Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Application of Biomedical Materials in Cancer Therapy
edited by Rui Sang
submission deadline 31 Jul 2025 | Viewed by 232 | Submission Open
Keywords: biomedical materials; cancer therapy; drug delivery systems; biomaterials synthesis; imaging agents; tissue engineering; regenerative medicine; tumor microenvironment; targeted therapy; biocompatibility
(This special issue belongs to the Section Biomedical Engineering and Materials)
Innovations in Nanomedicine for Disease Management
edited by Anna Valentino and
submission deadline 31 Jul 2025 | Viewed by 223 | Submission Open
Keywords: nanomedicine; nanoparticles; smart drug delivery; personalized medicine; minimally invasive treatments; gene therapy; regenerative medicine
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Diabetes Mellitus: Pharmacological Innovations and Related Therapeutic Benefits submission deadline 31 Jul 2025 | Viewed by 160 | Submission Open
Keywords: therapy of diabetes mellitus; pharmacological innovations; incretins; GLP-1 receptor agonists; SGLT-2 inhibitors; weight control; diabetes-related cardiovascular risk; non-glycemic benefits of diabetes drugs; diabetes-related technologies; diabetes outcomes
(This special issue belongs to the Section Molecular and Translational Medicine)
Novel Strategies for Oncogene-Addicted Lung Cancers: Not Rare Anymore submission deadline 31 Jul 2025 | Viewed by 150 | Submission Open
Keywords: target therapy; EMT; biomarkers; cancer mutations; preclinical models
(This special issue belongs to the Section Cancer Biology and Oncology)
The Renin–Angiotensin System in Immune Regulation: Roles in Blood, Vessels, and Inflammation
edited by Chao Liu
submission deadline 31 Jul 2025 | Viewed by 144 | Submission Open
Keywords: renin– angiotensin system; immune regulation; vascular biology; inflammation; T cells; macrophages; neutrophils; angiotensin II; ACE2; stem cells
(This special issue belongs to the Section Immunology and Immunotherapy)
Recent Advances in Oral Medicine—2nd Edition submission deadline 31 Jul 2025 | Viewed by 136 | Submission Open
Keywords: oral medicine; oral manifestations of systemic conditions; drug-induced lesions; oral pathologies; head and neck cancer; autoimmune; oral lesions; bisphosphonates; systemic pharmacotherapy; infectious diseases
(This special issue belongs to the Section Molecular and Translational Medicine)
Demyelinating Diseases: Pathophysiology and Emerging Therapeutic Targets
edited by Jude Taylor
submission deadline 31 Jul 2025 | Viewed by 127 | Submission Open
Keywords: demyelinating diseases; pathophysiological processes; diagnostic accuracy and predicting disease; emerging strategies
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
New Insights in Hypoxic Response Modulation
edited by Rafał Bartoszewski
submission deadline 31 Jul 2025 | 1 articles | Viewed by 120 | Submission Open
Keywords: hypoxia; oxygen homeostasis; oxidative damage; cell death; ischemic events; stroke; myocardial infarction; tumor microenvironment (TME); noncoding RNA; MicroRNAs; long noncoding RNAs; PiRNA; hypoxia-inducible factors (HIFs); targeted delivery; hypoxic cells; regulatory networks; therapeutic opportunities
(This special issue belongs to the Section Cell Biology and Pathology)
Current Trends in Diabetic Foot Disease
edited by Xuefeng Yu
submission deadline 31 Jul 2025 | Viewed by 107 | Submission Open
Keywords: diabetes; diabetic foot; endocrinology; metabolic disease
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Advances in Head and Neck Cancer: Mechanisms, Diagnosis, and Therapeutic Progress
edited by and Hideto Saijo
submission deadline 31 Jul 2025 | Viewed by 96 | Submission Open
Keywords: head and neck cancer; oral cancer; laryngeal cancer; nasopharyngeal cancer; thyroid cancer; diagnostic and treatment strategies
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Precision Cancer Therapy
edited by
submission deadline 31 Jul 2025 | Viewed by 92 | Submission Open
Keywords: personalized cancer therapy; targeted therapy; immunotherapy; cancer genomics; cancer biomarker; liquid biopsy; CAR-T cell therapy; kinase inhibitor; combination therapy; molecular profiling
(This special issue belongs to the Section Cancer Biology and Oncology)
Biochemical and Molecular Perspectives on Engineered Nanoparticles for Cancer Therapy submission deadline 31 Jul 2025 | Viewed by 87 | Submission Open
Keywords: cancer; oxidative stress; engineered nanoparticles (ENPs); drug delivery; biochemical processes; ferroptosis; apoptosis; cell death; molecular interactions; tumor microenvironment
(This special issue belongs to the Section Cancer Biology and Oncology)
Glioblastoma: From Pathology to Novel Therapeutic Approaches
edited by Carlen A. Yuen
submission deadline 31 Jul 2025 | Viewed by 70 | Submission Open
Keywords: glioblastoma; EGFR; TERT; +7/-10; CAR T-cell therapy; immunotherapy; GammaTile® ; LITT
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Molecular Mechanisms and Therapeutic Approaches for Oral Disorders
edited by , and Simona Santonocito
submission deadline 20 Aug 2025 | 6 articles | Viewed by 5779 | Submission Open
Keywords: oral diseases; drugs; local drug delivery; periodontitis; causal periodontal therapy; oral potential malignant disorders; oral cancer; oral medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
SARS-CoV-2 Infection: Focus on Pathophysiological Characteristics, Complications and Effects of Vaccinations submission deadline 31 Aug 2025 | 1 articles | Viewed by 17220 | Submission Open
Keywords: SARS-CoV-2 complications; SARS-CoV2 prognostic and predictive biomarkers; long COVID-19 and autoimmune disease; COVID-19 and microbiome; artificial intelligence
(This special issue belongs to the Section Microbiology in Human Health and Disease)
The Role of Chemerin in Human Disease2nd Edition
edited by
submission deadline 31 Aug 2025 | 7 articles | Viewed by 12790 | Submission Open
Keywords: biomarker; chemotaxis; cardiovascular diseases; cancer; chemerin isoforms; CMKLR1; GPR1; CCRL2
(This special issue belongs to the Section Cell Biology and Pathology)
From Molecules to Medicine: Deciphering Obesity and Lipid Metabolism for Translational Insights submission deadline 31 Aug 2025 | 5 articles | Viewed by 12081 | Submission Open
Keywords: obesity; insulin resistance; lipid metabolism; drug discovery
(This special issue belongs to the Section Molecular and Translational Medicine)
Antidepressants: 70 Years submission deadline 31 Aug 2025 | 4 articles | Viewed by 12067 | Submission Open
Keywords: polypharmacology; multi-target drugs; emerging therapeutic targets; repurposing; unipolar depression; bipolar disorder
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
State-of-the-Art Molecular and Translational Medicine in Poland, 3rd Edition submission deadline 31 Aug 2025 | 6 articles | Viewed by 11291 | Submission Open
Keywords: molecular medicine; molecular mechanisms; disease pathogenesis; genetic variants; gene expression; epigenetics; metabolic disorders; cancer
(This special issue belongs to the Section Molecular and Translational Medicine)
Cellular and Molecular Mechanisms in Gastrointestinal Tract Disease
edited by Felipe Leite De Oliveira
submission deadline 31 Aug 2025 | 5 articles | Viewed by 8529 | Submission Open
Keywords: cellular mechanisms; molecular mechanisms; diagnosis; treatment; experimental models; signaling pathways; comorbidities
(This special issue belongs to the Section Cell Biology and Pathology)
Inflammaging and Immunosenescence: Mechanisms and Link
edited by
submission deadline 31 Aug 2025 | 4 articles | Viewed by 8332 | Submission Open
Keywords: inflammaging; immunosenescence; autoimmune disease; age-related disease; aging
(This special issue belongs to the Section Immunology and Immunotherapy)
Compounds from Natural Products as Sources for Drug Discovery submission deadline 31 Aug 2025 | 5 articles | Viewed by 7598 | Submission Open
Keywords: natural products; drug discovery; bioactive compounds; medicinal plants; marine natural products; pharmacological screening; pharmacognosy; sustainable drug development; purification techniques; compound isolation
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Advanced Research of Stem Cells for Regenerative Medicine submission deadline 31 Aug 2025 | 2 articles | Viewed by 7339 | Submission Open
Keywords: stem cells; regenerative therapy; degenerative diseases; aging; tissue engineering
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Fabry Disease: From Molecular Insights to Innovative Therapeutics
edited by and Concetto Sessa
submission deadline 31 Aug 2025 | 6 articles | Viewed by 7050 | Submission Open
Keywords: fabry disease; lysosomal storage disorder; GLA gene mutations; enzyme replacement therapy; chaperone therapy; physical activity; imagining
(This special issue belongs to the Section Molecular and Translational Medicine)
mTOR Signaling in Disease and Therapy
edited by Wenjing Yu and
submission deadline 31 Aug 2025 | 4 articles | Viewed by 6508 | Submission Open
Keywords: mTOR signaling; tissue engineering; stem cell; disease; therapy; bone; craniofacial; biomedicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Feature Reviews in Cardiovascular Diseases submission deadline 31 Aug 2025 | 5 articles | Viewed by 6178 | Submission Open
Keywords: cardiovascular diseases; heart failure; cardiac arrhythmias; metabolic syndrome; stroke; pulmonary hypertension; peripheral artery disease (PAD); acute coronary syndrome; myocarditis; pericarditis; valvulopathies
(This special issue belongs to the Section Molecular and Translational Medicine)
High-Risk Pregnancy, Labor and Delivery submission deadline 31 Aug 2025 | 2 articles | Viewed by 5787 | Submission Open
Keywords: preterm labor; labor; delivery; pregnancy
(This special issue belongs to the Section Molecular and Translational Medicine)
Biomedical and Biochemical Basis of Neurodegenerative Diseases
edited by
submission deadline 31 Aug 2025 | 4 articles | Viewed by 5709 | Submission Open
Keywords: neurodegeneration; personalized medicine; biomarkers; diagnosis; treatment
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advances in Cancer Biology and Experimental Anticancer Therapies (2nd Edition)
edited by and
submission deadline 31 Aug 2025 | 5 articles | Viewed by 5202 | Submission Open
Keywords: cancer biology; experimental anticancer therapies; immunotherapy; immunotoxins; signalling pathways; targeted therapies
(This special issue belongs to the Section Cancer Biology and Oncology)
Advancements in Artificial Intelligence (AI) for Cancer Genomics and Genetics submission deadline 31 Aug 2025 | 3 articles | Viewed by 5022 | Submission Open
Keywords: artificial intelligence; cancer; genetics; epigenetics; genomics; epigenomics; gene-environment interaction; cancer diagnosis and prognosis; personalized medicine; drug discovery
(This special issue belongs to the Section Cancer Biology and Oncology)
Neuroendocrine Neoplasia and Endocrine Tumors: Pathogenic Features, Prognostic Markers and New Therapeutic Approaches
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 4118 | Submission Open
Keywords: neuroendocrine tumors; endocrine tumors; somatostatin analogues; carcinoid syndrome; PRRT; mTOR inhibitor; lymph node; neuroendocrine marker; hormone; ki67
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Digestive Disorders: Translation and Bridging the Gap Between Research, Diagnosis, and Treatment
edited by Goran Hauser and Goran Poropat
submission deadline 31 Aug 2025 | 5 articles | Viewed by 3932 | Submission Open
Keywords: acute pancreatis; clinical nutrition; metabolic disorders; NAFLD; obesity; DGBA; gut microbiota
(This special issue belongs to the Section Molecular and Translational Medicine)
Role of Bone Marrow Niche in Haematological Cancers submission deadline 31 Aug 2025 | 2 articles | Viewed by 3857 | Submission Open
Keywords: blood cancers; bone marrow; microenvironment; immune stromal interactions; mesenchymal stem cells
(This special issue belongs to the Section Cancer Biology and Oncology)
Natural Product for the Interventions of Chronic Diseases: From Source to Therapy
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 3668 | Submission Open
Keywords: natural products; chronic diseases; drug discovery; pharmacodynamics; pharmacokinetics; nanotechnology
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Bioactive Peptides and Derivatives as Therapeutic Agents: Potential Applications in Disease Treatment
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 3432 | Submission Open
Keywords: bioactive peptide; peptide modification; application; cardiovascular disease; inflammatory disease; digestive disease; neurological disease; drug development
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Mitochondrial Dysfunction and Oxidative Stress
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 3197 | Submission Open
Keywords: mitochondria; oxidative stress; brain metabolism; neurodevelopmental diseases; neuropsychiatric diseases; neurodegenerative diseases; mitochondrial medicine; translational medicine
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Mechanisms and Novel Therapeutic Approaches for Neurodegenerative Diseases (2nd Edition)
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 3166 | Submission Open
Keywords: neurodegenerative diseases; cellular mechanisms; molecular mechanisms; neurodegeneration models; protein misfolding; protein aggregation; neuronal death; molecular therapy; cellular therapy; therapeutics; medical chemistry; drug screening
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Adiposity, Inflammation, and Metabolic Regulation: Molecular Mechanisms and Therapeutic Strategies
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 2920 | Submission Open
Keywords: adipose tissue; inflammation; obesity and its metabolic complications; obesity pathogenesis
(This special issue belongs to the Section Molecular and Translational Medicine)
MicroRNAs as Mediators of Tumor Cell State Transitions, Receptor Remodeling, Drug Resistance, and Systemic Metastasis
edited by and Michael J. Kerin
submission deadline 31 Aug 2025 | 1 articles | Viewed by 2774 | Submission Open
Keywords: solid epithelial tumors; cancer stem cells; microRNAs; epigenetics; cell state transitions; chemoresistance; immunosuppression; tumor microenvironment; metastasis
(This special issue belongs to the Section Cancer Biology and Oncology)
Progress in Cardiovascular Pharmacology submission deadline 31 Aug 2025 | 1 articles | Viewed by 2668 | Submission Open
Keywords: cardiovascular diseases; cardiovascular pharmacology; target therapies; molecular pharmacology; heart failure; preventive cardiology; atherosclerosis
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Connective Tissue Disorders: Pathogenetic, Diagnostic and Therapeutic Perspectives submission deadline 31 Aug 2025 | 3 articles | Viewed by 2631 | Submission Open
Keywords: connective tissue disorders; pathophysiological mechanisms; inflammation; autoimmunity; extracellular matrix; fibrosis; biomarkers; treatment; therapeutic targets
(This special issue belongs to the Section Molecular and Translational Medicine)
Platelets in Health and Disease: From Molecular Mechanisms to Therapeutic Potential
edited by Henry Nording
submission deadline 31 Aug 2025 | 2 articles | Viewed by 2592 | Submission Open
Keywords: platelet biology; vascular immunity; atherosclerosis; therapeutic targets; biomarkers
(This special issue belongs to the Section Cell Biology and Pathology)
Advances in Liquid Biopsy from Technological Innovation to Therapeutic Intervention
edited by and
submission deadline 31 Aug 2025 | 2 articles | Viewed by 2159 | Submission Open
Keywords: liquid biopsy; biomarkers; circulating tumor cells
(This special issue belongs to the Section Molecular and Translational Medicine)
Animal Models for the Study of Human Diseases
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 2104 | Submission Open
Keywords: animal models; zebrafish; mice; rats
(This special issue belongs to the Section Molecular and Translational Medicine)
Advancements in Induced Pluripotent Stem Cells
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1944 | Submission Open
Keywords: induced pluripotent stem cells; organoids; tissue engineering; biomaterials; reprogramming; iPSC-based cell modelling; cell therapy; microfluidics; drug discovery
(This special issue belongs to the Section Gene and Cell Therapy)
Drug Resistance and Tumor Microenvironment in Human Cancers
edited by , and Marília Isabel Neto Figueira
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1869 | Submission Open
Keywords: cancer therapy; drug resistance; tumor microenvironment; targeted therapy; precision medicine; cancer-related mechanisms
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Pediatric Ocular Pathology and Treatment
edited by Hyun-jin Shin
submission deadline 31 Aug 2025 | 2 articles | Viewed by 1710 | Submission Open
Keywords: pediatric ophthalmology; eye diseases; genetics; medical; diagnostic techniques; ophthalmological; therapeutics
(This special issue belongs to the Section Cell Biology and Pathology)
Advanced Research on Skeletal Muscle Metabolism
edited by Lorenzo Sanesi
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1688 | Submission Open
Keywords: energy metabolism; mebabolic signaling pathways; homeostasis; myokines; aging; atrophy; muscle metabolism
(This special issue belongs to the Section Molecular and Translational Medicine)
Biotechnology in the Treatment and Management of Hearing Loss submission deadline 31 Aug 2025 | 1 articles | Viewed by 1664 | Submission Open
Keywords: hearing loss; gene therapy; regenerative medicine; cochlear implants; nanotechnology stem cell therapy; CRISPR-Cas9; auditory prosthetics; artificial intelligence; auditory regeneration
(This special issue belongs to the Section Biomedical Engineering and Materials)
Advancements in Brain Diagnosis and Treatment: From Insights to Innovations
edited by Irene Chaves-Coira and
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1636 | Submission Open
Keywords: brain diagnosis and treatment; underlying mechanisms; individualized treatment
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
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