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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular and Cellular Mechanisms of Cardiovascular Diseases: 2nd Edition

edited by

Antonella Galeone

submission deadline 30 Sep 2025 | Viewed by 114 | Submission Open

Keywords: hypertension; diabetes; coronary heart disease; valvular heart disease; infective endocarditis; aortic dissection; aortic aneurysm; heart failure; cardiomyopathy

(This special issue belongs to the Section Molecular and Translational Medicine)

Oxidative Stress, Inflammation and Endothelial Dysfunction in COVID-19 Era and Long COVID-19 Complications

edited by

Ekaterina Georgieva

submission deadline 30 Sep 2025 | Viewed by 114 | Submission Open

Keywords: oxidative stress; redox-disbalance; COVID-19; post-COVID-19; cytokines; mitochondrial dysfunction; endothelial damages; ROS and RNS; thrombosis; antioxidant therapy; oxidative shock

(This special issue belongs to the Section Molecular and Translational Medicine)

Unveiling the Genetic Architecture of Complex and Common Diseases

edited by

Mahmut Cerkez Ergoren

submission deadline 30 Sep 2025 | Viewed by 109 | Submission Open

Keywords: polygenetic score; cardiovascular disorders; metabolic disorders; neurodegenerative disorders

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Skin Diseases and Cell Therapy

edited by Nives Pondeljak, Maryam Heidari Kharaji and Mirna Šitum

submission deadline 30 Sep 2025 | Viewed by 108 | Submission Open

Keywords: dermatology; psoriasis; atopic dermatitis; vitiligo; alopecia; cutaneous leishmaniasis; and skin fibrosis; skin cancers; innovative therapeutic strategies; molecular mechanisms

(This special issue belongs to the Section Gene and Cell Therapy)

Recent Advances in Endothelial Dysfunction

edited by

Manfredi Tesauro

submission deadline 30 Sep 2025 | Viewed by 101 | Submission Open

Keywords: endothelial dysfunction; atherosclerosis; nitric oxide (NO); hyperlipidemia; hypertension; hyperglycemia; vasodilation; perivascular adipose tissue (PVAT); insulin resistance

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Recent Advances in Molecular Neuroimaging

edited by

Wenliang Fan

submission deadline 30 Sep 2025 | Viewed by 99 | Submission Open

Keywords: molecular neuroimaging; imaging techniques; clinical applications; imaging probes; personalized medicine; diagnostic imaging; therapeutic monitoring; clinical decision support

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Extracellular Vesicles in Therapeutics

edited by

Mangesh D. Hade

and

Akil Akhtar

submission deadline 30 Sep 2025 | Viewed by 98 | Submission Open

Keywords: extracellular vesicles (EVs); exosomes; regenerative medicine; immunotherapy; nanocarriers; biomarkers

(This special issue belongs to the Section Immunology and Immunotherapy)

Pathogenesis and Targeted Therapy of Autoimmune Diseases

edited by

Marcella Prete

submission deadline 30 Sep 2025 | Viewed by 98 | Submission Open

Keywords: autoimmune diseases; pathogenesis; targeted therapy

(This special issue belongs to the Section Molecular and Translational Medicine)

Artificial Intelligence Applications in Cancer and Other Diseases—2nd Edition

edited by

Raji Sundararajan

submission deadline 30 Sep 2025 | Viewed by 96 | Submission Open

Keywords: artificial intelligence; machine learning; neural networks; deep learning; obesity; diabetes; cancer; other diseases; pathology; drug discovery

(This special issue belongs to the Section Biomedical Engineering and Materials)

Intracellular Optogenetics Tools to Probe Biological Signaling Pathways

edited by

Qunxiang Ong

submission deadline 30 Sep 2025 | Viewed by 94 | Submission Open

Keywords: optogenetics; signaling transduction; neuroscience; immunology; cancer signaling; synthetic biology; spatiotemporal resolution

(This special issue belongs to the Section Molecular and Translational Medicine)

Matrix Biology Insights: Unraveling the Role of Proteinases, Fibroblasts, and Extracellular Matrix Metalloproteinase Inducer in the Tumor Microenvironment

edited by

Eric Huet

submission deadline 30 Sep 2025 | Viewed by 92 | Submission Open

Keywords: tumor microenvironment; proteinases; fibroblasts; EMMPRIN; matrix biology; extracellular matrix (ECM); matrix metalloproteinases (MMPs)

(This special issue belongs to the Section Cancer Biology and Oncology)

Biomaterials for Bone Regeneration: 2nd Edition

edited by

Kyeong-Hyeon Park

submission deadline 30 Sep 2025 | Viewed by 91 | Submission Open

Keywords: bone regeneration; bone defect; induced membrane technique; bone transport; biomaterials

(This special issue belongs to the Section Biomedical Engineering and Materials)

Interdisciplinary Perspectives on Protein Glycosylation, Signaling, and Toxicity in Biological Systems

edited by Ashutosh Pandey

submission deadline 30 Sep 2025 | Viewed by 89 | Submission Open

Keywords: glycosylation; signaling pathways; toxicity; environmental chemicals; animal models

(This special issue belongs to the Section Cell Biology and Pathology)

Recent Advances in Obesity-Related Metabolic Diseases: 2nd Edition

edited by Sandip Mukherjee

submission deadline 30 Sep 2025 | Viewed by 89 | Submission Open

Keywords: obesity; metabolism; adipose tissue; liver inflammation; hyperglycemia; hyperlipidemia; cardiovascular diseases; new drug targets; translational studies

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Innovations and Perspectives in Kidney Transplantation

edited by Vassilis Filiopoulos

submission deadline 30 Sep 2025 | Viewed by 87 | Submission Open

Keywords: bioartificial kidney; immunology; immunosuppression; kidney transplantation; tolerance; graft rejection; graft survival; xenotransplantation; kidney regeneration

(This special issue belongs to the Section Immunology and Immunotherapy)

New Advances in the Pathology, Diagnosis and Treatment of Thyroid Tumors

edited by

Przemyslaw Zdziarski

submission deadline 30 Sep 2025 | Viewed by 75 | Submission Open

Keywords: goitre; thyroid cancer; screening; bias; paraneoplastic syndrome ; immunosurveillance ; thyroiditis ; thyroidectomy ; immunotherapy

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Diagnostic and Therapeutic Approaches to Pancreatic Cancer—Second Edition

edited by

Sanchita Rauth

submission deadline 30 Sep 2025 | Viewed by 73 | Submission Open

Keywords: pancreatic cancer; systemic therapy; immunotherapy; tumor microenvironment; biomarkers

(This special issue belongs to the Section Cancer Biology and Oncology)

Neuromuscular Diseases: Biochemical, Genetic, and Electrophysiological Studies

edited by

Vincenzo Macaione

submission deadline 30 Sep 2025 | Viewed by 71 | Submission Open

Keywords: neuromuscular disorders; motor neuron diseases; myopathies; neuropathies; autoimmune neuromuscular diseases; electromyography; nerve conduction studies; epigenomics; genomics; new therapeutic approaches; myasthenia; mitochondrial disease

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Molecular Cytogenetics in Health and Diseases

edited by

Rong Xiang

submission deadline 30 Oct 2025 | Viewed by 57 | Submission Open

Keywords: genetic mutations; high-throughput sequencing; genomics; multiomics; rare diseases

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Pathological Biomarkers in Precision Medicine

edited by

Ovidiu Constantin Baltatu

, Mirela A. Dobre and Tudor Groza

submission deadline 31 Oct 2025 | 6 articles | Viewed by 13582 | Submission Open

Keywords: pathological biomarkers; precision medicine; artificial intelligence; medical imaging; omics data analysis; personalized medicine; biomarker discovery; digital pathology

(This special issue belongs to the Section Cell Biology and Pathology)

Breast Cancer: New Diagnostic and Therapeutic Approaches

edited by

Erika Bandini

Tania Rossi

and Sara Bravaccini

submission deadline 31 Oct 2025 | 8 articles | Viewed by 12814 | Submission Open

Keywords: breast cancer; breast oncology; circulating tumor cells

(This special issue belongs to the Section Cancer Biology and Oncology)

Mechanisms and Pharmacological Targets for Pain

edited by Renan F. do Espírito-Santo

submission deadline 31 Oct 2025 | 4 articles | Viewed by 7810 | Submission Open

Keywords: drug discovery; chronic pain; inflammatory pain; mechanisms of action; pain pharmacology; immunomodulation; neuropathic pain

(This special issue belongs to the Section Molecular and Translational Medicine)

Emerging Issues in Retinal Degeneration

edited by

Ponarulselvam Sekar

submission deadline 31 Oct 2025 | 5 articles | Viewed by 7178 | Submission Open

Keywords: retinal degeneration; age-related macular degeneration (AMD); retinitis pigmentosa (RP); diabetic retinopathy; gene therapy; stem cell therapy; retinal implants; pharmacological treatments; diagnostic methods; molecular mechanisms; predictive biomarkers; imaging technologies; signaling pathways; oxidative stress; neuroprotection

(This special issue belongs to the Section Cell Biology and Pathology)

Advances in Fetal Medicine and Neonatology

edited by

Robert Brawura-Biskupski-Samaha

submission deadline 31 Oct 2025 | 4 articles | Viewed by 6752 | Submission Open

Keywords: fetal medicine; neonatology; research innovations; perinatal care; clinical practices

(This special issue belongs to the Section Molecular and Translational Medicine)

Feature Reviews in Gastrointestinal Diseases

edited by

Fu-Chen Huang

submission deadline 31 Oct 2025 | 5 articles | Viewed by 5961 | Submission Open

Keywords: precision medicine; artificial intelligence; eosinophilic gastrointestinal diseases; inflammatory bowel disease; irritable bowel syndrome; gastroesophageal reflux disease; gastrointestinal cancers; drug-resistant infections

(This special issue belongs to the Section Molecular and Translational Medicine)

Genetic Research on Neuropsychiatric Disorders and Complex Human Diseases

edited by Wen Zhang

submission deadline 31 Oct 2025 | 5 articles | Viewed by 5631 | Submission Open

Keywords: neuropsychiatric disorders; complex human diseases; genetic research; omics data analysis; high-throughput sequencing; machine learning; disease mechanism

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Mechanisms of Steroid Hormone Action—2nd Edition

edited by

Omar Cauli

submission deadline 31 Oct 2025 | 3 articles | Viewed by 5217 | Submission Open

Keywords: oestrogen; androgens; thyroid; adrenal gland; menopause; cancer

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Pathogenesis, Diagnostics, and Therapeutics for Rheumatic Diseases

edited by Jixin Zhong

submission deadline 31 Oct 2025 | 8 articles | Viewed by 4966 | Submission Open

Keywords: rheumatic diseases; pathogenesis; autoimmunity; biomarkers; precision medicine; therapeutics; disease management; immunology; clinical diagnostics; treatment strategies

(This special issue belongs to the Section Molecular and Translational Medicine)

Advanced Research in Hypertrophic Cardiomyopathy

edited by Said Alsidawi,

Juan Farina

and

Celestino Sardu

submission deadline 31 Oct 2025 | 6 articles | Viewed by 4817 | Submission Open

Keywords: hypertrophic cardiomyopathy; myosin inhibitors; genetic therapy; risk stratification

(This special issue belongs to the Section Molecular and Translational Medicine)

Innovative Approaches to Molecular Pathogenesis and Therapy of Lymphoid Malignancies

edited by

Dalia El-Gamal

and

Audrey Smith

submission deadline 31 Oct 2025 | 5 articles | Viewed by 4420 | Submission Open

Keywords: lymphoma; leukemia; myeloma; lymphoproliferative disorders; B-cell neoplasms; T-cell neoplasms; pathogenesis; molecular targets; novel therapies; translational research; tumor microenvironment

(This special issue belongs to the Section Cell Biology and Pathology)

Advanced Research in Atrial Fibrillation

edited by

Wern Yew Ding

submission deadline 31 Oct 2025 | 4 articles | Viewed by 4353 | Submission Open

Keywords: atrial fibrillation; arrhythmia; electrophysiology; cardiovascular; mechanism; laboratory; experimental

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Research in Obesity, 2nd Edition

edited by Zaida Abad-Jiménez and

Teresa Vezza

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3937 | Submission Open

Keywords: obesity; genetics; molecular pathways; adipose tissue; metabolism; leukocytes; prevention; new targets for treatment; translational studies

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Pathogenesis and Novel Therapeutics in Musculoskeletal Conditions, 3rd Edition

edited by

Juan Antonio Valera-Calero

and

Gustavo Plaza-Manzano

submission deadline 31 Oct 2025 | 3 articles | Viewed by 3859 | Submission Open

Keywords: neck pain; low back pain; myofascial pain syndromes; chronic pain; musculoskeletal disorders; disability; pain treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Head and Neck Tumors, 4th Edition

edited by

Silvia Di Agostino

and

Jan B. Vermorken

submission deadline 31 Oct 2025 | 4 articles | Viewed by 3624 | Submission Open

Keywords: head and neck tumors; predictive markers; liquid biopsy; therapy; precision medicine; biomaterials

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Novel Drug Discovery, Synthesis, and Evaluation

edited by

Khaled M. Elokely

submission deadline 31 Oct 2025 | 1 articles | Viewed by 3582 | Submission Open

Keywords: drug synthesis; novel therapies; disease targets; medicinal chemistry; computational methods; screening techniques; pharmaceutical development; target identification

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Gynecological Diseases in Cellular and Molecular Perspectives

edited by

Iwona Wertel

and

Anna Pawłowska-Łachut

submission deadline 31 Oct 2025 | 3 articles | Viewed by 3171 | Submission Open

Keywords: gynaecological diseases; endometriosis; biomarkers; immune checkpoints; immunotherapy; tumor microenvironment; tumor-infiltrating immune cells; cancer immunology; cellular interactions

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Pathogenesis and Therapeutics of Gastrointestinal Diseases

edited by

Jinghua Wang

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3088 | Submission Open

Keywords: gastrointestinal diseases; IBD; IBS; GERD; functional dyspepsia; gut microbiome

(This special issue belongs to the Section Molecular and Translational Medicine)

Pathogenesis, Diagnosis, and Treatment of Respiratory Diseases

edited by

Te-Chun Shen

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3044 | Submission Open

Keywords: COPD; asthma; interstitial lung disease; lung cancer; pneumonia; tuberculosis; respiratory failure; ARDS; COVID-19; obstructive sleep apnea

(This special issue belongs to the Section Cell Biology and Pathology)

Epigenetic Regulation and Its Impact for Medicine (2nd Edition)

edited by

Marie Černá

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2946 | Submission Open

Keywords: gene expression; DNA methylation; histone modifications; non-coding RNAs; biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Maternal-Fetal and Neonatal Medicine

edited by

Dimitrios Papageorgiou

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2849 | Submission Open

Keywords: maternal– fetal health; neonatal health; prenatal care; prenatal diagnosis; fetal growth; diabetes mellitus; hypertension; pre-eclampsia; congenital infections; gene therapies

(This special issue belongs to the Section Molecular and Translational Medicine)

Feature Reviews in Tumor Immunology

edited by

Maria-Ioanna Christodoulou

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2756 | Submission Open

Keywords: tumor immunity; immunotherapy; engineered immune cells; antibodies; immunomodulators; cytokines; survival; immune-checkpoint inhibitors; tumor immune microenvironment

(This special issue belongs to the Section Immunology and Immunotherapy)

Cell Signaling and Molecular Regulation in Neurodegenerative Disease

edited by Shao-Ming Wang

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2681 | Submission Open

Keywords: neurological diseases; gene regulation; molecular neurobiology; neurodegenerative disease

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Dualistic Equilibrium in Neurotransmission and Beyond: Unraveling the Pathophysiology and Unlocking Novel Therapeutic Targets in Neuropsychiatric Disorders—2nd Edition

edited by

Masaru Tanaka

and

Simone Battaglia

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2517 | Submission Open

Keywords: Alzheimer’ s disease; Parkinson’ s disease; cognitive dysfunction; multiple sclerosis; stroke; migraine; chronic pain; depressive disorder; bipolar disorder; post-traumatic stress disorder; anxiety disorder; schizophrenia; somatic symptom disorder; autism spectrum disorder; hyperactive attention deficit disorder; learning disabilities; brain injuries; comorbidity; brain plasticity; transcranial magnetic stimulation (TMS); transcranial direct current stimulation (tDCS)

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Trends in 3D Printing Processes for Biomedical Field: Opportunities and Challenges (2nd Edition)

edited by

M. R. Mozafari

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2397 | Submission Open

Keywords: 3D/4D bioprinting techniques; 3D bioprinting processes; 3D cellular microenvironment; bio-inks; hydrogels

(This special issue belongs to the Section Biomedical Engineering and Materials)

Innovative Approaches in In Vitro Skin Models: From Design to Application

edited by

Tina Maver

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2326 | Submission Open

Keywords: in vitro skin models; tissue engineering; dermatological research; 3D skin bioprinting; skin disease modeling

(This special issue belongs to the Section Biomedical Engineering and Materials)

Sphingolipid Metabolism and Signaling in Health and Diseases: 2nd Edition

edited by

Giulia Lunghi

Elena Chiricozzi

and

Maria Fazzari

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2274 | Submission Open

Keywords: sphingolipids; glycosphingolipids; gangliosides; sphingosine-1-phosphate; cell homeostasis; neurodegeneration; neurodevelopment; inflammation; diabetes; cystic fibrosis; cancer

(This special issue belongs to the Section Cell Biology and Pathology)

Oxidative Stress and Inflammation: From Mechanisms to Therapeutic Approaches (4th Edition)

edited by

Juan Gambini

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2226 | Submission Open

Keywords: oxidative stress; inflammation; molecular mechanisms; pharmacotherapy; longevity; aging

(This special issue belongs to the Section Immunology and Immunotherapy)

Recent Developments in Mycobacterial Research

edited by

Vishwanath Venketaraman

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2021 | Submission Open

Keywords: Mycobacterium tuberculosis; mycobacterial; host immune responses

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Musculoskeletal Diseases: From Molecular Basis to Therapy—3rd Edition

edited by

Elisa Belluzzi

and

Assunta Pozzuoli

submission deadline 31 Oct 2025 | 3 articles | Viewed by 1937 | Submission Open

Keywords: musculoskeletal diseases; bone cancer; soft tissue cancer; bone metastasis; natural compounds; anticancer drugs; osteoarthritis; joint tissues; biomarkers; inflammation; microRNAs; exosomes

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Liver Oncology: Molecular Mechanisms and Therapeutic Innovations

edited by

Rui Caetano Oliveira

, Rui Miguel Martins and

José Guilherme Tralhão

submission deadline 31 Oct 2025 | 3 articles | Viewed by 1932 | Submission Open

Keywords: liver cancer; hepatocellular carcinoma; cholangiocarcinoma; liver metastases; tumor microenvironment; targeted therapy; immunotherapy; biomarkers; drug resistance

(This special issue belongs to the Section Cancer Biology and Oncology)

Displaying special issue 251-300 on page 6 of 15.

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