Adult Congenital Heart Disease: Diagnosis, Treatment and Prognosis

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 635

Special Issue Editor


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Dipartimento di Scienze Cardiologiche, Toraciche e Vascolari Università degli Studi di Padova, Via A. Gabelli, 61, 35121 Padova, Italy
Interests: cardiovascular pathology; cardiology; cardiac surgery; genetic; sudden death; cardiomyopathies
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Dear Colleagues,

Congenital heart defects (structural abnormalities present at birth) may remain concealed until adulthood, posing a treat in the long term on health, life quality and longevity.

This Special Issue focuses on the recent progress in early diagnosis, management by drug therapy, interventional cardiology and surgery and heart transplantation. Complications like endocarditis, congestive heart failure, thrombosis and Eisenmenger's syndrome will also be addressed.

Dr. Gaetano Thiene
Guest Editor

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Keywords

  • adult congenital heart disease
  • eisenmenger's syndrome
  • endocarditis
  • thromboprophylaxis

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Published Papers (1 paper)

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17 pages, 49924 KiB  
Perspective
Congenital Heart Disease from Infancy to Adulthood: Pathology and Nosology
by Gaetano Thiene and Marny Fedrigo
Biomedicines 2025, 13(4), 875; https://doi.org/10.3390/biomedicines13040875 - 4 Apr 2025
Viewed by 366
Abstract
Congenital heart diseases (CHDs) are usually defined as structural anomalies of the heart and great arteries, present since birth, that are due to embryological maldevelopment, with overt or potential dysfunction. Nowadays, most of the patients with CHD in adulthood (age > 18 years) [...] Read more.
Congenital heart diseases (CHDs) are usually defined as structural anomalies of the heart and great arteries, present since birth, that are due to embryological maldevelopment, with overt or potential dysfunction. Nowadays, most of the patients with CHD in adulthood (age > 18 years) had been operated on with success in infancy or childhood and undergo periodical screening. Pathology and nosology of CHDs are herein treated with special attention to adulthood according to the involved cardiac structures (aorta, valves, coronary arteries, myocardium, great arteries, conduction system). Moreover, the purpose is to postulate, in the era of molecular medicine, that genetically determined defects are also congenital cardiac disorders, with or without structural abnormality, and should be defined CHDs as well since their molecular background is material and present since conception. Full article
(This article belongs to the Special Issue Adult Congenital Heart Disease: Diagnosis, Treatment and Prognosis)
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