Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
6.6
4.9
Journals
Biosensors
Special Issues
Biosensor Nanoengineering: Design, Operation and Implementation—2nd Edition
share announcement

Biosensor Nanoengineering: Design, Operation and Implementation—2nd Edition

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 3082

Special Issue Editors

Dr. Dhanjai Dhanjai

E-Mail Website
Guest Editor
Department of Chemistry, University of Allahabad, Prayagraj, India
Interests: nanoengineering; biomaterials; stimuli responsive polymers
Special Issues, Collections and Topics in MDPI journals
Dr. Pramod Kalambate

E-Mail Website
Guest Editor
Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, Waterloo, ON, Canada
Interests: 2D materials; MXenes; biosensors; portable sensors; energy storage

Special Issue Information

Dear Colleagues,

This Special Issue will focus on biosensors’ nanoengineering design and real-time operation and their use to solve real-life problems in the whole ecosystem. This Special Issue will study the nanoengineering of biomaterials and nanomaterials and their interactions to develop state-of-the-art nanostructures, systems, and devices to be used as sensing/biosensing tools. There are many challenges related to the real-time implementation of biosensors such as poor stability, low specificity, the poor sensing performances of materials, and environmental sensitivity. The use of artificial intelligence and machine learning will further result in the rapid interpretation of data prediction and implementation of developed biosensing devices in real-time situations. These developments will lead to more realistic technical solutions to emerging global concerns such as food safety, environmental protection, and healthcare monitoring.

For this Special Issue, we invite contributions that promise to lead to significant advancements in the field of biosensor technologies with regard to food safety, environmental protection, social security, and healthcare monitoring.

Contributions and critical reviews on recent developments in the above-mentioned topics are most welcome.

Dr. Dhanjai Dhanjai
Dr. Pramod Kalambate
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanoengineering
  • biomaterials
  • biosensor design and immobilization
  • biomarkers
  • smart biosensors
  • self-powered biosensors
  • wearable biosensors
  • plant wearables
  • AI- and machine learning-enabled biosensors
  • enzymes, aptamers, and antibodies
  • stimuli-responsive polymers
  • three-dimensional-printed sensors

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (3 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

16 pages, 9618 KiB  
Article
Copper Hexacyanoferrates Obtained via Flavocytochrome b2 Assistance: Characterization and Application
by Galina Gayda, Olha Demkiv, Nataliya Stasyuk, Halyna Klepach, Roman Serkiz, Faina Nakonechny, Mykhailo Gonchar and Marina Nisnevitch
Biosensors 2025, 15(3), 157; https://doi.org/10.3390/bios15030157 - 2 Mar 2025
Cited by 1 | Viewed by 697
Abstract
Artificial enzymes or nanozymes (NZs) are gaining significant attention in biotechnology due to their stability and cost-effectiveness. NZs can offer several advantages over natural enzymes, such as enhanced stability under harsh conditions, longer shelf life, and reduced production costs. The booming interest in [...] Read more.
Artificial enzymes or nanozymes (NZs) are gaining significant attention in biotechnology due to their stability and cost-effectiveness. NZs can offer several advantages over natural enzymes, such as enhanced stability under harsh conditions, longer shelf life, and reduced production costs. The booming interest in NZs is likely to continue as their potential applications expand. In our previous studies, we reported the “green” synthesis of copper hexacyanoferrate (gCuHCF) using the oxidoreductase flavocytochrome b2 (Fcb2). Organic–inorganic micro-nanoparticles were characterized in detail, including their structure, composition, catalytic activity, and electron-mediator properties. An SEM analysis revealed that gCuHCF possesses a flower-like structure well-suited for concentrating and stabilizing Fcb2. As an effective peroxidase (PO) mimic, gCuHCF has been successfully employed for H2O2 detection in amperometric sensors and in several oxidase-based biosensors. In the current study, we demonstrated the uniqueness of gCuHCF that lies in its multifunctionality, serving as a PO mimic, a chemosensor for ammonium ions, a biosensor for L-lactate, and exhibiting perovskite-like properties. This exceptional ability of gCuHCF to enhance fluorescence under blue light irradiation is being reported for the first time. Using gCuHCF as a PO-like NZ, novel oxidase-based sensors were developed, including an optical biosensor for L-arginine analysis and electrochemical biosensors for methanol and glycerol determination. Thus, gCuHCF, synthesized via Fcb2, presents a promising platform for the development of amperometric and optical biosensors, bioreactors, biofuel cells, solar cells, and other advanced devices. The innovative approach of utilizing biocatalysts for nanoparticle synthesis highlights a groundbreaking direction in materials science and biotechnology. Full article
(This article belongs to the Special Issue Biosensor Nanoengineering: Design, Operation and Implementation—2nd Edition)
►▼ Show Figures

Figure 1

14 pages, 3844 KiB  
Communication
Development of a Mass-Producible Microfluidic Device for Single and Bulk Mycobacteria Investigations
by Adrian J. T. Teo, Jianhui Gu, Alexander Govyadinov, Pavel Kornilovitch, Peiyun Wang, Serene Goh, Nguyen Truong Tung, Zhen Peng, Keith Koh and King Ho Holden Li
Biosensors 2025, 15(2), 108; https://doi.org/10.3390/bios15020108 - 13 Feb 2025
Viewed by 922
Abstract
We developed a mass-producible microfluidic device capable of long-term observations of single bacilli and bulk bacteria culture interactions for subsequent antimicrobial resistance (AMR) studies. The device provides high consistency across separate devices due to its standardized manufacturing process unlike conventional microfluidic devices. Mycobacteria [...] Read more.
We developed a mass-producible microfluidic device capable of long-term observations of single bacilli and bulk bacteria culture interactions for subsequent antimicrobial resistance (AMR) studies. The device provides high consistency across separate devices due to its standardized manufacturing process unlike conventional microfluidic devices. Mycobacteria bovis BCG and M. smegmatis are trapped within the microfluidic device using minimal equipment and capillary-based techniques, acting as a surrogate model for the highly pathogenic bacteria M. tuberculosis. Individual bacilli and bulk bacteria aggregates were observed across a span of ten growth cycles, revealing bacteria growth morphologies alike those in past research. We accordingly propose that this chip would be appropriate for observations of AMR trials involving M. tuberculosis. Full article
(This article belongs to the Special Issue Biosensor Nanoengineering: Design, Operation and Implementation—2nd Edition)
►▼ Show Figures

Figure 1

13 pages, 2187 KiB  
Article
An Innovative Enzymatic Surface Plasmon Resonance-Based Biosensor Designed for Precise Detection of Glycine Amino Acid
by Gabriela Elizabeth Quintanilla-Villanueva, Osvaldo Rodríguez-Quiroz, Araceli Sánchez-Álvarez, José Manuel Rodríguez-Delgado, Juan Francisco Villarreal-Chiu, Donato Luna-Moreno and Melissa Marlene Rodríguez-Delgado
Biosensors 2025, 15(2), 81; https://doi.org/10.3390/bios15020081 - 1 Feb 2025
Cited by 1 | Viewed by 1054
Abstract
Glycine is an essential amino acid involved in synthesizing a variety of important biomolecules, and its concentration can influence numerous biochemical processes, including the severity of symptoms in a wide range of conditions in humans, such as cancer, schizophrenia, major depression, and diabetes. [...] Read more.
Glycine is an essential amino acid involved in synthesizing a variety of important biomolecules, and its concentration can influence numerous biochemical processes, including the severity of symptoms in a wide range of conditions in humans, such as cancer, schizophrenia, major depression, and diabetes. While a few costly or labour-intensive methods are currently available, we have developed a new enzymatic biosensor that can accurately measure glycine levels with remarkable simplicity. By employing immobilized laccase enzymes in combination with a surface plasmon resonance (SPR) device, our system achieved a limit of detection (LOD) of 9.95 mM and a limit of quantification (LOQ) of 33.19 mM. In addition, it demonstrated a recovery rate of 97.64 ± 7.71%. Moreover, the biosensor maintained consistent signal intensity over 21 days and supported a total of 60 analyses using the same immobilized enzyme setup, demonstrating excellent reusability. Notably, this study marks the first time glycine has been determined using an enzymatic SPR-based platform. Full article
(This article belongs to the Special Issue Biosensor Nanoengineering: Design, Operation and Implementation—2nd Edition)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-3
Back to TopTop