Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Hepatology
edited by Yuanwen Chen
submission deadline 31 Dec 2025 | 5 articles | Viewed by 4473 | Submission Open
Keywords: metabolic dysfunction-associated steatotic liver disease (MASLD); metabolic dysfunction-associated steatohepatitis (MASH); alcohol-associated liver disease (ALD); alcohol-associated hepatitis; viral hepatitis; liver cancer; autoimmune liver diseases; liver fibrosis; gut microbiota; neuroimmune; inflammatory mechanisms; oxidative stress; reversibly oxidized human non-mercaptalbumin-1; irreversibly oxidized human non-mercaptalbumin-2 (HNA2)
(This special issue belongs to the Section Molecular and Translational Medicine)
Neurotransmitters in Health and Diseases
edited by and Krisztina Csabafi
submission deadline 31 Dec 2025 | 3 articles | Viewed by 4257 | Submission Open
Keywords: neurotransmitters; GABA; dopamine; glutamate; acetylcholine; neurohormones; neuromodulators
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Molecular Research in Breast Cancer submission deadline 31 Dec 2025 | 2 articles | Viewed by 4085 | Submission Open
Keywords: breast cancer; apoptosis; signaling pathways; drug resistance; metastasis; cancer stem cells; microRNA; biomarkers; drug target; tumor metabolism; tumor immunity
(This special issue belongs to the Section Molecular and Translational Medicine)
Nano-Based Drug Delivery and Drug Discovery
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 3964 | Submission Open
Keywords: nanotechnology; drug discovery; drug delivery; nanocarriers; nanomaterials; drug targeting; drug release; drug therapeutic
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Antioxidant Materials with Additional Biological Properties
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 3206 | Submission Open
Keywords: natural antioxidants; flavonoids; and polyphenols; biocompatible and blood compatible; hydrogel; microgels; nanogel; and particles; polymeric particles; carbon quantum dots; and g-C3N4; stimuli-responsive materials; drug delivery systems; controlled release; and targeted delivery/therapies; antibacterial; antifungal; antiviral; anticancer; and biocidal; ROS-scavenging activity; proteins; enzyme; peptides; and amino acids; activate-able materials and photodynamic therapy
(This special issue belongs to the Section Biomedical Engineering and Materials)
New Insights in Hematologic Malignancies: From Pathophysiologic Mechanisms to Therapeutic Strategies
edited by
submission deadline 31 Dec 2025 | 4 articles | Viewed by 3188 | Submission Open
Keywords: leukemia; hematological malignancies; tumor microenvironment; disease models; precision medicine; immunotherapy; targeted therapy; drug resistance; biomarkers; translational research
(This special issue belongs to the Section Cancer Biology and Oncology)
From Molecules to Minds: Translational Breakthroughs in Preclinical Psychiatry submission deadline 31 Dec 2025 | 1 articles | Viewed by 2569 | Submission Open
Keywords: depression; anxiety; bipolar disorder; post-traumatic stress disorder; mental disorders; epigenomics; psychiatric disorders/genetics; circadian rhythm; sex characteristics; mitochondrial dysfunction; neurotoxins; intergenerational transmission; cannabinoid receptor modulators; adolescent neuroplasticity; synaptic pruning; psychoimmunology; preclinical studies; translational medical research; neuroplasticity; neuromodulation; phytochemicals; plant extracts; transcranial magnetic stimulation
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced Research on Psychiatric Disorders
edited by Wen Zhang
submission deadline 31 Dec 2025 | 1 articles | Viewed by 2541 | Submission Open
Keywords: psychiatric disorders; artificial intelligence; predictive modeling; personalized treatment strategies; animal experiments; risk factors; multimodal approaches
(This special issue belongs to the Section Molecular and Translational Medicine)
New Insights in Respiratory Diseases
edited by
submission deadline 31 Dec 2025 | 5 articles | Viewed by 2519 | Submission Open
Keywords: asthma; COPD; bronchiectasis; genetic; therapeutics
(This special issue belongs to the Section Molecular and Translational Medicine)
Liver Disease: Etiology, Pathology, and Treatment
edited by Ivana Mikolašević
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1790 | Submission Open
Keywords: chronic liver disease; metabolic-associated fatty liver disease; liver fibrosis; liver injury; etiology; pathology; molecular and cellular mechanisms; biomarkers and therapeutic targets; immunotherapy; prevention and treatment
(This special issue belongs to the Section Cell Biology and Pathology)
Recent Therapeutic Advances in Parkinson’s Disease
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1560 | Submission Open
Keywords: Parkinson's disease; disease-modifying therapy; continuous dopaminergic stimulation; non-dopaminergic drugs; deep brain stimulation; drug repurposing; immunotherapies; gene therapies
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advances in Reproductive Medicine and Health
edited by Athanasios Zikopoulos, Sofoklis Stavros and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1558 | Submission Open
Keywords: reproductive medicine; assisted reproductive technology; fertility preservation; IVF; early pregnancy; miscarriages; proteomics; metabolomics; transcriptomics; infertility; bioethics; cryopreservation; personalized medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Oxidative Stress in Health and Disease
edited by Federica Mannino
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1514 | Submission Open
Keywords: oxidative stress; inflammation; human diseases; apoptosis; peroxidation; DNA damage; mitochondria
(This special issue belongs to the Section Cell Biology and Pathology)
State-of-the-Art Molecular and Translational Medicine in USA submission deadline 31 Dec 2025 | 1 articles | Viewed by 1496 | Submission Open
Keywords: diagnostics; therapeutics; prevention; cellular biology; disease mechanisms; precision medicine; biomarker discovery; immunotherapies; bioinformatics
(This special issue belongs to the Section Molecular and Translational Medicine)
Genetic and Molecular Mechanisms of Cardiometabolic Diseases and Cancers—2nd Edition
edited by Tao Wu and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1305 | Submission Open
Keywords: cardiometabolic disease; oncology; comorbidity; genetic pleiotropy; direct genetic effects; indirect genetic effects; parent-of-origin
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
The Gut Microbiome in Early Life and Beyond: Implications for Health and Disease
edited by and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1286 | Submission Open
Keywords: gut microbiome; early-life development; DOHaD; microbial dysbiosis; chronic disease; probiotics; prebiotics; microbiome– host interactions; developmental programming; translational research
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Glomerular Disease and Cystic Kidney Disease: From Pathogenesis to Novel Therapeutic Approaches—2nd Edition
edited by Vassilis Filiopoulos and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1262 | Submission Open
Keywords: glomerular disease; glomerulonephritis; glomerulopathy; podocytopathies; ciliopathies; cystic kidney disease; polycystic kidney disease; tolvaptan; vasopressin
(This special issue belongs to the Section Molecular and Translational Medicine)
Zebrafish Models for Development and Disease—5th Edition
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1223 | Submission Open
Keywords: disease model; drug screening model; teratogen screening; toxicological screening; neuroscience; behavior; developmental biology
(This special issue belongs to the Section Molecular and Translational Medicine)
Navigating the Complex Landscape of Non-Communicable Respiratory Diseases: Emerging Challenges and Opportunities
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1140 | Submission Open
Keywords: non-communicable respiratory diseases; asthma; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease
(This special issue belongs to the Section Molecular and Translational Medicine)
Pathophysiology of Fatty Acid Metabolism submission deadline 31 Dec 2025 | 1 articles | Viewed by 1096 | Submission Open
Keywords: fatty acids; signalling molecules; gene expression; metabolic disorders
(This special issue belongs to the Section Endocrinology and Metabolism Research)
The Role of Telomere and Telomerase in Human Disease—2nd Edition
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1014 | Submission Open
Keywords: telomere; telomerase; cancer; aging
(This special issue belongs to the Section Molecular and Translational Medicine)
Current Trends in Regenerative Medicine submission deadline 31 Dec 2025 | Viewed by 978 | Submission Open
Keywords: regenerative medicine; stem cells; organoids; tissue engineering; gene therapy; cell therapy; biomaterials; personalized medicine
(This special issue belongs to the Section Gene and Cell Therapy)
Recent Advances in Gastrointestinal Cancers: From Microbiota Modulation to New Therapeutic Approaches—2nd Edition
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 925 | Submission Open
Keywords: gastrointestinal cancers; microbiota; anticancer therapy; immunotherapy; precision medicine
(This special issue belongs to the Section Cancer Biology and Oncology)
Advanced Research on Diabetic Retinopathy
edited by Stamatios Lampsas
submission deadline 31 Dec 2025 | 1 articles | Viewed by 762 | Submission Open
Keywords: diebetic retinopathy; retinal diseases; novel treatment strategies; progression; pathogenetic mechanisms; non-proliferative diabetic retinopathy; proliferative diabetic retinopathy
(This special issue belongs to the Section Molecular and Translational Medicine)
Chronic Heart Failure: From Biomarkers to Targeted Therapies
edited by
submission deadline 31 Dec 2025 | Viewed by 755 | Submission Open
Keywords: biomarkers in heart failure; GDMT in heart failure; targeted therapies
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Current Perspectives on Gynecologic Cancers
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 754 | Submission Open
Keywords: gynecology; genetics; biology; bioinformatics; review; predictive model; artificial intelligence
(This special issue belongs to the Section Cancer Biology and Oncology)
New Challenges in the Study of Liver Diseases: From Molecular Pathogenesis to Therapeutic Approaches—4th Edition
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 722 | Submission Open
Keywords: liver diseases and related pathologies; non-alcoholic fatty liver diseases (NAFLDs); obesity; type 2 diabetes; cardiovascular diseases; gut– liver axis; viral hepatitis; alcoholic liver diseases (ALDs); cholestatic disorders; personalized medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Genomics of Oral Submucous Fibrosis Pathology
edited by Sanjit Mukherjee
submission deadline 31 Dec 2025 | Viewed by 687 | Submission Open
Keywords: oral submucous fibrosis; gene expression; biomarker; DNA methylation; epigenetic drugs; immune biomarkers; pathology; therapeutic interventions; epithelial mesenchymal transition; cancer stem cell marker
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Precision Oncology for Thyroid Carcinoma: Integrating Artificial Intelligence, Genomics and Molecular Diagnostics
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 676 | Submission Open
Keywords: thyroid carcinoma; artificial intelligence; genomics; precision oncology; molecular diagnostics
(This special issue belongs to the Section Cancer Biology and Oncology)
Feature Reviews on Diabetes Pathophysiology and Treatment
edited by
submission deadline 31 Dec 2025 | Viewed by 577 | Submission Open
Keywords: type 1 diabetes mellitus; type 2 diabetes mellitus; pathophysiology; treatment; self-management; technology; continuous glucose monitoring; pump therapy; digital applications
(This special issue belongs to the Section Molecular and Translational Medicine)
Liver Fibrosis: Molecular Mechanisms, Potential Therapeutic Targets and Clinical Biomarkers, 2nd Edition
edited by
submission deadline 31 Dec 2025 | Viewed by 504 | Submission Open
Keywords: liver fibrosis treatment; therapeutic target biomarker; hepatitis; NAFLD; NASH; MAFLD; HSC; GPCR; immunity cell death
(This special issue belongs to the Section Molecular and Translational Medicine)
CDK Inhibitors: A New Wave of Therapeutic Agents for Human Diseases
edited by Mengqian Chen
submission deadline 31 Dec 2025 | Viewed by 455 | Submission Open
Keywords: cyclin-dependent kinases (CDKs); cell-cycle CDKs; transcriptional CDKs; CDK inhibitors; CDK degraders; cancer therapeutics; inflammatory diseases; neurodegenerative disorders; pharmacology; clinical trials
(This special issue belongs to the Section Cancer Biology and Oncology)
Neglected Infectious Diseases: From Pathophysiology to Therapy
edited by Raimunda Nonata Ribeiro Sampaio
submission deadline 31 Dec 2025 | Viewed by 431 | Submission Open
Keywords: pathophysiology; host– parasite infection interactions; diagnostic tools; therapeutic intervention; novel biomarkers
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Diagnosis, Pathogenesis and Treatment of CNS Tumors (2nd Edition)
edited by
submission deadline 31 Dec 2025 | Viewed by 414 | Submission Open
Keywords: CNS tumors; diagnosis; pathogenesis; treatment; prognosis; molecular markers
(This special issue belongs to the Section Molecular and Translational Medicine)
State-of-the-Art Neurobiology and Clinical Neuroscience in the United States
edited by and
submission deadline 31 Dec 2025 | Viewed by 414 | Submission Open
Keywords: neurobiology; neuroscience; bioinformatics; Alzheimer’ s disease; Parkinson’ s disease; imaging; neurotransmitters; neurodegeneration; clinical; population genetics
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Nanomedicine Applications in the Diagnosis and Treatment of Neurodegenerative Diseases
edited by
submission deadline 31 Dec 2025 | Viewed by 379 | Submission Open
Keywords: neurodegenerative diseases; nanomedicine; blood– brain barrier permeability; early diagnosis and treatment; biosensing and bioimaging
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Neuromuscular Diseases: From Pathophysiology to Novel Therapeutic Approaches
edited by Marco A.F. Fernandes
submission deadline 31 Dec 2025 | Viewed by 365 | Submission Open
Keywords: neuromuscular diseases; amyotrophic lateral sclerosis (ALS); muscular dystrophy; myasthenia gravis; neuromyotonia; peripheral neuropathy; pathophysiology; gene therapy; targeted drugs; regenerative medicine
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Fetal Medicine: New Insights and Future Direction submission deadline 31 Dec 2025 | Viewed by 285 | Submission Open
Keywords: fetal medicine; fetal therapy; prenatal screening; congenital defects; high-risk pregnancy
(This special issue belongs to the Section Molecular and Translational Medicine)
Unleashing the Power of Innovative Nanoparticles for Enhanced Radiation Therapy
edited by Fangchao Jiang
submission deadline 31 Dec 2025 | Viewed by 277 | Submission Open
Keywords: nanomedicine; drug delivery; radiation therapy; nanotheranostics; nanoparticles; cancer treatment; biomaterial
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Supraventricular and Ventricular Cardiac Arrhythmias Systemic Implications: From Mechanisms to Clinical Treatment submission deadline 31 Dec 2025 | Viewed by 262 | Submission Open
Keywords: cardiac arrhythmias; atrial fibrillation; ventricular tachycardia; AVNRT; PVC; supraventricular tachycardia; catheter ablation; electrophysiological study; heart failure; arrhythmias diagnostic; antiarrhythmic treatment; biomarkers; ion channels; cardiac resynchronization therapy; ICD
(This special issue belongs to the Section Molecular and Translational Medicine)
Breast Cancer Research: Charting Future Directions submission deadline 31 Dec 2025 | 1 articles | Viewed by 232 | Submission Open
Keywords: personalized medicine; biomarkers for early detection; immunotherapy; patient-reported outcomes
(This special issue belongs to the Section Cancer Biology and Oncology)
Molecular Regulation of Cancer Progression and Metastasis to Identify Novel Treatment Strategies
edited by
submission deadline 31 Dec 2025 | Viewed by 227 | Submission Open
Keywords: cancer; cancer progression; cancer treatment; solid tumors; immune response; metastasis; tumor suppressor; oncogene
(This special issue belongs to the Section Cancer Biology and Oncology)
Exploring Neuroinflammation in Central and Peripheral Neuropathic Pain and Related Disorders
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 225 | Submission Open
Keywords: neuroinflammation; neuropathic pain; central nervous system; peripheral nervous system; affective disorders; cognitive disorders; in silico modeling; in vitro assays; in vivo models; medical and non-pharmacological interventions
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Feature Review: Advanced Manufacturing, Biomaterials, and Stem Cells for Tissue and Regenerative Engineering submission deadline 31 Dec 2025 | Viewed by 217 | Submission Open
Keywords: advanced manufacturing; biomaterials; tissue engineering; regenerative medicine
(This special issue belongs to the Section Biomedical Engineering and Materials)
Advances in Wound Healing
edited by and
submission deadline 31 Dec 2025 | Viewed by 198 | Submission Open
Keywords: wound healing; scar and keloid; diabetic ulcers; multi-omics analysis for wound healing; biomaterials for wound healing; tissue engineering for wound healing; wound infection management; clinical trials and cases of wound healing
(This special issue belongs to the Section Molecular and Translational Medicine)
NASH and Hepatocellular Carcinoma (HCC)—2nd Edition
edited by , and Xin Yang
submission deadline 31 Dec 2025 | Viewed by 193 | Submission Open
Keywords: NAFLD; NASH; HCC; obesity; inflammation; immunotherapy; stress
(This special issue belongs to the Section Cancer Biology and Oncology)
Advanced Research in Mitochondrial Medicine and Nanomedicine submission deadline 31 Dec 2025 | Viewed by 188 | Submission Open
Keywords: nanomedicine; nanoparticles; drug delivery; mitochondria; cancer; neurodegenerative disease; metabolism; targeted therapy; mitochondrial function; bioactive compounds
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Mechanism of Mesenchymal Stromal Cells and Their Derivatives in Regenerative Medicine
edited by Jia Xian Law and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 184 | Submission Open
Keywords: mesenchymal stromal cell; regenerative medicine; stem cell; extracellular vesicle; mechanism of action; paracrine factor; secretome; tissue engineering
(This special issue belongs to the Section Biomedical Engineering and Materials)
Advances in Hematological Malignancies: Diagnostic Strategies, Molecular Mechanisms, Prognostic Markers and Therapeutic Approaches
edited by José Antonio García-Vela and Fernando Martin-Moro
submission deadline 31 Dec 2025 | Viewed by 184 | Submission Open
Keywords: hematological malignancies; diagnostic strategies; hematopathology; flow cytometry; molecular biology; prognostic markers; targeted therapies; immunotherapy; cellular therapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Nanoparticle-Based Therapeutic Delivery Systems in Cancer Therapy
edited by
submission deadline 31 Dec 2025 | Viewed by 175 | Submission Open
Keywords: drug delivery; nanomedicine; biomaterials; multimodal drug delivery; tumor microenvironment; immunotherapy; targeted delivery
(This special issue belongs to the Section Cancer Biology and Oncology)
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