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Cancers
Special Issues
Recent Advances and Challenges in Breast Cancer Surgery: 2nd Edition
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Recent Advances and Challenges in Breast Cancer Surgery: 2nd Edition

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".

Deadline for manuscript submissions: 31 May 2025 | Viewed by 1025

Special Issue Editor

Dr. Antonio Piñero-Madrona

E-Mail Website
Guest Editor
Breast Unit Surgery, Department of General Surgery, University Hospital "Virgen de la Arrixaca", BioMedical Research Institute of Murcia (IMIB-Arrixaca), University of Murcia, E-30120 Murcia, Spain
Interests: surgical oncology; breast cancer; melanoma; sentinel node; lymph oncology; metastases; wound healing
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

During the last fifty years, we have witnessed a revolution in the field of breast cancer management. Therapeutic de-escalation, which has been seen in all areas of treatment, is especially visible in the case of surgical treatment, which has moved to precision treatments based on patient and tumor characteristics.

It has been replaced by less invasive procedures, and technical and technological advances change the way of facing surgical treatment of the breast and axilla.

This Special Issue of Cancers aims to review and update the surgical treatment of breast cancer through several articles focused on different aspects of the surgical technique and its relationship with technological advances and the relationship of surgery with other therapeutic and diagnostic modalities.

Dr. Antonio Piñero-Madrona
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • breast cancer surgery
  • axillary management
  • sentinel node oncoplastic surgery
  • reconstructive surgery
  • surgical technology
  • cancer risk reduction surgery
  • radio-guided surgery

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Published Papers (2 papers)

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Research

11 pages, 226 KiB  
Article
Total Sealing Technique: A Preliminary Study on a Novel Surgical Approach That Significantly Reduces the Incidence of Upper Extremity Lymphedema Following Axillary Dissection in Patients with Breast Cancer
by Naoya Ikeda, Takuya Nagata, Teiji Umemura and Manabu Watanabe
Cancers 2025, 17(8), 1285; https://doi.org/10.3390/cancers17081285 - 10 Apr 2025
Viewed by 267
Abstract
The primary goal in treating patients with breast cancer who have positive axillary lymph nodes is to achieve optimal tumor control while minimizing side effects that include breast cancer-related lymphedema (BCRL) [...] Full article
(This article belongs to the Special Issue Recent Advances and Challenges in Breast Cancer Surgery: 2nd Edition)
11 pages, 257 KiB  
Article
Optimizing Outcomes in Breast Reconstruction: The Role of Hormonal Therapy Management
by Eduardo Saorín-Gascón, Óscar Nova-Tayant, Ramón A. Moreno-Villalba, Juan de Dios García-Contreras, Clemente José Fernández-Pascual, Asunción M. Mora-Ortíz, Maria del Carmen Servet-Pérez de Lema, Alba Quiles-Hevia and Antonio Piñero-Madrona
Cancers 2025, 17(4), 672; https://doi.org/10.3390/cancers17040672 - 17 Feb 2025
Viewed by 490
Abstract
Background: Breast cancer comprises diverse subtypes with prognostic and therapeutic implications. Hormone therapy plays a crucial role in managing tumors expressing hormonal receptors, but its impact on breast reconstruction outcomes remains unclear. This study aims to evaluate the association between perioperative hormone therapy [...] Read more.
Background: Breast cancer comprises diverse subtypes with prognostic and therapeutic implications. Hormone therapy plays a crucial role in managing tumors expressing hormonal receptors, but its impact on breast reconstruction outcomes remains unclear. This study aims to evaluate the association between perioperative hormone therapy continuation and the incidence of postoperative complications following breast reconstruction (including autologous, prosthetic, and hybrid techniques), with a focus on identifying specific complication types to refine patient management strategies. Methods: A retrospective analysis was conducted on patients who underwent breast reconstruction following mastectomy for hormone receptor-positive breast cancer. Patients were categorized based on the appropriate discontinuation of hormonal therapy. Clinical data, including patient characteristics, treatment regimens, and complication occurrences, were registered and analyzed. Results: Inadequate suspension of hormonal therapy during the perioperative period was significantly associated with a higher rate of complications, particularly in the immediate and early phases. Complications such as skin alterations, flap failure, seroma development, and clinical infection showed significant associations with the continuation of hormone therapy (p < 0.05). No significant differences were observed for other complications. Conclusions: Preliminary findings suggest a potential correlation between the continuation of hormone therapy during the perioperative phase and the development of complications following breast reconstruction. Full article
(This article belongs to the Special Issue Recent Advances and Challenges in Breast Cancer Surgery: 2nd Edition)
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