Endocrine Regulation of Reproductive Tissues: From Molecular Mechanisms to Therapies
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Biological Factors".
Deadline for manuscript submissions: 25 February 2026 | Viewed by 44
Special Issue Editor
Special Issue Information
Dear Colleagues,
Reproduction in animals is intricately regulated by endocrine signaling, which governs the development, function, and homeostasis of reproductive tissues. Hormones and their receptors coordinate essential processes such as gametogenesis, steroidogenesis, and reproductive cyclicity across diverse species. While balanced endocrine activity ensures fertility and reproductive success, disruptions due to genetic, epigenetic, or environmental factors can lead to disorders like infertility, endometriosis, and hormone-dependent cancers. Despite advances in understanding hormone-receptor interactions, the integration of systemic endocrine signals with tissue-specific mechanisms remains incompletely understood, particularly in non-model organisms.
This Special Issue invites contributions exploring endocrine regulation in reproductive biology, from molecular mechanisms to therapeutic applications. We welcome studies on hormonal cross-talk with intracellular signaling, epigenetic modifiers, and the impact of endocrine disruptors on reproductive health. Submissions may include research on novel diagnostics, hormone-based therapies, and innovative strategies to address reproductive dysfunction in both humans and animals.
Dr. Waldemar Grzegorzewski
Guest Editor
Manuscript Submission Information
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Keywords
- hormone signaling
- reproductive physiology
- steroid receptors
- infertility
- endocrine disruptors
- epigenetic regulation
- gonadal steroids
- hormone-dependent cancers
- therapeutic targeting
- gametogenesis
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