Advanced Nanomaterials for Electrochemical Biosensing Application—2nd Edition

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: 31 July 2026 | Viewed by 2161

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Department of Electronic Engineering, Gachon University, Seongnam 13120, Gyeonggi-Do, Republic of Korea
Interests: electrochemical biosensors
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Special Issue Information

Dear Colleagues,

Sustainable and multifunctional nanostructured advanced materials are significantly growing in importance due to their unique physio-chemical properties. Thus, attention has been drawn to their use in fabricating electrochemical sensors, which have persistently evolved in the fields of food management, environmental monitoring, disease diagnosis, and miniaturized devices. Utilizing state-of-the-art technology for synthesizing multifunctional nanostructured materials has opened up new pathways which allow for the simultaneous detection of various biomolecular signals. Electrochemical detection methods have shown great benefits compared to their counterparts, such as high sensitivity, high selectivity, rapid response, and affordability. Sustainable and multifunctional nanostructured materials coupled with electrochemical, liquid-gated, back-gated, dual-gated, and impedimetric methods have shown promise in the detection of biomolecular signals. In this Special Issue, we welcome original research articles, short communications, and review articles from researchers, focussing on the following topics:

  • New strategies for sustainable synthesis of nanostructured materials for electrochemical and impedimetric detection.
  • New strategies for the design and development of electrode fabrication techniques based on new advanced materials for biomolecule detection.

The design and development of paper-based electrochemical coupled-gated devices for biomolecule detection.

Prof. Dr. Sungbo Cho
Guest Editor

Manuscript Submission Information

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Keywords

  • advanced nanostructured materials
  • foods
  • drug delivery
  • environment
  • disease
  • biosensing
  • DNA nanotechnology
  • real-time monitoring
  • smart electrochemical devices
  • miniaturized devices
  • paper-based electrochemical sensors

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Review

33 pages, 3693 KB  
Review
Nanomaterials-Enhanced Electrochemical Biosensors for Epithelial Cancer Diagnosis: Recent Advances
by Matías Regiart, Alba M. Gimenez, Francisco G. Ortega, Germán E. Gómez, Juan Sainz, Gonzalo R. Tortella and Martín A. Fernández-Baldo
Biosensors 2025, 15(12), 766; https://doi.org/10.3390/bios15120766 - 22 Nov 2025
Cited by 5 | Viewed by 1830
Abstract
In recent years, the interest in electrochemical biosensors has been constantly growing for epithelial cancer diagnosis and prognosis. The incorporation of the different nanomaterials as metal nanoparticles, magnetic nanoparticles, carbon nanomaterials, Metal–Organic Frameworks (MOFs), and nanocomposites, along with specific monoclonal antibodies, and nucleic [...] Read more.
In recent years, the interest in electrochemical biosensors has been constantly growing for epithelial cancer diagnosis and prognosis. The incorporation of the different nanomaterials as metal nanoparticles, magnetic nanoparticles, carbon nanomaterials, Metal–Organic Frameworks (MOFs), and nanocomposites, along with specific monoclonal antibodies, and nucleic acids (aptamers) has improved both sensitivity and specificity in these methodologies. In this review, we have presented examples of electrochemical biosensors for the determination of different epithelial cancer biomarkers. Based on numerous reports in the recent literature, we highlight the use of single and multiplexed analytical platforms for the quantification of epithelial cancer biomarkers. In addition, we outline potential development pathways, current challenges, and future prospects in the field of electrochemical immuno-, apta-, and genosensors. Full article
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