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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Intestinal 3D Culture, Organoids and Gut-on-Chip in Intestinal Disorders

edited by

Vanessa D’Antongiovanni

and

Carolina Pellegrini

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2385 | Submission Open

Keywords: 3D cultures; gut-on-chip; intestinal organoids; spheroids; organotypic cultures; morphological studies; pharmacological studies; intestinal cancer; inflammatory bowel disease; intestinal functional disorders

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Adsorbing Materials

edited by Mounia Achak

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2356 | Submission Open

Keywords: adsorption process; adsorbing materials; bio-based adsorbents; regeneration and reusability; pollutant removal; wastewater treatment; industrial and environmental applications

(This special issue belongs to the Section Materials Science)

Molecular Associations Between Adipose Tissue and Diseases

edited by

Roberto Cannataro

Erika Cione

and

Maria Cristina Caroleo

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2301 | Submission Open

Keywords: lipedema; adipose tissue; adipocyte; adipose organ; body fat; miRNA; ketogenic diet

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Biology of Lung Cancer: From Intrinsic to Acquired Resistance Mechanisms

edited by

Federico Pio Fabrizio

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2295 | Submission Open

Keywords: lung cancer; NSCLC; cancer therapy; resistance; DNA methylation

(This special issue belongs to the Section Molecular Oncology)

Environmental Heavy Metals with Their Benefits and Risks for Human Health

edited by

Rolf Teschke

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2274 | Submission Open

Keywords: heavy metals; metal compound; iron; copper; cadmium; arsenic; oxidative stress; cell death; toxicology; Wilson disease; hemochromatosis

(This special issue belongs to the Section Molecular Toxicology)

Pathophysiological Insights, Biomarkers and New Therapeutic Strategies in Immune-Mediated Disorders and Neurodegenerative Diseases

edited by

Eleonora Virgilio

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2252 | Submission Open

Keywords: neurodegeneration; neuroimmunology; inflammation; biomarkers; treatment; pathophysiology; multiple sclerosis; myasthenia gravis; neurodegenerative disease

(This special issue belongs to the Section Molecular Immunology)

Stem Cells Research: Advancing Science and Medicine

edited by Susana Rosa

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2218 | Submission Open

Keywords: stem cell; stem cell biology; stem cell-based therapies; regenerative medicine; disease modeling

(This special issue belongs to the Section Biochemistry)

Zebrafish: A Model Organism for Human Health and Disease: 2nd Edition

edited by

Jyotshna Kanungo

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2181 | Submission Open

Keywords: zebrafish; drug discovery; high-throughput screens; genome editing/CRISPR mutants; cancer; neuronal disorders; drug toxicity; drug effect mechanisms; developmental disorders

(This special issue belongs to the Section Molecular Biology)

Advances in Metabolic Phenotypes of Pediatric Obesity

edited by Simona Georgiana Popa

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2179 | Submission Open

Keywords: cardiometabolic phenotypes of pediatric obesity; metabolomic profiles; microbiota; entero-insular axis; adipocytokines; precision therapy

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

New Insights into the Antibacterial Effect of Nano- and Micro-Materials

edited by

Krasimir Vasilev

and

Vi Khanh Truong

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2172 | Submission Open

Keywords: antibacterial coatings; biomaterials; medical devices; antimicrobial resistance; nanomedicine

(This special issue belongs to the Section Materials Science)

Molecular Mechanisms and Functions of Extracellular Vesicles

edited by

Sigrun Lange

and Jameel M. Inal

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2136 | Submission Open

Keywords: extracellular vesicles; molecular mechanisms; biomarkers; liquid biopsy; cell-communication; cellular function; pathobiology; clinical

(This special issue belongs to the Section Molecular Biology)

The Impact of Biomolecules on the Pathogenesis of Oral and Periodontal Diseases

edited by

Ujjal Kumar Bhawal

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2117 | Submission Open

Keywords: biomolecules; inflammatory mediators; enzymes; cytokines; dysbiosis; microbiome; genetic and epigenetic factors; oral and periodontal diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Micropollutants in Various Enviroments

edited by

Anna Lenart-Boroń

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2075 | Submission Open

Keywords: airborne microorganisms; antibiotics; antibiotic resistance; circular economy of water; environmental bacteria and fungi; wastewater treatment; waterborne microorganisms; water quality

(This special issue belongs to the Section Molecular Toxicology)

Advanced Molecular Research in Brain Tumors

edited by

Shiv K. Gupta

submission deadline 20 Feb 2026 | 3 articles | Viewed by 2063 | Submission Open

Keywords: targeted therapy; blood– brain barrier; GBM; glioma; immune checkpoint blockers; TME

(This special issue belongs to the Section Molecular Oncology)

Protein Kinase in Disease, 2nd Edition

edited by

Manae Suzuki Kurokawa

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2005 | Submission Open

Keywords: protein kinases; phosphorylation; cancers; inflammatory diseases; protein kinase inhibitors; anticancer drugs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Therapeutic Targets in Cardiometabolic Disorders

edited by Massimiliano M. Corsi Romanelli and

Pietro Formisano

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2001 | Submission Open

Keywords: atherosclerosis; angiotensin; endothelial cell; inflammation; biomarkers; gLP-1; sT-2

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Diagnosis and Treatment of Migraine

edited by

Fabiola Dach

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1945 | Submission Open

Keywords: migraine; pathophysiology; diagnostics; therapy; molecular mechanisms

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms of Phytochemicals in Antioxidation, Antimicrobial, and Cytoprotective Properties

edited by

Mihaela Niculae

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1914 | Submission Open

Keywords: phytochemicals; antioxidant; antimicrobial; cytoprotective; in vitro screening; in vivo evaluation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Insights into Heart Failure: From Bench to Bedside

edited by

Nadia Aspromonte

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1887 | Submission Open

Keywords: heart failure; cardiac biomarkers; medical therapy; molecular pathways; prognosis; target therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Acute Kidney Injury: Molecular Mechanism and Targeted Therapeutic Approaches

edited by

Bin Yang

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1823 | Submission Open

Keywords: kidney injury; repair; immunoresponse; biomarker; targeted therapy; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Pathogenesis and Treatment of Skin Cancer (2nd Edition)

edited by

Enrica Flori

Giorgia Cardinali

and

Vittoria Maresca

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1802 | Submission Open

Keywords: melanoma; squamous cell carcinoma; basal cell carcinoma; tumor microenvironment; epithelial– mesenchymal transition (EMT) process; ultraviolet radiation; oxidative stress; bioactive modulators; signal transduction pathways

(This special issue belongs to the Section Molecular Oncology)

Plant Metabolism and Natural Product Biosynthesis

edited by

Andrej Frolov

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1794 | Submission Open

Keywords: plant metabolism; natural product; biosynthesis; metabolomics; bioinformatics

(This special issue belongs to the Section Molecular Plant Sciences)

Exploring the Genetics in Rare Diseases: A Genomic Odyssey

edited by

Klaus Brusgaard

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1771 | Submission Open

Keywords: novel discoveries in rare disorders; polygenic risk scores; mosaicism; protein interaction; tools utilized to engineer DNA; somatic variants; patient advocacy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Dyslipidemia

edited by

Aleksandra Zeljkovic

and

Jelena Vekić

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1746 | Submission Open

Keywords: dyslipidemia; chronic non-communicable diseases; dysregulation of lipid homeostasis; genetic and epigenetic regulation; lipidomics in personalized medicine; lipid biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Developing Chiral Products: New Progression in Separation, Synthesis, and Application

edited by István Ilisz

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1734 | Submission Open

Keywords: chirality; enantioselective separations; chiral selector molecules; chiral stationary phases; chiral sensors; enantiorecognition; chiral separation mechanisms

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

The Diversity of Life: Light to Heavy Metal Coordination Compounds of Biological Relevance

edited by

Ivayla Pantcheva

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1705 | Submission Open

Keywords: coordination compounds; metal-based drugs; antimicrobial; anti-inflammatory; antiviral agents; cancer therapy; drug delivery systems

(This special issue belongs to the Section Biochemistry)

New Advances in Cystinosis from Basic to Clinical Research

edited by Francesco Bellomo

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1684 | Submission Open

Keywords: cystinosis; kidney; Fanconi syndrome; muscles; eyes; autophagy; bioenergetics; inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Ruminant Physiology: Digestion, Metabolism, and Endocrine System

edited by Rui Hu

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1656 | Submission Open

Keywords: ruminant physiology; digestive health; metabolic regulation; endocrine signaling; rumen microbiome; nutrient partitioning; methane mitigation; epigenetic modulation; nutritional stress adaptation

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Toxicological Impacts of Emerging Contaminants on Aquatic Organisms

edited by

Mohamed Hamed

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1624 | Submission Open

Keywords: aquatic toxicology; emerging contaminants; physiology and behavior; oxidative stress; antioxidant biomarkers; immunotoxicity; neuroendocrine toxicity; bioremediation; molecular mechanisms

(This special issue belongs to the Section Molecular Toxicology)

Advancing Liver Health: State of the Art and Recent Research Advances

edited by

Chase Wehrle

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1602 | Submission Open

Keywords: liver; liver cancer and malignancy; liver transplantation; inflammation and immunity; liver health and ageing; molecular genomics; cellular senescence; metabolic dysfunction-associated liver disease; cirrhosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Biology of Periodontal Disease and Periodontal Pathogens

edited by Yago Leira and

João Botelho

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1584 | Submission Open

Keywords: periodontitis; general medicine; inflammation; bacteraemia; education

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Gynecological Oncology: From Molecular Basis to Therapy

edited by

Martin Götte

and Lars Hanker

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1558 | Submission Open

Keywords: gynecological oncology; molecular basis; targeted therapy; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Molecular Insights into the Role of Exercise in Disease and Health, 2nd Edition

edited by

Brisamar Estébanez

, María José Cuevas-González and Chun-Jung Huang

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1553 | Submission Open

Keywords: physical activity; molecular mechanisms; disease prevention; metabolic health; cardiovascular diseases; neurodegenerative diseases; sarcopenia; immune function; healthy aging; epigenetics

(This special issue belongs to the Section Molecular Biology)

Research on Alloy Materials Microstructure and Their Functionalization

edited by

Ozkan Gokcekaya

and Celaletdin Ergun

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1538 | Submission Open

Keywords: alloy design; microstructure; production methods; additive manufacturing; sol– gel process; biofunctional materials; magnetic properties; nanoparticles; ceramics; composites

(This special issue belongs to the Section Materials Science)

Molecular Mechanisms of Tumorigenesis of Human and Animal Stem Cells

edited by

Daniela Salvatori

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1528 | Submission Open

Keywords: malignancy; stem cells; safety; chromosal aberrations; animal; human; teratoma assay; in vitro assays

(This special issue belongs to the Section Molecular Oncology)

Bioactive Natural Compounds in Neuroscience

edited by

Sarmistha Mitra

submission deadline 20 Feb 2026 | Viewed by 1525 | Submission Open

Keywords: natural products; bioactive metabolites; secondary metabolites; neuronal development; neurotrophins; neuromedicine; neurodegeneration; memory disorders

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research on Parasitic Infection

edited by Marcin Wiśniewski and

Piotr Bąska

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1451 | Submission Open

Keywords: parasitic infections; host– parasite interactions; parasite genomics; drug-resistance mechanisms; transcriptomics; proteomics; diagnostic tools; immune evasion; therapeutic strategies

(This special issue belongs to the Section Molecular Microbiology)

Biomechanics and Molecular Research on Glioblastoma: 2nd Edition

edited by

Lorenzo Corsi

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1427 | Submission Open

Keywords: GBM; molecular pathways; biomechanics; oncogene; cancer; microenvironment; drug targeting; diagnostic; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Molecular Research and Insight in Neurotransmission and Neuromodulation

edited by Miklos Jaszberenyi

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1423 | Submission Open

Keywords: histology; microanatomy; morphology; molecular biology; neurotransmitter; neuromodulator; neuropeptide; neurohormone; nervous system

(This special issue belongs to the Section Molecular Neurobiology)

Harnessing Bioinformatics for miRNA Research: Methods, Insights and Applications

edited by Maria Rosaria Tumolo and Saverio Sabina

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1414 | Submission Open

Keywords: microRNA; bioinformatics; hub genes; miRNA target prediction; miRNA regulatory networks; miRNA-based biomarkers; artificial intelligence in miRNA research; multi-omics approaches

(This special issue belongs to the Section Molecular Informatics)

Molecular Mechanisms and Therapeutic Strategies of Colorectal Cancer

edited by

Daniel Gabriel Pons

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1411 | Submission Open

Keywords: colorectal cancer; tumor microenvironment; biomarkers; intercellular communication; therapeutic strategies

(This special issue belongs to the Section Molecular Oncology)

Advances in Vitiligo: From Mechanisms to Treatment Innovations

edited by Hyun Jeong Ju

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1383 | Submission Open

Keywords: autoimmune disease; cytokine signaling; depigmentation; immunotherapy; melanocyte regeneration; microbiome; oxidative stress; vitiligo

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Interactions and Advanced Computational Methods for Biomolecular Systems

edited by

Amar Singh

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1376 | Submission Open

Keywords: molecular interactions; biological systems; computational biology; protein– protein interactions; protein docking; bioinformatics; structural modeling; multiscale modeling techniques

(This special issue belongs to the Section Molecular Biophysics)

The Plant Cell Wall: Structural Dynamics, Functions, and Future Innovations

edited by

Ioannis-Dimosthenis Adamakis

and

Kosmas Haralampidis

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1372 | Submission Open

Keywords: plant cell wall; biosynthesis; biomass; abiotic stress; biotic stress; renewable resources; biotechnology; climate change

(This special issue belongs to the Section Molecular Plant Sciences)

Advanced Research on Plant-Derived Products in the Service of Immune Regulation

edited by

Lyuba Dineva Miteva

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1351 | Submission Open

Keywords: plant bioactive compound; inflammation; immunity; cytokine; chronic disease

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Mechanisms and Neural Circuits in Behavioral Neuroscience

edited by Matteo Di Segni and Rossella Ventura

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1328 | Submission Open

Keywords: behavioral neuroscience; neural circuits; psychopathology; neuroscience; drug addiction; depression; mental illness

(This special issue belongs to the Section Molecular Neurobiology)

Microbiome-Immunity Crosstalk and Its Role in Health and Disease

edited by

Ana Isabel Beltrán-Velasco

and Sara Uceda

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1317 | Submission Open

Keywords: gut microbiota; immune system; nutrition; inflammatory processes; dysbiosis; neurodegenerative diseases

(This special issue belongs to the Section Molecular Microbiology)

The Toxicity of Bisphenol A and Its Analogs

edited by

Krystyna Makowska

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1228 | Submission Open

Keywords: bisphenols; endocrine disruptors; bisphenol A and analogs; toxicology

(This special issue belongs to the Section Molecular Toxicology)

Study on the Microenvironment in Lymphoma

edited by

Jonathan P. Butchar

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1201 | Submission Open

Keywords: tumor microenvironment; lymphoma; hodgkin lymphoma; non-hodgkin lymphoma; burkitt lymphoma; follicular lymphoma; waldenströ m’ s macroglobulinemia; NK/T-cell lymphoma; diffuse large B-cell lymphoma; mantle cell lymphoma; marginal zone lymphoma; lymphoproliferative disorder; anaplastic large cell lymphoma; mediastinal B cell lymphoma; T-cell lymphomas

(This special issue belongs to the Section Molecular Oncology)

Novel Insights into Buckwheat Reproductive Biology

edited by

Agnieszka Płażek

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1170 | Submission Open

Keywords: antioxidant properties; biotechnological methods; embryology; seed chemical composition; yield

(This special issue belongs to the Section Molecular Plant Sciences)

Displaying special issue 1451-1500 on page 30 of 66.

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