Improving Biosensor Performance Using Surface Chemistry
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Nano- and Micro-Technologies in Biosensors".
Deadline for manuscript submissions: 31 July 2026 | Viewed by 41
Special Issue Editor
Special Issue Information
Dear Colleagues,
Although many biosensors perform well in buffer solutions and research laboratory settings, transitioning to messier biological materials in clinical laboratories can often be challenging. Biological materials are full of other proteins, lipids, and even whole cells, which can interfere with sensor performance. Non-specific adsorption from these unwanted compounds can mask the sensor signal, block biomarker binding sites, and cause false negatives to be registered, greatly reducing biosensor performance in biological media. A variety of surface chemistries, surface coatings, and bio-interfaces have been developed to reduce non-specific adsorption and improve biosensor performance. In this Special Issue, we aim to collect a series of papers on unique and high-performing surface modifications and interfaces that improve biosensor performance, and allow biosensors to be used in real clinical samples, as well as in other areas such as water monitoring or food safety. These techniques are crucial to allowing biosensors to be used in real-world samples, and as such, we believe it is important to highlight new advances in biosensor surface chemistries to improve performance.
Dr. Brian De La Franier
Guest Editor
Manuscript Submission Information
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Keywords
- surface chemistry
- surface functionalization
- biointerfaces
- anti-fouling strategies
- non-specific adsorption
- clinical diagnostics
- biological monitoring
- biosensor performance
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