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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Drug Delivery and Nanocarrier

edited by

Jiawei Huo

submission deadline 31 Mar 2026 | Viewed by 62 | Submission Open

Keywords: nanocarriers; targeted drug delivery; controlled release; theranostics; biocompatibility; functionalized nanoparticles; nanomedicine; translational nanotechnology

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Innovations in Radiation Oncology

edited by

Caressa Hui

submission deadline 31 Mar 2026 | Viewed by 61 | Submission Open

Keywords: adaptive radiotherapy; cancer biomarkers; genomics; artificial intelligence; radiation oncology; machine learning; precision oncology; radiogenomics; ctDNA

(This special issue belongs to the Section Cancer Biology and Oncology)

Natural and Synthetic Molecules with Anticancer Activity: Pharmacological Basis and Mechanistic Insight—2nd Edition

edited by

Hassan Ebrahim

and

Ángela Patricia Hernandez

submission deadline 31 Mar 2026 | Viewed by 61 | Submission Open

Keywords: anticancer; molecular pharmacology; mechanistic mode of action; signal transduction; in vitro; preclinical; natural products; synthesis

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Leishmaniasis: Pathophysiology, Diagnostics and Current and Emerging Therapeutic Approaches—2nd Edition

edited by Raimunda Nonata Ribeiro Sampaio

submission deadline 31 Mar 2026 | Viewed by 60 | Submission Open

Keywords: leishmaniasis; pathophysiology; neglected infectious diseases

(This special issue belongs to the Section Molecular and Translational Medicine)

Glioblastoma: Novel Multitargeted Approaches

edited by

Wenjing Zeng

submission deadline 31 Mar 2026 | Viewed by 54 | Submission Open

Keywords: glioblastoma; multitargeted therapy; tumor heterogeneity; immunotherapy; targeted agents; nanomedicine; RNA therapeutics; combination therapy; translational oncology

Advancements in the Treatment of Colorectal Cancer

edited by

Andee Dzulkarnaen Zakaria

submission deadline 31 Mar 2026 | Viewed by 52 | Submission Open

Keywords: genomic profiling; advanced nutritional support; AI; MDT; adjuvant therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Molecular and Cellular Mechanisms in Metabolic Bone and Cartilage Disorders

edited by

Mohamad Alaa Terkawi

submission deadline 31 Mar 2026 | Viewed by 52 | Submission Open

Keywords: metabolic bone; cartilage disorders; osteoporosis; osteoarthritis; impaired fracture healing; rare metabolic skeletal diseases

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Advances in Cancer Biology and Experimental Anticancer Therapies (3rd Edition)

edited by

Letizia Polito

and

Ewa Gajda

submission deadline 31 Mar 2026 | Viewed by 51 | Submission Open

Keywords: cancer biology; experimental anticancer therapies; immunotherapy; immunotoxins; signalling pathways; targeted therapies

(This special issue belongs to the Section Cancer Biology and Oncology)

Current Perspectives on Human Papillomavirus (HPV)—Second Edition

edited by

Vanja Kaliterna

and

Tomislav Meštrović

submission deadline 31 Mar 2026 | Viewed by 48 | Submission Open

Keywords: human papillomavirus (HPV); molecular mechanisms; diagnosis; treatment; prevention; vaccination; screening; immunotherapy; cancer

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Next-Generation CRISPR and Immune Modulation: Advancing Precision Genome Editing Therapies for Genetic Disorders

edited by Sukanta Jash

submission deadline 31 Mar 2026 | Viewed by 47 | Submission Open

Keywords: CRISPR/Cas9; base editors; prime editors; innate immunity; genome editing; off-target effects; delivery vectors; monogenic disorders; multiplex editing; AI-driven CRISPR

(This special issue belongs to the Section Gene and Cell Therapy)

Recent Advances in Antiviral and Antibacterial Drugs

edited by

Mohammad Anwar Hossain

submission deadline 31 Mar 2026 | Viewed by 47 | Submission Open

Keywords: viral infection; direct-acting antiviral; antimicrobial resistance (AMR); pandemic preparedness; antiviral therapy; infectious disease; viral resistance

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Aortic Aneurysm: Mechanisms, Biomarkers, and Therapeutic Strategy

edited by

Mitra Esfandiarei

and

Seda Selamet Tierney

submission deadline 31 Mar 2026 | Viewed by 47 | Submission Open

Keywords: aortic aneurysms; genetic aortic diseases; endothelial dysfunction; extracellular matrix; aortic wall; aortic smooth muscle; angiotensin system; aortic wall elasticity; matrix metalloproteinases

(This special issue belongs to the Section Molecular and Translational Medicine)

Chronic Vascular Impairment in Heart, Brain, and Kidney Disorders: Molecular Mechanisms and Therapeutic Strategies

edited by

Mahdi O. Garelnabi

submission deadline 31 Mar 2026 | Viewed by 44 | Submission Open

Keywords: atherosclerosis; lipoprotein; inflammation; antioxidants; oxidative stress; cardiovascular diseases; neurodegenerative disorders; blood– brain barrier; stroke; Alzheimer's disease; kidney

(This special issue belongs to the Section Cell Biology and Pathology)

Head and Neck Cancer: Molecular Mechanisms to Therapeutic Advances

edited by Jacopo Zocchi, Irene H. Nauta and

Carlos M. Chiesa-Estomba

submission deadline 31 Mar 2026 | Viewed by 42 | Submission Open

Keywords: head and neck cancer; molecular mechanisms; molecular biomarkers; immunotherapy; liquid biopsy; treatment resistance; targeted therapies; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Bone Metabolism, Bone Homeostasis and Osteogenesis

edited by

Youngjae Jeong

and Laura Ortinau

submission deadline 31 Mar 2026 | Viewed by 42 | Submission Open

Keywords: bone homeostasis and maintenance; bone remodeling; osteoblast– osteoclast interaction; endocrine signaling by bone; bone metabolic disease

(This special issue belongs to the Section Cell Biology and Pathology)

Molecular Psychiatry and Antipsychotics

edited by

László Péczely

submission deadline 31 Mar 2026 | Viewed by 41 | Submission Open

Keywords: psychiatric diseases; schizophrenia; antipsychotics; molecular psychiatry; molecular pathways; neurotransmitter systems; positive; negative and cognitive symptoms

(This special issue belongs to the Section Molecular and Translational Medicine)

High-Risk Atrial Fibrillation in Patients with Cardiovascular Disease: Diagnosis, Comprehensive Risk Assessment, Comorbidities, and Anticoagulation Strategies

edited by

Silvia Reverté-Villarroya

and

José-Luis Clúa-Espuny

submission deadline 31 Mar 2026 | Viewed by 41 | Submission Open

Keywords: atrial fibrillation; cardiovascular comorbidity; device-detected atrial fibrillation; treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Gastrointestinal Diseases: From Pathophysiology to Therapeutics

edited by Ali H. Zaidi and Neda Dadgar

submission deadline 31 Mar 2026 | Viewed by 41 | Submission Open

Keywords: gastrointestinal diseases; pathophysiology; gastrointestinal cancer; esophageal cancer; gastric cancer; colorectal cancer; pancreatic cancer; hepatocellular cancer; appendiceal cancer; cancer biomarker

(This special issue belongs to the Section Molecular and Translational Medicine)

Brain Disorders: Bridging Molecular Insights and Innovative Therapies

edited by

Karol Wiśniewski

and

Bartosz Szmyd

submission deadline 31 Mar 2026 | Viewed by 41 | Submission Open

Keywords: neurosurgery; neuro-oncology; glioma; innovations; cancer predisposing syndrome; neurofibromatosis; CMMRD

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Autoimmune and Inflammatory Disorders: From Pathogenesis to Therapeutic Targeting

edited by

Yu-Wei Chang

submission deadline 31 Mar 2026 | Viewed by 39 | Submission Open

Keywords: inflammasome; inflammation; sepsis; autoimmune; microbiota; immunomodulation

(This special issue belongs to the Section Immunology and Immunotherapy)

Next-Generation Approaches to Hepatobiliary Disorders

edited by

Lorenzo Petagna

submission deadline 31 Mar 2026 | Viewed by 38 | Submission Open

Keywords: hepatobiliary disorders; interventional radiology; interventional endoscopy; advances in HPB surgery; advances in liver transplantation; liver transplant viability biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Post-Viral Syndromes and Long-Term Health Impacts

edited by Sophia X. Sui

submission deadline 31 Mar 2026 | Viewed by 38 | Submission Open

Keywords: post-viral syndrome; long COVID; ME/CFS; immune dysregulation; neuroinflammation; metabolism; biomarkers; therapeutic targets; basic research; translational research

(This special issue belongs to the Section Molecular and Translational Medicine)

Insulin Resistance and Hyperinsulinemia: From Molecular Mechanisms to Clinical Translation

edited by

Anindya Ghosh

submission deadline 31 Mar 2026 | Viewed by 35 | Submission Open

Keywords: insulin resistance; type 2 diabetes; metabolic syndrome; obesity

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Pulmonary Arterial Hypertension: From Molecular Basis to Therapeutic Approaches—2nd Edition

edited by

Rui Adão

submission deadline 31 Mar 2026 | Viewed by 34 | Submission Open

Keywords: pulmonary arterial hypertension; right ventricle; right heart failure; therapy; vascular disease; translational research

(This special issue belongs to the Section Molecular and Translational Medicine)

Applications of Biomedical Engineering and Biomaterials in Human Diseases

edited by Rui Sang

submission deadline 31 Mar 2026 | Viewed by 34 | Submission Open

Keywords: biosensors and diagnostics; biomedical engineering; nanotechnology in medicine; artificial intelligence in healthcare; precision medicine; drug delivery systems; regenerative medicine; 3D bioprinting; CRISPR-based technologies

(This special issue belongs to the Section Biomedical Engineering and Materials)

Pancreatic Cancer: From Mechanisms to Therapeutic Approaches (4th Edition)

edited by

Satoshi Wada

submission deadline 31 Mar 2026 | Viewed by 31 | Submission Open

Keywords: pancreatic cancer; tumor microenvironment; biomarker; immune environment in pancreatic cancer

(This special issue belongs to the Section Cancer Biology and Oncology)

Emerging Trends in Reproductive Endocrinology and Pregnancy-Related Disorders

edited by

Theodoros Kalampokas

submission deadline 31 Mar 2026 | Viewed by 30 | Submission Open

Keywords: pregnancy-related disorders; eclampsia; preeclampsia; hypertensive disorders of pregnancy; gestational diabetes; reproductive endocrinology; precision medicine

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Emerging Trends and Applications in Nanomedicine and Targeted Therapies

edited by

Marzieh Ramezani Farani

submission deadline 31 Mar 2026 | Viewed by 29 | Submission Open

Keywords: nanomedicine; drug delivery systems; targeted therapy; biomaterials; cancer therapy; smart nanocarriers; biodegradable nanoparticles; photothermal therapy; nano-diagnostics; translational nanotechnology

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Pathology, Complications, and Prognosis of Type 1 Diabetes (T1D)

edited by Tadesse Melaku Abegaz

submission deadline 31 Mar 2026 | Viewed by 27 | Submission Open

Keywords: type 1 diabetes; complications; prognosis; cardiovascular disease; neuropathy; retinopathy; nephropathy; disease mechanisms; clinical outcomes

(This special issue belongs to the Section Endocrinology and Metabolism Research)

The Role of Cytokines in Health and Disease: 3rd Edition

edited by

Monika Zajkowska

submission deadline 20 Apr 2026 | 5 articles | Viewed by 3990 | Submission Open

Keywords: cytokine; chemokine; neurodegenerative disease; cancer; inflammatory mediator; diagnosis; biomarker

(This special issue belongs to the Section Cell Biology and Pathology)

Cellular and Molecular Mechanisms in Gastrointestinal Tract Disease: 2nd Edition

edited by Felipe Leite De Oliveira

submission deadline 29 Apr 2026 | Viewed by 48 | Submission Open

Keywords: cellular mechanisms; molecular mechanisms; diagnosis; treatment; experimental models; signaling pathways; comorbidities

(This special issue belongs to the Section Cell Biology and Pathology)

Thyroid Disorders: Current Status and Future Prospects

edited by Anna Małgorzata Kucharska

submission deadline 30 Apr 2026 | 3 articles | Viewed by 4692 | Submission Open

Keywords: thyroid diseases; autoimmune thyroid diseases; hypothyroidism; hyperthyroidism; treatment; children; adults

(This special issue belongs to the Section Molecular and Translational Medicine)

Biomedicine in Dental and Oral Rehabilitation

edited by

Sanda Mihaela Popescu

and

Mihaela Ionescu

submission deadline 30 Apr 2026 | 2 articles | Viewed by 1568 | Submission Open

Keywords: diagnosis; treatment; oral rehabilitation; dental and oral disease; biomedicine; biomaterial; regeneration; functional; esthetics

(This special issue belongs to the Section Biomedical Engineering and Materials)

New Perspectives in the Treatment of Head and Neck Vascular Malformations

edited by Paolo Gennaro

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1433 | Submission Open

Keywords: vascular anomalies; vascular malformations; AVMs; venous malformations; electrosclerotherapy

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Stroke Neuroprotection and Repair

edited by

Konstantinos Tsamakis

submission deadline 30 Apr 2026 | 1 articles | Viewed by 961 | Submission Open

Keywords: stroke; cerebral infarction; neuronal damage; neural regeneration; neuroprotection

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Innovative Approaches in Drug Discovery

edited by Jitendra Gour

submission deadline 30 Apr 2026 | Viewed by 693 | Submission Open

Keywords: PROTACs; molecular glue; personalized medicine; high-throughput screening (HTS); targeted therapy; drug repurposing; safety profiles

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Advances in Skin Tumors: From Pathogenesis to Treatment Strategies

edited by Zhongxin Yu and Sepideh Nikki Asadbeigi

submission deadline 30 Apr 2026 | 1 articles | Viewed by 635 | Submission Open

Keywords: melanoma skin; tumor epigenetic alterations; genetic mutations; tumor microenvironment immunotherapy; targeted therapy; nanomedicine

(This special issue belongs to the Section Cancer Biology and Oncology)

Recent Advances in Hypertension, Hypercholesterolemia and Type 2 Diabetes—2nd Edition

edited by

Tomislav Bulum

submission deadline 30 Apr 2026 | Viewed by 558 | Submission Open

Keywords: type 2 diabetes; hypertension; LDL-cholesterol; serum lipids; metabolic syndrome; cardiovascular disease; chronic complications; nephropathy

(This special issue belongs to the Section Endocrinology and Metabolism Research)

New Challenges in Liver Diseases: From Molecular Pathogenesis to Therapeutic Approaches

edited by Yefu Wang

submission deadline 30 Apr 2026 | 1 articles | Viewed by 269 | Submission Open

Keywords: liver fibrosis; NAFLD/NASH; ACLF; HBV cure; immunotherapy; precision medicine; metabolic liver diseases; gut– liver axis; regenerative medicine; biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Nanoparticle-Labeled Exosomes as Theranostic Agents

edited by Karrer M. Alghazali

submission deadline 30 Apr 2026 | Viewed by 164 | Submission Open

Keywords: exosomes; nanotheranostic agent; nanoparticles; exosome labeling; photothermal therapy; drug delivery vehicle; imaging probe

(This special issue belongs to the Section Cell Biology and Pathology)

Intracellular Optogenetics Tools to Probe Biological Signaling Pathways

edited by

Qunxiang Ong

submission deadline 30 Apr 2026 | Viewed by 150 | Submission Open

Keywords: optogenetics; signaling transduction; neuroscience; immunology; cancer signaling; synthetic biology; spatiotemporal resolution

(This special issue belongs to the Section Molecular and Translational Medicine)

Emerging Trends in Kidney Disease (2nd Edition)

edited by Andrea Angioi

submission deadline 30 Apr 2026 | Viewed by 114 | Submission Open

Keywords: kidney disease; glomerular diseases; vasculitis; dialysis; hypertension; pediatric nephrology; transplantation; precision medicine; therapeutic advancements

(This special issue belongs to the Section Molecular and Translational Medicine)

Mechanobiology and Extracellular Vesicle-Based Strategies for Osteochondral Regeneration

edited by Zhen Yang

submission deadline 30 Apr 2026 | Viewed by 103 | Submission Open

Keywords: biomechanics; stem cells; osteoarthritis; tissue engineering; extracellular vesicles

(This special issue belongs to the Section Biomedical Engineering and Materials)

Gastrointestinal Diseases: From Pathophysiology to Innovative Therapeutic Approaches

edited by

Francisco Tustumi

submission deadline 30 Apr 2026 | Viewed by 68 | Submission Open

Keywords: gastrointestinal diseases; pathophysiology; microbiome; inflammation; gastrointestinal cancer; translational medicine; therapeutic innovation; personalized treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Natural and Synthetic Anticancer Agents: Mechanistic Insights and Translational Pathways

edited by

Gul-E-Saba Chaudhry

submission deadline 30 Apr 2026 | Viewed by 64 | Submission Open

Keywords: cancer; drug discovery; synthetic anti-cancer; natural bioactive compounds; nano targeted targeted drug delivery; cancer biomarkers; mechanism of cell death; novel anti-cancer compounds

(This special issue belongs to the Section Cancer Biology and Oncology)

Bone Metabolism in Health and Disease

edited by

Kun Chen

submission deadline 30 Apr 2026 | Viewed by 62 | Submission Open

Keywords: bone remodeling; skeletal stem cells; osteocyte; osteoblasts; osteoclasts; osteoporosis; osteoarthritis; bone regeneration; bone aging; bone therapeutics

(This special issue belongs to the Section Molecular and Translational Medicine)

Mechanisms and Novel Therapeutic Approaches for Gliomas: 2nd Edition

edited by Maria V. Chatziathanasiadou

submission deadline 30 Apr 2026 | Viewed by 59 | Submission Open

Keywords: glioma; molecular mechanisms; tumour immunity; tumour metabolism; tumour microenvironment; metabolic therapies; immunotherapies; combination treatment

(This special issue belongs to the Section Cancer Biology and Oncology)

Genome Engineering Technologies for Diseases

edited by Kosuke Ishikawa

submission deadline 30 Apr 2026 | Viewed by 56 | Submission Open

Keywords: genome engineering; gene editing; gene delivery; transposable elements; insertinal mutagenesis; functional genomics; in silico analysis; cell-based assays; disease modeling; cell therapy

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Advances in Ocular Surface Disease

edited by

Kofi Asiedu

submission deadline 30 Apr 2026 | Viewed by 54 | Submission Open

Keywords: dry eye disease; corneal neuroimmune interactions; meibomian gland dysfunction; microbial keratitis; ocular allergy; corneal degeneration

(This special issue belongs to the Section Molecular and Translational Medicine)

Selective Glucocorticoid Receptor Agonists and Modulators (SEGRAMs)

edited by

Dimitra Mitsiou

submission deadline 30 Apr 2026 | Viewed by 45 | Submission Open

Keywords: glucocorticoid receptor; glucocorticoids; transactivation; transrepression; selective glucocorticoid receptor agonists; selective glucocorticoid receptor modulators; inflammation; anti-inflammatory action; side effects; therapeutic potential

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Displaying special issue 651-700 on page 14 of 16.

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