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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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MicroRNA and Its Role in Human Health, 2nd Edition

edited by

Shih-Yao Chen

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1905 | Submission Open

Keywords: microRNA; disease models; disease associations; molecular mechanism; molecular diagnosis; molecular therapy

(This special issue belongs to the Section Cell Biology and Pathology)

New Advances in Cardiovascular Drugs: In Memory of Professor Akira Endo

edited by

Alfredo Caturano

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1885 | Submission Open

Keywords: cardiovascular drugs; statins; metformin; SGLT2i; laboratory; drug targets; translational research; targeted therapy

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Emerging Therapeutic Strategies for Epilepsy: Bridging Research and Clinical Practice

edited by Tanveer Singh

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1567 | Submission Open

Keywords: epilepsy; status epilepticus; MRI; EEG; inhibitory neurotransmission; immunohistochemistry; gene regulation; neurodegeneration; precision medicine

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Convergence of Allergology and Immunology: Unveiling Mechanistic Insights

edited by

Kinga Lis

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1454 | Submission Open

Keywords: allergy; hypersensitivity; allergens; immunological mechanisms; immunological diagnostics; immunotherapy

(This special issue belongs to the Section Immunology and Immunotherapy)

Renin-Angiotensin System in Cardiovascular Biology, 2nd Edition

edited by

Mária Szekeres

György L. Nádasy

and

László Dézsi

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1449 | Submission Open

Keywords: renin– angiotensin system (RAS); signaling mechanisms of angiotensin receptors; GPCR; AT1R; AT2R; ACE; ACE2; ACEI; angiotensin II; signal transduction; cardiovascular system; hypertension; atherosclerosis; heart failure; cardiovascular remodeling; osmoregulation; inflammation

(This special issue belongs to the Section Molecular and Translational Medicine)

Advanced Research in Secondary Immunodeficiency in Oncohematological Diseases

edited by

Giuseppe Murdaca

and

Sebastiano Gangemi

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1426 | Submission Open

Keywords: secondary immunodeficiencies and opportunistic infections; secondary immunodeficiencies and B-lymphocytes; secondary immunodeficiencies and hematological diseases; secondary immunodeficiencies and cancers; secondary immunodeficiencies and novel cancer treatments; secondary immunodeficiencies and oxidative stress

(This special issue belongs to the Section Immunology and Immunotherapy)

Protein Misfolding and Functional Impairment in Neurodegenerative Diseases

edited by

Marios Krokidis

Themis Exarchos

and

Panayiotis Vlamos

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1402 | Submission Open

Keywords: protein misfolding; chaperones; energy landscape; neurodegenerative diseases; amyloidogenesis; intrinsically disordered proteins; structure prediction algorithms; bioinformatics; molecular dynamic simulations

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Unraveling New Horizon in Vascular Diseases: From Pathophysiology to Novel Therapeutic

edited by Miguel A. Ortega and

Raul Diaz-Pedrero

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1378 | Submission Open

Keywords: vascular diseases; artery; venous disease; venous hypertension; heart; lymph; diabetes; surgery; immune system; translational medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Microbial Metabolites and Their Impact on Gut Homeostasis

edited by

Federica Laudisi

and

Carmine Stolfi

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1251 | Submission Open

Keywords: intestinal microbiota; microbial metabolites; gut homeostasis; inflammatory response; intestinal epithelial barrier; immune response; diet

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Sex Hormones and Cardiovascular Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by

Renáta Szabó

and

Denise Börzsei

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1187 | Submission Open

Keywords: endogenous sex hormones; aging; sexual dimorphism; hormone replacement therapy; CVDs; hypertension; myocardial infarction; atherosclerosis

(This special issue belongs to the Section Molecular and Translational Medicine)

Prostate Cancer Targeted Therapy: Highlighting Advances in Precision Medicine and Rational Combination Approaches

edited by Alan P. Lombard

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1104 | Submission Open

Keywords: prostate cancer; precision medicine; targeted therapeutics; rational drug combinations; clinical biomarkers

(This special issue belongs to the Section Cancer Biology and Oncology)

Updates on Kawasaki Disease

edited by Eisuke Suganuma

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1034 | Submission Open

Keywords: coronary artery aneurysm; cluster; individualized treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Hepatocellular Carcinoma Pathogenesis and Therapy

edited by Junyan Tao

submission deadline 31 Oct 2025 | 1 articles | Viewed by 996 | Submission Open

Keywords: HCC (hepatocellular carcinoma); early diagnosis; molecular pathology characteristics; molecular target therapy; combination therapy; immune checkpoint inhibitors; precision medicine; HCC heterogeneity; drug resistance; HCC risk factors

(This special issue belongs to the Section Cancer Biology and Oncology)

Allergic Rhinitis: From Pathology to Novel Therapeutic Approaches

edited by

Shaoqing Yu

submission deadline 31 Oct 2025 | 1 articles | Viewed by 881 | Submission Open

Keywords: allergic rhinitis; immunotherapy; immune mechanisms in allergy; rhinitis biomarkers

(This special issue belongs to the Section Immunology and Immunotherapy)

Advances in Heparan Sulfate Biology: Protein Interactions and Therapeutic Implications

edited by Miaomiao Li

submission deadline 31 Oct 2025 | 1 articles | Viewed by 763 | Submission Open

Keywords: heparan sulfate; heparin; heparanase; heparan sulfate-binding protein; heparan sulfate oligosaccharides; antibody; natural sulfated carbohydrates

(This special issue belongs to the Section Cell Biology and Pathology)

Glioma Therapy: Current Status and Future Prospects

edited by Bernd Kaina

submission deadline 31 Oct 2025 | 1 articles | Viewed by 748 | Submission Open

Keywords: glioblastoma; temozolomide; nitrosoureas; immunotherapy; biologicals; tyrosine kinase inhibitors; senotherapeutics

(This special issue belongs to the Section Cancer Biology and Oncology)

Exploitation and Development of “Synthetic Lethality” Strategy for Cancer Therapy

edited by Guo Chen

submission deadline 31 Oct 2025 | Viewed by 644 | Submission Open

Keywords: anti-cancer therpies; PARP inhibitors; synthetic lethality

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Strategies for Anticancer in p53 Mutated Cancers

edited by

Bi-He Cai

and

Ching-Feng Lien

submission deadline 31 Oct 2025 | 1 articles | Viewed by 642 | Submission Open

Keywords: p53; p63; p73; tumor suppressor gene; microRNA; long non-coding RNA; protein degradation; heat shock proteins; mutation; oncology

(This special issue belongs to the Section Cancer Biology and Oncology)

Past, Present and Further Looking for Therapeutic Management of Pancreatic Ductal Adenocarcinoma (2nd Edition)

edited by

Gennaro Nappo

and

Niccola Funel

submission deadline 31 Oct 2025 | 1 articles | Viewed by 572 | Submission Open

Keywords: pancreatic cancer; pancreatic ductal adenocarcinoma; treatment pancreatic cancer; chemotherapy pancreatic cancer; radiotherapy pancreatic cancer; pancreatic cancer biology; PDAC preclinical model; biomolecular markers; theragnostic molecules; target therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Latest Advancements in Radiotherapy

edited by

Moshi Geso

submission deadline 31 Oct 2025 | 1 articles | Viewed by 562 | Submission Open

Keywords: radiobiology; dosimetry; nanoparticles; FLASH; radiation

(This special issue belongs to the Section Molecular and Translational Medicine)

Vitamin D: Latest Scientific Discoveries in Health and Disease

edited by

Mohamed Abouzid

submission deadline 31 Oct 2025 | 1 articles | Viewed by 461 | Submission Open

Keywords: vitamin D; vitamin D metabolites; metabolic pathways; vitamin D receptor; polymorphisms; pathogenesis; vitamin D deficiency

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Progress in Neonatal Pulmonary Biology

edited by

Fumihiko Namba

submission deadline 31 Oct 2025 | 1 articles | Viewed by 422 | Submission Open

Keywords: neonate; preterm infant; bronchopulmonary dysplasia; animal model; in vivo model; in vitro model; basic research; translational research; respiratory outcome; neurodevelopmental outcome

(This special issue belongs to the Section Molecular and Translational Medicine)

Role of Endothelial Cells in Cardiovascular Disease—2nd Edition

edited by

Lorenzo Falsetti

and

Vincenzo Zaccone

submission deadline 31 Oct 2025 | Viewed by 392 | Submission Open

Keywords: endothelial cells; endothelial dysfunction; cardiovascular disease; endothelial progenitor cells; atherosclerosis; thrombosis; vessel inflammation; regenerative medicine

(This special issue belongs to the Section Cell Biology and Pathology)

Advances in Inflammatory Skin Diseases

edited by

Angelo Ruggiero

Luca Potestio

and

Matteo Megna

submission deadline 31 Oct 2025 | Viewed by 364 | Submission Open

Keywords: inflammatory skin diseases; pathophysiology; therapeutic strategies; novel treatments; skin disorders

(This special issue belongs to the Section Immunology and Immunotherapy)

Gut–Brain Axis and Diabetes

edited by Nikolett Bódi

submission deadline 31 Oct 2025 | Viewed by 347 | Submission Open

Keywords: diabetes; gut– brain axis; enteric nervous system; central nervous system; microbiota; enteroendocrine cells; inflammation; immune responses

(This special issue belongs to the Section Endocrinology and Metabolism Research)

The Role of Oxidative Stress in Metabolic Syndrome

edited by

Bojlul Bahar

submission deadline 31 Oct 2025 | Viewed by 306 | Submission Open

Keywords: free radical; oxidative stress; ROS; NRF2; Keap1; metabolic syndrome; chronic inflammation; cardiovascular disease; obesity; diabetes

(This special issue belongs to the Section Molecular and Translational Medicine)

Unraveling the Epigenetic Blueprint: Exploring DNA Methylation and Its Integration with Omics in Health and Disease

edited by Priyadarshini Kachroo and Rinku Sharma

submission deadline 31 Oct 2025 | Viewed by 299 | Submission Open

Keywords: multiomics; networks; epigenomics; machine learning; causation; early-life exposures; aging; translational therapeutics; metabolomics; epigenomics; exposomics; proteomics; microbiome

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Epigenetic Regulation in Liver Metabolic Homeostasis and Disease

edited by Chengfei Jiang and Zhe Li

submission deadline 31 Oct 2025 | Viewed by 282 | Submission Open

Keywords: liver metabolism; epigenetic regulation; RNA modification; metabolic disorder; non-coding RNA; liver disease

(This special issue belongs to the Section Molecular and Translational Medicine)

Updates on Tissue Repair and Regeneration Pathways

edited by

Cornel Baltă

and

Oana-Maria Boldura

submission deadline 31 Oct 2025 | Viewed by 276 | Submission Open

Keywords: tissue repair; tissue regeneration; molecular pathways involved in repair and regeneration; extracellular matrix; drug delivery systems

(This special issue belongs to the Section Biomedical Engineering and Materials)

Post Tuberculosis Lung Disease from Lung Damage to the Loss of Lung Function

edited by

Oana Cristina Arghir

and Ariadna Petronela Fildan

submission deadline 31 Oct 2025 | Viewed by 261 | Submission Open

Keywords: post-tuberculosis lung disease (PTLD); post-TB conditions; TB sequelae; obstructive post-TB disease; post-TB syndromes

(This special issue belongs to the Section Molecular and Translational Medicine)

Novel Biomarkers and Technologies in the Research and Diagnosis of Human Diseases: Second Edition

edited by

Benjamin M. Liu

submission deadline 31 Oct 2025 | Viewed by 246 | Submission Open

Keywords: pathology; diseases; biomarkers; diagnosis; novel technologies

(This special issue belongs to the Section Immunology and Immunotherapy)

Mechanism and Modulation in Radiotoxicity

edited by

Stephanie Puukila

, Siddhita Mhatre and Janani Iyer

submission deadline 31 Oct 2025 | Viewed by 245 | Submission Open

Keywords: radiation; cellular damage; dose; tissue sensitivity; countermeasures

(This special issue belongs to the Section Cell Biology and Pathology)

Advances in Age-Related Diseases: Molecular Mechanisms, Treatments, and Clinical Implications

edited by

Stefano Cacciatore

and

Emanuele Marzetti

submission deadline 31 Oct 2025 | Viewed by 238 | Submission Open

Keywords: aging; age-related diseases; cellular senescence; mitochondrial dysfunction; inflammation and oxidative stress; biomarkers; precision medicine; pharmacological interventions; healthy aging; translational geriatric research

(This special issue belongs to the Section Molecular and Translational Medicine)

PET and SPECT Imaging for the Diagnosis of Neurodegenerative Diseases

edited by Paulina Gonzalez and

Carlo Colosimo

submission deadline 31 Oct 2025 | Viewed by 228 | Submission Open

Keywords: neurodegenerative diseases; PET imaging and diagnosis; neurological disorders; clinical PET imaging; positron emission tomography

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Molecular Insights and Translational Approaches in Musculoskeletal Disorders

edited by Priyanka Kushwaha

submission deadline 31 Oct 2025 | Viewed by 201 | Submission Open

Keywords: musculoskeletal disorders; osteoarthritis; rheumatoid arthritis

(This special issue belongs to the Section Molecular and Translational Medicine)

The Molecular Mechanisms of Hearing, Balance and Deafness

edited by

Francisco J. del Castillo

submission deadline 31 Oct 2025 | Viewed by 193 | Submission Open

Keywords: hearing; balance; deafness; molecular mechanisms; genetics; transcriptomics

(This special issue belongs to the Section Molecular and Translational Medicine)

Poly-Pharmacological Effects and Mechanisms of Phytochemicals

edited by

Jiawen Shou

submission deadline 31 Oct 2025 | Viewed by 182 | Submission Open

Keywords: phytochemicals; natural products; poly-pharmacology; novel application; research updates on phytochemicals

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Treatment of HIV Infection: Strategies, New Drugs and Drug Metabolism

edited by

Salvatore Martini

submission deadline 31 Oct 2025 | Viewed by 171 | Submission Open

Keywords: HIV; long-acting; efficacy; tolerability; adherence

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Photodynamic Therapy (4th Edition)

edited by

Stefano Bacci

submission deadline 31 Oct 2025 | Viewed by 141 | Submission Open

Keywords: antimicrobial photodynamic treatment; chronic wounds; inflammatory dermatoses; photobiology photochemistry; photochemotherapy; photosensitizing agents; skin cancer; oral mucosa

(This special issue belongs to the Section Immunology and Immunotherapy)

Tumor Microenvironment in Cancer: Basic Science, Artificial Intelligence, and Clinical Research

edited by Rada Amin

submission deadline 31 Oct 2025 | Viewed by 133 | Submission Open

Keywords: tumor microenvironment; cancer progression; malignancies; immunotherapy; therapy resistance; immune evasion

(This special issue belongs to the Section Cancer Biology and Oncology)

The Human Proteinomics in Disease, Diagnostics and Translation into Precision Medicine: Current Status and Future Prospects—2nd Edition

edited by

M. Walid Qoronfleh

submission deadline 31 Oct 2025 | Viewed by 129 | Submission Open

Keywords: proteomics; human proteome; systems biology; precision medicine; biomarker(s); disease pathogenesis; diagnostics; mass spectrometry; tandem mass spectrometry; LC-MS/MS; peptides and proteins; multiplex protein analysis; protein network; protein– protein interaction; splice variants; post-translational modifications; omics analysis; data integration; bioinformatics; artificial intelligence; deep learning

(This special issue belongs to the Section Molecular and Translational Medicine)

Stem Cell Therapy and Tissue Engineering

edited by

Nurettin Sahiner

submission deadline 31 Oct 2025 | Viewed by 121 | Submission Open

Keywords: stem cells; stem cell therapy; stem cell cancer therapy; hydrogels/cryogels; porous network biomaterials; tissue engineering

(This special issue belongs to the Section Cell Biology and Pathology)

Interaction Between Microbiota and Immunity in Health and Diseases

edited by Giuseppe Merra

submission deadline 31 Oct 2025 | Viewed by 108 | Submission Open

Keywords: microbiota; microbiome; inflammation; immunity; epithelial barrier

(This special issue belongs to the Section Microbiology in Human Health and Disease)

An Update on Mechanisms and Treatments for Thyroid Cancer in Current Oncology, 2nd Edition

edited by Zhilong Ai

submission deadline 31 Oct 2025 | Viewed by 107 | Submission Open

Keywords: thyroid cancer; mechanisms; treatments; biomarkers; precision medicine; infiltration; metastasis

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Type 2 Diabetes: Insulin Regulation and Therapeutic Strategies

edited by

Syed A. A. Rizvi

submission deadline 31 Oct 2025 | Viewed by 105 | Submission Open

Keywords: type 2 diabetes; insulin regulation; glycemic control; insulin resistance; therapeutic strategies; personalized medicine; GLP-1 receptor agonists; SGLT2 inhibitors; novel insulin formulations; non-insulin therapies

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Cancer-Associated Thrombosis: From Biomarkers to Diagnostic and Therapeutic Strategies to Optimize Treatment

edited by

Roberta Pancani

and Gualtiero Palareti

submission deadline 31 Oct 2025 | Viewed by 103 | Submission Open

Keywords: cancer-associated thrombosis; venous thrombosis; biomarkers; pulmonary embolism; precision medicine; diagnostic optimization

(This special issue belongs to the Section Cancer Biology and Oncology)

Cardiac and Vascular Diseases: Pathogenesis, Pharmacological Treatments, Advances in Therapies (3rd Edition)

edited by

Francesco Massari

and

Pietro Scicchitano

submission deadline 31 Oct 2025 | Viewed by 101 | Submission Open

Keywords: endothelial function; cardiomyopathies; cardiovascular pharmacology; cardiac therapeutics; noninvasive vascular treatments; molecular cardiac biomarkers; molecular vascular biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Immune Checkpoint Regulation and Signaling Pathways in Cancer

edited by Sreeja C. Sekhar

submission deadline 31 Oct 2025 | Viewed by 99 | Submission Open

Keywords: tumor-immune evasion and interaction; immune check point inhibition; PD-1/PDL-1 pathway; T-cell exhaustion and tumor microenvironment; single-cell profiling; therapeutic resistance; tumor-infiltrating cells; checkpoint inhibitors and immune modulation

(This special issue belongs to the Section Immunology and Immunotherapy)

Antipsychotics: 70 Years—2nd Edition

edited by

Giovanni Lentini

and

Serge Mignani

submission deadline 31 Oct 2025 | Viewed by 96 | Submission Open

Keywords: polypharmacology; multi-target drugs; emerging therapeutic targets; repurposing; complementary medicine; psychosis; schizophrenia; bipolar disorder; Alzheimer’ s disease

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

The Intricacies of Developmental and Epileptic Encephalopathies: A Journey Towards Innovative Therapies

edited by Muhammad Nauman Arshad and Paul Davies

submission deadline 31 Oct 2025 | Viewed by 96 | Submission Open

Keywords: cognitive; behavioral deficits

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Displaying special issue 301-350 on page 7 of 15.

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