Combination Therapy in Geriatric Population with Cancer (2nd Edition)
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: 30 December 2025 | Viewed by 655
Special Issue Editor
Interests: geriatric oncology; lung cancer; immunotherapy resistance
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue is the second edition of a previous one, entitled "Combination Therapy in Geriatric Population with Cancer" (https://www.mdpi.com/journal/cancers/special_issues/1DYHD6A28E).
Cancer has a higher chance of developing with age. The increasing life expectancy of the population will, therefore, result in an increasing number of older patients with cancer. Treatment decisions in the older population are often challenging for various reasons. Firstly, the older population is more vulnerable in terms of frailty, organ reserve, comorbidities, polypharmacy, and expectations. Secondly, registration trials predominantly include young and fit patients due to the stringent in- and exclusion criteria, resulting in a lack of data about those outside of these requirements. In addition, the main endpoints of these trials are often survival-related (either overall survival or progression-free survival). Consequently, there is a lack of knowledge on the efficacy, safety, pharmacodynamics, and pharmacokinetics of treatments in older patients. Data on the effect of treatments on daily functioning and quality of life in this older population are, therefore, scarce.
In this Special Issue of Cancers, we welcome original research articles or comprehensive review articles focusing on different treatments (including surgery, radiotherapy, chemotherapy, immunotherapy, targeted therapy, and combinations) for older patients with cancer, regardless of cancer type.
Prof. Dr. Lore Decoster
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- older patients with cancer
- surgery
- radiotherapy
- chemotherapy
- immunotherapy
- targeted therapy
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