Post-Neoadjuvant Strategies in Breast Cancer (2nd Edition)
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 42
Special Issue Editors
Interests: cancer research; mediator response; chemotherapy; radiation therapy
Special Issues, Collections and Topics in MDPI journals
Interests: minimal residual disease in breast and gynecologic cancers; CTC-based therapeutic strategies
Special Issues, Collections and Topics in MDPI journals
Interests: breast cancer; radiotherapy; deep inspiration breath hold
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The post-neoadjuvant setting in early breast cancer is an attractive scenario for improving patient outcome by stratifying the adjuvant treatment according to the pathological response to the neoadjuvant systemic treatment. This strategy allows for studying new systemic therapies or new combinations of treatment modalities in high-risk patients who did not achieve pathologic complete response after primary treatment.
In this context, the findings after neoadjuvant therapy can be used as an in vivo sensitivity test, and further tailored treatment can improve the outcome in high-risk patients. Moreover, tailored de-escalation strategies of locoregional treatments could be another step towards reducing morbidity in patients with good response rates. To date, there is no clear evidence and there is no standard therapy routinely proposed for patients with residual disease after neoadjuvant chemotherapy, and few trials have addressed this setting. Therefore, the treatment of patients in the post-neoadjuvant setting remains a clinical challenge, with only a limited amount of data supporting the use of additional adjuvant chemotherapy.
The present Special Issue of Cancers focuses on recent advances and future perspectives in the various aspects of post-neoadjuvant strategies in breast cancer patients.
Prof. Dr. Edwin Bölke
Prof. Dr. Tanja Fehm
Dr. Stefanie Corradini
Guest Editors
Manuscript Submission Information
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Keywords
- chemotherapy
- prospective trials
- clinical investigation
- breast tumor
- local recurrence
- overall survival
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