Pathophysiology and Therapeutic Innovations in Skin and Appendage Disorders
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 51
Special Issue Editor
2. Institute for Regenerative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
3. Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
Interests: developmental biology; cutaneous biology; stem cell; epigenetic regulation; dry eye disease
Special Issue Information
Dear Colleagues,
The skin and its appendages, including hair follicles and exocrine glands, are intricate organs that require precise molecular regulation for proper development, homeostasis, and repair. Dysregulation in these processes can lead to a wide range of disorders, from common dermatological conditions such as psoriasis, atopic dermatitis, acne, and alopecia to more severe malignancies like melanoma and squamous cell carcinoma. This Special Issue, "Pathophysiology and Therapeutic Innovations in Skin and Appendage Disorders", aims to explore the underlying mechanisms and emerging therapeutic strategies for these conditions, bridging the gap between fundamental research and clinical translation.
Key topics include, but are not limited to, the following:
- Developmental and homeostatic mechanisms;
- Disease drivers in psoriasis, atopic dermatitis, acne, alopecia, and cutaneous cancers;
- Innovative therapies, such as small-molecule inhibitors, biologics, and regenerative approaches;
- Genetic and epigenetic factors in skin disorders.
We invite contributions that explore the molecular mechanisms regulating skin and appendage development, homeostasis, and tumorigenesis. By integrating multidisciplinary approaches, we aim to advance our understanding of these complex processes and improve therapeutic outcomes for patients. This Special Issue provides a platform for researchers and clinicians to share their latest findings and innovative strategies, fostering a collaborative environment dedicated to advancing the field of dermatology and cutaneous biology.
Dr. Xuming Zhu
Guest Editor
Manuscript Submission Information
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Keywords
- skin disorders
- skin development
- skin pathophysiology
- tumorigenesis
- psoriasis
- atopic dermatitis
- acne
- innovative therapies
- molecular dermatology
- translational skin research
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