Nervous System Injury and Repair: From Molecular Mechanism to Therapeutic Perspectives
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 409
Special Issue Editor
Interests: nervous system injury; neuronal death; axon injury; oxidative stress; excitotoxicity; neuroinflammation; stroke; trauma
Special Issue Information
Dear Colleagues,
Nervous system injury is a leading risk factor for disability and death in the absence of effective treatment. The pathogeneses of neural damage are highly complex and involve factors such as energy deficiency, ion imbalance, and metabolic disorders. Following neural injury, a cascade of events including excitotoxicity, inflammation, and oxidative stress contributes to the death of neurons and non-neuronal cells (such as astrocytes and microglial cells) in the brain, ultimately resulting in outcomes like motor dysfunction, cognitive impairment, and other neurological deficits.
Using various of neural injury models helps investigate the cellular and molecular regulatory mechanisms underlying neural damage and provide neuroprotection strategies. However research progress and treatment efficacy remain limited for subsets of nervous system injuries. Therefore, further investigation into molecular targets and pharmacological neuroprotection is urgently needed.
Dr. Shuchao Wang
Guest Editor
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Keywords
- nervous system injury
- neuron
- astrocytes
- microglial cells
- excitotoxicity
- inflammation
- oxidative stress
- neuroprotection
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