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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Insights in Hematologic Malignancies: From Pathophysiologic Mechanisms to Therapeutic Strategies

edited by

Yun Chen

submission deadline 31 Dec 2025 | Viewed by 86 | Submission Open

Keywords: leukemia; hematological malignancies; tumor microenvironment; disease models; precision medicine; immunotherapy; targeted therapy; drug resistance; biomarkers; translational research

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Hematological Malignancies: Diagnostic Strategies, Molecular Mechanisms, Prognostic Markers and Therapeutic Approaches

edited by José Antonio García-Vela and Fernando Martin-Moro

submission deadline 31 Dec 2025 | Viewed by 82 | Submission Open

Keywords: hematological malignancies; diagnostic strategies; hematopathology; flow cytometry; molecular biology; prognostic markers; targeted therapies; immunotherapy; cellular therapy

(This special issue belongs to the Section Molecular and Translational Medicine)

NASH and Hepatocellular Carcinoma (HCC)—2nd Edition

edited by

Feng He

Ruirui Wang

and Xin Yang

submission deadline 31 Dec 2025 | Viewed by 81 | Submission Open

Keywords: NAFLD; NASH; HCC; obesity; inflammation; immunotherapy; stress

(This special issue belongs to the Section Cancer Biology and Oncology)

Diagnosis, Pathogenesis and Treatment of CNS Tumors (2nd Edition)

edited by

Dimitrios Kanakis

submission deadline 31 Dec 2025 | Viewed by 48 | Submission Open

Keywords: CNS tumors; diagnosis; pathogenesis; treatment; prognosis; molecular markers

(This special issue belongs to the Section Molecular and Translational Medicine)

Gene- and Peptide-Based Therapeutics for Neurodegenerative Disorders

edited by

Ramona Meanti

and Chiara Lucchi

submission deadline 31 Dec 2025 | Viewed by 40 | Submission Open

Keywords: neurodegenerative diseases; gene therapy; peptide-based therapeutics; targeted drug delivery; neuroprotection

New Insights in Respiratory Diseases

edited by

Diego Bagnasco

submission deadline 31 Dec 2025 | Viewed by 40 | Submission Open

Keywords: asthma; COPD; bronchiectasis; genetic; therapeutics

(This special issue belongs to the Section Molecular and Translational Medicine)

Omics Approaches on Immune-Mediated Inflammatory Diseases: Towards Novel Biomarkers and Potential Therapeutic Targets, 3rd Edition

edited by

Maria-Ioanna Christodoulou

submission deadline 31 Dec 2025 | Viewed by 38 | Submission Open

Keywords: IMIDs; IBD; Crohn’ s disease; ulcerative colitis; SLE; Sjogren’ s syndrome; rheumatoid arthritis; psoriatic arthritis; multiple sclerosis; bulk and single-cell omics; multi-omics flow cytometry; next-generation microscopy; tissue microarrays; systems biology

(This special issue belongs to the Section Immunology and Immunotherapy)

Three-Dimensional Printed Meshes in Guided Bone Regeneration

edited by

Giulia Guarnieri

Annamaria Morelli

and

Claudio Cirrincione

submission deadline 31 Dec 2025 | Viewed by 33 | Submission Open

Keywords: 3D– 4D printing; vascular metabolism; mucosal stiffness; bone and gingival cells metabolism; bioprinting; melt electrowriting; shape-memory materials; titanium and polycaprolactone meshes

(This special issue belongs to the Section Biomedical Engineering and Materials)

Exploring Neuroinflammation in Central and Peripheral Neuropathic Pain and Related Disorders

edited by

Tahmineh Mokhtari

submission deadline 31 Dec 2025 | Viewed by 32 | Submission Open

Keywords: neuroinflammation; neuropathic pain; central nervous system; peripheral nervous system; affective disorders; cognitive disorders; in silico modeling; in vitro assays; in vivo models; medical and non-pharmacological interventions

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Current Perspectives on Gynecologic Cancers

edited by

Kecheng Huang

submission deadline 31 Dec 2025 | Viewed by 30 | Submission Open

Keywords: gynecology; genetics; biology; bioinformatics; review; predictive model; artificial intelligence

(This special issue belongs to the Section Cancer Biology and Oncology)

Advanced Research on Diabetic Retinopathy

edited by Stamatios Lampsas

submission deadline 31 Dec 2025 | Viewed by 26 | Submission Open

Keywords: diebetic retinopathy; retinal diseases; novel treatment strategies; progression; pathogenetic mechanisms; non-proliferative diabetic retinopathy; proliferative diabetic retinopathy

(This special issue belongs to the Section Molecular and Translational Medicine)

Mechanism of Mesenchymal Stromal Cells and Their Derivatives in Regenerative Medicine

edited by Jia Xian Law and

Kok Lun Pang

submission deadline 31 Dec 2025 | Viewed by 23 | Submission Open

Keywords: mesenchymal stromal cell; regenerative medicine; stem cell; extracellular vesicle; mechanism of action; paracrine factor; secretome; tissue engineering

(This special issue belongs to the Section Biomedical Engineering and Materials)

Advancements and Innovations in Chemotherapy

edited by

Yu-Jung Lin

submission deadline 31 Dec 2025 | Viewed by 18 | Submission Open

Keywords: chemotherapy; drug resistance; immunotherapy; combination therapy; drug delivery systems; novel agents; personalized medicine; tumor microenvironment

(This special issue belongs to the Section Cell Biology and Pathology)

Pharmacogenomics and Drug Metabolism: From Cytochrome P450 to Emerging Enzymatic Pathways

edited by

Pradeepraj Durairaj

submission deadline 31 Dec 2025 | Viewed by 16 | Submission Open

Keywords: cytochrome P450 (CYP450); drug metabolism; xenobiotic metabolism; pharmacogenomics; biotransformation; orphan enzymes; redox biology; enzyme engineering; multi-omics approaches; personalized medicine

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Breast Cancer Research: Charting Future Directions

edited by

Mohamad Adam Bujang

submission deadline 31 Dec 2025 | Viewed by 15 | Submission Open

Keywords: personalized medicine; biomarkers for early detection; immunotherapy; patient-reported outcomes

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Chondrocyte Biology (2nd Edition)

edited by

Bo Qiu

submission deadline 31 Dec 2025 | Viewed by 14 | Submission Open

Keywords: osteoarthritis; chondrocyte; differentiation; proliferation; signaling pathways; transcription factor; inflammation; cellular processes; cartilage repair

(This special issue belongs to the Section Cell Biology and Pathology)

Pathomechanisms of Disturbances Underlying Chronic Disorders—Third Edition

edited by

Dorota Formanowicz

submission deadline 31 Dec 2025 | Viewed by 11 | Submission Open

Keywords: chronic disorders; atherosclerosis; inflammation; oxidative stress; lipoproteins; endothelial dysfunction; biomarkers; pathomechanisms

(This special issue belongs to the Section Immunology and Immunotherapy)

Genetic Research on Colorectal Cancers

edited by

Wangxiong Hu

submission deadline 31 Dec 2025 | Viewed by 10 | Submission Open

Keywords: high microsatellite instability; epigenetic age acceleration; spatial omics and single-cell sequencing; cold tumors and immunotherapy; driver gene; DNA replication repair; liquid biopsy; ctDNA

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Precision Oncology for Thyroid Carcinoma: Integrating Artificial Intelligence, Genomics and Molecular Diagnostics

edited by

Kyoung Sik Park

submission deadline 31 Dec 2025 | Viewed by 10 | Submission Open

Keywords: thyroid carcinoma; artificial intelligence; genomics; precision oncology; molecular diagnostics

(This special issue belongs to the Section Cancer Biology and Oncology)

Epigenetics in Human Cancer: Emerging Biomarkers and Therapeutic Targets

edited by

Jeong-yeon Lee

submission deadline 31 Dec 2025 | Viewed by 10 | Submission Open

Keywords: cancer; epigenetics; DNA methylation; histone modification; chromatin remodeling; non-coding RNAs; therapeutic resistance

(This special issue belongs to the Section Cancer Biology and Oncology)

Animal Models for the Study of Cardiovascular Physiology—Second Edition

edited by Sandra Lia Amaral

submission deadline 31 Dec 2025 | Viewed by 9 | Submission Open

Keywords: hypertension; stroke; myocardium infarction; arterial stiffness; supravalvular aortic stenosis; cardiac remodeling; capillary angiogenesis; exercise training; vascular diseases; non-pharmacological treatment

(This special issue belongs to the Section Cell Biology and Pathology)

The Role of Telomere and Telomerase in Human Disease-2nd Edition

edited by

Orit Uziel

submission deadline 31 Dec 2025 | Viewed by 9 | Submission Open

Keywords: telomere; telomerase; cancer; aging

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Heart–Brain Axis

edited by Teresa Soda

submission deadline 31 Dec 2025 | Viewed by 8 | Submission Open

Keywords: heart– brain axis; neurocardiology; autonomic nervous system; neuroinflammation; cardiac– cerebral syndromes; psychocardiology; calcium signaling; synaptic plasticity; ion transport; translational neuroscience

(This special issue belongs to the Section Molecular and Translational Medicine)

Glomerular Disease and Cystic Kidney Disease: From Pathogenesis to Novel Therapeutic Approaches—2nd Edition

edited by Vassilis Filiopoulos and

Chrysanthi Skalioti

submission deadline 31 Dec 2025 | Viewed by 8 | Submission Open

Keywords: glomerular disease; glomerulonephritis; glomerulopathy; podocytopathies; ciliopathies; cystic kidney disease; polycystic kidney disease; tolvaptan; vasopressin

(This special issue belongs to the Section Molecular and Translational Medicine)

Dopamine and Androgen Receptor Signaling: Novel Insights in Cancer Biology

edited by Srijan Acharya

submission deadline 31 Dec 2025 | Viewed by 8 | Submission Open

Keywords: dopamine signaling; androgen receptor; cancer biology; hormone-sensitive tumors; signal transduction; tumor microenvironment; neurotransmitters in cancer; prostate cancer; breast cancer; targeted therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Oxidative Stress in Health and Disease

edited by Federica Mannino

submission deadline 31 Dec 2025 | Viewed by 7 | Submission Open

Keywords: oxidative stress; inflammation; human diseases; apoptosis; peroxidation; DNA damage; mitochondria

(This special issue belongs to the Section Cell Biology and Pathology)

HIV Therapy: The Latest Developments in Antiviral Drugs

edited by

Francisco Javier Fanjul Losa

submission deadline 31 Dec 2025 | Viewed by 7 | Submission Open

Keywords: HIV; antiviral drugs; experimental therapeutics; drug discovery; viral reservoirs; mechanism of action; preclinical models; novel HIV targets; antiretroviral therapy (ART); immunotherapy (experimental aspects)

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Recent Advances in Gastrointestinal Cancers: From Microbiota Modulation to New Therapeutic Approaches—2nd Edition

edited by

Serena Martinelli

submission deadline 31 Dec 2025 | Viewed by 6 | Submission Open

Keywords: gastrointestinal cancers; microbiota; anticancer therapy; immunotherapy; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

Oral Squamous Cell Carcinoma: Molecular Signaling Pathways and Novel Biomarkers—2nd Edition

edited by

Sadhna Aggarwal

submission deadline 31 Dec 2025 | Viewed by 5 | Submission Open

Keywords: oral squamous cell carcinoma (OSCC); molecular signaling pathways; biomarkers; pathogenesis; targeted therap; tumor growth; tumor invasion; angiogenesis; tumor metastasis; immune response modulation

(This special issue belongs to the Section Cancer Biology and Oncology)

Novel Drug Delivery Systems: Design, Evaluation and Application: 2nd Edition

edited by

Yongtai Zhang

submission deadline 31 Dec 2025 | Viewed by 4 | Submission Open

Keywords: pharmaceutics; drug delivery systems; nanoparticles; nanomedicine; biomolecules; hydrogels; biomaterials

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Mitochondrial Function as a Target in Nanomedicine

edited by

Agnieszka Pyrczak-Felczykowska

submission deadline 31 Dec 2025 | Submission Open

Keywords: nanomedicine; nanoparticles; drug delivery; mitochondria; cancer; neurodegenerative disease; metabolism; targeted therapy; mitochondrial function; bioactive compounds.

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Inflammation in Neurogenerative Diseases: Mechanisms and Therapeutic Frontiers

edited by

Shao-Bin Wang

submission deadline 1 Jan 2026 | Viewed by 16 | Submission Open

Keywords: neuroinflammation; neurodegenerative diseases; biomarkers mitochondria dysfunction; microglia; immune response; therapeutic development; gene therapy

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Nanoparticles for Glioblastoma Therapy

edited by Shambhavi Pandey and

Benjamí Oller-Salvia

submission deadline 20 Jan 2026 | Viewed by 9 | Submission Open

Keywords: nanoparticles; blood& ndash; brain barrier; gene delivery; glioblastoma; cancer stem cells; biomaterials

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Advancements in Cardiac Imaging: Diagnostics, Prognostics, and Therapeutics

edited by Ilaria Dentamaro

submission deadline 31 Jan 2026 | 1 articles | Viewed by 634 | Submission Open

Keywords: cardiac imaging; echocardiography; cardiovascular magnetic resonance imaging; cardio CT; nuclear cardiology

(This special issue belongs to the Section Molecular and Translational Medicine)

Advancements and Challenges in Anticancer Targeted Therapy with Small Molecules

edited by Monika Papiez

submission deadline 31 Jan 2026 | Viewed by 232 | Submission Open

Keywords: small molecules; cancer; anticancer targeted therapy; cancer resistance; cancer growth blockers

(This special issue belongs to the Section Cancer Biology and Oncology)

New Advances in Epilepsy Research

edited by Duyu A. Nie

submission deadline 31 Jan 2026 | Viewed by 204 | Submission Open

Keywords: disease mechanisms; genetics; biomarkers; epilepsy surgery; electroencephalogram; animal models; artificial intelligence

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Parkinson’s Disease: Where Are We and Where Are We Going To

edited by Carmen Borrué

submission deadline 31 Jan 2026 | Viewed by 151 | Submission Open

Keywords: Parkinson’ s disease; gait disorders; biomarkers; neurodegenerative disease; AI

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances in Cardiovascular Diseases: Pathophysiological Insights, Therapeutic Strategies and Future Directions

edited by

Azizah Ugusman

, Wan Amir Nizam Wan Ahmad and Dharmani Devi Murugan

submission deadline 31 Jan 2026 | Viewed by 45 | Submission Open

Keywords: cardiovascular disease; pathophysiology; therapeutic strategies; translational research; complementary medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

New Advances in Biomaterials for Tissue Repair and Regeneration

edited by Fei Xing, Wen Nie and Zhao Chen

submission deadline 31 Jan 2026 | Viewed by 24 | Submission Open

Keywords: biomaterials; nanomaterials; tissue repair; 3D printing; functionals biomaterials; biomaterial science; tissue regeneration

(This special issue belongs to the Section Biomedical Engineering and Materials)

Metabolic Disorders and Their Complications: From Molecular Mechanisms to Therapeutic Perspectives

edited by

Sandeep Kumar

and

Abhishek Gupta

submission deadline 31 Jan 2026 | Viewed by 16 | Submission Open

Keywords: metabolism; diabetes; obesity; nutrition; AMPK and mTOR

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Antibody Responses to Viral Infections: Insights from Structural Biology

edited by Pragati Agnihotri and

Sharanbasappa Karade

submission deadline 31 Jan 2026 | Viewed by 14 | Submission Open

Keywords: crystal structure; virus– antibody complexes; broadly neutralizing antibodies; immunology; epitope mapping

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Nervous System Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by Natalia Rozas and Cameron Jeter

submission deadline 31 Jan 2026 | Viewed by 13 | Submission Open

Keywords: neurodegenerative diseases; neuromuscular diseases; autoimmune diseases of the nervous system; brain diseases; neuroinflammatory diseases; neuromuscular diseases; trauma of the nervous system

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Gut Microbiota, Diet, and Immunity: Investigating the Connections and Implications for Disease Development—3rd Edition

edited by

Farhad Vahid

submission deadline 31 Jan 2026 | Viewed by 10 | Submission Open

Keywords: gut microbiota; diet; immunity; microbiome; dysbiosis; inflammatory bowel diseases; cancer; CVD; T2D; obesity; overweight; autoimmune diseases; metabolic syndromes; immunomodulation; microbial diversity; nutrient– gut microbiota interactions; probiotics; prebiotics; immune system development; disease susceptibility; therapeutic interventions; host– microbe interactions; gut– brain axis; microbial metabolites; precision nutrition

(This special issue belongs to the Section Molecular and Translational Medicine)

Additive Manufacturing in Biomedical Applications

edited by

Paweł Turek

submission deadline 31 Jan 2026 | Viewed by 9 | Submission Open

Keywords: additive manufacturing; scaffolds; implant; anatomical models; in vivo; in vitro; surface texture; geometrical accuracy; biomaterials; surface roughness

(This special issue belongs to the Section Biomedical Engineering and Materials)

Pathogenesis, Diagnostics and Therapeutics in Obsterics and Gynaecology (2nd Edition)

edited by

Nikolaos Machairiotis

submission deadline 31 Jan 2026 | Viewed by 9 | Submission Open

Keywords: gynaecology; obstetrics; diagnosis; pathogenesis; treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Urothelial Carcinoma: Role of Biomarkers in Diagnosis, Prognosis and Treatment (2nd Edition)

edited by Ioannis Zachos and

Panagiotis Vlachostergios

submission deadline 31 Jan 2026 | Viewed by 8 | Submission Open

Keywords: urothelial carcinoma; biomarker; diagnosis; treatment; prognosis

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in 3D Printing for Drug Delivery Systems

edited by

Ion-Bogdan Dumitrescu

, Cristina Manuela Drăgoi and Alina Crenguța Nicolae

submission deadline 31 Jan 2026 | Viewed by 7 | Submission Open

Keywords: 3D printing; drug delivery systems; personalized medicine; pharmaceutical engineering; controlled release

(This special issue belongs to the Section Biomedical Engineering and Materials)

Pharmacogenetics and Pharmacogenomics: Driving Forces in Modern Precision Medicine

edited by Miriam Saiz-Rodríguez and Dora Koller

submission deadline 31 Jan 2026 | Viewed by 7 | Submission Open

Keywords: pharmacogenetics; pharmacogenomics; precision medicine; polygenic risk scores; phenoconversion; drug response; genetic biomarkers; personalized therapy; underrepresented populations; clinical implementation

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Advances in Allergies and Autoimmunity

edited by

Mukesh Verma

submission deadline 31 Jan 2026 | Viewed by 6 | Submission Open

Keywords: asthma; arthritis; diabetes; inflammatory bowel disease; dermatomyositis; Sjö gren's syndrome; systemic lupus erythematosus; psoriasis; multiple sclerosis

(This special issue belongs to the Section Cell Biology and Pathology)

New Advances in Human Reproductive Biology

edited by

Nikolaos Machairiotis

submission deadline 31 Jan 2026 | Viewed by 6 | Submission Open

Keywords: gametogenesis; fertilization; egg retrieval; embryo implantation; epigenetics; microRNAs in fertility; hormonal signaling; stem cells and fertility; assisted reproductive technologies; molecular and polymorphism in fertility; reproductive health novelty

(This special issue belongs to the Section Molecular and Translational Medicine)

Displaying special issue 651-700 on page 14 of 15.

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