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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cutting-Edge Research on Cardiovascular Nuclear Medicine

edited by Pipitsa N. Valsamaki

submission deadline 31 Aug 2025 | Viewed by 71 | Submission Open

Keywords: transthyretin cardiac amyloidosis; molecular mechanisms; nuclear medicine imaging (SPECT; SPECT/CT; PET/CT); treatment advancements

(This special issue belongs to the Section Molecular and Translational Medicine)

Obesity and Obesity-Related Pathology

edited by

Adriana Grigoraș

submission deadline 31 Aug 2025 | Viewed by 69 | Submission Open

Keywords: obesity; obesity-related cardiovascular diseases; obesity-related chronic kidney diseases; diabetes mellitus; depression; obesity-related cancer; adipose tissue; adipocytes; cancer-associated adipocytes; obesity therapies

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Pathogenesis, Diagnosis and Treatment of Cardiomyopathy and Cardiac Arrhythmias

edited by Sung Il Im

submission deadline 30 Sep 2025 | 6 articles | Viewed by 11429 | Submission Open

Keywords: arrhythmia; cardiomyopathy; pathogenesis; diagnosis

(This special issue belongs to the Section Molecular and Translational Medicine)

State-of-the-Art Drug Discovery and Development in Poland (2nd Edition)

edited by

Aleksandra Romaniuk-Drapała

submission deadline 30 Sep 2025 | 7 articles | Viewed by 9438 | Submission Open

Keywords: in silico drug target profiling; drug delivery systems; drug– drug interactions; target-based screening; phenotypic screening; pharmaceutical modeling; computational chemistry; targeted therapy; biomarkers; bioimaging

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Neurodevelopmental Disorders: From Pathophysiology to Novel Therapeutic Approaches—2nd Edition

edited by Nader Perroud and Markus Mathaus Kosel

submission deadline 30 Sep 2025 | 4 articles | Viewed by 6371 | Submission Open

Keywords: intellectual disability; autism spectrum disorder; attention-deficit/hyperactivity disorder; drug treatment; neuroimaging

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Molecular Characteristics of Cerebral Ischemia and Their Therapeutic Applications

edited by E-Jian Lee and Shengyang Huang

submission deadline 30 Sep 2025 | 3 articles | Viewed by 4807 | Submission Open

Keywords: cerebral ischemia; molecular mechanisms; pathophysiology; biomarkers; therapeutic strategies; neuroprotection; ischemic stroke; neuro-inflammation; translational research; neuroplasticity; neurophysiology; neuroscience; neuroelectrophysiology

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Multidisciplinary Management of Rare Head and Neck Tumors: The Importance of Knowing and Dealing with Them

edited by

Francesco Perri

submission deadline 30 Sep 2025 | 3 articles | Viewed by 4741 | Submission Open

Keywords: rare head and neck cancers; translational research; therapeutic targets

(This special issue belongs to the Section Cancer Biology and Oncology)

Ubiquitylation and Deubiquitylation in Health and Diseases

edited by Tadashi Nakagawa

submission deadline 30 Sep 2025 | 5 articles | Viewed by 4586 | Submission Open

Keywords: ubiquitin ligase; deubiquitinase; health; disease; therapeutics; eukaryotic cells

(This special issue belongs to the Section Molecular and Translational Medicine)

Pathogenesis, Diagnosis and Treatment of Hematologic Malignancies

edited by

Michele Gottardi

submission deadline 30 Sep 2025 | 5 articles | Viewed by 4488 | Submission Open

Keywords: hematologic malignancies; pathogenesis; diagnosis; treatment; targeted therapy; molecular research

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Mechanisms and Treatment of Rheumatic Diseases

edited by Ruxandra Ionescu and

Daniela Opris-Belinski

submission deadline 30 Sep 2025 | 2 articles | Viewed by 4452 | Submission Open

Keywords: rheumatology; immune-mediated rheumatic diseases; biologics; DMARDs; arthritis; lupus; vasculitis; spondyloarthritis; targets

(This special issue belongs to the Section Molecular and Translational Medicine)

Epigenetics and Metabolic Disorders

edited by Patrik Krumpolec

submission deadline 30 Sep 2025 | 1 articles | Viewed by 4006 | Submission Open

Keywords: metabolic diseases; epigenetics; DNA methylation; histone modification; non-coding RNA (ncRNA)-mediated gene regulation; heredity; environmental factors

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Hepato-Pancreato-Biliary Cancers: Pathogenesis, Comorbidities and Therapy Updated

edited by

Consolato M. Sergi

and

Paola Di Carlo

submission deadline 30 Sep 2025 | 4 articles | Viewed by 3981 | Submission Open

Keywords: liver; bile; cancer; microbiome; pathogenesis; MiRNA; jaundice; disease; therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Advancements in Lung Cancer Precision Oncology Research and Treatments

edited by

Panagiotis Paliogiannis

Giuseppe Palmieri

and Francesca Colonese

submission deadline 30 Sep 2025 | 5 articles | Viewed by 3548 | Submission Open

Keywords: lung; cancer; NSCLC; targeted therapies; immunotherapy; precision oncology; EGFR; KRAS; ALK; ROS1

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Angiogenesis, Inflammation, and Oxidative Stress in Inflammatory Bowel Diseases

edited by

Mihail Virgil Boldeanu

and Dan Ionuț Gheonea

submission deadline 30 Sep 2025 | 3 articles | Viewed by 3526 | Submission Open

Keywords: inflammatory bowel disease; angiogenesis; inflammation; oxidative stress

(This special issue belongs to the Section Molecular and Translational Medicine)

Cardiovascular Diseases in the Era of Precision Medicine

edited by

Panteleimon Pantelidis

and

Polychronis E. Dilaveris

submission deadline 30 Sep 2025 | 4 articles | Viewed by 3421 | Submission Open

Keywords: cardiology; precision medicine; cardiovascular diseases; genomics; proteomics; multi-omics; personalized therapy; diagnostic tools; imaging technologies; biosignals

(This special issue belongs to the Section Molecular and Translational Medicine)

Retinal Vascular Disorders: New Insights into Pathogenesis, Diagnosis and Treatment

edited by Irini P. Chatziralli

submission deadline 30 Sep 2025 | 2 articles | Viewed by 3159 | Submission Open

Keywords: diabetic retinopathy; retinal vein occlusion; retinal artery occlusion; sickle-cell retinopathy; optical coherence tomography; widefield imaging; OCT angiography

(This special issue belongs to the Section Molecular and Translational Medicine)

The Role of NK Cells in Cancer Immunotherapy: Mechanisms, Evasion Strategies, and Therapeutic Advances

edited by Maria Eugenia Garcia Rubino

submission deadline 30 Sep 2025 | 1 articles | Viewed by 3060 | Submission Open

Keywords: NK cells; cancer immunotherapy; tumor evasion; cytotoxicity; CAR-NK; cytokines; IL-2; immunotherapy; tumor microenvironment

(This special issue belongs to the Section Cancer Biology and Oncology)

Pharmaceutical Treatments for Typical CKD Comorbidities

edited by

Annalisa Noce

and

Manuela Di Lauro

submission deadline 30 Sep 2025 | 2 articles | Viewed by 3048 | Submission Open

Keywords: natural bioactive compounds; adjuvant treatment; protein energy wasting; mineral bone disorders; metabolic acidosis; hyperhomocysteinemia; uremic sarcopenia; PLADO diet; anemia in CKD

(This special issue belongs to the Section Molecular and Translational Medicine)

Pollutants and Human Health: Focus on Molecular-Level Research

edited by

Elisa Cairrao

and

Margarida Lorigo

submission deadline 30 Sep 2025 | 1 articles | Viewed by 2874 | Submission Open

Keywords: environmental exposure; emerging pollutants; human and ecosystem health; environmental risk assessment; adverse outcome pathways; human risk assessment; endocrine-disrupting chemicals; cardiovascular endocrinology; neurovascular endocrinology; reproductive toxicology

(This special issue belongs to the Section Molecular and Translational Medicine)

An Update on Transplantation Immunology

edited by Hui-Yun Cheng

submission deadline 30 Sep 2025 | 1 articles | Viewed by 2804 | Submission Open

Keywords: transplantation; immunology; immunosuppression; immunomodulation

(This special issue belongs to the Section Immunology and Immunotherapy)

Advanced Research in Cardiovascular and Hemodynamic Monitoring

edited by

Dustin R. Fraidenburg

and Scott T. Benken

submission deadline 30 Sep 2025 | 3 articles | Viewed by 2766 | Submission Open

Keywords: vasopressors; hemodynamic monitoring; hypotension; shock; cardiac arrest; heart rate; blood pressure; critical care; intensive care unit

(This special issue belongs to the Section Molecular and Translational Medicine)

State-of-the-Art Hepatic and Gastrointestinal Diseases in Germany

edited by

Christa Büchler

submission deadline 30 Sep 2025 | 2 articles | Viewed by 2464 | Submission Open

Keywords: biomarker; prevalence; Germany; inflammatory bowel disease; cancer

(This special issue belongs to the Section Molecular and Translational Medicine)

Immunometabolic Determinants of Gut–Liver Axis Health

edited by

Jose Moisés Laparra

submission deadline 30 Sep 2025 | 1 articles | Viewed by 2382 | Submission Open

Keywords: gut microbiota; 'entero-hepatic' axis; gut– liver axis; immunometabolism

(This special issue belongs to the Section Immunology and Immunotherapy)

Advancements in Neuroscience: A Special Issue in Honour of Ramón Y Cajal

edited by

Maria A. Bonifacio

submission deadline 30 Sep 2025 | 1 articles | Viewed by 2275 | Submission Open

Keywords: neurobiology; neuroscience; histology; imaging; nervous system; brain; neurodegenerative diseases; neurodevelopmental disorders; molecular biology; big data mining

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Exploring Protein-Ligand Interaction: Key Insights for Drug Discovery

edited by

Aurica Precupas

and

Vlad T. Popa

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1992 | Submission Open

Keywords: protein; ligand; bio(macro)molecule; drug; interaction; binding; spectroscopy; calorimetry; molecular docking; molecular dynamics simulation

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Latest Research in Post-COVID (Long COVID): Pathological and Treatment Studies of Sequelae and Complications—3rd Edition

edited by

César Fernández-de-las-Peñas

submission deadline 30 Sep 2025 | 4 articles | Viewed by 1781 | Submission Open

Keywords: COVID-19; long COVID; pain; function; fatigue; dyspnoea; vaccine

(This special issue belongs to the Section Molecular and Translational Medicine)

Organoid, Organ-on-Chip and Advanced 2D/3D Models for Human Tissue Engineering Applications

edited by

Ahmad Salti

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1608 | Submission Open

Keywords: organoid; organ-on-chip; 2D/3D model; tissue engineering; induced pluripotent stem cells; in vitro model

(This special issue belongs to the Section Biomedical Engineering and Materials)

The Treatment of Cardiovascular Diseases in the Critically Ill

edited by

Vasileios Vazgiourakis

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1360 | Submission Open

Keywords: septic cardiomyopathy; takotsubo syndrome; cardiac arrhythmias; acute coronary syndromes; antiplatelets; antithrombotics

(This special issue belongs to the Section Molecular and Translational Medicine)

Feature Reviews in Biomaterials for Oral Diseases

edited by

Oliver Schierz

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1290 | Submission Open

Keywords: dental composites; ceramics; zirconia; polymers; polyaryletherketone; polyoxymethylene; titanium; bone graft materials; implants

(This special issue belongs to the Section Biomedical Engineering and Materials)

Synaptic Function and Modulation in Health and Disease

edited by Jean-Marie C. Bouteiller

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1085 | Submission Open

Keywords: synaptic function; synaptic plasticity; neurotransmitter release; receptor dynamics

(This special issue belongs to the Section Molecular and Translational Medicine)

Vascular Pathologies in the Omics-Era

edited by

Deepti Diwan

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1010 | Submission Open

Keywords: vascular pathology; blood vessels; omics era; epigenetics; genomics; transcriptomics; proteomics; metabolomics

(This special issue belongs to the Section Cell Biology and Pathology)

Mechanomedicine: Exploring Mechanobiology at the Intersection of Engineering and Biology

edited by

Wenqiang Du

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1004 | Submission Open

Keywords: mechanomedicine; mechanobiology; microphysiological systems; bioengineering; forces

(This special issue belongs to the Section Biomedical Engineering and Materials)

Molecular Regulation of Spermatozoa—Second Edition

edited by

Atefeh Najafi

submission deadline 30 Sep 2025 | 1 articles | Viewed by 629 | Submission Open

Keywords: spermatogenesis; spermiogenesis; sperm; capacitation; acrosome reaction; hyperactivation; fertilization; male infertility; antioxidants; redox regulation

(This special issue belongs to the Section Cell Biology and Pathology)

Pathogenesis, Diagnosis and Treatment of Cardiomyopathy and Cardiac Arrhythmias (2nd Edition)

edited by Sung Il Im

submission deadline 30 Sep 2025 | 1 articles | Viewed by 576 | Submission Open

Keywords: arrhythmia; cardiomyopathy; pathogenesis; diagnosis

(This special issue belongs to the Section Molecular and Translational Medicine)

Innovative Approaches in Drug Discovery

edited by Jitendra Gour

submission deadline 30 Sep 2025 | Viewed by 491 | Submission Open

Keywords: PROTACs; molecular glue; personalized medicine; high-throughput screening (HTS); targeted therapy; drug repurposing; safety profiles

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Recent Research on Dry Eye

edited by Liat Gantz

submission deadline 30 Sep 2025 | 1 articles | Viewed by 485 | Submission Open

Keywords: dry eye; meibomian gland dysfunction; ocular surface disease

(This special issue belongs to the Section Molecular and Translational Medicine)

Impacts of Exercise, Nutrition, Obesity, Metabolism and Ageing on Regenerative Medicine and Their Applications in Tissue Engineering and Therapeutics

edited by

Abdelaziz Ghanemi

submission deadline 30 Sep 2025 | 1 articles | Viewed by 465 | Submission Open

Keywords: obesity; exercise; nutrition (diet); obesity; metabolism; ageing; regenerative medicine; tissue engineering; therapeutics

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Next-Generation Nanoparticles: Innovations in Biomedical Applications and Theranostics

edited by

Md Amdadul Huq

submission deadline 30 Sep 2025 | 1 articles | Viewed by 419 | Submission Open

Keywords: nanoparticles; nanoconjugates; antimicrobial agents; anticancer agents; biomedical applications

(This special issue belongs to the Section Nanomedicine and Nanobiology)

New Horizons in Enzyme Inhibitor Discovery: Targets, Design and Evaluation

edited by Chenzhou Hao, Jing Guo, Yin Sun and Tongchao Liu

submission deadline 30 Sep 2025 | Viewed by 385 | Submission Open

Keywords: enzyme inhibitors; drug design; inhibitor screening; medicinal chemistry; targets validation; structure– activity relationship; structure– property relationship

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Medical Imaging in Brain Tumor: Charting the Future

edited by

Subrata Bhattacharjee

and

Mansoor Hayat

submission deadline 30 Sep 2025 | Viewed by 381 | Submission Open

Keywords: brain tumor diagnosis; artificial intelligence (AI) in medical imaging; imaging biomarkers for brain tumor; detection; segmentation and classification; radiomics and radiogenomics; precision oncology; deep learning and machine learning; neuro oncology; digital pathology; treatment response monitoring

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advanced Research on the Role of Biogenic Amines in Physiological and Pathological Conditions

edited by

Pellegrino Lippiello

Luisa Speranza

and

Maria Grazia Ferraro

submission deadline 30 Sep 2025 | Viewed by 345 | Submission Open

Keywords: biogenic amines; memory; synapse; depression; anxiety; schizophrenia; glioma and neurodegenerative diseases

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Therapeutic Strategies and Precision Medicine in Solid Tumors and Metastasis—2nd Edition

edited by

Silvia Di Agostino

and

Vittoria Rago

submission deadline 30 Sep 2025 | 1 articles | Viewed by 324 | Submission Open

Keywords: kinase inhibitor; immunotherapy; chemotherapy; precision molecular therapy; biomarkers; synthetic lethality; theranostics; drug repurposing; radiomics

(This special issue belongs to the Section Cancer Biology and Oncology)

The Art of ART (Assisted Reproductive Technologies)

edited by

Dimitrios Papageorgiou

submission deadline 30 Sep 2025 | 1 articles | Viewed by 320 | Submission Open

Keywords: assisted reproductive technologies; infertility diagnosis; intrauterine insemination (IUI); intracytoplasmic sperm injection (ICSI); in vitro fertilization (IVF); embryo implantation; oocyte quality; preimplantation genetic testing; mitochondrial replacement therapy; follicular recruitment; reproductive medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Eosinophil: Current Status and Future Perspectives

edited by

Ildiko Horvath

submission deadline 30 Sep 2025 | Viewed by 319 | Submission Open

Keywords: eosinophils; predictive biomarker; severe asthma; blood cell count; anti-eosinophils; mortality

(This special issue belongs to the Section Cell Biology and Pathology)

Hearing Loss: Mechanisms and Targeted Interventions

edited by Pavlidis Pavlos

submission deadline 30 Sep 2025 | Viewed by 309 | Submission Open

Keywords: hearing loss; syndromes; anatomy and physiology of the ear; implants; cochlear implantation; diseases of the middle ear; rehabilitation

(This special issue belongs to the Section Cell Biology and Pathology)

Advanced Research in Thyroid and Parathyroid Diseases

edited by Anping Su

submission deadline 30 Sep 2025 | 1 articles | Viewed by 308 | Submission Open

Keywords: thyroid cancer treatment; tumor microenvironment; immunotherapy; targeted therapy; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

New Advances in Ovarian Cancer

edited by

Zhenshan Yang

submission deadline 30 Sep 2025 | Viewed by 304 | Submission Open

Keywords: ovarian cancer; biomarkers; cell biology; gene regulation; target therapy; therapeutic resistance; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

Stem Cell Therapy: Traps and Tricks

edited by

Martina Perše

and Željka Večerić-Haler

submission deadline 30 Sep 2025 | 1 articles | Viewed by 303 | Submission Open

Keywords: mesenchymal stem cells; MSC therapy; preclinical research; regenerative medicine

(This special issue belongs to the Section Biomedical Engineering and Materials)

Diagnostic and Therapeutic Challenges of CAR-T Cell Therapy

edited by Vincenzo Maria Perriello

submission deadline 30 Sep 2025 | Viewed by 302 | Submission Open

Keywords: CAR-T therapy; immunotherapy; relapsed/refractory diffuse large B cell lymphoma (r/r DLBCL); relapsed/refractory mantle cell lymphoma (r/r MCL); B-acute lymphoblastic leukemia (r/r B-ALL); bridging therapy; cytokine release syndrome (CRS); immune effector cell associated neurotoxicity (ICANS); biomarkers; PET/CT assessment after CAR-T cell therapy

(This special issue belongs to the Section Gene and Cell Therapy)

The Role of the Myofibroblast in Fibrosis and Cancer

edited by Bingrui Li, Xuebin Fu, Xiaodong Zou and Xue Wan

submission deadline 30 Sep 2025 | Viewed by 289 | Submission Open

Keywords: fibroblasts and myofibroblasts; fibrosis (organ and tissue fibrosis); cancer; tissue injury; extracellular matrix

(This special issue belongs to the Section Molecular and Translational Medicine)

Displaying special issue 351-400 on page 8 of 14.

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