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Cancers
Special Issues
Minimally Invasive Approaches in Urological Oncology: Current Trends and Innovations
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Minimally Invasive Approaches in Urological Oncology: Current Trends and Innovations

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Clinical Research of Cancer".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 125

Special Issue Editors

Prof. Dr. Alchiede Simonato

E-Mail Website
Guest Editor
Department of Surgical, Oncological, and Oral Sciences, University of Palermo, 90127 Palermo, Italy
Interests: urology; oncologic surgery; robotic surgery; laparoscopy; prostate; bladder; kidney; penis; testis
Special Issues, Collections and Topics in MDPI journals
Dr. Nicola Pavan

E-Mail Website
Guest Editor
Department of Surgical, Oncological, and Oral Sciences, University of Palermo, 90127 Palermo, Italy
Interests: prostate cancer; bladder cancer; kidney cancer; robotic surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Minimally invasive surgery (MIS) has emerged as a transformative approach in the treatment of urological cancers. This Special Issue delves into the innovative techniques and outcomes associated with MIS in urological oncology. MIS, including laparoscopy and robotic-assisted procedures, offers numerous advantages, such as reduced blood loss, shorter hospital stays, and faster recovery times compared to traditional open surgeries. The articles in this Special Issue explore the application of MIS in the management of various urological cancers, including prostate, kidney, bladder, and testicular cancers. Additionally, they investigate the long-term oncological outcomes, patient quality of life, and cost-effectiveness of MIS. By showcasing the latest research and clinical experiences, this Special Issue aims to advance our understanding of the role of MIS in improving patient outcomes and reshaping the landscape of urological cancer treatment.

Prof. Dr. Alchiede Simonato
Dr. Nicola Pavan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • minimally invasive
  • robotic
  • laparoscopic
  • uro-oncology
  • prostate cancer
  • bladder cancer
  • kidney cancer
  • testicular cancers
  • quality of life
  • penile cancer

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Published Papers (1 paper)

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10 pages, 459 KiB  
Article
A Closer Look at Radiation Exposure During Percutaneous Cryoablation for T1 Renal Tumors
by Luna van den Brink, Michaël M. E. L. Henderickx, Otto M. van Delden, Harrie P. Beerlage, Daniel Martijn de Bruin and Patricia J. Zondervan
Cancers 2025, 17(12), 2016; https://doi.org/10.3390/cancers17122016 - 17 Jun 2025
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Abstract
Introduction: Percutaneous cryoablation (PCA) can be a valid alternative to partial nephrectomy for patients with cT1a renal tumors. A potential disadvantage of PCA is radiation exposure for patients, though the exact significance of this is unknown. This study aims to uncover the degree [...] Read more.
Introduction: Percutaneous cryoablation (PCA) can be a valid alternative to partial nephrectomy for patients with cT1a renal tumors. A potential disadvantage of PCA is radiation exposure for patients, though the exact significance of this is unknown. This study aims to uncover the degree of radiation exposure during PCA and what factors are of influence. Methods: This is a retrospective analysis of a prospectively maintained database of patients who underwent CT-guided PCA for cT1 renal cell carcinoma (RCC) between January 2014 and September 2024. The median effective dose (mSV) of PCA was calculated and compared to the expected cumulative radiation exposure during follow-up. Multivariate linear regression was performed to identify factors predictive of higher radiation exposure (mSV). Results: A total of 164 PCAs were performed, with radiation data available for 133 cases. Mean age was 65 (±11) years and the mean tumor diameter was 28 (±9.6) mm. Median effective dose of the CA procedures was 26 mSV (IQR 18–37). The estimated cumulative effective dose of follow-up CT scans according to 2016 and 2024 European Association of Urology guidelines was 158 (IQR 117–213) and 105 mSV (IQR 78–142), respectively. Multivariate linear regression analysis identified BMI (OR 1.723, p < 0.001), the number of needles used (OR 4.060, p < 0.001), and the necessity for additional procedures (OR 8.056, p < 0.001) as significant predictors of a higher effective dose. Conclusions: We found a median effective dose of 26 mSV for PCA, which is relatively low compared to the cumulative radiation exposure associated with CT scans during follow-up of patients post-ablation according to the guidelines. Furthermore, increased BMI, a higher number of required needles and the execution of additional procedures are all associated with a higher effective dose. Full article
(This article belongs to the Special Issue Minimally Invasive Approaches in Urological Oncology: Current Trends and Innovations)
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