Acute Kidney Injury: Molecular Mechanism and Targeted Therapeutic Approaches
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 157
Special Issue Editor
Interests: acute kidney injury; repair; biomarker; immunoresponse; targeted therapy; precision medicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Acute kidney injury (AKI) is a critical illness with a high mortality rate and often progresses to chronic kidney disease, without cause-specific treatment. It is imperative to understand the mechanisms of AKI and its chronic progression in order to identify potential biomarkers for early diagnosis, intervention, and monitoring prognosis. In particular, gene therapy, including siRNA, specifically silencing target genes via complimentary sequences, has been studied in numerous disease models, with some agents/approaches developing into clinical trials. However, delivering gene-modifying agents to the desired cells has proved to be very challenging.
We invite colleagues in the field to share their updated knowledge, research data, and unique experiences related to the above themes by submitting review papers, original research articles, or case reports to this Special Issue, entitled “Acute Kidney Injury: Molecular Mechanism and Targeted Therapeutic Approaches”, of the International Journal of Molecular Sciences. Preclinical studies will form the basis for potential human applications in native AKI and transplant kidney injury to limit injury, promote repair, and prevent chronic progression in order to improve the outcome of kidney disease and the care of kidney patients. Intervention principles and validated methods in different research projects will also be applicable to a broad range of genes and organs to facilitate precision medicine.
Prof. Dr. Bin Yang
Guest Editor
Manuscript Submission Information
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Keywords
- kidney injury
- repair
- immunoresponse
- biomarker
- targeted therapy
- precision medicine
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