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Biosensors publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Micro-nano Optic-Based Biosensing Technology and Strategy

edited by

Wenchao Zhou

submission deadline 20 May 2025 | 10 articles | Viewed by 15882 | Submission Open

Keywords: micro/nano-optics biosensor; microfluidic; lab-on-a-chip; point-of-care test; SPR; optical micro/nano fiber; metasurface; nanophotonics

(This special issue belongs to the Section Optical and Photonic Biosensors)

Biosensing Strategies for Food Safety Applications

edited by

Hongmei Cao

submission deadline 20 May 2025 | 3 articles | Viewed by 5160 | Submission Open

Keywords: biosensors; food safety; pathogen; antibody; immunosensor; nanozyme; electrochemiluminescence

(This special issue belongs to the Section Environmental Biosensors and Biosensing)

Nanophotonics and Surface Waves in Biosensing Applications

edited by

Yuanjiang Xiang

and

Leyong Jiang

submission deadline 25 May 2025 | Viewed by 237 | Submission Open

Keywords: photonic crystal biosensors; metasurface-based sensors; surface plasmon resonance-based sensors; optical Tamm state-based sensors; topological edge state-based sensors; modes coupling-based sensors; surface wave-based sensors

(This special issue belongs to the Section Optical and Photonic Biosensors)

Nanoparticle-Based Biosensors for Detection

edited by

Hyeon-Yeol Cho

submission deadline 30 May 2025 | 5 articles | Viewed by 10353 | Submission Open

Keywords: functional nanoparticle; gold nanoparticle; magnetic nanoparticle; quantum dots; silica nanoparticle; biosensor; chemical sensors; immunosensors; electrochemical biosensors

(This special issue belongs to the Section Biosensors and Healthcare)

Microfluidics and MEMS for Diagnostics and Biomedical Applications—2nd Edition

edited by Xiaoyan Liu

submission deadline 30 May 2025 | Viewed by 204 | Submission Open

Keywords: microfluidics; microfabrication; microelectromechanical systems; diagnostics; biosensors; micromachining; integration; implantable; wearable

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Advanced Nanomaterials for Electrochemical Biosensing Application

edited by

Sungbo Cho

submission deadline 31 May 2025 | 4 articles | Viewed by 11733 | Submission Open

Keywords: advanced nanostructured materials; foods; drug delivery; environment; disease; biosensing; DNA nanotechnology; real-time monitoring; smart electrochemical devices; miniaturized devices; paper-based electrochemical sensors

(This special issue belongs to the Section Biosensor Materials)

Probes for Biosensing and Bioimaging

edited by

Hongwen Liu

and

Zhiqiang Mao

submission deadline 31 May 2025 | 5 articles | Viewed by 11060 | Submission Open

Keywords: fluorescent probe; small-molecular probe; biosensing; bioimaging

(This special issue belongs to the Section Optical and Photonic Biosensors)

Innovative Biosensing Technologies for Sustainable Healthcare

edited by Hua Li and Shoujing Zheng

submission deadline 31 May 2025 | 6 articles | Viewed by 8376 | Submission Open

Keywords: sustainability; healthcare; biosensor; bioactuator; biorobot; rehabilitation; smart biomaterials; healthcare device/system; green biomaterials; smart biotechnology

(This special issue belongs to the Section Biosensor Materials)

Advanced Fluorescence Biosensors

edited by Simone Berneschi and

Cosimo Trono

submission deadline 31 May 2025 | 6 articles | Viewed by 7051 | Submission Open

Keywords: fluorescence; biosensors; label-based biosensors; förster resonance energy transfer (FRET); metal-enhanced fluorescence (MEF); total internal reflection fluorescence (TIRF); nanomaterials; upconversion; optical microcavities; optical fibers

(This special issue belongs to the Section Optical and Photonic Biosensors)

Microfluidics for Biomedical Applications (3rd Edition)

edited by

Nan Xiang

submission deadline 31 May 2025 | 7 articles | Viewed by 6680 | Submission Open

Keywords: microfluidics; cell manipulation and detection; point-of-care testing; lab on a chip; biomedical applications

(This special issue belongs to the Section Biosensors and Healthcare)

Single-Molecule Biosensing: Recent Advances and Future Challenges

edited by

Chunyang Zhang

submission deadline 31 May 2025 | 3 articles | Viewed by 6219 | Submission Open

Keywords: single-molecule detection; biosensor; diagnosis; biomarker

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Prof. Shishmon Belkin 30th Anniversary of Working in Bioluminescent Bioreporter Bacteria Biosensors

edited by

Robert Steven Marks

, Kun Jia,

Evgeni Eltzov

and Boris Polyak

submission deadline 31 May 2025 | 3 articles | Viewed by 5104 | Submission Open

Keywords: bioluminescence; bioreporters; biosensors; applications; commercialization

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Wearable and Implantable Bioelectronics for Advanced Biosensing and Human Health Monitoring

edited by Faheem Ershad, Farnaz Lorestani and

Binghao Wang

submission deadline 31 May 2025 | 3 articles | Viewed by 4137 | Submission Open

Keywords: wearable biosensors; bioelectronics; stretchable electronics; multimodal biosensing; biomarker detection

(This special issue belongs to the Section Wearable Biosensors)

Advances in Biosensing and Bioanalysis Based on Nanozymes

edited by Lei Jiao and Ruijin Zeng

submission deadline 31 May 2025 | 2 articles | Viewed by 3118 | Submission Open

Keywords: nanozymes; biosensors; small molecules; biomarkers; metal ions; catalytic mechanism; activity regulation

(This special issue belongs to the Section Biosensors and Healthcare)

Optical Biosensors for Label-Free Detection

edited by

Miquel Avella-Oliver

and

Ángel Maquieira

submission deadline 31 May 2025 | 1 articles | Viewed by 2286 | Submission Open

Keywords: label-free; biosensor; plasmonics; photonics; nanostructure; transduction; point-of-care; lab-on-a-chip; wearable; SPR; SERS; waveguiding; interferometry; immunosensor; DNA biosensors

(This special issue belongs to the Section Optical and Photonic Biosensors)

Microfluidic Biosensors for Point-of-Care Nucleic Acid Amplification Tests (2nd Edition)

edited by

Kieu The Loan Trinh

submission deadline 31 May 2025 | 1 articles | Viewed by 2223 | Submission Open

Keywords: microfluidics; biosensors; point-of-care; nucleic acid amplification tests; paper-based microfluidics; lab-on-a-chip; fabrication; sample preparation; isothermal amplification; on-chip detection

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Micro-/Nano Biomedical Point-of-Care Devices

edited by

Danny van Noort

submission deadline 31 May 2025 | 2 articles | Viewed by 1960 | Submission Open

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Recent Advancements in Novel Carbon Nanomaterials in Bioelectronics and Biosensors

edited by

Pranati Nayak

and

George Knopf

submission deadline 31 May 2025 | Viewed by 399 | Submission Open

Keywords: carbon-based nanomaterials; biosensors; bioelectronics; surface engineering; environmental remediation; health care monitoring

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Nucleic Acid Aptamer-Based Bioassays

edited by

Jee-Woong Park

and

Su Jin Lee

submission deadline 31 May 2025 | Viewed by 254 | Submission Open

Keywords: SELEX; aptamer biosensor; aptasensor; electrochemical aptamer sensor; aptamer truncation; prediction of aptamer

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Advanced Sensing Technologies in Drug Delivery: Progress, Challenges, and Future Perspectives

edited by

Xiaojun Xian

submission deadline 31 May 2025 | Viewed by 204 | Submission Open

Keywords: drug delivery systems; wearable drug delivery; closed-loop drug delivery; transdermal drug delivery; sensor-based drug delivery; responsive drug delivery; point-of-care drug delivery; electrochemical sensors; implantable sensors; electronic skin; real-time monitoring; controlled drug release; microfluidics; personalized medicine; sensor technologies in healthcare

(This special issue belongs to the Section Biosensors and Healthcare)

New Advances in Bioimaging-Guided Anticancer and Antibacterial Therapy

edited by Yuxin Liu

submission deadline 31 May 2025 | Viewed by 164 | Submission Open

Keywords: biosensor; probe; fluorescence imaging; MRI; CT; PET; drug delivery; therapy; anticancer; antibacterial

(This special issue belongs to the Section Optical and Photonic Biosensors)

Fluorescent Probes for Bioimaging and Biosensors

edited by Yan Zhao,

Weiheng Kong

and Shengyan Yin

submission deadline 1 Jun 2025 | Viewed by 147 | Submission Open

Keywords: bioimaging; fluorescent probes; biosensors; near-infrared two-region fluorescence; molecular diagnostics

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Advances in Label-Free Biosensing with Field-Effect Transistor Technology: Materials, Design Strategies, Approaches, and Applications

edited by

Khalil Tamersit

and

Harm Van Zalinge

submission deadline 1 Jun 2025 | Viewed by 140 | Submission Open

Keywords: ion-sensitive field-effect transistors (ISFETs) for biosensing; radiation-sensitive field-effect transistors (RADFET) in medical dosimetry; advancements in modeling and simulation of FET-based biosensors; label-free biosensing using ultrascaled devices; CMOS-compatible biosensor technology; BioFETs based on carbon nanomaterials (graphene; CNT; GNR; etc.); 2D transistor-based nanobiosensors; smart biosensing systems using FET technology; bio-integrated field-effect transistor biosensors; artificial intelligence applications in FET-based biosensors; flexible field-effect transistor biosensing devices; fabrication techniques for FET-based biosensors; experimental methodologies in biosensor development; transistor in biosensing and medical sensing

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Polymers-Based Biosensors and Bioelectronics: Designs and Applications

edited by

Vinh Van Tran

submission deadline 20 Jun 2025 | 4 articles | Viewed by 6742 | Submission Open

Keywords: polymers-based biosensor; gas sensor; transistor-based biosensor; organic field-effect transistors (OFETs); conductive polymers; organic electronics; smart materials (self-healable materials; hydrogels)

(This special issue belongs to the Section Biosensor Materials)

Biochips for Biosensing of Microphysiological Events

edited by

Sung-Min Kang

and

Seungjin Lee

submission deadline 25 Jun 2025 | Viewed by 1989 | Submission Open

Keywords: organ-on-a-chip; microfluidics; cell culture; biosensing; microphysiological environment

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Fluorescent Materials with Excellent Biocompatibility and Their Application in Bio-Sensing, Bio-Imaging (Volume II)

edited by

and

submission deadline 30 Jun 2025 | 10 articles | Viewed by 19753 | Submission Open

Keywords: fluorescent material; luminescence material; fluorescent probe; fluorescent sensor; biosensor; fluorescent imaging; bioimaging photosensitizer

(This special issue belongs to the Section Biosensor Materials)

Biosensors Based on Self-Assembly and Boronate Affinity Interaction

edited by

Lin Liu

submission deadline 30 Jun 2025 | 5 articles | Viewed by 12795 | Submission Open

Keywords: biosensors; self-assembly; molecular recognition; boronate affinity; metal– organic frameworks; covalent organic frameworks; hydrogen-bonded organic frameworks; organic nanocrystals; aggregation-induced emission

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Surface-Enhanced Raman Scattering in Biosensing Applications

edited by

Hrvoje Gebavi

and

Yuling Hu

submission deadline 30 Jun 2025 | 5 articles | Viewed by 10640 | Submission Open

Keywords: SERS substrate development; SERS for biosensing applications; food contaminant detection; environmental pollution control; machine learning (SERS); SERS sensors; quantitative SERS methods; biohazardous molecules; forensic substances

(This special issue belongs to the Section Optical and Photonic Biosensors)

Electrochemical Biosensing Platforms for Food, Drug and Health Safety

edited by

Mihaela Puiu

submission deadline 30 Jun 2025 | 4 articles | Viewed by 9307 | Submission Open

Keywords: electrochemical bio(immuno)sensing; organic– inorganic hetero-nano-interfaces; early detection; signal amplification; ; conductive nanocomposites; magnetic nanoparticles; nanozymes

(This special issue belongs to the Section Biosensors and Healthcare)

Advanced Lab-on-Chip and Micro-systems for Manipulation and Bio-Detection

edited by

Kai Zhao

and

Kaihuan Zhang

submission deadline 30 Jun 2025 | 1 articles | Viewed by 8685 | Submission Open

Keywords: microfluidics; LOC devices; dielectrophoretic; microfabrication; target manipulation; signal detection; resolution and throughput

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Biosensors for Monitoring and Diagnostics

edited by

Radivoje Prodanović

and

Dalibor M. Stanković

submission deadline 30 Jun 2025 | 7 articles | Viewed by 8467 | Submission Open

Keywords: biosensors; protein engineering; monitoring; biologically active compounds; point of care; bioinformatics

(This special issue belongs to the Section Biosensors and Healthcare)

Optical Biosensor Technology for the Future of Medical Diagnostics and Therapy

edited by

Donato Conteduca

and Isabel Barth

submission deadline 30 Jun 2025 | 2 articles | Viewed by 8330 | Submission Open

Keywords: optical biosensors; nanophotonics; biomedical photonics; integrated biosensors; personalized medicine; medical diagnostics; point-of-care devices

(This special issue belongs to the Section Optical and Photonic Biosensors)

Biosensors Based on Isothermal Nucleic Acid Amplification Strategies

edited by Yongxin Li and

Zewei Luo

submission deadline 30 Jun 2025 | 3 articles | Viewed by 6707 | Submission Open

Keywords: isothermal nucleic acid amplification; nanomaterials; aptamer; public health; environmental monitoring; clinic diagnosis; food safety

(This special issue belongs to the Section Optical and Photonic Biosensors)

Advances in Plasmonic Biosensing Technology

edited by Taerin Chung

submission deadline 30 Jun 2025 | 4 articles | Viewed by 5649 | Submission Open

Keywords: properties of metallic nanostructures; plasmonics-based sensors; surface plasmon resonance (SPR) sensing systems; surface-enhanced Raman scattering (SERS) and biomedical applications; nano-optics; nanophotonics; fabrications of nanostructured substrates; spectroscopies related to plasmonics; single-molecule spectroscopy; single-cell analysis metallomics detection using plasmonics; metal nanoparticle contrast agents for medical diagnostics; metal-enhanced fluorescence MEF; quantum plasmonic sensing and imaging

(This special issue belongs to the Section Biosensor Materials)

Feature Papers of Biosensors

edited by

Jun-Jie Zhu

and Tingting Zheng

submission deadline 30 Jun 2025 | 4 articles | Viewed by 5215 | Submission Open

Keywords: biosensor; fluorescence; Raman; mechanical transducers; microfabrication; mass spectral transducers; wearable device

Electrochemical Sensors and Biosensors for Environmental, Health, and Food Safety Applications (Volume II)

edited by

Stelian Lupu

and

Cecilia Lete

submission deadline 30 Jun 2025 | 3 articles | Viewed by 5117 | Submission Open

Keywords: electrochemical sensors and biosensors; miniaturization and fabrication; environmental monitoring; organic and inorganic pollutants; antioxidants; neurotransmitters; toxins; pharmaceutical contaminants; food safety; in vivo detection; biomarkers

(This special issue belongs to the Section Environmental Biosensors and Biosensing)

Application of Functional Nucleic Acid Based Biosensors in Cell or Tissue Analysis

edited by Fujian Huang

submission deadline 30 Jun 2025 | 2 articles | Viewed by 4349 | Submission Open

Keywords: functional nucleic acids probe; aptamer; DNAzyme; DNA nanostructure; signal amplification; biosensing; cell imaging; tissue analysis; fluorescence signal

(This special issue belongs to the Section Biosensors and Healthcare)

Biosensing Advances in Lateral Flow Assays (LFA)

edited by

John H. T. Luong

submission deadline 30 Jun 2025 | 2 articles | Viewed by 3046 | Submission Open

Keywords: antibody; nucleic acid; molecular imprinted polymer; point-of-care testing; multiplexed assay

(This special issue belongs to the Section Biosensor Materials)

Advances in Two-Dimensional Materials for Electrochemical Biosensors

edited by

Chenhui Yang

Junfeng Zhai

and Yi Tang

submission deadline 30 Jun 2025 | 1 articles | Viewed by 2875 | Submission Open

Keywords: 2D materials; surface engineering; defect engineering; electrochemical biosensors; electrochemical techniques

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Current Perspectives in Biocatalytic Biosensors

edited by

Paolo Bollella

and Angelo Tricase

submission deadline 30 Jun 2025 | 1 articles | Viewed by 2608 | Submission Open

Keywords: enzyme biosensors; smart hydrogels; printed enzymes; catalytic DNA; nanozymes; nanomaterials

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Electrochemical (Bio)Sensors as Promising Analytical Tools in the Analysis of Soils, Plants and Environmental Monitoring

edited by

Stella Girousi

and

Evangelia Golia

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1818 | Submission Open

Keywords: (bio)sensor; electroanalysis; environmental analysis; electrodes; soil; plant

(This special issue belongs to the Section Environmental Biosensors and Biosensing)

Novel Surface Plasmon Resonance Sensing Technologies and Their Applications

edited by

Youjun Zeng

and

Xiantong Yu

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1279 | Submission Open

Keywords: SPR; SPR imaging (SPRi); optical biosensing; microscopy; two-dimensional (2D) nanomaterials

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Fiber Optic Biosensors: Advancements and Applications

edited by Sruthi Prasood Usha

submission deadline 30 Jun 2025 | 1 articles | Viewed by 546 | Submission Open

Keywords: optical fibers; nanostructured configurations and sensing technologies; lab-on-fiber platforms; integration of metasurfaces with fiber optics; biosensors for medical diagnostics; food; water; and air monitoring; diagnostics and imaging; drug delivery and therapy; portable devices; plasmonic sensors; point-of-need/point-of-care systems

(This special issue belongs to the Section Biosensor Materials)

Recent Advancements in Nanomaterials for Biomolecular Monitoring in Miniaturized Sensing Platforms

edited by Tamoghna Saha, Nandhakumar Ponnusamy and Rafael Del Caño Ochoa

submission deadline 30 Jun 2025 | Viewed by 380 | Submission Open

Keywords: biosensors; miniaturized sensing platforms; nanomaterials; redox cycling amplification; synthesis

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

FEAST of Biosensors: Food, Environmental and Cell Sensing Technologies

edited by

Spyridon Kintzios

and

Sofia Mavrikou

submission deadline 30 Jun 2025 | Viewed by 374 | Submission Open

Keywords: artificial intelligence; biosensors; environmental; social; and corporate governance (ESG); OneHealth; 3Rs principle; traceability

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Mass Sensitive Biosensors for Biomedical Applications

edited by

Tibor Hianik

and

Michael Thompson

submission deadline 30 Jun 2025 | Viewed by 229 | Submission Open

Keywords: piezoelectric acoustic wave sensors; surface acoustic wave devices; thickness shear mode biosensor

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

CRISPR-Based Biosensing for Point-of-Care Diagnostics

edited by

Ying Mu

Xiong Ding

and Wenshuai Wu

submission deadline 30 Jun 2025 | Viewed by 213 | Submission Open

Keywords: point-of-care diagnostics; nucleic acid detection; polymerase chain reaction; isothermal amplification; electrochemical analysis; diagnostic materials; diagnostic nanomaterials; microfluidic analysis; chemiluminescence immunoassays; lateral flow immunoassays

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Development of Aggregation-Induced Emission Materials and Their Applications in Biosensing, Bioimaging and Theranostics (2nd Edition)

edited by