Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Polycystic Ovary Syndrome Research: From Molecular Mechanisms to Therapeutic Strategies—2nd Edition
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1611 | Submission Open
Keywords: female infertility; endocrine disorder; metabolic disorder; polycystic ovary syndrome; polycystic ovariany morphology; hyperandrogenism; menstrual irregularity; theraputicsTherapeutics; oxidative stress; antioxidant
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Lipids and Lipid Metabolism in Cardiovascular Health and Disease
edited by Fei Luo
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1526 | Submission Open
Keywords: lipids; lipoproteins; lipid metabolism; cardiovascular health and disease; atherosclerotic cardiovascular disease; lipid-lowering therapy; triglyceride-lowering therapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Meningioma: Novel Diagnostic and Therapeutic Approaches
edited by Carlen A. Yuen
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1341 | Submission Open
Keywords: meningioma; atypical; anaplastic; PET DOTATATE; octreotide; Lutetium-177; targeted therapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Emerging Trends in the Study of Inherited Metabolic Disorders
edited by Sudeep Gautam
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1312 | Submission Open
Keywords: inherited metabolic disorders; glycogen storage diseases; genetically modified mouse models; liver and kidney disease; hepatocellular carcinoma; autophagy; diabetes mellitus; patient-derived organoids; gene therapy
(This special issue belongs to the Section Gene and Cell Therapy)
Microbial Infections and Sepsis: Pathophysiological Mechanisms and Therapeutic Approaches
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 1234 | Submission Open
Keywords: sepsis; cytokines; inflammation; bacteria; stem cell; molecular biology; flow cytometry; multiplex; MALDI-TOF-MS; RT-PCR
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Advanced Research on Fibromyalgia (3rd Edition)
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 1092 | Submission Open
Keywords: fibromyalgia; chronic fatigue syndrome; myofascial pain syndrome; diagnostic biomarkers; biomarkers for predicting treatment response; disability; rehabilitation; chronic pain; mutations and polymorphisms of genes related to fibromyalgia; epigenetics
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Immune Cell Biology: Insights from Molecular Perspectives
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 972 | Submission Open
Keywords: immune cell biology; cell signaling cascades; autoimmune disorders; immunoinflammatory pathways; hematological disorders
(This special issue belongs to the Section Cell Biology and Pathology)
Gliomas: Signaling Pathways, Molecular Mechanisms and Novel Therapies (2nd Edition)
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 962 | Submission Open
Keywords: glioma; molecular pathology; blood– brain barrier; immunotherapy; microenvironment; nanomedicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Brain Imaging and Cognitive Deficits in Psychiatric Disorders, 2nd Edition
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 749 | Submission Open
Keywords: cognitive deficits; psychiatric disorders; schizophrenia; brain imaging
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Mechanisms and Therapeutic Approaches for Hepatocellular Carcinoma
edited by Lanqi Gong, and Yu Zhang
submission deadline 31 Aug 2025 | 1 articles | Viewed by 736 | Submission Open
Keywords: hepatocellular carcinoma; HCC diagnosis and prognosis; HCC mechanisms; therapeutic resistance; immunotherapy; targeted therapy; personalized medicine; drug development; clinical trials; translational studies
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Cardiovascular Remodeling: Molecular Mechanisms and Therapeutic Targets
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 633 | Submission Open
Keywords: cardiac remodeling; vascular remodeling; ageing; pathogenesis; molecular mechanisms; diagnostics; therapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Recent Advances in Hypertension, Hypercholesterolemia and Type 2 Diabetes—2nd Edition
edited by
submission deadline 31 Aug 2025 | Viewed by 463 | Submission Open
Keywords: type 2 diabetes; hypertension; LDL-cholesterol; serum lipids; metabolic syndrome; cardiovascular disease; chronic complications; nephropathy
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Biomedicine in Dental and Oral Rehabilitation submission deadline 31 Aug 2025 | 1 articles | Viewed by 452 | Submission Open
Keywords: diagnosis; treatment; oral rehabilitation; dental and oral disease; biomedicine; biomaterial; regeneration; functional; esthetics
(This special issue belongs to the Section Biomedical Engineering and Materials)
New Perspectives in the Treatment of Head and Neck Vascular Malformations
edited by Paolo Gennaro
submission deadline 31 Aug 2025 | 1 articles | Viewed by 389 | Submission Open
Keywords: vascular anomalies; vascular malformations; AVMs; venous malformations; electrosclerotherapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Feature Reviews in Target Identification and Drug Discovery
edited by
submission deadline 31 Aug 2025 | Viewed by 381 | Submission Open
Keywords: drug discovery; biological target; bioactive compounds; pharmacology
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Crohn’s Disease and Ulcerative Colitis: From Pathophysiology to Novel Therapeutic Approaches (3rd Edition)
edited by and Junsik Sung
submission deadline 31 Aug 2025 | 1 articles | Viewed by 370 | Submission Open
Keywords: inflammatory bowel disease; Crohn’ s  disease; ulcerative colitis; chronic inflammation; pathophysiological mechanisms; therapeutic approaches; stem cell transplantation; fecal microbiota transplantation; gut microbiome; targeted therapies
(This special issue belongs to the Section Molecular and Translational Medicine)
Peptide Therapeutic Approaches for Cancer Treatment submission deadline 31 Aug 2025 | Viewed by 363 | Submission Open
Keywords: peptide therapeutics; cancer treatment; drug delivery systems; molecular imaging; bioinformatics; machine learning and artificial intelligence (AI); therapeutic targeting; peptide– drug conjugates; personalized medicine; immunotherapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Recent Advances in the Discovery of Novel Drugs on Natural Molecules, Second Edition submission deadline 31 Aug 2025 | Viewed by 343 | Submission Open
Keywords: natural compounds; bioactive peptides; peptidomimetics; microbial metabolites; polyphenols; genome mining; molecular modeling; therapeutic uses
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Advancements in the Treatment of Mesothelioma
edited by
submission deadline 31 Aug 2025 | Viewed by 327 | Submission Open
Keywords: mesothelioma; targeted therapy; diagnostics; checkpoint inhibitors; immunotherapy; chemotherapy; combination therapy
(This special issue belongs to the Section Molecular and Translational Medicine)
The Role of Immune Response in the Protection Against SARS-CoV-2 Infection
edited by
submission deadline 31 Aug 2025 | Viewed by 322 | Submission Open
Keywords: SARS-CoV-2; COVID-19; immune response; innate immune system; adaptative response; vaccines
(This special issue belongs to the Section Immunology and Immunotherapy)
Advanced Research in Antiviral Innate Immunity
edited by Junji Zhu
submission deadline 31 Aug 2025 | Viewed by 305 | Submission Open
Keywords: antiviral immunity; innate immune signaling; toll-like receptors (TLRs); RIG-I-like receptors (RLRs); cGAS-STING pathway; type I interferon; viral infection; post-translational modification (PTM); phase separation; host– pathogen interactions; therapeutic strategies
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Progress in Immunopharmacy
edited by and Shun-Hua Chen
submission deadline 31 Aug 2025 | 1 articles | Viewed by 298 | Submission Open
Keywords: immunopharmacy; immunopharmacology; immunomodulation; pharmacological intervention; immunotherapy; drug– immune system interaction; vaccine development; personalized pharmacotherapy
(This special issue belongs to the Section Immunology and Immunotherapy)
Multiple Sclerosis: Diagnosis and Treatment—3rd Edition
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 281 | Submission Open
Keywords: multiple sclerosis; pathogenesis; progressive MS; MRI; disease-modifying therapies; demyelinating disorders; cognitive dysfunction; intestinal microbiota
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Recent Advances in Biomedical Engineering for the Aging Population
edited by and Wen-Fong Wang
submission deadline 31 Aug 2025 | Viewed by 274 | Submission Open
Keywords: biomedical engineering; geriatric engineering; senescence; regenerative medicine; rehabilitation
(This special issue belongs to the Section Biomedical Engineering and Materials)
Respiratory Allergies: Insights from Molecular Perspectives
edited by Sara Manti and
submission deadline 31 Aug 2025 | Viewed by 271 | Submission Open
Keywords: pediatrics; allergology; pulmounology; acute and chronic respiratory diseases; congenital and acquired respiratory diseases; novel treatment.
(This special issue belongs to the Section Immunology and Immunotherapy)
Pathogenesis, Diagnosis and Treatment of Infectious Diseases
edited by
submission deadline 31 Aug 2025 | Viewed by 266 | Submission Open
Keywords: infection; infectious diseases; vaccination; antibiotics; antibiotic resistance; novel therapies; novel diagnosis; inflammaging; immunosenescence
(This special issue belongs to the Section Molecular and Translational Medicine)
Mitochondrial Dysfunction and Reactive Oxygen Species in Aging and Related Diseases
edited by and Gohar Azhar
submission deadline 31 Aug 2025 | Viewed by 256 | Submission Open
Keywords: mitochondrial dysfunction; aging; reactive oxygen species; mitochondrial dynamics; mitophagy; mitochondrial biogenesis; age-related disorders
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Roles of Extracellular Vesicles in Cancer Immunotherapy
edited by Shujing Liu and Zhiyuan Qin
submission deadline 31 Aug 2025 | Viewed by 254 | Submission Open
Keywords: extracellular vesicles; microvesicles; exosomes; cancer biology; cancer immunity; cancer immunotherapy; biomarkers; cancer vaccines; antigen presentation; drug delivery
(This special issue belongs to the Section Cancer Biology and Oncology)
The Role of Environmental Pollutants in Cancer and Chemoresistance submission deadline 31 Aug 2025 | Viewed by 243 | Submission Open
Keywords: environmental pollutants; cancer cells; therapeutic agents
(This special issue belongs to the Section Cancer Biology and Oncology)
Antimicrobial Stewardship in Solid Organ Transplantation: Optimizing Management of Infections Caused by Resistant Organisms
edited by Abhay Dhand
submission deadline 31 Aug 2025 | Viewed by 220 | Submission Open
Keywords: transplant; antimicrobial stewardship; quality; outcomes; infectious diseases; antimicrobial resistance
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Bleeding Disorders and Dental Implants
edited by
submission deadline 31 Aug 2025 | Viewed by 206 | Submission Open
Keywords: hemostasis; hemophilia; dental implant; oral surgery; anticoagulants
(This special issue belongs to the Section Molecular and Translational Medicine)
New Trends in Regional Anesthesia and Pain Management
edited by
submission deadline 31 Aug 2025 | Viewed by 203 | Submission Open
Keywords: regional anesthesia; ultrasound-guided/stimulator-guided nerve blocks; novel techniques for motor-sparing neural intervention; continuous catheter infusions; opioid-sparing techniques; perioperative pain management; novel local anesthetics; cadaveric dissection exploring the anatomical knowledge of motor-sparing techniques; modalities (techniques; technologies; or drug regimen) to prolong the effect of local anesthetics; ERAS-related studies; AI applications in regional anesthesia and pain management; innovations and protocols/curriculum regarding regional anesthesia and pain management in the battlefield; studies comparing new technologies/simulation (such as EpiFaith; SPRint PNS system; or CompuFlo) with traditional methods in improving regional anesthesia and pain management; regenerative medicine; nutritional pain medicine; application of bone marrow aspirate concentration or other stem cell components in pain medicine; multidisciplinary/comprehensive care program; transarterial embolization for pain management; joint denervation for pain management
(This special issue belongs to the Section Molecular and Translational Medicine)
Recent Advances in Adipokines (3nd Edition)
edited by
submission deadline 31 Aug 2025 | Viewed by 183 | Submission Open
Keywords: adiponectin; receptor; agonist; biomarker; inflammation; cancer
(This special issue belongs to the Section Cell Biology and Pathology)
Emerging Trends in Malignant Mesothelioma
edited by Yuan Xu
submission deadline 31 Aug 2025 | Viewed by 170 | Submission Open
Keywords: mesothelioma; asbestos; novel therapeutic strategies; treatment resistance; multi-omics analysis
(This special issue belongs to the Section Cancer Biology and Oncology)
Epigenetics in the Perioperative Setting
edited by Rump Katharina
submission deadline 31 Aug 2025 | Viewed by 153 | Submission Open
Keywords: epigenetics; perioperative setting; surgical stress; anesthesia; gene expression; cognitive impairment; postoperative delirium; postoperative cognitive dysfunction (POCD); neuroinflammation; therapeutic approaches
(This special issue belongs to the Section Immunology and Immunotherapy)
Emerging Insights in Thoracic Diseases: From Diagnostics to Biomarkers and Therapeutic Implications Through Interdisciplinarity submission deadline 31 Aug 2025 | Viewed by 145 | Submission Open
Keywords: chronic obstructive pulmonary disease; acute respiratory diseases; cardionephrology; interstitial lung disease; interventional cardiology; pulmonary fibrosis; tuberculosis; research methodology; biomarkers; therapeutics; artificial intelligence
(This special issue belongs to the Section Molecular and Translational Medicine)
The Role of Cytokines in Health and Disease: 3rd Edition
edited by
submission deadline 31 Aug 2025 | Viewed by 144 | Submission Open
Keywords: cytokine; chemokine; neurodegenerative disease; cancer; inflammatory mediator; diagnosis; biomarker
(This special issue belongs to the Section Cell Biology and Pathology)
Genetic Insights and Pharmacogenomic Approaches in Cancer Treatment submission deadline 31 Aug 2025 | Viewed by 142 | Submission Open
Keywords: pharmacogenetics; genetic basis; cancer treatments
(This special issue belongs to the Section Cancer Biology and Oncology)
Head and Neck Cancer: From Mechanisms to Therapeutic Approaches—Advances and Challenges submission deadline 31 Aug 2025 | Viewed by 131 | Submission Open
Keywords: head and neck cancers; target therapy; biomarkers; molecular targets; translational research; pathogenesis; prognosis; diagnostic tool
(This special issue belongs to the Section Cancer Biology and Oncology)
Feature Reviews in Gastrointestinal and Liver Diseases
edited by
submission deadline 31 Aug 2025 | Viewed by 118 | Submission Open
Keywords: gastrointestinal diseases; gut– brain interaction; gut microbiota; inflammatory bowel disease; liver disorders; Crohn’ s disease; cancer; fatty liver disease; malnutrition
(This special issue belongs to the Section Molecular and Translational Medicine)
Pathogenesis and Treatment of Ophthalmic Diseases
edited by
submission deadline 31 Aug 2025 | Viewed by 117 | Submission Open
Keywords: ophthalmology; AI; ocular; eye diseases; retina; cornea; glaucoma; neuro-ophthalmology
(This special issue belongs to the Section Molecular and Translational Medicine)
Epigenetics and Immune Perspectives in Cancer: Overcoming Therapy Resistance
edited by
submission deadline 31 Aug 2025 | Viewed by 111 | Submission Open
Keywords: epigenetics; immunotherapy; therapy resistance; tumor microenvironment; DNA methylation; histone modifications; dietary intervention; non-coding RNAs; immune evasion; combination therapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Progress in Cytotoxicity of Biomaterials
edited by Lakkamraju Vijayalakshmi
submission deadline 31 Aug 2025 | Viewed by 107 | Submission Open
Keywords: biomaterial cytotoxicity; biocompatibility assessment; in vitro and in vivo toxicity; surface modification; nanomaterials in medicine; oxidative stress and inflammation; tissue engineering materials; drug delivery systems; biodegradable polymers; regulatory perspectives on biomaterial safety
(This special issue belongs to the Section Biomedical Engineering and Materials)
Central Role of Mitochondrial Oxidative Stress in the Pathophysiology of Disorders (2nd Edition)
edited by and André Quincozes-Santos
submission deadline 31 Aug 2025 | Viewed by 98 | Submission Open
Keywords: mitochondrial dysfunction; reactive oxygen species; bioenergetics; mitochondrial quality control; pathologies; protective agents
(This special issue belongs to the Section Molecular and Translational Medicine)
Neurodegenerative Diseases: From Mechanisms to Therapeutic Approaches, 2nd Edition submission deadline 31 Aug 2025 | Viewed by 91 | Submission Open
Keywords: neurodegenerative diseases; neurons; mechanism
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Imaging Technology for Human Diseases
edited by Emanuele David
submission deadline 31 Aug 2025 | Viewed by 85 | Submission Open
Keywords: technological advances; imaging; X-ray; mammography; CT; MRI; ultrasound; angiography
(This special issue belongs to the Section Biomedical Engineering and Materials)
Osteoarthritis: Molecular Pathways and Novel Therapeutic Strategies—2nd Edition
edited by , , and Andrea Pantalone
submission deadline 31 Aug 2025 | Viewed by 84 | Submission Open
Keywords: osteoarthritis; cartilage; pain; orthopedics; rehabilitation
(This special issue belongs to the Section Molecular and Translational Medicine)
Nanoparticle-Labeled Exosomes as Theranostic Agents
edited by Karrer M. Alghazali
submission deadline 31 Aug 2025 | Viewed by 82 | Submission Open
Keywords: exosomes; nanotheranostic agent; nanoparticles; exosome labeling; photothermal therapy; drug delivery vehicle; imaging probe
(This special issue belongs to the Section Cell Biology and Pathology)
Tumor Biomarkers in Gynecology—2nd Edition submission deadline 31 Aug 2025 | Viewed by 76 | Submission Open
Keywords: gynecological cancers; precision medicine; biomarkers
(This special issue belongs to the Section Cancer Biology and Oncology)
Exploring Conventional and Alternative Animal Models in Biomedical Research (Biomedicines) submission deadline 31 Aug 2025 | Viewed by 73 | Submission Open
Keywords: disease modelling; drug discovery and delivery; toxicology; personalized medicine; bioengineering; computational biology; ethical considerations; translational research
(This special issue belongs to the Section Molecular and Translational Medicine)
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