Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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State-of-the-Art Protein X-ray Crystallography
edited by Wu-Pei Su and
submission deadline 31 Jul 2024 | Viewed by 147 | Submission Open
Keywords: ab initio phasing methods; X-ray crystallography; protein structural determination; image reconstruction from Fourier amplitudes; iterative projection algorithms; phasing with deep learning methods
(This special issue belongs to the Section Molecular Structure and Dynamics)
Proteomics in Cancer: Current Research and Future Outlook
edited by Cinzia Franchin
submission deadline 31 Jul 2024 | Viewed by 133 | Submission Open
(This special issue belongs to the Section Biomacromolecules: Proteins)
The Role of Oxidative Stress in Ovarian Cancer submission deadline 31 Jul 2024 | Viewed by 125 | Submission Open
Keywords: ovarian cancer; reactive oxygen species (ROS); metastasis; antioxidant; oxidative stress; chemotherapeutic resistance; inflammation
(This special issue belongs to the Section Molecular Medicine)
Advances in Cancer and Glycosylation
edited by
submission deadline 31 Jul 2024 | Viewed by 119 | Submission Open
Keywords: glycosylation; glycobiology; N-glycans; O-glycans; glycosyltransferases; glycosidases
(This special issue belongs to the Section Molecular Medicine)
Melanin-Related Biomolecules: Synthesis, Properties and Applications
edited by Kazumasa Wakamatsu and
submission deadline 31 Jul 2024 | Viewed by 115 | Submission Open
Keywords: melanin; skin aging; hair color; photoaging; antioxidant action; UV protection; cosmetology; display technology; food industry
(This special issue belongs to the Section Molecular Biology)
Role of the Immune System in Mycobacterial Infection
edited by Auriol Purdie
submission deadline 31 Jul 2024 | Viewed by 104 | Submission Open
Keywords: mycobacterial infections; host immune response; livestock species; zoonotic transmission; cross-species dynamics; macrophages; dendritic cells; T lymphocytes; pro-inflammatory signals; anti-inflammatory signals; immunomodulation; host genetic factors; veterinary immunology; animal health; tuberculosis in livestock; Johne’ s disease (Mycobacterium avium subsp. paratuberculosis); bovine tuberculosis (Mycobacterium bovis); avian tuberculosis (Mycobacterium avium); immune evasion mechanisms; comparative immunology; innate immunity; adaptive immunity; one health approach
Neurocognitive Disorders: From Molecular Mechanisms to Therapeutic Strategies
edited by Mbemba Jabbi
submission deadline 31 Jul 2024 | Viewed by 86 | Submission Open
Keywords: neurocognition; molecular mechanisms; brain anatomy; disease
(This special issue belongs to the Section Molecular Medicine)
Role of the ABI1 Gene in Cancers
edited by Leszek Kotula
submission deadline 31 Jul 2024 | Viewed by 66 | Submission Open
Keywords: ABI1 cancer EMT cell signaling actin cytoskeleton 
(This special issue belongs to the Section Molecular Genetics)
Molecular Mechanisms and Biomedical Applications of Virus Entry
edited by
submission deadline 31 Jul 2024 | Viewed by 61 | Submission Open
Keywords: heparan sulfate; virus entry; virus– host cell interactions; virus cell-to-cell fusion
Molecular Mechanisms of Drug Resistance in Breast Cancer
edited by
submission deadline 1 Aug 2024 | Viewed by 140 | Submission Open
Keywords: breast cancer; mechanism of resistance; targeted therapy resistance; ER+; HER2; TNBC; tumor microenvironment; recurrence; metastasis; tumor evasion
(This special issue belongs to the Section Molecular Medicine)
DNA Methylation in Human Diseases submission deadline 15 Aug 2024 | 2 articles | Viewed by 3878 | Submission Open
Keywords: DNA methylation alterations; DNA methylation profiling; DNMT aberrations; TET aberrations; DNA methylation machinery; DNA methylation biomarkers; DNA methylation reprogramming
(This special issue belongs to the Section Biomacromolecules: Nucleic Acids)
Extracellular Vesicles as Biomarkers of Diseases submission deadline 15 Aug 2024 | 3 articles | Viewed by 3837 | Submission Open
Keywords: extracellular vesicles; metabolic syndrome; cancer; cardiovascular diseases; neurodegenerative diseases; biomarkers
(This special issue belongs to the Section Molecular Biomarkers)
What Is the Weight of Epigenetic Inheritance over Generations? submission deadline 15 Aug 2024 | 2 articles | Viewed by 3134 | Submission Open
Keywords: genetic; epigenetic; transcripts variation; diseases; model organisms
(This special issue belongs to the Section Molecular Genetics)
The Role of Metals Ions in Neurodegenerative Diseases
edited by Imre Sòvágó
submission deadline 15 Aug 2024 | Viewed by 156 | Submission Open
Keywords: Alzheimer’ s disease; Parkinson’ s disease; metal complexes; amyloid-beta; peptide fragments of prion and tau proteins
The Role of Scaffold Proteins in Human Diseases
edited by László Buday and
submission deadline 15 Aug 2024 | Viewed by 81 | Submission Open
Keywords: scaffold proteins; cellular signalling; protein– protein interactions; protein domains; human diseases; drug targets; protein complex formation; pathogenic alterations
Advances in Melanoma Targeted Therapy
edited by
submission deadline 20 Aug 2024 | 2 articles | Viewed by 4002 | Submission Open
Keywords: melanoma; drug discovery; new targets; target discovery
(This special issue belongs to the Section Molecular Medicine)
Advances in the Molecular Mechanisms of Inflammatory Arthritis and Inflammation-Related Bone Changes submission deadline 20 Aug 2024 | 2 articles | Viewed by 2442 | Submission Open
Keywords: inflammatory arthritis; molecular mechanisms; bone changes; osteoimmunology; autoimmunity
(This special issue belongs to the Section Molecular Medicine)
Tryptophan-Kynurenine Pathway in Health and Disease submission deadline 20 Aug 2024 | Viewed by 213 | Submission Open
Keywords: tryptophan; kynurenine pathway; kynurenic acid; neuropsychiatric disorders; metabolic disorders
(This special issue belongs to the Section Molecular Medicine)
Biotechnological and Biomedical Applications of Enzymes Involved in the Synthesis of Nucleosides and Nucleotides—Volume II submission deadline 20 Aug 2024 | Viewed by 75 | Submission Open
Keywords: biotransformations; biomedicine; enzyme technology; biochemistry; organic chemistry
(This special issue belongs to the Section Enzymology)
Role of Thiols in Oxidant-Induced Injuries
edited by
submission deadline 25 Aug 2024 | Viewed by 190 | Submission Open
Keywords: cysteine; sulfhydryl; thiol; antioxidants; reactive oxygen species; free radicals; oxidant-induced injuries
(This special issue belongs to the Section Molecular Biology)
Wnt Pathway Regulation in Development, Stem Cells and Cancer
edited by Marc De La Roche
submission deadline 25 Aug 2024 | Viewed by 171 | Submission Open
Keywords: Wnt pathway regulation and function; metazoan development; stem cells; Wnt pathway driven cancer
(This special issue belongs to the Section Biological Factors)
The Role of Microglia in Aging and Neurodegenerative Disease
edited by
submission deadline 25 Aug 2024 | Viewed by 163 | Submission Open
Keywords: microglia; neurodegenerative diseases; disease-associated  microglia (DAM); microglia activation; Alzheimer's disease; Parkinson’ s disease; ischemic stroke
(This special issue belongs to the Section Molecular Medicine)
Plant Polyphenols in the Immune and Inflammatory Responses - Volume II
edited by
submission deadline 25 Aug 2024 | Viewed by 157 | Submission Open
Keywords: plant polyphenol; bioactivity; immunity; inflammation; molecular mechanism; structure-function relationship
(This special issue belongs to the Section Natural and Bio-inspired Molecules)
Connexins, Pannexins, and Homologous Channel-Forming Proteins submission deadline 30 Aug 2024 | 2 articles | Viewed by 2962 | Submission Open
Keywords: gap junctions; hemichannels; connexins; pannexins; innexins; unnexins; paracrine; autocrine
(This special issue belongs to the Section Biomacromolecules: Proteins)
Non-coding RNAs in Human Diseases: Roles and Mechanisms of Action
edited by Lei Jin
submission deadline 30 Aug 2024 | Viewed by 231 | Submission Open
Keywords: non-coding RNAs; human diseases; diagnostic markers; therapeutic targets; prognostic indicators
(This special issue belongs to the Section Molecular Genetics)
Advances in Neuroproteomics submission deadline 31 Aug 2024 | 5 articles | Viewed by 8510 | Submission Open
Keywords: discovery mass spectrometry; neuroproteomics; mass spectrometry; quantitative proteomics; targeted mass spectrometry
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Mitochondrial Quality Control in Aging and Neurodegeneration
edited by Sofie Lautrup
submission deadline 31 Aug 2024 | 4 articles | Viewed by 8001 | Submission Open
Keywords: mitochondria; quality control; mitochondrial biogenesis; mitochondrial dynamics; fission; fusion; mitophagy; mitochondrial degradation; cellular metabolism; aging; neurodegeneration; neurodegenerative diseases; Alzheimer’ s disease; Parkinson’ s disease
(This special issue belongs to the Section Cellular Biochemistry)
Synuclein Proteins II submission deadline 31 Aug 2024 | 4 articles | Viewed by 7363 | Submission Open
Keywords: synuclein native structures & functions; synuclein genetics; tissue expression and regulation of synucleins; synuclein aggregates; animal models of synucleinopathies; synuclein interacting partners; synuclein and neurotransmission; synuclein and neurodegeneration; synuclein and immune responses
(This special issue belongs to the Section Molecular Biology)
Hormonal Control of Plant Growth and Development
edited by
submission deadline 31 Aug 2024 | 2 articles | Viewed by 2550 | Submission Open
Keywords: plant hormones; auxins; cytokinin; gibberellins; ethylene; abscisic acid; jasmonic acid; salicylic acid; peptide hormones; growth and development
(This special issue belongs to the Section Biological Factors)
Advances in Metabolites Produced by Microbiota submission deadline 31 Aug 2024 | 2 articles | Viewed by 2012 | Submission Open
Keywords: microbiota; metabolites; short-chain fatty acids; amino acids; vitamins
(This special issue belongs to the Section Cellular Biochemistry)
Advances in the Pathology of Prostate Cancer
edited by
submission deadline 31 Aug 2024 | 1 articles | Viewed by 1712 | Submission Open
Keywords: prostate cancer; molecular pathology; biomarker; chemoprevention; therapy
(This special issue belongs to the Section Molecular Biology)
Current Advances in ABC Transporters in Physiology and Disease
edited by
submission deadline 31 Aug 2024 | 1 articles | Viewed by 1592 | Submission Open
Keywords: functions; structure; regulation; genetic polymorphisms
(This special issue belongs to the Section Molecular Biology)
The Illumination of Biophysical Mechanisms by Hydrogen Exchange: A Themed Issue in Honor of Professor S. Walter Englander
edited by
submission deadline 31 Aug 2024 | 1 articles | Viewed by 1530 | Submission Open
Keywords: hydrogen exchange chemistry; HX– NMR; HX-MS; protein folding; allostery; protein binding; protein thermodynamics; protein biophysics; protein function
The Role of P-type ATPases in Health and Diseases submission deadline 31 Aug 2024 | 1 articles | Viewed by 1351 | Submission Open
Keywords: P-type ATPases; Na; K-ATPase; H-ATPase; H; K-ATPase; Ca-ATPase; Cu-ATPase; phospholipid flippases; genetic disease
(This special issue belongs to the Section Cellular Biochemistry)
Key Molecules in Traditional Medicine: From Molecular Mechanisms to Therapies Strategies
edited by and
submission deadline 31 Aug 2024 | 1 articles | Viewed by 873 | Submission Open
Keywords: natural compounds; traditional medicine; biomolecules in medicinal herbs; molecular changes caused by traditional medicine treatments
(This special issue belongs to the Section Natural and Bio-inspired Molecules)
New Insight into the Molecular Genetics of Neurodevelopmental Disorders
edited by and Flavio Faletra
submission deadline 31 Aug 2024 | Viewed by 406 | Submission Open
Keywords: neurodevelopmental disorders; next generation sequencing; pathomechanisms; phenotypic spectra; phenotype-genotype correlation
(This special issue belongs to the Section Molecular Genetics)
The Central Role of Mitochondrial Protein VDAC1 in Human Diseases – Honorary Special Issue Commemorating the Work of Prof. Varda Shoshan-Barmatz
edited by Jay H. Chung
submission deadline 31 Aug 2024 | Viewed by 292 | Submission Open
Keywords: apoptosis; ferroptosis; inflammation; metabolism; mitochondria; oxidative stress; pyroptosis; VDAC; cancer
(This special issue belongs to the Section Cellular Biochemistry)
Two Billion Years of Sex submission deadline 31 Aug 2024 | Viewed by 250 | Submission Open
Keywords: sex chromosomes; sex determination; separate sexes; mating types; XY; ZW
(This special issue belongs to the Section Molecular Biology)
Properties and Functions of Endometrial Stromal Cells submission deadline 31 Aug 2024 | Viewed by 127 | Submission Open
Keywords: endometrium; endometriosis; molecular reproduction; implantation; decidualization; placentation; inflammation; reproductive endocrinology; assisted reproductive technology; molecular reproductive biology
(This special issue belongs to the Section Cellular Biochemistry)
Molecular Biomarkers in Cardiology 2024
edited by
submission deadline 31 Aug 2024 | Viewed by 101 | Submission Open
Keywords: cardiovascular diseases; cardiovascular pathology and histology; carotid plaques and histology; endothelium and endothelial dysfunction; veins diseases; arrhythmias; heart
Cannabinoids in Neurobehavioral Modulation submission deadline 31 Aug 2024 | Viewed by 92 | Submission Open
Keywords: cannabinoids; neurobehavior; brain diseases; therapeutic; translational
(This special issue belongs to the Section Chemical Biology)
Harnessing Protein Design and Engineering for Therapeutic Applications
edited by Julia Shifman and Norman Metanis
submission deadline 31 Aug 2024 | Viewed by 87 | Submission Open
Keywords: therapeutic peptides and proteins; protein design and engineering; chemical protein synthesis; chemoselective protein modification; posttranslational protein modification
(This special issue belongs to the Section Molecular Structure and Dynamics)
Biosynthesis and Function of Thyroid Hormones
edited by and Eva K. Wirth
submission deadline 31 Aug 2024 | Viewed by 76 | Submission Open
Keywords: thyroid gland; thyroid follicle; TH release; iodide; deiodinase; TH transmembrane transport; TH receptors; intracellular TH binding proteins; thyroglobulin; sodium– iodide symporter; thyroperoxidase; dual oxidase; thyroid-relevant trace elements
(This special issue belongs to the Section Biological Factors)
Next-Generation Nutraceuticals: Unlocking New Pathways for Cellular Health beyond the Foods submission deadline 31 Aug 2024 | Viewed by 72 | Submission Open
Keywords: nutraceuticals; cellular health; cellular aging mechanisms; chronic diseases; immune balance
Recent Advances in Adduct Science
edited by Yukari Totsuka and Haruhiko Sugimura
submission deadline 31 Aug 2024 | Viewed by 48 | Submission Open
Keywords: adductomics; protein- or nucleic acid-adducts; biomarkers; exposome; genomic mutations; disease etiology; preventive strategies; drug discovery; risk assessment
Lymphangiogenesis in Health and Disease
edited by Rui-Cheng Ji
submission deadline 10 Sep 2024 | Viewed by 251 | Submission Open
Keywords: lymphatic endothelial cells; lymphatic vessels; lymphangiogenic molecules
(This special issue belongs to the Section Molecular Medicine)
Host Molecules and Molecular Mechanisms in Insects and Crustaceans submission deadline 10 Sep 2024 | Viewed by 149 | Submission Open
Keywords: insects; crustaceans; disease control and management; evolutionary biology; environmental monitoring and conservation
Molecular Plant Reproduction: From Cells to Nature
edited by
submission deadline 15 Sep 2024 | 6 articles | Viewed by 10652 | Submission Open
Keywords: botany; cell-to-cell communication; embryo development; endosperm development; floral development; gametogenesis; genome editing; genomics; metabolomics; meiosis; plant– environment interactions; transcriptomics
(This special issue belongs to the Section Molecular Reproduction)
Molecular Mechanism Investigations into Membrane Fusion
edited by James McNew
submission deadline 15 Sep 2024 | 5 articles | Viewed by 7570 | Submission Open
(This special issue belongs to the Section Cellular Biochemistry)
Cancer Immunotherapy and the PD-1/PD-L1 Checkpoint Pathway submission deadline 15 Sep 2024 | 3 articles | Viewed by 3685 | Submission Open
Keywords: immunotherapy; biomarkers; PD-1/PD-L1
(This special issue belongs to the Section Molecular Biology)
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