Radiobiology: New Challenges and Advances
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 November 2026 | Viewed by 769
Special Issue Editors
Interests: hadrontherapy; radiation-induced cytogenetic damage; normal-tissue radioprotection and cancer radiosensitization; combined cancer treatments; novel temporal regimes
Interests: radiobiological effects of laser-induced radiation; enhancement of proton therapy effectiveness; effects of heavy and high-energy particles; ultra-high dose rate sparing of normal tissue; cytogenetic damage and genomic instability
Special Issue Information
Dear Colleagues,
We invite you to contribute to this Special Issue on new challenges in radiobiology. The contribution radiobiology has made to the promotion of human health is exemplified by the wealth of knowledge it has generated in cancer radiotherapy (RT), using ever-evolving enhancements from fields such as physics, chemistry, and molecular biology. However, radiobiology is far from having exhausted its propulsive force and still has a fundamental role to play by harnessing technological advances, such as unexplored temporal regimes or artificial intelligence. Moreover, a renewed interest in combined modality treatments, such as BNCT, or the need for a standardised approach—from advanced microdosimetry to Monte Carlo-based simulations—to accurately match physical parameters with biological responses, demands updated radiobiological workflows Finally, topics such as the systemic responses elicited by radiation or 3D/novel in vitro study models (spheroids and organ-on-a-chip technology) all invoke new radiobiological trends.
This Special Issue, “Radiobiology: New Challenges and Advances”, will, therefore, focus on this “new radiobiology” and will include original research and provocative review articles.
Prof. Dr. Lorenzo Manti
Dr. Pavel Bláha
Guest Editors
Manuscript Submission Information
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Keywords
- strategies for overcoming cancer radioresistance and normal-tissue damage mitigation
- combined approaches: BNCT, proton–boron capture therapy, radioimmunotherapy
- emerging technologies and novel temporal regimes: FLASH RT mechanisms and radiobiology of laser-accelerated particles
- radiobiology of new ions and of novel dose-delivery modalities in particle radiotherapy
- limphopoenia in radiotherapy and biomarkers of radiation response
- three-dimensional models
- microdosimetry: standardising measurements
- DNA damage/repair
- tumour microenvironment: autophagy, ferroptosis, fibroblast activation protein
- non-cancer effects and non-targeted effects
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