Polyphosphate (PolyP) in Health and Disease
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Natural and Bio-derived Molecules".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 346
Special Issue Editor
Interests: polyphosphate; polyP; polymer; phosphate
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Inorganic polyphosphate (polyP), a linear polymer of orthophosphate residues, is a ubiquitous molecule with increasingly recognized roles in health and disease. Recent discoveries of the implications of polyP in physiological and pathological processes such as bioenergetics, inflammation, neurodegeneration, cardiovascular disorders, and cancer, among others, are currently being explored, so there is a need to improve and accelerate the dissemination of this new knowledge. As novel methodologies progress in our ability to detect, manipulate, and quantify polyP, new insights into its functions are being uncovered. However, this field still has significant knowledge gaps, particularly concerning the interplay between polyP molecular roles and disease pathophysiology. This Special Issue of Biomolecules aims to highlight recent advances in polyP research, focusing on its functions, physiological relevance, and contribution to disease mechanisms. Original research articles, methodological advances, and comprehensive reviews that expand our understanding of polyP biology and its potential as a biomarker or therapeutic target in various clinical contexts are welcome.
Dr. Félix A. Ruiz
Guest Editor
Manuscript Submission Information
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Keywords
- polyphosphate
- polyP
- biomarker and therapeutic target
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