Advancements in the Diagnosis and Treatment of Inflammatory Bowel Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 1347

Special Issue Editor


E-Mail Website
Guest Editor
Gastroenterologisches Zentrum, 70435 Stuttgart, Germany
Interests: ulcerative colitis; Crohn's disease; inflammatory bowel disease

Special Issue Information

Dear Colleagues,

The global burden of inflammatory bowel diseases is on the rise. Although pathophysiological mechanisms have been elucidated and new therapeutic options have expanded in the last 10 years, morbidity in terms of late damages of the bowel as well as impaired quality of life is still high. This applies especially for the diagnosis and treatment of extraintestinal manifestations (EIMs), e.g., of the liver or joints as well as cardiac complications through years of systemic inflammatory activity.

Therefore, this Special Issue has the aim to explore the latest advancements in the diagnosis and treatment of chronic inflammatory bowel diseases (IBDs). Emphasizing innovative diagnostic techniques, this issue dives into imaging modalities, biomarker identification, scoring quality of life, diagnostic work-ups of EIMs, and the utilization of endoscopic advancements to enhance diagnostic accuracy. A critical focus is placed on evaluating therapeutic responses, with discussions on personalized medicine approaches, biologic treatments, and novel small molecules. This series will also examine the integration of artificial intelligence (AI) in predicting disease course, optimizing treatment plans, and improving patient outcomes. Additionally, the impact of IBD on patients' quality of life will be addressed, with insights into comprehensive management strategies that address both physical and psychological aspects of the disease.

A combination of original articles as well as review articles will provide an overview of current and emerging practices in the management of IBD. By highlighting these aspects, this issue aims to inform healthcare professionals about the potential benefits and challenges of these innovations, hopefully contributing to improved patient care and quality of life for those affected by chronic inflammatory bowel diseases.

Dr. Thomas Klag
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chronic inflammatory bowel diseases (IBD)
  • Crohn's disease (CD)
  • ulcerative colitis (UC)
  • therapy monitoring
  • extraintestinal manifestations (EIMs)
  • quality of life
  • artificial intelligence (AI)
  • personalized medicine
  • personalized medicine
  • endoscopic advancements

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Other

11 pages, 532 KiB  
Systematic Review
Analysis of the Incidence of Ocular Extraintestinal Manifestations in Inflammatory Bowel Disease Patients: A Systematic Review
by Bruno Songel-Sanchis and Jesús Cosín-Roger
Diagnostics 2024, 14(24), 2815; https://doi.org/10.3390/diagnostics14242815 - 14 Dec 2024
Viewed by 882
Abstract
Background: Inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis, primarily affects the gastrointestinal tract. Additionally, extraintestinal manifestations may occur in the liver, musculoskeletal system and eyes. Its etiology remains unknown, and further research is required in order to develop [...] Read more.
Background: Inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis, primarily affects the gastrointestinal tract. Additionally, extraintestinal manifestations may occur in the liver, musculoskeletal system and eyes. Its etiology remains unknown, and further research is required in order to develop pharmacological drugs which achieve complete remission of the pathology. Objective: The aim of this study was to analyze the incidence of ocular extraintestinal manifestations in IBD patients. Methods: A total of six searches were carried out on the medical publication server “PubMed” in June and July 2024, using different keywords; a total of 323 results were obtained, of which 34 were finally selected for study. Results: Ocular extraintestinal manifestations in IBD patients are more common in the anterior pole of the eye, with uveitis, scleritis and episcleritis being the most usual ones. In the case of the posterior pole, the most common manifestations are posterior uveitis and optic neuritis. Conclusions: The incidence of ocular complications whose origin is inflammatory, such as uveitis, scleritis, episcleritis and neuritis, is higher than that of complications of non-inflammatory origin. Full article
Show Figures

Figure 1

Back to TopTop