Cellular Signaling and Cardiovascular Diseases: From NF-κB to Golgi Dynamics
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Cellular Biochemistry".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 57
Special Issue Editor
Special Issue Information
Dear Colleagues,
Cardiovascular diseases (CVDs) are a leading cause of morbidity and mortality worldwide and are driven by multifaceted cellular and molecular mechanisms. Vascular cells, particularly endothelial cells (ECs) and vascular smooth muscle cells (VSMCs), play central roles in maintaining vascular integrity and function. The dysregulation of signaling pathways in these cells contributes to inflammation, immune activation, and pathological remodeling characteristics in many CVDs. Among these pathways, NF-κB signaling has been extensively studied for its role in promoting vascular inflammation and immune responses. In parallel, epigenetic regulation and emerging insights into subcellular organelle dynamics—such as Golgi apparatus remodeling—have opened up new avenues for understanding the progression of cardiovascular pathology.
For this Special Issue of Biomolecules, “Cellular Signaling and Cardiovascular Diseases: From NF-κB to Golgi Dynamics”, we invite original research and review articles focusing on the molecular signaling mechanisms that drive CVDs. Topics of interest include NF-κB signaling, EC and VSMC biology, inflammation, immunity, epigenetic mechanisms, cell migration, and the roles of organelles in signal transduction. Submissions that incorporate molecular, cellular, and translational approaches are particularly encouraged.
We look forward to receiving your valuable contributions.
Dr. Tong-You Wei
Guest Editor
Manuscript Submission Information
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Keywords
- cardiovascular diseases
- NF-κB signaling
- vascular cells
- epigenetic regulation
- vascular inflammation
- intercellular crosstalk
- Golgi dynamics
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