Combination Therapy in Geriatric Population with Cancer (2nd Edition)
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: 30 December 2025 | Viewed by 125
Special Issue Editor
Interests: geriatric oncology; lung cancer; immunotherapy resistance
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue is the second edition of a previous one, entitled "Combination Therapy in Geriatric Population with Cancer" (https://www.mdpi.com/journal/cancers/special_issues/1DYHD6A28E).
Cancer has a higher chance of developing with age. The increasing life expectancy of the population will, therefore, result in an increasing number of older patients with cancer. Treatment decisions in the older population are often challenging for various reasons. Firstly, the older population is more vulnerable in terms of frailty, organ reserve, comorbidities, polypharmacy, and expectations. Secondly, registration trials predominantly include young and fit patients due to the stringent in- and exclusion criteria, resulting in a lack of data about those outside of these requirements. In addition, the main endpoints of these trials are often survival-related (either overall survival or progression-free survival). Consequently, there is a lack of knowledge on the efficacy, safety, pharmacodynamics, and pharmacokinetics of treatments in older patients. Data on the effect of treatments on daily functioning and quality of life in this older population are, therefore, scarce.
In this Special Issue of Cancers, we welcome original research articles or comprehensive review articles focusing on different treatments (including surgery, radiotherapy, chemotherapy, immunotherapy, targeted therapy, and combinations) for older patients with cancer, regardless of cancer type.
Prof. Dr. Lore Decoster
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- older patients with cancer
- surgery
- radiotherapy
- chemotherapy
- immunotherapy
- targeted therapy
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