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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Inhibitors in Thyroid Carcinoma (2nd Edition) submission deadline 24 May 2026 | Viewed by 346 | Submission Open
Keywords: thyroid carcinoma; immune checkpoint inhibitors; tyrosine kinase inhibitors; sorafenib; lenvatinib
(This special issue belongs to the Section Tumor Microenvironment)
Study on Acute Myeloid Leukemia
edited by Olga K. Weinberg
submission deadline 25 May 2026 | 4 articles | Viewed by 11612 | Submission Open
Keywords: acute myeloid leukemia (AML); cancer treatment; genetic
(This special issue belongs to the Section Cancer Therapy)
Clinical Advances and State-of-the-Art Management in Genitourinary Cancers
edited by and Adnan Fazili
submission deadline 25 May 2026 | 2 articles | Viewed by 7455 | Submission Open
Keywords: genitourinary malignancies; tumor– immune microenvironment (TIME); tumor biology; genomic characterization; targeted drug therapy; immunotherapy
(This special issue belongs to the Section Clinical Research of Cancer)
Colorectal Cancer: Risk Factors and Underlying Mechanisms
edited by David Achaintre
submission deadline 25 May 2026 | 1 articles | Viewed by 2395 | Submission Open
Keywords: colorectal cancer; diet; environmental factors; microbiome; inflammation
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Primary and Recurrent Gynecological Cancer: Epidemiology, Management and New Therapies
edited by Nithya Ratnavelu and Ioannis Biliatis
submission deadline 28 May 2026 | 4 articles | Viewed by 12548 | Submission Open
Keywords: ovarian cancer; endometrial cancer; cervical cancer; vulva cancer; vaginal cancer; gynecological cancer
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Combination Therapy in Geriatric Population with Cancer (2nd Edition)
edited by
submission deadline 28 May 2026 | 3 articles | Viewed by 5969 | Submission Open
Keywords: older patients with cancer; surgery; radiotherapy; chemotherapy; immunotherapy; targeted therapy
(This special issue belongs to the Section Cancer Therapy)
New Approaches in Radiotherapy for Cancer
edited by Dandan Zheng, Alexander Podgorsak and Olga Maria Dona Lemus
submission deadline 30 May 2026 | 27 articles | Viewed by 117398 | Submission Open
Keywords: adaptive radiotherapy; FLASH; artificial intelligence; SFRT; particle therapy; proton therapy; SRS; SBRT; HDR; 3D printing; immuno-radiotherapy; radiogenmics
(This special issue belongs to the Section Cancer Therapy)
Skin Cancer Prevention: Strategies, Challenges and Future Directions
edited by Véronique del Marmol, Mariano Suppa, Ana-Maria Forsea and Alexander Stratigos
submission deadline 30 May 2026 | 8 articles | Viewed by 12767 | Submission Open
Keywords: skin cancer prevention; photoprotection; early detection; screening; epidemiology; public health; behavioral interventions; sun exposure; artificial intelligence; risk factors
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Advances in the Surgical Treatment of Spinal Tumors
edited by Daniel Lubelski
submission deadline 30 May 2026 | 4 articles | Viewed by 7424 | Submission Open
Keywords: spinal tumors; spinal metastases; minimally invasive spine surgery; radiosurgery; histology-specific treatment; prognostic modeling; machine learning; deep learning; spinal reconstruction; quality of life
(This special issue belongs to the Section Cancer Therapy)
Endoscopic Management of Pancreatic Neoplasms (2nd Edition)
edited by
submission deadline 30 May 2026 | 2 articles | Viewed by 6622 | Submission Open
Keywords: pancreatic cancer; pancreatic neoplasm; endoscopic retrograde cholangiopancreatography; endoscopic ultrasound; fine needle aspiration/biopsy; local treatment; biliary stent; biliary drainage; contrast enhancement
(This special issue belongs to the Section Methods and Technologies Development)
Advances in the Diagnosis and Treatment of Prostate Cancer: From Biomarkers to Precision Surgery
edited by Stamatios N. Katsimperis and
submission deadline 30 May 2026 | 6 articles | Viewed by 5613 | Submission Open
Keywords: prostate cancer; precision medicine; molecular biomarkers; risk stratification; robotic surgery; artificial intelligence; genomics; personalized treatment; imaging modalities; multidisciplinary approach
(This special issue belongs to the Section Cancer Therapy)
Genetics of Ovarian Cancer (2nd Edition) submission deadline 30 May 2026 | 2 articles | Viewed by 2853 | Submission Open
Keywords: epithelial ovarian cancer; genomics; epigenetics; translational research; biomarkers; DNA damage response; PARP inhibitors
(This special issue belongs to the Section Cancer Pathophysiology)
New and Future Focused Therapies for Thyroid Cancer
edited by , Poupak Fallahi, Silvia Martina Ferrari and Giusy Elia
submission deadline 30 May 2026 | 1 articles | Viewed by 2829 | Submission Open
Keywords: aggressive differentiated thyroid carcinoma; anaplastic thyroid cancer; tyrosine kinase inhibitors; immunotherapy; personalized medicine
(This special issue belongs to the Section Cancer Therapy)
Current Advances in Management of Neuroendocrine Neoplasms
edited by Ashley Kieran Clift and
submission deadline 30 May 2026 | 1 articles | Viewed by 2501 | Submission Open
Keywords: neuroendocrine tumours; epidemiology; clinical prediction models; machine learning; personalised medicine; novel biomarkers; diagnostics; treatment; artificial intelligence
(This special issue belongs to the Section Cancer Therapy)
Liquid Biopsy for Lung Cancer Treatment (2nd Edition)
edited by and Frullanti Elisa
submission deadline 30 May 2026 | 1 articles | Viewed by 1305 | Submission Open
Keywords: cancer; lung cancer; new strategies; liquid biopsy; CTC; exosomes; Cf-NA; DdPCR; NGS
(This special issue belongs to the Section Cancer Biomarkers)
Integrating Radiomics and Radiotherapy in Cancer Care: Quantitative Imaging and Efficacy Assessment
edited by
submission deadline 30 May 2026 | 1 articles | Viewed by 929 | Submission Open
Keywords: radiomics; radiogenomics; radiation oncology; imaging biomarkers; predictive models; machine learning; precision radiotherapy; quantitative imaging
(This special issue belongs to the Section Methods and Technologies Development)
Minimally Invasive Surgery and Robotic Techniques in GI Cancer Treatment
edited by Luca Milone and Abid Qureshi
submission deadline 30 May 2026 | 1 articles | Viewed by 917 | Submission Open
Keywords: minimally invasive surgery; robotic surgery; gastrointestinal cancer; surgical oncology; laparoscopic surgery; advanced surgical technology; robotic-assisted procedures; AI in robotic surgery
(This special issue belongs to the Section Methods and Technologies Development)
Revolutionizing Cancer Treatment: Advances in Radiation Therapy
edited by
submission deadline 30 May 2026 | 1 articles | Viewed by 404 | Submission Open
Keywords: radiation therapy; radiooncology; radiobiology; radiosensitivity; high-precision radiotherapy; stereotactic radiotherapy; particle therapy; FLASH radiotherapy; image-guided radiotherapy (IGRT); radiochemotherapy; radioimmunotherapy; translational research; clinical outcome
(This special issue belongs to the Section Cancer Therapy)
Updates on Depression Among Cancer Patients (2nd Edition)
edited by Wen-Yu Hu, and
submission deadline 30 May 2026 | Viewed by 320 | Submission Open
Keywords: depression; psychotherapy; oncology nursing
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Health Services Research in Cancer Care submission deadline 31 May 2026 | 7 articles | Viewed by 20635 | Submission Open
Keywords: cancer care; cancer care outcomes; cancer care services; cancer costs; treatment; health systems; quality; survival; indicators; health technology assessments
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Developments in the Management of Gastrointestinal Malignancies (2nd Edition)
edited by Zachary J. Brown
submission deadline 31 May 2026 | 9 articles | Viewed by 19784 | Submission Open
Keywords: gastrointestinal malignancies; multimodal therapy; chemotherapy; radiotherapy; immunotherapy; localized and metastatic
(This special issue belongs to the Section Cancer Therapy)
Breast Cancer Survivorship: Challenges and Innovations from Treatment to Long-Term Care
edited by Médéa Locquet
submission deadline 31 May 2026 | 12 articles | Viewed by 18469 | Submission Open
Keywords: breast cancer survivorship; cancer treatments; late effects: societal impact; supportive care; psychosocial well-being; cancer treatment optimization; interventions
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Gut Microbiome, Diet and Cancer Risk
edited by
submission deadline 31 May 2026 | 5 articles | Viewed by 13397 | Submission Open
Keywords: gut microbiome; cancer; diet; dysbiosis; immunity; dietary fiber; probiotic; short-chain fatty acids (SCFAs)
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Cancer Biomarkers—Detection and Evaluation of Response to Therapy submission deadline 31 May 2026 | 5 articles | Viewed by 11560 | Submission Open
Keywords: biomarkers; cancer detection; biomarkers of response to antineoplastic drugs; biomarkers of resistance to chemotherapy; biomarkers for targeted therapies
(This special issue belongs to the Section Cancer Biomarkers)
Advances in Treatment of Uveal Melanoma submission deadline 31 May 2026 | 6 articles | Viewed by 11088 | Submission Open
Keywords: uveal melanoma; distant metastases; treatment modalities
(This special issue belongs to the Section Cancer Therapy)
Exploring the Interplay of Glioblastoma Angiogenesis, ROS, and Tumor Microenvironment: Advancements in Combination Therapy and Bioinformatics Approaches
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 10444 | Submission Open
Keywords: glioblastoma; angiogenesis; reactive oxygen species (ROS); hypoxia-inducible factors (HIFs); radiotherapy (RT); bioactive natural compounds; tumor microenvironment (TME); cancer immunotherapy; combination therapy; autophagy; apoptosis; in silico and network pharmacology; bioinformatics
(This special issue belongs to the Section Cancer Metastasis)
Local Management of Breast Cancer: The Evolving Relationship Between Radiotherapy and Surgery
edited by Shengyang Peter Wu
submission deadline 31 May 2026 | 3 articles | Viewed by 9902 | Submission Open
Keywords: biomarker-guided personalized breast treatment; targeted axillary dissection; neoadjuvant therapy; local therapy; radiotherapy reduction; ultrahypofractionated partial breast irradiation
(This special issue belongs to the Section Cancer Therapy)
Advances in Proton Therapy for Head and Neck Cancer: Techniques, Outcomes and Planning Variations
edited by Jun Zhou
submission deadline 31 May 2026 | 3 articles | Viewed by 9672 | Submission Open
Keywords: proton head and neck cancer therapy; protons vs. photons for head and neck cancer treatment; adaptive proton therapy; robustness in proton head and neck cancer therapy; online vs. offline adaptation in proton head and neck cancer therapy
(This special issue belongs to the Section Cancer Therapy)
Updates on Thyroid Cancer
edited by and
submission deadline 31 May 2026 | 4 articles | Viewed by 8544 | Submission Open
Keywords: thyroid cancer; surgery; updates; diagnosis; molecular biology; personalized medicine; artificial intelligence; novel therapeutic strategies; patient outcomes
(This special issue belongs to the Section Cancer Therapy)
MicroRNA in Cancer: From Molecular Mechanisms to Therapeutic Applications
edited by Girish Shukla and
submission deadline 31 May 2026 | 6 articles | Viewed by 7120 | Submission Open
Keywords: microRNA (miRNA) therapeutics; cancer biomarkers; oncogenic and tumor-suppressive miRNAs; miRNA delivery systems; precision oncology
(This special issue belongs to the Section Cancer Biomarkers)
Prostate Cancer and Inflammation
edited by Takuji Hayashi
submission deadline 31 May 2026 | 2 articles | Viewed by 6233 | Submission Open
Keywords: prostate cancer; inflammation; immune cells; cytokine; chemokine; anti-inflammatory agents; diet; microbiome
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Quality of Life in Patients with Brain Tumors
edited by Priya U. Kumthekar, Akanksha Sharma and Margaret Johnson
submission deadline 31 May 2026 | 5 articles | Viewed by 6059 | Submission Open
Keywords: quality of life; palliative care; patient reported outcomes; survivorship; caregiver distress; symptom management
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Advances in Targeted Therapies in Cancer (2nd Edition)
edited by
submission deadline 31 May 2026 | 3 articles | Viewed by 5644 | Submission Open
Keywords: targeted therapy; cancer; antibody therapy; small molecule inhibitor; RNAi therapy; cell-based therapy
(This special issue belongs to the Section Cancer Therapy)
Radiotherapy for the Management of Brain Metastases
edited by Alla Gabriella Wernicke
submission deadline 31 May 2026 | 2 articles | Viewed by 5475 | Submission Open
Keywords: brain metastases; molecular profiles; imaging advancements; systemic treatment options; radiotherapeutic techniques; primary irradiation; re-irradiation; cutting-edge clinical research
(This special issue belongs to the Section Cancer Metastasis)
Molecular Pathways in Cancers (2nd Edition) submission deadline 31 May 2026 | 2 articles | Viewed by 5219 | Submission Open
Keywords: highly prevalent cancers; tumor microenvironment; oncogenesis; progression; novel targeted therapy; prognosis
(This special issue belongs to the Section Molecular Cancer Biology)
The Role of Circulating Tumor Cells in Colorectal Cancer
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 4560 | Submission Open
Keywords: circulating tumor cells (CTC); colorectal cancer (CRC); liquid biopsy; biomarkers; tumor progression; personalized medicine; molecular profiling; metastasis; diagnostic techniques; prognostic evaluation
(This special issue belongs to the Section Cancer Biomarkers)
Focus on Focal Therapy for Prostate Cancer
edited by Abhinav Sidana and Samuel Tremblay
submission deadline 31 May 2026 | 2 articles | Viewed by 4504 | Submission Open
Keywords: focal therapy; prostate cancer treatment; image-guided therapy; oncological outcomes; functional outcome; patient selection; surveillance
(This special issue belongs to the Section Cancer Therapy)
Evolution of Cancer Therapies: Access of Developing Countries to Modern Oncology
edited by
submission deadline 31 May 2026 | 3 articles | Viewed by 4033 | Submission Open
Keywords: conventional cancer therapies; modern oncology; recission medicine; cancer immunotherapy; artificial intelligence; targeted agents; equity and globally equal access
(This special issue belongs to the Section Cancer Therapy)
Therapeutic Optimization of Anti-Tumor Drugs Based on Pharmacokinetics
edited by Paula Fresco and Joaquim António Faria Monteiro
submission deadline 31 May 2026 | 1 articles | Viewed by 3840 | Submission Open
Keywords: anti-cancer drugs; pharmacokinetics; therapeutic drug monitoring; cancer; populational pharmacokinetics models
(This special issue belongs to the Section Cancer Drug Development)
The Future of Cancer Immunotherapy: Biomarkers, Tumor Microenvironment, and Precision Medicine
edited by Aftab Alam
submission deadline 31 May 2026 | 3 articles | Viewed by 3838 | Submission Open
Keywords: immunotherapy; genomics; proteomics checkpoint; CAR T cells; predictive biomarkers; resistance mechanisms; combination approaches; tumor microenvironment
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Survivorship and Quality of Life in Endometrial Cancer
edited by George Koukourakis, , Georgios Angelopoulos and Anthi Miliadou
submission deadline 31 May 2026 | 3 articles | Viewed by 3675 | Submission Open
Keywords: endometrial cancer; quality of life; survivorship
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Current Issues, Innovations, and Emerging Therapies in Thoracic Surgical Oncology
edited by Inderpal S. Sarkaria and Shamus Carr
submission deadline 31 May 2026 | 3 articles | Viewed by 3482 | Submission Open
Keywords: non-small cell lung cancer; esophageal cancer; thymic epithelial tumors; BAP1 malignant mesothelioma; robotic surgery; immunotherapy; cellular therapies; molecular imaging
Advances in Cell and Gene Therapy in Tumors: From Bench to Bedside
edited by Shuhang Wang
submission deadline 31 May 2026 | 1 articles | Viewed by 3291 | Submission Open
Keywords: cell therapy; gene therapy; genetically engineered cells; cancer treatment; clinical trials; pre-clinical study
(This special issue belongs to the Section Cancer Therapy)
Primary Central Nervous System Lymphoma: A Challenging Disease
edited by
submission deadline 31 May 2026 | 2 articles | Viewed by 3104 | Submission Open
Keywords: primary central nervous system lymphoma (PCNSL); diffuse large B cell lymphoma (DLBCL); advanced imaging; novel therapies; prognostic markers
Lymphoid and Myeloid Leukemias—Current Progress in Biology and Treatment
edited by Ewa Robak and
submission deadline 31 May 2026 | 2 articles | Viewed by 3021 | Submission Open
Keywords: acute myeloid leukemia; promyelocytic leukemia; myelomonocytic leukemia; chronic lymphocytic leukemia; hairy cell leukemia; prolymphocytic leukemia; large granular lymphocyte leukemia; acute lymphoblastic leukemia
(This special issue belongs to the Section Molecular Cancer Biology)
Clinical and Translational Research of Urological Cancer submission deadline 31 May 2026 | 2 articles | Viewed by 2886 | Submission Open
Keywords: urological cancer; bladder cancer; surgery; conservative treatment; immunotherapy; radical cystectomy; artifical intelligence
(This special issue belongs to the Section Clinical Research of Cancer)
Decoding the Dynamic Matrix Complexity in Cancer submission deadline 31 May 2026 | 1 articles | Viewed by 2874 | Submission Open
Keywords: extracellular matrix; cancer pathobiology; 3D spheroids/organoids; modeling tumor microenvironment complexity; matrix-based bioscaffolds; matrix remodeling; cell surface matrix mediators and effectors; matrix degrading enzymes; proteoglycans/glycosaminoglycans; collagen; matrix (glyco)proteins; molecular targeting
(This special issue belongs to the Section Tumor Microenvironment)
Current Status and Prospects of Multimodal Treatment for Upper Gastrointestinal Cancer
edited by Koichi Okamoto
submission deadline 31 May 2026 | 3 articles | Viewed by 2476 | Submission Open
Keywords: upper gastrointestinal cancer; esophageal cancer; gastric cancer; esophagogastric junction cancer; chemotherapy; oncology; endoscopic resection; minimally invasive surgery; robotic surgery
(This special issue belongs to the Section Cancer Therapy)
Multimodality Management of Sarcomas (2nd Edition)
edited by
submission deadline 31 May 2026 | 2 articles | Viewed by 2132 | Submission Open
Keywords: sarcomas; multimodal; pathology; radiology; surgery; chemotherapy; radiotherapy
(This special issue belongs to the Section Cancer Therapy)
What’s Behind the Scenes? New Insights in Endometrial Cancer Management and Risk Stratification (2nd Edition)
edited by
submission deadline 31 May 2026 | 2 articles | Viewed by 2094 | Submission Open
Keywords: endometrial cancer; molecular classification; surgical staging; surgery; target therapy; gynecologic oncology; precision medicine; immunohistochemistry
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
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