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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Emerging Research on Primary Brain Tumors
edited by Jacob S Young and Mitchel S. Berger
submission deadline 31 Jan 2026 | 6 articles | Viewed by 16898 | Submission Open
Keywords: molecular biomarkers; drug delivery; immunotherapy; personalized medicine; targeted therapies; glioma
(This special issue belongs to the Section Cancer Therapy)
Thyroid Cancer: Diagnosis, Prognosis and Treatment (2nd Edition) submission deadline 31 Jan 2026 | 9 articles | Viewed by 16696 | Submission Open
Keywords: thyroid cancer; ultrasound; molecular imaging; fine-needle aspiration cytology; thyroidectomy; radioactive iodine; radioiodine-refractory thyroid cancer; tyrosine kinase inhibitors
(This special issue belongs to the Section Cancer Therapy)
Empowering Cancer Survivors: A Comprehensive Approach to Supportive Care Through Pharmacological and Non-Pharmacological Approaches Including Exercise, Physical Activity and Nutrition
edited by Kellie Toohey
submission deadline 31 Jan 2026 | 10 articles | Viewed by 14060 | Submission Open
Keywords: cancer; physical activity; exercise; supportive care; holistic care; rehabilitation
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Pathology and Treatment of Triple-Negative Breast Cancer
edited by
submission deadline 31 Jan 2026 | 4 articles | Viewed by 11999 | Submission Open
(This special issue belongs to the Section Cancer Pathophysiology)
Implementation of Physical Activity Promotion in Cancer Care
edited by Sarah Hardcastle
submission deadline 31 Jan 2026 | 4 articles | Viewed by 10393 | Submission Open
Keywords: physical activity; cancer survivors; behaviour change; interventions; cancer care; implementation; health
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
The Tumor Microenvironment: Interplay Between Immune Cells
edited by Jared Rowe and Kristen E. Pauken
submission deadline 31 Jan 2026 | 5 articles | Viewed by 10012 | Submission Open
Keywords: tumor immune microenvironment; metabolic microenvironment; immune cells
(This special issue belongs to the Section Tumor Microenvironment)
Recent Advances and Challenges in Breast Cancer Surgery: 2nd Edition submission deadline 31 Jan 2026 | 6 articles | Viewed by 8581 | Submission Open
Keywords: breast cancer surgery; axillary management; sentinel node oncoplastic surgery; reconstructive surgery; surgical technology; cancer risk reduction surgery; radio-guided surgery
(This special issue belongs to the Section Cancer Therapy)
Recent Advances in Oncology Imaging: 2nd Edition
edited by and
submission deadline 31 Jan 2026 | 4 articles | Viewed by 7791 | Submission Open
Keywords: medical imaging; cancer; oncology; molecular imaging; theragnostics
(This special issue belongs to the Section Methods and Technologies Development)
Biomarkers and Targeted Therapy in Malignant Pleural Mesothelioma
edited by
submission deadline 31 Jan 2026 | 3 articles | Viewed by 6344 | Submission Open
Keywords: malignant mesothelioma; target therapy; biomarkers
(This special issue belongs to the Section Cancer Biomarkers)
Cancer Screening and Primary Care
edited by Marievelisse Soto-Salgado
submission deadline 31 Jan 2026 | 5 articles | Viewed by 5435 | Submission Open
Keywords: screening amenable cancers; screening; primary care; disparities in cancer care; cancer outcomes
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Exploring Skin Cancer: Insights into New Diagnostic, Prognostic, and Therapeutic Strategies
edited by
submission deadline 31 Jan 2026 | 5 articles | Viewed by 5311 | Submission Open
Keywords: melanoma; non-melanoma skin cancer; NMSC; Merkel cell carcinoma; tumor microenvironment; prognosis; treatment
The Role of Apoptosis and Autophagy in Cancer
edited by
submission deadline 31 Jan 2026 | 3 articles | Viewed by 5006 | Submission Open
Keywords: apoptosis; cell death; tumor
(This special issue belongs to the Section Molecular Cancer Biology)
Oral Cancer: The Latest Advances in Clinical and Basic Research (Second Edition)
edited by and Fumihiko Uchida
submission deadline 31 Jan 2026 | 4 articles | Viewed by 4556 | Submission Open
Keywords: oral cancer; clinical research; basic research; surgery; radiotherapy; chemotherapy; molecular biology; immune checkpoint inhibitor
(This special issue belongs to the Section Clinical Research of Cancer)
Prediction of Melanoma
edited by
submission deadline 31 Jan 2026 | 3 articles | Viewed by 4061 | Submission Open
Keywords: melanoma; melanoma genetics; biomarkers; predictive tools; risk prediction; risk factors; artificial intelligence
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Clinical Studies and Outcomes in Urologic Cancer
edited by Nikolaos Pyrgidis
submission deadline 31 Jan 2026 | 3 articles | Viewed by 3964 | Submission Open
Keywords: urologic cancer; clinical outcomes; prostate cancer; urothelial cancer; kidney cancer; survival analysis; treatment response; quality of life; novel therapies; oncology
(This special issue belongs to the Section Clinical Research of Cancer)
Minimally Invasive Approaches in Urological Oncology: Current Trends and Innovations submission deadline 31 Jan 2026 | 3 articles | Viewed by 2920 | Submission Open
Keywords: minimally invasive; robotic; laparoscopic; uro-oncology; prostate cancer; bladder cancer; kidney cancer; testicular cancers; quality of life; penile cancer
(This special issue belongs to the Section Clinical Research of Cancer)
Recent Advances in Nanomedicine-Based Cancer Immunotherapy
edited by Navin Kumar Verma, and
submission deadline 31 Jan 2026 | 1 articles | Viewed by 2886 | Submission Open
Keywords: cancer nano-therapy; nano-enabled therapeutic; immune checkpoint inhibitors; tumor immunosuppression; adoptive cell therapy; CAR T-cell therapy; tumor-infiltrating lymphocyte therapy; monoclonal antibody therapy for cancer; cancer vaccines; immune system modulators
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Post-Neoadjuvant Strategies in Breast Cancer (2nd Edition)
edited by , Tanja Fehm and
submission deadline 31 Jan 2026 | 1 articles | Viewed by 2844 | Submission Open
Keywords: chemotherapy; prospective trials; clinical investigation; breast tumor; local recurrence; overall survival
(This special issue belongs to the Section Cancer Therapy)
Computational Research in Cancer Neuroscience
edited by Shaolei Teng
submission deadline 31 Jan 2026 | 1 articles | Viewed by 2762 | Submission Open
Keywords: machine learning; large language models; protein structure modeling; omics data analysis; neural– cancer communication; tumor microenvironments; personalized medicine; targeted therapies; cancer neuroscience
(This special issue belongs to the Section Methods and Technologies Development)
Novel Perspectives in Hepato-Biliary and Pancreatic Cancer
edited by Tudor Mocan and Emil-Ioan Moiș
submission deadline 31 Jan 2026 | 2 articles | Viewed by 2338 | Submission Open
Keywords: HCC; cholangiocarcinoma; surgery; biliary drainage; pancreatic cancer; combination therapies
(This special issue belongs to the Section Cancer Therapy)
Advances and Future Developments in Liver Transplantation for Cancers: 2nd Edition
edited by
submission deadline 31 Jan 2026 | 2 articles | Viewed by 2302 | Submission Open
Keywords: machine perfusion; marginal graft; split liver; immunotherapy; auxiliary liver transplantation; digital twin; modeling; organoid
(This special issue belongs to the Section Transplant Oncology)
Cancers Hijack Immune Surveillance and Tumor Microenvironment Leading to Immune Evasion
edited by , Viktor Umansky and
submission deadline 31 Jan 2026 | 1 articles | Viewed by 2107 | Submission Open
Keywords: anti-tumor immunity; cancer immunotherapy; immune evasion; immune response modulation; immunosuppression; immune surveillance; manipulating IR components function and migration; metabolic modulation of the TME; metabolic reprogramming; tumor-associated immune cells; tumor microenvironment (TME)
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Clinical Trials and Outcomes for Non-Small Cell Lung Cancer submission deadline 31 Jan 2026 | 2 articles | Viewed by 1957 | Submission Open
Keywords: non-small cell lung cancer; oncogenic alterations; clinical trial; systemic therapy; targeted therapy; immunotherapy; radiotherapy; real-world data; surgery; drug development
(This special issue belongs to the Section Clinical Research of Cancer)
Head and Neck Cancer: Survivorship Challenges and Therapeutic Approaches
edited by , Avraham Eisbruch and
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1883 | Submission Open
Keywords: head and neck cancer; supportive care; survivorship care; physiotherapy; quality of life; lifestyle interventions
(This special issue belongs to the Section Cancer Therapy)
Radiosensitivity and Radiotoxicity in Cancer submission deadline 31 Jan 2026 | 1 articles | Viewed by 1640 | Submission Open
Keywords: radiation therapy; clinical outcome; radiosensitivity; radiotoxicity; biomarkers; bioinformatics; systems biology
(This special issue belongs to the Section Methods and Technologies Development)
Advanced Strategies in the Care of Hepatocellular Carcinoma Patients (2nd Edition) submission deadline 31 Jan 2026 | 1 articles | Viewed by 1426 | Submission Open
Keywords: hepatocellular carcinoma; hepatic resection; hepatectomy; liver resection; liver surgery; parenchymal-sparing liver surgery; intraoperative ultrasound; liver-specific magnetic resonance imaging; trans-arterial therapy; liver function; FibroScan
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Advanced Glycation End-Products and Its Receptors in Cancer Progression
edited by Bhaumik B. Patel
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1404 | Submission Open
Keywords: advanced glycation end products; toxic advanced glycation end products; receptor for advanced glycation end products (RAGEs); glycosaminoglycans; cancer; cancer stem cells (CSCs); tumor immune microenvironment (TME)
(This special issue belongs to the Section Tumor Microenvironment)
Nutrition in Survivors with Advanced Cancer: The Role of Appetite, Muscle Wasting, Obesity, and Altered Body Composition
edited by Egidio Del Fabbro
submission deadline 31 Jan 2026 | 1 articles | Viewed by 939 | Submission Open
Keywords: advanced cancer; nutrition; wasting; body composition; multimodal
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Emerging Technologies in Thoracic Surgery
edited by Filippo Lococo and
submission deadline 31 Jan 2026 | 1 articles | Viewed by 898 | Submission Open
Keywords: lung cancer; molecular biology; liquid biopsy; immunotherapy; precision surgery; minimally invasive surgery; new technologies; artificial intelligence
(This special issue belongs to the Section Methods and Technologies Development)
Novel Approaches in the Management of Gynecological Cancers submission deadline 31 Jan 2026 | 1 articles | Viewed by 801 | Submission Open
Keywords: gynecological cancer; ovarian cancer; endometrial cancer; cervical cancer; vulvar cancer; surgical management; clinical management
(This special issue belongs to the Section Cancer Therapy)
Updates on Imaging of Common Urogenital Neoplasms 2nd Edition
edited by Athina C Tsili
submission deadline 31 Jan 2026 | 1 articles | Viewed by 747 | Submission Open
Keywords: urogenital neoplasms; renal cell carcinoma; prostatic neoplasms; urinary bladder neoplasms; testicular neoplasms; uterine neoplasms; ovarian neoplasms; ultrasonography; computed tomography; magnetic resonance imaging
(This special issue belongs to the Section Methods and Technologies Development)
New Insights in Nanomedicine and Targeted Drugs for Breast Cancer
edited by , Gennaro Sanità, Alessandro Venuta and Rosarita Nasso
submission deadline 31 Jan 2026 | Viewed by 440 | Submission Open
Keywords: breast cancer; nanoparticles; active targeting; BC; nanomedicine
(This special issue belongs to the Section Cancer Drug Development)
The Biology of Hepatocellular Carcinoma: Implications for Genomic and Immune Therapies (2nd Edition)
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 416 | Submission Open
Keywords: hepatocellular carcinoma; diagnosis; treatment; molecular targeted agent; immune checkpoint inhibitor; artificial intelligence
(This special issue belongs to the Section Molecular Cancer Biology)
The Cancer Stem Cells and the Quiescence
edited by
submission deadline 31 Jan 2026 | Viewed by 398 | Submission Open
Keywords: cancer stem cells; new markers; organoid cultures; cancer cell dormancy and quiescence; metastasis; animal models; metabolism; drug resistance
(This special issue belongs to the Section Molecular Cancer Biology)
Lymph Node Involvement in Cervical Cancer: From Single Isolated Tumor Cell to Macrometastasis
edited by , and Thomas Gaillard
submission deadline 31 Jan 2026 | Viewed by 347 | Submission Open
Keywords: cervical cancer; lymph nodes; metastasis; isolated Tumor Cells; sentinel lymph node; non-sentinel lymph node; tumor-draining lymph nodes; microenvironment; one-step nucleic acid amplification; imaging
(This special issue belongs to the Section Tumor Microenvironment)
Recent Advances in Pancreatic Surgery for Pancreatic Ductal Adenocarcinoma (2nd Edition)
edited by Shuji Isaji
submission deadline 31 Jan 2026 | Viewed by 254 | Submission Open
Keywords: neoadjuvant therapy; adjuvant therapy; resectability; conversion surgery; surgical technique; laparoscopic surgery; robotic surgery
(This special issue belongs to the Section Cancer Therapy)
Surgery for Lung Cancer: Robot-Assisted Versus Video-Assisted Thoracoscopic Surgery and Open Thoracotomy
edited by
submission deadline 31 Jan 2026 | Viewed by 224 | Submission Open
Keywords: laparoscopic thoracic surgery; open thoracotomy; robotic thoracic surgery (RTS); lung cancer; surgical treatment; minimally invasive intervention
(This special issue belongs to the Section Cancer Therapy)
Recent Advances in the Molecular Biology of Urologic Cancers: Integrative Insights from Pathogenesis to Clinical Applications
edited by
submission deadline 31 Jan 2026 | Viewed by 202 | Submission Open
Keywords: urologic cancers; molecular biology; pathogenesis; precision medicine; biomarkers; multi-omics; targeted therapies; immunotherapy; translational research; clinical applications
(This special issue belongs to the Section Molecular Cancer Biology)
Prostate-Specific Membrane Antigen (PSMA)-Targeted Radionuclide Therapy in Cancer
edited by and
submission deadline 31 Jan 2026 | Viewed by 193 | Submission Open
Keywords: PSMA-TRNT; radioligand therapy; radionuclide therapy; theranostics; prostate-specific membrane antigen (PSMA); PSMA targeted; PSMA ligands; prostate cancer (PCa); metastatic castration-resistant prostate cancer (mCRPC)
(This special issue belongs to the Section Methods and Technologies Development)
Diagnosis and Biomarkers for Hematologic Malignancies submission deadline 31 Jan 2026 | Viewed by 180 | Submission Open
Keywords: hematologic malignancies; diagnosis; biomarkers
(This special issue belongs to the Section Cancer Biomarkers)
Breast Cancer and Stem Cells
edited by Leandro Marcelo Martinez
submission deadline 31 Jan 2026 | Viewed by 164 | Submission Open
Keywords: breast cancer; cancer stem cells; tumor microenvironment; metastasis; therapeutic strategies; in vitro models
(This special issue belongs to the Section Molecular Cancer Biology)
Curative Therapies for Non-Small and Small Cell Lung Cancers
edited by John Michael Varlotto
submission deadline 31 Jan 2026 | Viewed by 142 | Submission Open
Keywords: radiotherapy; surgery; early stage NSCLC; oligometastases; immunotherapy; small-cell lung cancer
(This special issue belongs to the Section Cancer Therapy)
Transformative Drug Innovations Reshaping Myeloma Treatment
edited by Despina Fotiou
submission deadline 31 Jan 2026 | Viewed by 136 | Submission Open
Keywords: multiple myeloma; cellular therapy; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
Laryngeal Cancer: Diagnostic Workup, Treatment, and Complications
edited by Francesco Mattioli, and Edoardo Serafini
submission deadline 31 Jan 2026 | Viewed by 134 | Submission Open
Keywords: laryngeal cancers; diagnosis; laryngeal surgery; transoral laser microsurgery; transoral robotic surgery
(This special issue belongs to the Section Clinical Research of Cancer)
Neoadjuvant Therapy for Urologic Cancer
edited by Marlon Perera and David Chen
submission deadline 31 Jan 2026 | Viewed by 124 | Submission Open
Keywords: urologic oncology; neoadjuvant therapy; treatment; improved survival
(This special issue belongs to the Section Cancer Therapy)
Conversion Surgery for Initially Unresectable, Locally Advanced, Metastatic or Recurrent Gastrointestinal Cancers
edited by
submission deadline 31 Jan 2026 | Viewed by 122 | Submission Open
Keywords: conversion surgery; locally advanced disease; metastatic disease; chemotherapy; radiotherapy; immunotherapy; heptobiliary-pancreatic cancers; gastrointestinal tract cancers
(This special issue belongs to the Section Clinical Research of Cancer)
Immune Profiling in Gastrointestinal Cancers: Implications for Precision Immunotherapy
edited by
submission deadline 31 Jan 2026 | Viewed by 120 | Submission Open
Keywords: gastrointestinal cancer; immune profiling; immunocompetent cells; personalized immunotherapy; biomarkers; precision medicine; tumor microenvironment; tumor-infiltrating lymphocytes; immune checkpoint inhibitors; microbiota– immunity interactions; single-cell analysis; spatial transcriptomics
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Personalized Cancer Therapy: Strategies for Overcoming On-Target and Bypass Resistance
edited by
submission deadline 31 Jan 2026 | Viewed by 91 | Submission Open
Keywords: resistance mechanisms; biomarker; oncogene dependency; target therapy; personalized therapy
(This special issue belongs to the Section Molecular Cancer Biology)
Advances in Thoracic Oncology Research
edited by
submission deadline 1 Feb 2026 | 1 articles | Viewed by 2884 | Submission Open
Keywords: lung cancer; mediastinal; thymic; neuroendocrine; robotic; VATS; chest wall; chemotherapy; immunotherapy; radiotherapy
(This special issue belongs to the Section Cancer Therapy)
Therapy for HER2 Breast Cancer
edited by and Sandra M. Swain
submission deadline 1 Feb 2026 | Viewed by 136 | Submission Open
Keywords: antibody– drug conjugate; trastuzumab; pertuzumab; tyrosine kinase inhibitor; trastuzumab deruxtecan
(This special issue belongs to the Section Cancer Therapy)
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