

(This special issue belongs to the Section Biochemistry)

Computer Simulation Insight into Ligand–Receptor Interaction

edited by

Antonios Drakopoulos

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2265 | Submission Open

Keywords: structure– activity relationship (SAR); free energy perturbation (FEP); structure-based drug design (SBDD); machine learning in drug discovery; hybrid qm/mm methods; binding affinity prediction; enhanced sampling techniques; target binding kinetics

(This special issue belongs to the Section Molecular Informatics)

Recent Advances in Neurofibromatosis Type 1: From Molecular Insights to Novel Therapies

edited by László Szabó and

Márta Medvecz

submission deadline 30 Nov 2026 | 1 articles | Viewed by 2152 | Submission Open

Keywords: neurofibromatosis type 1; genotype– phenotype analyses; molecular pathogenesis; next-generation sequencing (NGS); molecular targeted therapy; MEK inhibitors; imaging studies

(This special issue belongs to the Section Molecular Neurobiology)

Natural Products as Therapeutic Agents: From Molecular Targets to Cellular and Functional Modulation

edited by Su-Yun Lyu

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2130 | Submission Open

Keywords: natural products; molecular targets; cellular modulation; functional modulation; therapeutic agents

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Molecular Insights into Antibacterial Materials

edited by Rahela Carpa

submission deadline 30 Nov 2026 | 1 articles | Viewed by 2127 | Submission Open

Keywords: antimicrobial resistance; nanoparticles; biopolymers; antimicrobial peptides; antimicrobial materials

(This special issue belongs to the Section Materials Science)

Artificial Intelligence in Molecular Biomarker Screening

edited by

Tony Hsiu-Hsi Chen

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2076 | Submission Open

Keywords: molecular biomarkers; imaging biomarkers; screening; artificial intelligence; metaverse

(This special issue belongs to the Section Molecular Informatics)

Molecular and Computational Innovations in Forensic Genetics: From Degraded DNA to Predictive Models

edited by Eugenio Alladio and

Elena Pilli

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1989 | Submission Open

Keywords: degraded DNA; low-template DNA; molecular forensics; NGS; machine learning; deep learning; chemometrics; data integration; predictive models; forensic applications

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Mechanisms of Allergy and Asthma: 4th Edition

edited by

Daniel P. Potaczek

submission deadline 30 Nov 2026 | 3 articles | Viewed by 1983 | Submission Open

Keywords: allergy; asthma; epigenetics/epigenomics; genetics/genomics; inflammation; molecular biology

(This special issue belongs to the Section Molecular Biology)

Synthesis and Application of Natural and Inspired-Natural Products

edited by Mauro de Nisco

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1919 | Submission Open

Keywords: natural products; natural substances; derivative; synthesis; application

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Cardiovascular Diseases: Histopathological and Molecular Diagnostics, 2nd Edition

edited by

Simona Gurzu

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1838 | Submission Open

Keywords: cardiovascular disorders; heart failure; aortic diseases; cardiomyocytes; cardiac function; myocarditis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cellular and Molecular Biology of Cardiac Hypertrophy and Heart Failure: Pathogenesis, Diagnostics and Treatment—2nd Edition

edited by

Morris Karmazyn

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1786 | Submission Open

Keywords: cardiac hypertrophy; myocardial remodelling; heart failure; cellular mechanisms; molecular mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Domestic Animal Genetics, Genomics, and Molecular Breeding

edited by

Ke Wang

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1750 | Submission Open

Keywords: genomic selection; molecular breeding; domestic animals; functional genomics; genetic improvement; product quality; reproduction

(This special issue belongs to the Section Molecular Genetics and Genomics)

The Anti-Inflammatory and Antioxidant Potential of Phytochemicals

edited by

Woo-Sik Jeong

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1732 | Submission Open

Keywords: phytochemicals; dietary bioactives; inflammation; natural compounds; functional foods; oxidative stress; cytokine modulation; NF-κ B signaling; chronic diseases; plant-derived metabolites

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research and Cellular Biology of Breast Cancer: 2nd Edition

edited by

Andrea Nicolini

and

Cristian Scatena

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1709 | Submission Open

Keywords: molecular mechanisms of tumor growth and diffusion; cancer cell biology; biology of tumor micro-environmental cells; MDR; hormone dependency; HER2 positive breast cancer; TNBC; genetic and epigenetic alterations; pro-tumor and anti-tumor; immune responses; conventional and biological therapies; blood and tissue biomarkers

(This special issue belongs to the Section Molecular Oncology)

Molecular Studies of Hematologic Malignancies

edited by

Myunggon Ko

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1704 | Submission Open

Keywords: hematologic malignancies; molecular mechanisms; genetic and epigenetic aberrations; molecular diagnosis; targeted therapy and biomarkers

(This special issue belongs to the Section Molecular Oncology)

Preservation of Testicular Function: From Andrological Pathologies to Testis Cancer

edited by

Elisa Dalla Pozza

and

Ilaria Dando

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1620 | Submission Open

Keywords: testicular function; male infertility; fertility preservation; spermatogenesis; oxidative stress; cell death; testicular cancer; testosterone

(This special issue belongs to the Section Molecular Pharmacology)

Precision Nutrition and Cancer: Molecular Insights into Cancer Prevention and Development

edited by

Da Pan

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1520 | Submission Open

Keywords: precision nutrition; cancer prevention; cancer development; nutrigenomics; personalized diets; tumor metabolism; dietary interventions

(This special issue belongs to the Section Molecular Oncology)

Focus on Heterocyclic Compounds and Their Various Applications

edited by

Georgia Zissimou

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1516 | Submission Open

Keywords: heterocyclic compounds; heterocyclic organic synthesis; medicinal heterocycles; bioactive heterocycles; heterocycles in materials sciences

(This special issue belongs to the Section Biochemistry)

Synthesis and Activity Studies of Anticancer Compounds

edited by Agata Pacuła-Miszewska

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1496 | Submission Open

Keywords: anticancer agents; structure-activity relationship; cytotoxicity mechanisms; medicinal chemistry; drug design

(This special issue belongs to the Section Molecular Pharmacology)

Microbiota-Mediated Regulation of Stem Cells in Cancer Initiation, Progression, and Treatment Response

edited by

Ciro Gargiulo Isacco

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1475 | Submission Open

Keywords: microbiota stem cell cancer

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

X-Linked Disorders: Epigenetic and Environmental Modulation of Phenotypes

edited by Yoram Chaiter and

Yossy Machluf

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1410 | Submission Open

Keywords: X-linked disorders; epigenetics; environmental factors; gene expression; clinical manifestations

(This special issue belongs to the Section Molecular Genetics and Genomics)

Innovations in Analytical Chemistry for Environmental and Food Safety: Methodologies and Molecular Insights

edited by

Cosima Damiana Calvano

and

Francesco Longobardi

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1410 | Submission Open

Keywords: innovative sample preparation; food quality and safety; advanced analytical techniques; risk assessment

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Advances in the Molecular Pathogenesis of Gastrointestinal Malignancies with Implications for Diagnosis and Therapy

edited by Laura Necula

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1409 | Submission Open

Keywords: gastrointestinal cancers; biomarkers; early diagnosis; circulating molecules; non-invasive tests

(This special issue belongs to the Section Molecular Oncology)

Advances in Metalloproteinase, 2nd Edition

edited by

Kyu-Yeon Han

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1401 | Submission Open

Keywords: matrix metalloproteinases (MMPs); substrate specificity; pathological condition; metalloproteinases inhibitors

(This special issue belongs to the Section Biochemistry)

The Role of Melatonin in Plants: 3rd Edition

edited by

Małgorzata M. Posmyk

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1396 | Submission Open

Keywords: melatonin; phytomelatonin; plants; seed germination; seasonal and circadian rhythms; flowering; fruit ripening; plant immunity; abiotic stresses

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanism and Pharmacological Target of Neuroprotection

edited by

Pietro Cacialli

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1369 | Submission Open

Keywords: neurodegeneration; animal model; brain regeneration; pharmacological drug; molecular analysis

(This special issue belongs to the Section Molecular Neurobiology)

Latest Advances on Natural Bioactive Molecules and Polysaccharides

edited by Loredana Marcolongo

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1312 | Submission Open

Keywords: natural products; bioactive compounds; polysaccharides; extraction technologies; bioprocesses; value-added products; one-health

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Dietary Interventions for Type 2 Diabetes: Current Evidence and Emerging Perspectives on Underlying Molecular Mechanisms

edited by Caterina Formichi

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1305 | Submission Open

Keywords: type 2 diabetes; nutritional intervention; dietary strategies; nutrients; personalized nutrition; diet; metabolic health

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Current Advances in the Pathophysiology and Treatment of Multiple Sclerosis and Related Disorders

edited by Natalia Szejko and

Sara Samadzadeh

submission deadline 30 Nov 2026 | Viewed by 1304 | Submission Open

Keywords: multiple sclerosis; MS; central nervous system; pathophysiology; immunological system

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Unveiling Molecular Mysteries of Brain Barriers

edited by Ana Catarina Duarte

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1297 | Submission Open

Keywords: blood– brain barrier; blood– cerebrospinal fluid barrier; arachnoid barrier; transport mechanisms; drug delivery; drug metabolism; ATP-binding cassete (ABC) transporters

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms of Skeletal Muscle Adaptation

edited by

Michele Salanova

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1280 | Submission Open

Keywords: skeletal muscle; adaptive responses; muscle physiology; genomics; transcriptomics; proteomics; molecular mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Extracellular Vesicles—New Findings on the Block in Liquid Biopsy

edited by Christa Nöhammer

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1260 | Submission Open

Keywords: extracellular vesicles; biological fluids; liquid biopsy; multi-omics; biomarkers; EV technologies

(This special issue belongs to the Section Molecular Biology)

Ligament/Tendon and Cartilage Tissue Engineering and Reconstruction, 2nd Edition

edited by

Clemens Gögele

and

Gundula Schulze-Tanzil

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1240 | Submission Open

Keywords: cartilage; tendon; ligament; anterior cruciate ligament; bioprinting; scaffold; bioreactor; tissue engineering

(This special issue belongs to the Section Molecular Biology)

AI, ML and Bioinformatics in Molecular Mechanisms of Human Health and Disease

edited by

Santosh Anand

submission deadline 30 Nov 2026 | 3 articles | Viewed by 1194 | Submission Open

Keywords: artificial intelligence; machine learning; bioinformatics; molecular mechanisms; human health; human disease; multi-omics data; molecular pathways; personalized medicine; disease biomarkers

(This special issue belongs to the Section Molecular Informatics)

Regenerative Medicine: Biomaterials and Stem Cell Research: 2nd Edition

edited by Silvia María Díaz-Prado

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1148 | Submission Open

Keywords: regenerative medicine; stem cell; biomaterial; bioprinting; tissue engineering; tissue and organ transplant; organ scarcity

(This special issue belongs to the Section Materials Science)

New Insights in Antibiotic Resistance/Tolerance

edited by

Mara Di Giulio

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1139 | Submission Open

Keywords: antibiotic resistance; biofilm; innovative antimicrobial strategies and compounds; synergistic actions; One Health; bacterial tolerant phenotypes; resistant pathogenic microorganisms; mechanisms of antimicrobial resistance

(This special issue belongs to the Section Molecular Microbiology)

Viral Infections and Cancer: Recent Advances and Future Perspectives (2nd Edition)

edited by

Nabiha Yusuf

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1124 | Submission Open

Keywords: virus; infection; cancer; immune response

(This special issue belongs to the Section Molecular Oncology)

Molecular Studies in Gynecological Oncology: Advancing Diagnosis and Treatment

edited by

Ivonne Nel

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1105 | Submission Open

Keywords: biomarker; cancer screening; clinical trial; DNA repair; invasion; metastasis; methylation; molecular diagnostics; molecular tumor pathology; next-generation sequencing; omics; personalized medicine; prognosis; single-cell analysis; targeted therapy; translational cancer research; treatment response; tumor microenvironment

(This special issue belongs to the Section Molecular Oncology)

Molecular Research of Cardiovascular Disease

edited by

John A. St. Cyr

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1102 | Submission Open

Keywords: myocardium; metabolism; ischemia; function; integrity; cardiovascular; disease; infarction; failure

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Advances in Bioactive Compounds

edited by

Samuel Cota Teixeira

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1057 | Submission Open

Keywords: bioactive compound; natural products; polyphenols; carotenoids; alkaloids

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Mechanisms of RNA Interactions and Biomarker Discovery for Human Diseases

edited by

Lei Wang

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1024 | Submission Open

Keywords: biomarker discovery; RNA interactions; RNA– disease associations; drug– RNA interactions; therapeutic targets

(This special issue belongs to the Section Molecular Informatics)

Application of Natural Products in Biomedicine and Pharmacotherapy: 3rd Edition

edited by

George Miloshev

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1021 | Submission Open

Keywords: natural products; biomedicine; genotoxicity; epigenetics; aging

(This special issue belongs to the Section Molecular Pharmacology)

Unraveling the Molecular Landscape of Primary Brain Tumors

edited by

Giuseppe Lombardi

, Francesco Pasqualetti and Tamara Ius

submission deadline 30 Nov 2026 | Viewed by 1002 | Submission Open

Keywords: primary brain tumors; molecular oncology; glioma; glioblastoma; biomarkers; targeted therapy; epigenetics; tumor microenvironment; genomic profiling; translational research

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Biomarkers in Mood Disorders

edited by Lionella Palego and

Valerio Dell’Oste

submission deadline 30 Nov 2026 | 1 articles | Viewed by 988 | Submission Open

Keywords: mood disorders; etiopathogenesis; genetics/epigenetics; RNA analyses; neuroendocrinology; inflammation; molecular markers

(This special issue belongs to the Section Molecular Neurobiology)

Displaying special issue 2651-2700 on page 54 of 65.

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