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Biosensors publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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CRISPR/Cas-Based Biosensing Systems: Development and Applications—2nd Edition

edited by

Ki Soo Park

submission deadline 20 Jul 2025 | Viewed by 182 | Submission Open

Keywords: nucleic acid nanotechnology; isothermal amplification; molecular diagnostics; immunological diagnostics; point-of-care testing; biosensors; in vitro diagnostics; clinical applications; CRISPR/Cas protein

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Recent Advances in Glucose Biosensors

edited by

Natalija German

and

Anton Popov

submission deadline 25 Jul 2025 | 5 articles | Viewed by 7651 | Submission Open

Keywords: glucose; biosensors; electrochemical biosensors; nanomaterials; biomedical application; disease diagnosis; diabetes mellitus; enzyme; nanotechnology

(This special issue belongs to the Section Biosensors and Healthcare)

Application of Microfluidics in Cell Manipulation and Biosensing

edited by

Yupan Wu

and

Ye Tian

submission deadline 31 Jul 2025 | 9 articles | Viewed by 27922 | Submission Open

Keywords: microfluidic chip; immunoassays; cell manipulation; biosensing; acoustofluidics

(This special issue belongs to the Section Biosensors and Healthcare)

Trends in Development of Biosensors for Disease Diagnosis, Treatment and Management—2nd Edition

edited by

Amir Hatamie

submission deadline 31 Jul 2025 | 6 articles | Viewed by 18900 | Submission Open

Keywords: nanobiosensors for biomedical applications; nanomaterials in biosensors; disease diagnosis; biomarker detection; cellular analysis and diagnostics; point-of-care diagnostics; clinical analysis

(This special issue belongs to the Section Biosensors and Healthcare)

Lab-on-a-Chip Devices for Point-of-Care Diagnostics

edited by Derrick Butler and

Hadar Ben-Yoav

submission deadline 31 Jul 2025 | 5 articles | Viewed by 14743 | Submission Open

Keywords: lab-on-a-chip; point-of-care; diagnostics; biosensor; organ-on-a-chip; microphysiological systems

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Trends and Perspective of Advanced Nanotechnology for Bio-Sensing, Imaging and Cancer Therapy

edited by

Xuemei Wang

and Xiaohui Liu

submission deadline 31 Jul 2025 | 5 articles | Viewed by 13703 | Submission Open

Keywords: advanced nanotechnology; biosensing; multimodal imaging probes; dual-modality/multimodality imaging; artificial intelligence (AI); diagnostic/therapeutic probes; tumor gene/immunotherapy; microfluidic chip

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Advanced SERS Biosensors for Detection and Analysis

edited by Peini Zhao, Lulu Qu and Min Su

submission deadline 31 Jul 2025 | 4 articles | Viewed by 8390 | Submission Open

Keywords: SERS; biosensor; rapid Raman detection; SERS-based sensing materials; point-of-care testing; biochemical analysis

(This special issue belongs to the Section Optical and Photonic Biosensors)

Innovative Strategies for Cancer Biosensing

edited by

Carlos Torres-Torres

and

Blanca Estela García-Pérez

submission deadline 31 Jul 2025 | 5 articles | Viewed by 7898 | Submission Open

Keywords: cancer; cell biology; biosensors; biosignals; instrumentation systems; signal processing; nanoscale effects; immunology

(This special issue belongs to the Section Biosensors and Healthcare)

Recent Advances and Applications of Multiplexed Analysis and Multiplexed Nanobiosensors

edited by

Samuel Adeloju

submission deadline 31 Jul 2025 | 3 articles | Viewed by 7804 | Submission Open

Keywords: multiplex PCR assay; including real-time assay; multiplex tandem PCR; fluorometric immunoassay; multiplex bead-based assay; electrochemiluminescent immunoassay; ELISA-based multiplex method; multiplexed serological assay; multiplexed targeted mass spectrometry assay; SERS-based multiplex biomolecular analysis; CRISPR/Cas multiplexed biosensing; multiplexed electrohydrodynamic biosensor; multiple synchronized biosensors; multiplexed abundance assay; lab-on-chip assay; lateral flow detection; microfluidic array; SERS tags; nanomaterial supported and/or enhanced multiplexing

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Lighting Up Single-Molecule Biosensors and Bioimaging: Now and the Decade to Come

edited by

Pengfei Zhang

and

Yi Chen

submission deadline 31 Jul 2025 | 4 articles | Viewed by 4968 | Submission Open

Keywords: single molecules; biosensing; bioimaging; molecular interaction and recognition; biological behaviors

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Flexible Electronics for Biosensing

edited by

Yuanjing Lin

submission deadline 31 Jul 2025 | 2 articles | Viewed by 4817 | Submission Open

Keywords: biosensing; flexible electronics; wearables; integrated systems; biomarkers analysis; healthcare; environmental monitoring; internet of things

(This special issue belongs to the Section Biosensors and Healthcare)

Paper-Based Biosensing Technologies: From Design to Application

edited by

Surasak Kasetsirikul

submission deadline 31 Jul 2025 | 1 articles | Viewed by 3134 | Submission Open

Keywords: biosensors; paper-based diagnostic devices; point-of-care diagnostic devices; biosensing technologies

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Recent Advances in Biosensors for Pharmaceutical Analysis

edited by

Wuzhen Qi

Zhixin Wang

and Xiuli Zhang

submission deadline 31 Jul 2025 | Viewed by 552 | Submission Open

Keywords: biosensors; microfluidics; organ-on-chip; drug screening; drug quality assessment; drug delivery; pharmacokinetics; toxicological studies

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Recent Advances in Microfluidic Biosensors in Biomedical Applications

edited by

Rohollah Nasiri

submission deadline 31 Jul 2025 | Viewed by 410 | Submission Open

Keywords: microfluidics; electrochemical sensors; optical sensors; wearable sensors; organ on a chip; biosensors; point of care diagnostics; in vitro tissue models; microphysiological sensors; lab-on-a-chip; drug screening

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Application of Polymers in Micro and Nano Biosensors

edited by

Baishali Kanjilal

submission deadline 31 Jul 2025 | Viewed by 364 | Submission Open

Keywords: biosensors; microsensors; nanomaterials; polymers; biopolymers; electrochemical sensors; nanotechnology; nanoparticles; microparticles; environmental sensors

(This special issue belongs to the Section Biosensor Materials)

New Trends in Electrochemical Biosensors for Healthcare and Environmental Monitoring

edited by Pablo R. Dalmasso

submission deadline 31 Jul 2025 | Viewed by 299 | Submission Open

Keywords: biosensors; affinity biosensors; enzymatic biosensors; electrochemical sensing; nanomaterials; surface modification; biomarkers; emerging pollutants

(This special issue belongs to the Section Environmental Biosensors and Biosensing)

Smartphone-Based Biosensor Devices

edited by

Donato Calabria

and

Mara Mirasoli

submission deadline 1 Aug 2025 | 1 articles | Viewed by 689 | Submission Open

Keywords: biosensors; optical biosensing; surface plasmon resonance; fluorescence; (bio)chemiluminescence; colorimetry; electrochemiluminescence; paper-based analytical devices; microfluidics; smartphone-based biosensors; portable devices

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Current Advances in Paper-Based Biosensor Technologies

edited by

Xianbo Lu

and

Moon Il Kim

submission deadline 1 Aug 2025 | Viewed by 137 | Submission Open

Keywords: paper based microfluidic; origami paper based device; colorimetric biosensors; detection of various pathogens and drugs; nanomaterial-integrated device

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Fuel Cell-Based Electrochemical Sensors for Biochemical Detection

edited by

Zhiheng Xu

and

Md Faruk Hossain

submission deadline 1 Aug 2025 | Viewed by 112 | Submission Open

Keywords: fuel cell; electrochemical sensors; biochemical detection; biosensors; healthcare diagnostics; environmental monitoring; food safety

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Recent Progress of In Vitro and In Vivo NanoBiosensors: From Assays, to Diagnostic

edited by

Marita A. Cardoso

Helena M. R. Gonçalves

and

Paula Martins-Lopes

submission deadline 10 Aug 2025 | Viewed by 233 | Submission Open

Keywords: nanotechnology; biotechnology; biosensors; nanomaterials; biomolecules

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Nanotechnology-Based Biosensors in Drug Delivery

edited by

Hossein Hosseinkhani

submission deadline 15 Aug 2025 | 2 articles | Viewed by 3836 | Submission Open

Keywords: biosensor; drug delivery; nanotechnology; biomaterials

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Hydrogel-Based Biosensors: From Design to Applications

edited by

Hongya Geng

Ying Tan

Xin Song

and M. Sundara Ganeasan

submission deadline 15 Aug 2025 | 1 articles | Viewed by 1145 | Submission Open

Keywords: hydrogels; tissue engineering; gels; biosensors

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

2D-Nanomaterials-Based Optical Biosensors

edited by

Leiming Wu

submission deadline 20 Aug 2025 | 1 articles | Viewed by 2889 | Submission Open

Keywords: 2D nanomaterials; optical biosensors; graphene and its derivatives; transition metal dichalcogenides (TMDs); black phosphorus biosensing; surface functionalization; plasmonic biosensors; photonic biosensors; biomedical applications

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Sustainable Green Nanomaterials in Flexible Wearable Devices in SERS and Electrochemical Applications

edited by Ragurethinam Shanmugam, Jeongwoo Park and Manikandan Venkatesan

submission deadline 20 Aug 2025 | Viewed by 188 | Submission Open

Keywords: biosensors; SERS; pollutants; electrochemical sensors; point-of-care devices

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Cellular Sensing and Precision Medicine

edited by

Ning Yang

Yanwei Jia

and Si Chen

submission deadline 25 Aug 2025 | 1 articles | Viewed by 1542 | Submission Open

Keywords: cellular sensing; precision medicine; cytomechanics; bioinformatics; cell communication; drug sensitivity test

(This special issue belongs to the Section Biosensors and Healthcare)

Biosensing Technologies in Medical Diagnosis

edited by Niancai Peng and Fei Hu

submission deadline 31 Aug 2025 | 9 articles | Viewed by 17753 | Submission Open

Keywords: diagnostics; biodetection; biosensors; bioseparation; biomaterial; genomics; nucleic acid detection; immunoassay; wearable medical testing; microfluidics and its application to medical testing; cell analysis; point-of-care testing; drug screening; tissue engineering; regenerative medicine; personalized healthcare

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Optical and Electrochemical Biosensors for Biological, Environmental, and Food Analysis

edited by

Long Wu

submission deadline 31 Aug 2025 | 5 articles | Viewed by 10033 | Submission Open

Keywords: electrode materials; substrate materials; spectroelectrochemical technique; miniaturization; environmental monitoring; biological analysis; food analysis

(This special issue belongs to the Section Optical and Photonic Biosensors)

Wearable Sensors for Precise Exercise Monitoring and Analysis

edited by

Fengyu Li

and

Meng Su

submission deadline 31 Aug 2025 | 4 articles | Viewed by 4325 | Submission Open

Keywords: exercise monitoring; sports analysis; wearable sensors; physical assessment; fatigue detection

(This special issue belongs to the Section Wearable Biosensors)

Biosensor Nanoengineering: Design, Operation and Implementation—2nd Edition

edited by

Dhanjai Dhanjai

and Pramod Kalambate

submission deadline 31 Aug 2025 | 3 articles | Viewed by 3795 | Submission Open

Keywords: nanoengineering; biomaterials; biosensor design and immobilization; biomarkers; smart biosensors; self-powered biosensors; wearable biosensors; plant wearables; AI- and machine learning-enabled biosensors; enzymes; aptamers; and antibodies; stimuli-responsive polymers; three-dimensional-printed sensors

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Advances, Challenges and Opportunities in the Use of 2D Materials for Biosensing and Biomedical Applications

edited by

Cheng-Te Lin

, Chen Ye,

Kunyan Zhang

and Jeewan Ranasinghe

submission deadline 31 Aug 2025 | 2 articles | Viewed by 2582 | Submission Open

Keywords: 2D materials; surface functionalization; point-of-care diagnosis; biocompatibility; molecular recognition; limit of detection; sensitivity; biomarkers

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Programmable Nuclease-Based Biosensors for Medical Diagnostics, Food Safety and Beyond Applications

edited by

Long Ma

, Lijuan Yin and Weipan Peng

submission deadline 31 Aug 2025 | 1 articles | Viewed by 2137 | Submission Open

Keywords: programmable nucleases; CRISPR/Cas; argonaute; biosensor; food safety; medical diagnostics

(This special issue belongs to the Section Biosensor Materials)

Flexible and Stretchable Electronics as Biosensors

edited by

Minqiang Wang

submission deadline 31 Aug 2025 | 2 articles | Viewed by 2087 | Submission Open

Keywords: wearable biosensors; stretchable electronics; nanotechnology; medical devices

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Applications of Cutting-Edge Biosensors in Environment, Food and Healthcare Field

edited by

Ying-Chien Chung

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1777 | Submission Open

Keywords: biosensor; food detection; toxicity detection; tumor markers; neuro-biosensors; genetic biosensors; small RNA biosensor

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Novel (Bio)electroanalytical Methods and Related Outcomes of Antibiotics Determination

edited by

Mihaela Buleandrǎ

and

Dana Elena Popa

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1700 | Submission Open

Keywords: antibiotics; electrochemical (bio)sensors; electroanalysis; redox behavior; electrochemical instrumentation; modified electrodes

Application of Functional Nanomaterials in Photo/Electrical Biosensing

edited by

Yaoguang Wang

and Guanhui Zhao

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1427 | Submission Open

Keywords: biosensing; functional nanomaterials; electrochemical biosensor; electrochemiluminescent biosensor; photoelectrochemical biosensor

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Sensors for Environmental Monitoring and Food Safety—2nd Edition

edited by

Kevin C. Honeychurch

Martina Piano

and David Ferrier

submission deadline 31 Aug 2025 | 1 articles | Viewed by 689 | Submission Open

Keywords: food; beverages; water; air; nanotechnology; enzymes; antibodies; DNA; aptamers; molecularly imprinted polymers; sensors; biosensors

(This special issue belongs to the Section Environmental Biosensors and Biosensing)

Hybrid Conductive Polymer-Based Biosensors: Innovations in Advanced Platforms for Diagnostics and Monitoring

edited by Abijeet S. Mehta

submission deadline 31 Aug 2025 | Viewed by 282 | Submission Open

Keywords: conductive polymers; organic electrochemical transistors (OECTs); CMOS-based image sensors; piezoelectric biosensors; surface plasmon resonance (SPR) sensors; hybrid biosensors; biomedical diagnostics

(This special issue belongs to the Section Biosensor Materials)

Recent Advances in Molecularly Imprinted-Polymer-Based Biosensors

edited by

José Ribeiro

Carlos Pereira

and Manuel A. Azenha

submission deadline 31 Aug 2025 | Viewed by 211 | Submission Open

Keywords: molecularly imprinted polymers (MIPs); imprinted materials; molecular recognition; biomimetic devices; electrochemical sensing; optical sensing; food quality and safety; environmental monitoring; disease biomarkers; biomedical applications; health monitoring

(This special issue belongs to the Section Biosensors and Healthcare)

Non-Invasive Biosensors for Clinical Diagnostics and Healthcare Monitoring

edited by

Pau Redón Lurbe

submission deadline 31 Aug 2025 | Viewed by 192 | Submission Open

Keywords: non-invasive biosensors; clinical diagnostics; healthcare monitoring; machine learning (ML); artificial intelligence (AI)

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

AI-Driven Photonic Biosensors: Revolutionizing Human Behavioral Pattern Detection and Advanced Applications

edited by

Dror Malka

submission deadline 15 Sep 2025 | Viewed by 185 | Submission Open

Keywords: photonic waveguide biosensors; refractive index sensing; lab-on-chip; optical biosensing; biomedical diagnostics; integrated optics; environmental monitoring; real-time detection; food safety; portable biosensors; mind-wandering detection; EEG-based monitoring; artificial intelligence (AI); machine learning; convolutional neural networks (CNNs); deep learning; MRI image processing; cognitive state detection; photonic neural networks; biosensing technologies; medical imaging; brain– computer interfaces (BCIs); cognitive load analysis; non-invasive diagnostics; neuro-photonic chips

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Microfluidic Systems and Computational Imaging Methods in Lab-on-a-Chip Technologies

edited by

Maide Bucolo

Massimo Camarda

and

Pasquale Memmolo

submission deadline 20 Sep 2025 | 4 articles | Viewed by 12379 | Submission Open

Keywords: cell manipution and sorting; complex flow in biomicrofluidics; image and signal processing in bio-chip; artificial-inteligence-powered systems; computational microscopy; micro-fabrication and advanced materials; embedded systems; dielectrophoresis; electrophoresis; hydrofocusing

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Advanced Electrochemical Biosensors and Their Applications

edited by

Matias Regiart

Walter Ricardo Brito

and

Martín A. Fernández-Baldo

submission deadline 20 Sep 2025 | 3 articles | Viewed by 4110 | Submission Open

Keywords: electrochemical; nanotechnology; sensors; microfluidics; biosensing; nanomaterials; biosensors

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Advanced Biosensors for Disease Screening, Monitoring, Diagnosis and Treatment

edited by

Ronny Priefer

submission deadline 30 Sep 2025 | 5 articles | Viewed by 8892 | Submission Open

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Recent Advances and Perspectives of Fluorescent Biosensors

edited by Miho Suzuki and Yutaka Shindo

submission deadline 30 Sep 2025 | 4 articles | Viewed by 8443 | Submission Open

Keywords: fluorescent sensor; ratiometric sensor; fluorescent protein; synthetic probe; quantum dot; optogenetic reporter; genetically encoded probe; live imaging; FRET; FLIM; FCS; aggregation-induced emission

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Nanomaterial-Enhanced Biosensing for Point-of-Care Diagnostics

edited by

Pramod Gupta

, Prabir Kumar Kulabhusan and Debasis Maity

submission deadline 30 Sep 2025 | 4 articles | Viewed by 5911 | Submission Open

Keywords: nanomaterials; biosensing; point-of-care diagnostics; nanoparticles; microfluidics; clinical applications; electrochemical sensors; lab-on-a-chip; portable devices; early diagnosis

(This special issue belongs to the Section Biosensor Materials)

Implantable, Wireless Biosensors and Biodevices for Neuroscience Research, 2nd Edition

edited by

Jiayi Zhang

David A. Borton

and Ming Yin

submission deadline 30 Sep 2025 | 1 articles | Viewed by 4999 | Submission Open

Keywords: implantable; wireless; neurosensing; neuromodulation; biodevices; low power; biocompatibility; bidirectional interfaces

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Biosensors for Organ-on-Chip Devices

edited by Danial Khorsandi

submission deadline 30 Sep 2025 | 2 articles | Viewed by 4014 | Submission Open

Keywords: organ-on-chip; biosensors; microfluidics; real-time monitoring; label-free detection; drug discovery; toxicity testing; disease modeling; biochemical sensors; biophysical sensors; multiplexed biosensing

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Biosensors for Environmental Monitoring and Food Safety

edited by

Jing Wei

and Bingxi Feng

submission deadline 30 Sep 2025 | 2 articles | Viewed by 2919 | Submission Open

Keywords: biosensors; nanozyme; nanomaterials; metal oxide; catalysis; environmental monitoring; food safety

(This special issue belongs to the Section Environmental Biosensors and Biosensing)

Novel Graphene-Based Biosensors for Biomedical Applications

edited by

Sabina Żołędowska

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1917 | Submission Open

Keywords: biosensors; graphene; biomedical applications; electrochemical sensing; surface modification; sensing mechanisms; transduction principles; medical diagnostics; point-of-care testing; biomarker detection; drug discovery; functionalization; nanoparticle integration; sensitivity; specificity; stability; performance evaluation; validation; biocompatibility; clinical translation

(This special issue belongs to the Section Biosensors and Healthcare)

Electrochemical DNA Biosensors

edited by