Advanced Research in Liver Diseases
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 26
Special Issue Editor
Special Issue Information
Dear Colleagues,
Liver homeostasis relies on the dynamic and continuous processing of drugs, products of metabolic pathways, and vitamins. The balance between homeostasis and diseased states strictly depends on the liver's ability to eliminate toxic molecules through transient activation of oxidative stress pathways with the goal to return to physiologic states. In numerous liver disorders with high prevalence globally, such a balance is lost, a pattern that includes liver disorders associated with obesity, type 2 diabetes, alcohol, hepatitis, and drug intoxication, among many other causes. Although in the last decade cutting-edge technologies have contributed to dissecting critical molecular and biochemical mechanisms underlying the pathogenesis of liver diseases, there is still an unmet need to further characterize key mechanisms of disease initiation and progression that will help find better therapeutic targets, especially for liver disorders with no approved therapies yet.
The focus of this Special Issue is to publish research that explores the mechanisms of liver disease, from delving into the ultrastructure of key organelles to uncovering cell–cell interactions and communications. This Special Issue seeks to publish the most recent advances in the field of liver diseases that will propel the field to tackle some of the questions that prevent a clear understanding of disease mechanisms and, ultimately, the development of therapeutic molecular targets.
Dr. Marta Melis
Guest Editor
Manuscript Submission Information
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Keywords
- liver
- obesity
- alcohol
- oxidative stress
- nutrients
- vitamins
- metabolism
- homeostasis
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