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Biosensors publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Surface-Enhanced Raman Scattering Biosensors—2nd Edition

edited by

Nicoleta Elena Dina

submission deadline 30 Oct 2025 | 1 articles | Viewed by 2948 | Submission Open

Keywords: SERS; biosensing; miniaturized devices; PoC devices; clinical applications of SERS; SERS-based diagnosis

(This special issue belongs to the Section Optical and Photonic Biosensors)

Advances in Portable and Wearable Sensing Systems for Biochemical Monitoring

edited by

Yanli Lu

and

Zetao Chen

submission deadline 31 Oct 2025 | 11 articles | Viewed by 33992 | Submission Open

Keywords: portable sensing system; wearable system; bioelectronics; biochemical monitoring; self-powered biosensors; in situ biosensing; epidermal patches; implantable sensors; ingestible sensors; biosensors

(This special issue belongs to the Section Wearable Biosensors)

Biosensors Based on Transistors

edited by

Kihyun Kim

and

Meyya Meyyappan

submission deadline 31 Oct 2025 | 7 articles | Viewed by 18458 | Submission Open

Keywords: biosensors; field-effect transistors; BioFETs; electrolyte-gated transistor; flexible biosensor; biomarkers; surface functionalization; diagnostics; point-of-care; clinical applications

(This special issue belongs to the Section Biosensors and Healthcare)

Miniature Sensors Based on Highly Efficient Chemical and Biological Sensing Interfaces

edited by

Ji Qi

and Hongki Kim

submission deadline 31 Oct 2025 | 10 articles | Viewed by 13327 | Submission Open

Keywords: chemical (bio) sensors; paper-based device; portable device; lab on a chip; enzyme-linked immunosorbent assay (ELISA); nanomaterial; molecularly imprinted polymer (MIP); electrochemical analysis; surface-enhanced Raman scattering (SERS); fluorescence; point of care testing (POCT)

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

DNA Molecular Engineering-Based Biosensors

edited by Yifan Lyu

submission deadline 31 Oct 2025 | 4 articles | Viewed by 9220 | Submission Open

Keywords: biosensors; DNA nanotechnology; molecular diagnosis; bioimaging; bioanalysis; functional nucleic acid; aptamers

(This special issue belongs to the Section Biosensors and Healthcare)

Biosensing Applications for Cell Monitoring

edited by Youngdae Yoon

submission deadline 31 Oct 2025 | 5 articles | Viewed by 8429 | Submission Open

Keywords: biosensors; cell monitoring; point-of-care; pathogen; biosensing devices; rapid detection; diagnosis

(This special issue belongs to the Section Biosensors and Healthcare)

Advances in Nanozyme-Based Biosensors

edited by

Jiaojiao Zhou

and

Xiangheng Niu

submission deadline 31 Oct 2025 | 3 articles | Viewed by 6684 | Submission Open

Keywords: nanozymes; biosensor; bioimaging; nanozyme-based aptasensor; nanozyme-involved immunoassay; food analysis; environmental detection; nanozyme-based biochemical analysis

(This special issue belongs to the Section Biosensor Materials)

Innovations in Neurochemical and Electrophysiological Sensing: Materials, Devices, and Techniques

edited by

Elisa Castagnola

and

Wen Li

submission deadline 31 Oct 2025 | 1 articles | Viewed by 6041 | Submission Open

Keywords: electrochemical sensors; neural interfaces; fast scan cyclic voltammetry; neurotransmitters

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Application of Nanocomposites for Biosensors

edited by

Paulo A. Raymundo-Pereira

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1906 | Submission Open

Keywords: nanocomposites; biosensors; point-of-care diagnostics; biomolecule detection; biocompatibility; wearables devices; nanomaterials; DNA detection; plant sensors; protein sensors; electrochemical sensors; personalized medicine; therapeutic drug monitoring; diagnosis; biomarkers; biomimetic materials; bioinspired materials; food safety; environmental monitoring; precision agriculture; quality control; security; biomedical; emerging pollutants

(This special issue belongs to the Section Biosensors and Healthcare)

Recent Advances in Biosensor-Integrated Organ-on-a-Chip Technologies for Diagnostics and Therapeutics

edited by

Giuseppe Maruccio

and

Yangzhi Zhu

submission deadline 31 Oct 2025 | Viewed by 310 | Submission Open

Keywords: biosensor; organ-on-a-chip; diagnostics; therapeutics

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Microfluidic Sensors for Biomedical Application

edited by Dan Yuan

submission deadline 31 Oct 2025 | Viewed by 228 | Submission Open

Keywords: microfluidics; lab-on-a-chip; point-of-care diagnostics; organ-on-a-chip; biomedical applications; drug delivery systems; high-throughput screening; biosensors

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Emerging Innovative Approaches in Magnetic Sensor Development for Biosensing Applications

edited by

Antonio Hernando Grande

and

Daniel Matatagui

submission deadline 31 Oct 2025 | Viewed by 168 | Submission Open

Keywords: sensors; biosensors; magnetic; modelling; simulation; synthesis; nanotechnology; bioconjugation; functionalization; magnetostrictive; magnetoresistive; magnetic resonance; wireless sensors

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

The Emerging Techniques in Biosensors and Bioelectronics

edited by

Shunbo Li

submission deadline 1 Nov 2025 | 3 articles | Viewed by 7727 | Submission Open

Keywords: biosensors; nanotechnology; micro/nanofluidics; wearable devices; artificial intelligence

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Wearable Biosensors and Health Monitoring

edited by Xiaoxiang Gao and

Zhengchun Liu

submission deadline 1 Nov 2025 | 4 articles | Viewed by 4851 | Submission Open

Keywords: wearable biosensors; flexible and stretchable bioelectronics; AI in wearable biosensing; multimodal wearable biosensing; multimodal/multifunctional wearable biosensing; biocompatible materials; biosensing textiles; biofunctionalized surfaces; smart materials; graphene-based sensors; sensor integration; human– computer interactions; remote patient monitoring; wearable energy sources; signal processing algorithms; Internet of Diseases (IoD)

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Electrochemical Biosensors in Healthcare Services

edited by

Qurat ul ain Zahra

and

Imran Mahmood Khan

submission deadline 1 Nov 2025 | Viewed by 263 | Submission Open

Keywords: electrochemical biosensors; point-of-care diagnostics; wearable and implantable biosensors; nanomaterials in biosensing; lab-on-a-chip technology; chronic disease monitoring; healthcare biosensing; biomarker detection; AI-driven biosensor analytics; personalized medicine

(This special issue belongs to the Section Biosensors and Healthcare)

Aptamer-Based Biosensors for Point-of-Care Diagnostics

edited by

Ana Díaz-Fernández

and

Cecilia Cristea

submission deadline 15 Nov 2025 | 7 articles | Viewed by 11327 | Submission Open

Keywords: aptamer; biosensor; point of care; SELEX; diagnostics; precision medicine

(This special issue belongs to the Section Biosensor Materials)

Advanced Microfluidic Devices and Lab-on-Chip (Bio)sensors

edited by

Pablo Giménez-Gómez

and

Roberto Pilloton

submission deadline 20 Nov 2025 | 7 articles | Viewed by 21275 | Submission Open

Keywords: microfluidics; lab-on-chip; (bio)sensing; integrated systems; point-of-care; point-of-need

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Biosensors Based on Microfluidic Devices—2nd Edition

edited by

Jun Yang

and

Ning Hu

submission deadline 25 Nov 2025 | 11 articles | Viewed by 20308 | Submission Open

Keywords: microfluidics; biosensing; surface plasmon resonance; electrochemical; surfaced-enhanced Raman scattering; portable devices; point-of-care testing; liquid crystal

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Micro/Nanofluidic System-Based Biosensors

edited by

Mengren Wu

Yuan Gao

and

Yang Lin

submission deadline 25 Nov 2025 | 2 articles | Viewed by 6458 | Submission Open

Keywords: microfluidics; nanofluidics; biomarkers; pathogens; pollutants; single cell

(This special issue belongs to the Section Biosensor Materials)

Novel Designs and Applications for Electrochemical Biosensors

edited by Defang Liu and

Kevin C. Honeychurch

submission deadline 25 Nov 2025 | 4 articles | Viewed by 4566 | Submission Open

Keywords: electrochemical; biosensors; electrochemical analysis; nanomaterial; electrochemiluminescence; immunosensor

(This special issue belongs to the Section Biosensor Materials)

Nano/Micro Biosensors for Biomedical Applications (2nd Edition)

edited by

Jin-Ho Lee

and

Ki Su Kim

submission deadline 30 Nov 2025 | 7 articles | Viewed by 16584 | Submission Open

Keywords: biosensors; nano/micromaterials; microsystem; physical; chemical; electrical; electrochemical

(This special issue belongs to the Section Biosensors and Healthcare)

Microfluidics and Organ-on-a-Chip for Disease Modeling and Drug Screening (2nd Edition)

edited by

Rohollah Nasiri

and Mohammadreza Nikmaneshi

submission deadline 30 Nov 2025 | 5 articles | Viewed by 13505 | Submission Open

Keywords: in vitro tissue models; microfluidics; organ on a chip; sensors; microphysiological sensors; lab-on-a-chip; drug screening; disease modeling; 3D bioprinting

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Biosensors for Food Safety

edited by

Ramaraja Ramasamy

, José I. Reyes-De-Corcuera and

Baviththira Suganthan

submission deadline 30 Nov 2025 | 5 articles | Viewed by 10245 | Submission Open

Keywords: bacteria; toxins; pesticidal residue/pesticides; fertilizers; fungus; viruses; food borne pathogens; biosensors; microfluidics

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Nanomaterial-Based Biosensors for Point-of-Care Testing

edited by

Samir Kumar

Satyendra Kumar Mishra

and

Sachin Gupta

submission deadline 30 Nov 2025 | 7 articles | Viewed by 5844 | Submission Open

Keywords: nanomaterials; point-of-care testing (POCT); gold/silver nanoparticles; quantum dots; carbon nanomaterials; optical biosensors; electrochemical biosensors; piezoelectric biosensors; magnetic biosensors; colorimetric biosensors

(This special issue belongs to the Section Biosensor Materials)

Organic Two-Dimensional Material: Synthesis and Biosensing Applications

edited by

Shengbin Lei

submission deadline 30 Nov 2025 | 2 articles | Viewed by 4230 | Submission Open

Keywords: organic two-dimensional materials; biosensor; thin films; field effect transistors; synthesis

(This special issue belongs to the Section Biosensor Materials)

Recent Developments in Micro/Nano Sensors for Biomedical Applications

edited by Federico Mazur and

Elder De la Rosa Cruz

submission deadline 30 Nov 2025 | 3 articles | Viewed by 4040 | Submission Open

Keywords: micro/nanosensors; early diagnostics; lab-on-a-chip systems; microfluidics; real-time therapeutic monitoring; nanomaterials; clinical translation; digital health platforms; biomedical

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

The Application of Biomaterials in Electronics and Biosensors

edited by

Byungil Hwang

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2803 | Submission Open

Keywords: biomaterials; electronics; biosensors; biocompatibility; sustainable technology; wearable technology; health monitoring; environmental sensing; fabrication techniques; interdisciplinary research

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Advances in Flexible and Wearable Biosensors

edited by Zhenghan Shi

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2697 | Submission Open

Keywords: flexible biosensors; wearable biosensors; flexible electronics; multimodal biosensing; biofluid analysis; biochemical detection; non-invasive diagnostics; wearable health monitoring; point-of-care testing (POCT); personalized healthcare

(This special issue belongs to the Section Biosensors and Healthcare)

Electrochemical Biosensor Applications in Agriculture, Environment and Health Systems

edited by

Fernando Javier Arévalo

and Adrián Marcelo Granero

submission deadline 30 Nov 2025 | 3 articles | Viewed by 2043 | Submission Open

Keywords: biosensors; biological materials; synthetic materials; agriculture systems; environmental systems; health systems

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Artificial Intelligence (AI) and Machine Learning (ML) in Biosensors: Innovation, Application, and Challenge

edited by

Li Ren

and

Benoît Piro

submission deadline 1 Dec 2025 | 5 articles | Viewed by 5915 | Submission Open

Keywords: biosensors; artificial intelligence; machine learning; precision medicine; biomarkers; point-of-care testing; digital health; smart connected healthcare; quality assessment and monitoring; diagnosis and prognosis

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

New Material-Based Biosensors

edited by

Mingfei Pan

Longhua Xu

and Gaoshuang Hu

submission deadline 1 Dec 2025 | Viewed by 313 | Submission Open

Keywords: matrix effect analysis; food quality and safety; nanomaterials; immunoassay; immunochromatography; molecular imprinting technique; multiple residue detection; multimode detection; visual detection; paper-based sensor

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

The Research and Application of Lateral Flow Biosensors

edited by Guodong Liu

submission deadline 1 Dec 2025 | Viewed by 143 | Submission Open

Keywords: lateral flow biosensors; point-of-care; microfluidics; CRISPR; EXPAR; RPA; LAMP; aptamers; peptides; nucleic acid signal amplification

(This special issue belongs to the Section Biosensors and Healthcare)

Aptamer-Based Sensing: Designs and Applications

edited by

Tao Le

submission deadline 15 Dec 2025 | 4 articles | Viewed by 5131 | Submission Open

Keywords: aptamer; aptasensor; DNA; RNA; screening; point of care; SELEX; diagnostics

(This special issue belongs to the Section Biosensor Materials)

Biosensing and Diagnosis—2nd Edition

edited by

Jiyang Liu

submission deadline 20 Dec 2025 | 8 articles | Viewed by 10784 | Submission Open

Keywords: point-of-care testing; biosensing device; biochemical analysis; diagnostics; biosensor; biosensing; bioimaging

(This special issue belongs to the Section Biosensors and Healthcare)

Sensors for Detection of Virus and Bacteria

edited by

Zhu Chen

submission deadline 20 Dec 2025 | Viewed by 277 | Submission Open

Keywords: bacteria and viruses; nanomaterials; molecular diagnostics; microfluidics and microsystem; artificial intelligence; electrochemical biosensors; optical chemical biosensor

New Progress in Optical Fiber-Based Biosensors—2nd Edition

edited by

Arnaldo Leal-Junior

and

Camilo A.R. Díaz

submission deadline 25 Dec 2025 | 3 articles | Viewed by 3862 | Submission Open

Keywords: optical fiber biosensors; surface plasmon resonance (SPR); localized surface plasmon resonance (LSPR); evanescent field; grating-based sensors; interferometer-based sensors; point-of-care sensors; nanophotonics; surface-enhanced Raman scattering (SERS)

(This special issue belongs to the Section Optical and Photonic Biosensors)

Aptamer-Based Nanosensing Strategy and Applications

edited by

Li Gao

and Jingjie Cui

submission deadline 25 Dec 2025 | 3 articles | Viewed by 3582 | Submission Open

Keywords: aptamers; aptasensor; biosensor; nucleic acid; nucleic acid probe; DNA/RNA; DNA nanostructure

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Molecularly Imprinted Polymers in Biosensors: Assembly, Characterization and Applications

edited by Maria Goreti Ferreira Sales,

Jordi Riu

and

Manuela F. Frasco

submission deadline 25 Dec 2025 | 2 articles | Viewed by 1791 | Submission Open

Keywords: molecularly imprinted polymers; biosensors; electropolymerisation; UV-initiated polymerisation; food analysis; environmental analysis; industrial follow-up; health diagnostics; biomimetic; paper-based analytical devices; lateral flow tests; microfluidics; electrochemical detection; optical detection

(This special issue belongs to the Section Optical and Photonic Biosensors)

Advanced Optical Methods for Biosensing

edited by

Pinkie Jacob Eravuchira

Chih-Tsung Yang

and

Nathan Lindquist

submission deadline 31 Dec 2025 | 10 articles | Viewed by 19117 | Submission Open

Keywords: optical biosensors; lab-on-a-chip; point-care devices; mi-crofluidics

(This special issue belongs to the Section Optical and Photonic Biosensors)

Material-Based Biosensors and Biosensing Strategies

edited by

Huanyu Cheng

Cheng-Te Lin

and

Yige Zhou

submission deadline 31 Dec 2025 | 5 articles | Viewed by 13511 | Submission Open

Keywords: biosensor; bioelectronics; Lab-on-a-Chip; nanomaterials; polymer

(This special issue belongs to the Section Biosensor Materials)

Advanced Biosensors and Bioelectronics: From Liquid Metal-Based to Flexible Devices

edited by

Rui Guo

and

Xuyang Sun

submission deadline 31 Dec 2025 | 2 articles | Viewed by 11811 | Submission Open

Keywords: liquid metal; biosensors; flexible electronics

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

CRISPR/Cas System-Based Biosensors

edited by

Shiping Song

and Jing Su

submission deadline 31 Dec 2025 | 3 articles | Viewed by 9473 | Submission Open

Keywords: CRISPR/Cas system; biosensor; biochip; lab on a chip; portable biosensing device; wearable biosensing device; POCT; disease diagnosis

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Recent Advances in Nanomaterial-Based Biosensing and Diagnosis

edited by

Kang Cui

and

Yizhong Huang

submission deadline 31 Dec 2025 | 2 articles | Viewed by 8727 | Submission Open

Keywords: nanomaterials; biosensors; biosensing; health biomarker; point-of-care testing; bioimaging; diagnosis

(This special issue belongs to the Section Biosensor Materials)

Bioluminescent and Fluorescent Microbial Biosensors: Honoring Prof. Shimshon Belkin’s Contributions to the Field

edited by

Robert Steven Marks

, Kun Jia,

Evgeni Eltzov

and Boris Polyak

submission deadline 31 Dec 2025 | 3 articles | Viewed by 8661 | Submission Open

Keywords: bioluminescence; bioreporters; biosensors; applications; commercialization

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Cell-Based Biosensors for Rapid Detection and Monitoring (2nd Edition)

edited by

Georgia Moschopoulou

submission deadline 31 Dec 2025 | 7 articles | Viewed by 8617 | Submission Open

Keywords: analytical devices; bioelectric; cell-based biosensors; enviromental pollutants; food safety; impedimetric biosensors; medical diagnostics; microbial fuel cells; toxicology; synthetic cells

(This special issue belongs to the Section Biosensors and Healthcare)

Advancements in Molecular Diagnostics and Biosensing: Harnessing the Power of FRET Technology

edited by Xue Qiu and

Jiajia Guo

submission deadline 31 Dec 2025 | 5 articles | Viewed by 8085 | Submission Open

Keywords: FRET; smFRET; time-resolved FRET; molecular diagnostics; molecular interaction dymamics

(This special issue belongs to the Section Optical and Photonic Biosensors)

Photonics for Bioapplications: Sensors and Technology—2nd Edition

edited by

Nélia Jordão Alberto

Maria de Fátima Domingues

Nunzio Cennamo

and

Adriana Borriello

submission deadline 31 Dec 2025 | 6 articles | Viewed by 7721 | Submission Open

Keywords: optical fiber biosensing; optical fiber immunosensors; new bio/chemical probes for bioapplications; molecular diagnosis; point-of-care devices; biomarker detection; wearable biomedical sensors; optical sensors in e-Health architectures; energy-efficient eHealth architecture; big data analysis for eHealth; plasmonic sensors and interrogation systems; advanced signal processing techniques; photonic integrated circuits (PICs) for bioapplications; imaging sensors; low-cost; miniaturized; selective; and multiparameter photonic devices

(This special issue belongs to the Section Optical and Photonic Biosensors)

Biophysical Sensors for Biomedical/Health Monitoring Applications (2nd Edition)

edited by

Sang Min Won

submission deadline 31 Dec 2025 | 2 articles | Viewed by 7255 | Submission Open

Keywords: biophysical sensor; flexible device; biointegrated electronics; stretchable microsystem; implantable electronics; biomedical device; health monitoring

(This special issue belongs to the Section Biosensors and Healthcare)

Recent Developments in Nanomaterial-Based Electrochemical Biosensors

edited by

Fei Yan

submission deadline 31 Dec 2025 | 4 articles | Viewed by 6879 | Submission Open

Keywords: nanomaterials; electrochemical biosensors; clincial samples anaysis; portable detection; small molecule metabolites; pharmaceutical analysis; pathogen detection; toxin analysis biomarkers detection

(This special issue belongs to the Section Biosensors and Healthcare)