Radiobiology: New Challenges and Advances
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 1
Special Issue Editors
Interests: hadrontherapy; radiation-induced cytogenetic damage; normal-tissue radioprotection and cancer radiosensitization; combined cancer treatments; novel temporal regimes
Interests: radiobiological effects of laser-induced radiation; enhancement of proton therapy effectiveness; effects of heavy and high-energy particles; ultra-high dose rate sparing of normal tissue; cytogenetic damage and genomic instability
Special Issue Information
Dear Colleagues,
We invite you to contribute to this Special Issue on new challenges in radiobiology. The contribution radiobiology has made to the promotion of human health is exemplified by the wealth of knowledge it has generated in cancer radiotherapy (RT), using ever-evolving enhancements from fields such as physics, chemistry, and molecular biology. However, radiobiology is far from having exhausted its propulsive force and still has a fundamental role to play by harnessing technological advances, such as unexplored temporal regimes or artificial intelligence. Moreover, a renewed interest in combined modality treatments, such as BNCT, or the need for a standardised approach—from advanced microdosimetry to Monte Carlo-based simulations—to accurately match physical parameters with biological responses, demands updated radiobiological workflows Finally, topics such as the systemic responses elicited by radiation or 3D/novel in vitro study models (spheroids and organ-on-a-chip technology) all invoke new radiobiological trends.
This Special Issue, “Radiobiology: New Challenges and Advances”, will, therefore, focus on this “new radiobiology” and will include original research and provocative review articles.
Prof. Dr. Lorenzo Manti
Dr. Pavel Bláha
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- strategies for overcoming cancer radioresistance and normal-tissue damage mitigation
- combined approaches: BNCT, proton–boron capture therapy, radioimmunotherapy
- emerging technologies and novel temporal regimes: FLASH RT mechanisms and radiobiology of laser-accelerated particles
- radiobiology of new ions and of novel dose-delivery modalities in particle radiotherapy
- limphopoenia in radiotherapy and biomarkers of radiation response
- three-dimensional models
- microdosimetry: standardising measurements
- DNA damage/repair
- tumour microenvironment: autophagy, ferroptosis, fibroblast activation protein
- non-cancer effects and non-targeted effects
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
