Exploring Skin Cancer: Insights into New Diagnostic, Prognostic, and Therapeutic Strategies

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Tumor Microenvironment".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 71

Special Issue Editor

1. Oncologic Dermatology Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna, Bologna, Italy
2. Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum of Bologna, Bologna, Italy
Interests: melanoma; NMSC; skin cancer; medical oncology; clinical trials; surgery; medical treatment
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Special Issue Information

Dear Colleagues,

Skin cancer is among the most prevalent malignancies worldwide, representing one-third of all cancer diagnoses. It encompasses a diverse spectrum of tumors, each presenting unique prognostic and therapeutic challenges. While cutaneous melanoma is well known for its aggressive nature and metastatic potential, squamous cell carcinoma and basal cell carcinoma account for nearly 90% of skin cancers, imposing a significant global healthcare burden. Moreover, rare but highly aggressive tumors, such as Merkel cell carcinoma, pose further diagnostic, prognostic, and therapeutic complexities. Recent breakthroughs in non-invasive and AI-powered imaging, as well as biomarker-based screening, have transformed skin cancer detection. At the same time, innovative therapeutic approaches—such as immune checkpoint inhibitors, targeted therapies, and nanotechnology-driven drug delivery systems—have reshaped treatment paradigms and enhanced precision medicine in skin cancer care. This Special Issue explores the latest innovations in skin cancer diagnosis, prognosis, and treatment, focusing on their clinical significance and future role in personalized medicine. By integrating emerging technologies with established approaches and current evidence, clinicians and researchers may optimize both diagnostic and therapeutic strategies, thereby improving patient outcomes.

Dr. Emi Dika
Guest Editor

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Keywords

  • melanoma
  • non-melanoma skin cancer
  • NMSC
  • Merkel cell carcinoma
  • tumor microenvironment
  • prognosis
  • treatment

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Published Papers

This special issue is now open for submission.
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