Exploring the Pathophysiology of Epilepsy: Metabolic Mechanisms and Therapeutic Potential
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 35
Special Issue Editors
2. Neurophysiology Unit, Department of Biomedical Sciences, University of Veterinary Medicine Vienna, 1210 Vienna, Austria
3. Institute of Biochemical Pharmacology, University of Vienna, Borschkegasse 8, 1090 Vienna, Austria
Interests: tryptophan metabolism; epilepsy; neurodegenerative diseases; Alzheimer’s disease
2. Karl Landsteiner Institute for Clinical Epilepsy Research and Cognitive Neurology, Wolkersbergenstrasse 1, 1090 Vienna, Austria
3. Medical Faculty, Sigmund Freud University, Freudplatz 3, 1020 Vienna, Austria
Interests: epilepsy; Alzheimer’s disease; Parkinson; stroke
Special Issue Information
Dear Colleagues,
Epilepsy is a complex neurological disorder characterized by recurrent, unprovoked seizures resulting from abnormal, synchronous neuronal activity in the brain. It is often accompanied by cognitive, psychological, and social comorbidities that significantly impair quality of life. This Special Issue aims to compile high-quality original research, reviews, and short communications, with a focus on the molecular mechanisms and signaling pathways of metabolic regulation in epilepsy, as well as the application of metabolism in epilepsy pathology, detection methods, and innovative therapies. By focusing on cutting-edge discoveries and insights, this Special Issue seeks to bridge basic science with practical applications, offering valuable perspectives for researchers and clinicians dedicated to improving the health outcomes of epilepsy patients.
Topics for this Special Issue include, but are not limited to, the following:
- Behavioral, biochemical, and pharmacological studies in the kainic acid animal model for human temporal lobe epilepsy;
- Enzymology, neurodegeneration, and neuroprotection;
- Neuromodulators, neurotransmitters, and amino acids;
- Kynurenine metabolism in the central and peripheral nervous systems of humans and animals.
Prof. Dr. Halina Baran
Prof. Dr. Christoph Baumgartner
Guest Editors
Manuscript Submission Information
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Keywords
- epilepsy
- metabolic regulation
- signaling pathways
- kynurenic acid
- seizure detection
- antiseizure drugs
- innovative therapies
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