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Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Oxidative Stress in Striated Muscle and Other Tissues

edited by

Enrique Jaimovich

submission deadline 30 Jun 2025 | 1 articles | Viewed by 998 | Submission Open

Keywords: ROS/RNS production; mitochondria ROS; NADPH oxidase; metabolic regulation; cardiac oxidative stress; ROS sources; exercise-induced ROS/RNS; antioxidants; ROS/RNS in disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Polyphenolic Antioxidants in Food

edited by

Avi Shpigelman

and

Jelena Popović-Djordjević

submission deadline 30 Jun 2025 | 1 articles | Viewed by 915 | Submission Open

Keywords: polyphenols; antioxidant activity; bio-functionality; food sources; health benefits; polyphenol analytics

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Role of Antioxidants and Oxidative Stress in Neurodegenerative Diseases

edited by

Barbara Sottero

submission deadline 30 Jun 2025 | 1 articles | Viewed by 618 | Submission Open

Keywords: neurodegenerative diseases; antioxidants; oxidative stress; Parkinson’ s disease; Alzheimer’ s disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Activity of Olive Extracts and Their Applications

edited by

Alejandra Bermudez-Oria

and Fátima Rubio-Senent

submission deadline 30 Jun 2025 | Viewed by 493 | Submission Open

Keywords: olive extracts; antioxidant activity; polyphenols; carotenoids; chlorophylls; tocopherol; oxidative stress; cellular damage prevention; health benefits; extraction methods; green extraction techniques; nutritional applications; cosmetic applications

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

H₂S, Polysulfides and Antioxidases in Supporting Life: From Bacteria to Humans

edited by

Noriyuki Nagahara

submission deadline 30 Jun 2025 | Viewed by 461 | Submission Open

Keywords: H2S; polysulfides; antioxidases; bacteria; human

Oxidative Stress to DNA: Pathogenic Mechanism and Therapeutic Opportunity

edited by

Marco Giorgio

submission deadline 30 Jun 2025 | Viewed by 359 | Submission Open

Keywords: DNA damage; oxidative stress; antioxidants; epigenetics; aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

High-Fat Diet-Induced Oxidative Stress

edited by

María Teresa Llinas Más

and

Isabel Hernández

submission deadline 30 Jun 2025 | Viewed by 336 | Submission Open

Keywords: saturated fats; fats; high-fat diet; obesity; cardiovascular disease; non-alcoholic fatty liver disease; oxidative stress; antioxidants; cancer; neurodegenerative diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants from the Sea and Their Application

edited by

Daniela Giordano

and

Chiara Lauritano

submission deadline 30 Jun 2025 | Viewed by 248 | Submission Open

Keywords: marine natural products; marine enzymes; marine nutraceuticals; marine cosmeceuticals; food supplements; antioxidant mechanisms of action; structure– function relationship; antioxidant capacity; biotechnological application; biotechnological production

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Super Oxide Dismutase (SOD) Isoenzymes and Reactive Oxygen Species (ROS) in Immuno-Pathophysiology

edited by Giuseppina Ruggiero and

Paolo Mondola

submission deadline 30 Jun 2025 | Viewed by 239 | Submission Open

Keywords: superoxide dismutase (SOD) isoenzymes; superoxide dismutase (SOD)1; cell signalling; cell metabolism; cell functions; cellular stress; disease pathogenesis

Exploring the Role of Polyphenols in Oxidative Stress and Cellular Protection

edited by

Lucia Gimeno-Mallench

submission deadline 30 Jun 2025 | Viewed by 220 | Submission Open

Keywords: polyphenol; oxidative stress; cellular signaling; metabolic pathways

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants in Drugs and Health Products

edited by

Maria N. Modica

submission deadline 30 Jun 2025 | Viewed by 172 | Submission Open

Keywords: antioxidants; human diseases; polyphenols; hybrid compounds; drugs

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Sleep Disorders

edited by

Agata Gabryelska

submission deadline 30 Jun 2025 | Viewed by 151 | Submission Open

Keywords: sleep disorders; sleep apnea; insomnia; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Role of Redox in Pulmonary Vascular Diseases

edited by

Michael S. Wolin

and Sachin Gupte

submission deadline 1 Jul 2025 | 2 articles | Viewed by 2680 | Submission Open

Keywords: hypoxic pulmonary vasoconstriction; metabolic redox regulation; pulmonary circulation; pulmonary hypertension; pulmonary vascular disease; redox signaling

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

New Strategies in Preventing Inflammatory and/or Oxidative Stress-Induced Damages in Ischemia-Reperfusion Injury, 2nd Edition

edited by

Borja Herrero de la Parte

Ignacio García-Alonso

and

Ana Alonso-Varona

submission deadline 10 Jul 2025 | 8 articles | Viewed by 8006 | Submission Open

Keywords: ischemia– reperfusion injury; reactive oxygen species; hypoxia; antioxidants; therapeutic management

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant and Antimicrobial Activity of Plant Extracts and Their Pharmacological Applications

edited by

Andrea Bunea

Sanda Andrei

and

Mihai Cosmin Cenariu

submission deadline 15 Jul 2025 | 4 articles | Viewed by 7042 | Submission Open

Keywords: plant extracts; polyphenols; carotenoids; antioxidants; antimicrobials; oxidative stress; microbial infections; herbal remedies; synergistic effects; therapeutic efficacy; safety profiles; natural alternatives

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Reactive Oxygen and Nitrogen Species in Plants―2nd Edition

edited by

Francisco J. Corpas

Rosa M. Rivero

and

José M. Palma

submission deadline 15 Jul 2025 | 3 articles | Viewed by 5124 | Submission Open

Keywords: antioxidants; hydrogen peroxide; nitric oxide; nitro-oxidative stress; ROS; RNS; hydrogen sulfide; melatonin

(This special issue belongs to the Section ROS, RNS and RSS)

Oxidative Stress and Neuroinflammation in Neurodegenerative Diseases: Mechanisms and Therapies

edited by Ana M. Munoz and

Jannette Rodríguez-Pallares

submission deadline 20 Jul 2025 | 10 articles | Viewed by 19588 | Submission Open

Keywords: neurodegeneration; aging; neuroprotection; mitochondrial dysfunction; cytokines; apoptosis; autophagy; microglia; astroglia; antioxidants; free radicals

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Phenolic Antioxidants—2nd Edition

edited by

Adriano Costa de Camargo

and

Fereidoon Shahidi

submission deadline 20 Jul 2025 | 1 articles | Viewed by 825 | Submission Open

Keywords: phenolics; phenolic compounds; antioxidants

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Something Is Rotten in the State of Redox—2nd Edition

edited by

Claus Jacob

Muhammad Jawad Nasim

and

Ahmad Yaman Abdin

submission deadline 20 Jul 2025 | Viewed by 242 | Submission Open

Keywords: antioxidants; antioxidant mechanisms; ageing and age-related diseases; oxidative stress; redox biology

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Effect of Oxidative Stress on Reproduction and Development—3rd Edition

edited by

Giulia Guerriero

and

Gerardino D’Errico

submission deadline 20 Jul 2025 | Viewed by 199 | Submission Open

Keywords: free radicals and antioxidants; oxidative stress in male and female reproduction; mitochondria; gametogenesis; assisted reproduction; thermal fertility limit (TFL); climate change; one-health; biodiversity conservation and sustainability; reproduction; development and nutrigenomics; methods for reactive oxygen species detection and antioxidant property determination.

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Brain Function—2nd Edition

edited by

Waldo Cerpa

submission deadline 21 Jul 2025 | 4 articles | Viewed by 4421 | Submission Open

Keywords: pathophysiological brain regulation; brain function; oxidative stress; brain damage; neurodegeneration; cellular signaling; neurotoxicity; excitotoxicity; synaptic transmission; cognitive function

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Dietary Polyphenols: Antioxidant Potential and Health Benefits

edited by

Małgorzata Olszowy-Tomczyk

submission deadline 25 Jul 2025 | Viewed by 310 | Submission Open

Keywords: dietary polyphenols; antioxidant properties; anticancer action; antimicrobial properties; anti-inflammatory actions; flavonoids; phenolic acids

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Protein Oxidative Modification in Brain Function, Brain Ageing and Neurological Diseases—2nd Edition

edited by

Sandra Anjo

Andreia N. Carvalho

and

Mattéa J. Finelli

submission deadline 25 Jul 2025 | Viewed by 301 | Submission Open

Keywords: protein oxidative modifications; post-translational modifications; S-glutathionylation; S-nitrosylation/S-nitrosation; persulfidation; redox signaling; oxidative and nitrosative stresses; cysteine oxidation; antioxidants; redox-based pharmacological/therapeutic approaches; mitochondrial dysfunction; mitochondria-targeted molecules; brain function and ageing; neurological/neurodegenerative diseases; proteomics

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Biology of Glyoxalases and Advanced Glycation End Products in Health and Diseases

edited by

Cinzia Antognelli

Marilena Pariano

and

Vincenzo Nicola Talesa

submission deadline 25 Jul 2025 | Viewed by 203 | Submission Open

Keywords: glyoxalases; methylglyoxal; advanced glycation end products; aging; diseases; antioxidants; apoptosis; cell proliferation; nutraceuticals; oxidative stress; inflammation; apoptosis; EMT; cell proliferation; signal transduction; biological mechanisms

(This special issue belongs to the Section Antioxidant Enzyme Systems)

The Role of Oxidative Stress in Male Infertility

edited by

Suresh C. Sikka

submission deadline 30 Jul 2025 | 3 articles | Viewed by 2878 | Submission Open

Keywords: male infertility; seminal reactive oxygen species; sperm; reactive nitrogen species; antioxidant

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Its Mitigation in Neurodegenerative Disorders

edited by

D. Allan Butterfield

submission deadline 30 Jul 2025 | 1 articles | Viewed by 737 | Submission Open

Keywords: oxidative stress; neurodegenerative disorders; brain; Alzheimer’ s disease; Parkinson’ s disease; Huntington’ s disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Nrf2 and Cardiovascular Function, Diseases, and Therapeutic Targets

edited by

Gao Lie

and

Irving H. Zucker

submission deadline 30 Jul 2025 | Viewed by 366 | Submission Open

Keywords: nuclear factor erythroid 2-related factor 2 (Nrf2); Nrf2-targeted therapies; cardiovascular diseases; antioxidant; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Defenses Against Stress Caused by Physical or Chemical Environmental Changes

edited by

Paola Irato

submission deadline 30 Jul 2025 | 1 articles | Viewed by 308 | Submission Open

Keywords: antioxidant defenses; oxidative stress; redox state; physical stress; chemical stress; environmental changes; kingdoms living; heat stress; UV light; CO2 and O3; heavy metals

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Environmental Risk Factors and Oxidative Stress in the Retina

edited by

Adrian Gericke

submission deadline 30 Jul 2025 | Viewed by 135 | Submission Open

Keywords: environment; pollution; oxidative stress; retina

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Phytochemicals for Promoting Human Health and Well-Being

edited by

Teresa Mencherini

Francesca Sansone

and

Tiziana Esposito

submission deadline 30 Jul 2025 | Viewed by 133 | Submission Open

Keywords: antioxidant phytochemicals; oxidative stress; health promotion; chronic disease; functional foods; nutraceuticals

Antioxidant Response in Skeletal Muscle

edited by Jan Górski and

Elzbieta Supruniuk

submission deadline 31 Jul 2025 | 4 articles | Viewed by 10162 | Submission Open

Keywords: antioxidants; skeletal muscle; exercise; muscle injury; metabolic diseases; muscle dystrophy; cancer; immobilization

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant and Antimicrobial Activity of Honey Bee Products—2nd Edition

edited by

Josipa Vlainić

and

Ivana Tlak Gajger

submission deadline 31 Jul 2025 | 6 articles | Viewed by 7584 | Submission Open

Keywords: honey bee products; antioxidant capacity; antimicrobial efficacy; polyphenol content; functional food; health promotion

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Oxidative Stress and NRF2 in Health and Disease—2nd Edition

edited by

Lidija Milković

submission deadline 31 Jul 2025 | 3 articles | Viewed by 4526 | Submission Open

Keywords: oxidative stress; redox signaling; NRF2 and its regulation; redox-modifying therapeutic approach; omics approach; physiology; non-communicable diseases; metabolism; aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Harnessing Redox Status and Novel Molecular Signals and Targets Involved in Oxidative Stress to Afford Cardioprotection: From Experimental Insights to Clinical Applications

edited by

Tommaso Angelone

Carmine Rocca

and Anna De Bartolo

submission deadline 31 Jul 2025 | 2 articles | Viewed by 3134 | Submission Open

Keywords: oxidative stress; redox signaling; cardioprotection; antioxidants; heart disease; vascular dysfunction; molecular targets; therapeutic approaches

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Influence of Gut Microbiota on Antioxidant Capacity of Foods—2nd Edition

edited by

Sergio Pérez Burillo

and

José Ángel Rufián-Henares

submission deadline 31 Jul 2025 | 1 articles | Viewed by 2530 | Submission Open

Keywords: antioxidant capacity; antioxidant molecules; polyphenols; gut microbiota; microbial metabolites

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Oxidative and Nitrosative Stress in Male Reproduction

edited by

Pamela Uribe

and

Raúl Sánchez

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2263 | Submission Open

Keywords: oxidative stress; nitrosative stress; reactive oxygen species; reactive nitrogen species; spermatozoa; sperm motility; sperm function; antioxidants

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Delivery Strategies for Prevention and Treatment of Skin Pathologies

edited by

Elisabetta Esposito

submission deadline 31 Jul 2025 | 3 articles | Viewed by 1859 | Submission Open

Keywords: drug delivery systems; skin delivery; antioxidant actives; skin pathologies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Novel Approaches in Natural Occuring Antioxidants in the Prevention and Treatment of Chronic Diseases, 2nd Edition

edited by

Christos Kontogiorgis

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1752 | Submission Open

Keywords: nutracuticals; antioxidants; phytochemicals; in vitro studies; in vivo studies; extracts; isolated compounds; chronic diseases; prevention; treatment; therapeutic

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Advanced in Antioxidant Signalling Mediators/Effectors in Skeletal Muscle Disorders

edited by

Elisabetta Meacci

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1724 | Submission Open

Keywords: antioxidants; vitamins; skeletal muscle; signalling pathway effectors

(This special issue belongs to the Section Aberrant Oxidation of Biomolecules)

Developmental Origins of Health and Disease: Antioxidants as Strategy for Prevention and Treatment

edited by

Silvia M. Arribas

and

David Ramiro-Cortijo

submission deadline 31 Jul 2025 | 1 articles | Viewed by 757 | Submission Open

Keywords: oxidative stress; pregnancy; germline damage; obstetric complications; fetal programming

Oxidative Stress in Metabolic Disorders and Non-Communicable Diseases (NCDs): Molecular Pathways and Genetic Influence

edited by

Roberta Giordo

submission deadline 31 Jul 2025 | 1 articles | Viewed by 431 | Submission Open

Keywords: metabolic disorders; non-communicable diseases (NCDs); reactive oxygen species (ROS); genetic influence; molecular pathways

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Resilience Signaling of Functional Nutrients and Neurotoxicant Pollutants for Human Health

edited by

Maria Scuto

and

Angela Trovato Salinaro

submission deadline 31 Jul 2025 | Viewed by 219 | Submission Open

Keywords: dietary nutrients; polyphenol-basaed nanoparticles; oxidative stress; apoptosis; ferroptosis; pyroptosis; hormesis; inflammation; human health; toxicant pollutants; apoptosis; cancer; nervous system disorders; personalized nutritional therapy

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Human Serum Albumin: The Role of Cys34 and Nucleophilic Sites in Oxidative Stress and in the Detoxification of Endogenous and Xenobiotic Electrophilic Compounds

edited by

Giancarlo Aldini

Alessandra Altomare

and

Giovanna Baron

submission deadline 31 Jul 2025 | Viewed by 187 | Submission Open

Keywords: Cys34; cysteine residue; mercaptoalbumin; oxidative stress; oxidative stress-based diseases

(This special issue belongs to the Section Aberrant Oxidation of Biomolecules)

Innovations in Drug Delivery Systems for Antioxidant-Based Therapeutic Agents

edited by

Judit Váradi

submission deadline 31 Jul 2025 | Viewed by 183 | Submission Open

Keywords: antioxidant; bioaccessibility/bioavailability; stability; controlled release; drug delivery system; nanoparticles; nano-carriers

Diabetic Retinopathy and Oxidative Stress: Molecular Mechanisms, Diagnostic Strategies, and Advances in Antioxidant Therapies

edited by

Ángel Luis Ortega

and

Juan Gambini

submission deadline 31 Jul 2025 | Viewed by 158 | Submission Open

Keywords: diabetic retinopathy; natural antioxidants; oxidative stress; epigenetic mechanisms; biomarkers; diagnostic methods

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Statins as Antioxidants: Beyond Their Cholesterol Lowering Activity

edited by

Arianna Vignini

and Sonila Alia

submission deadline 31 Jul 2025 | Viewed by 150 | Submission Open

Keywords: statins; cholesterol; HMGCoA reductase; antioxidant; anti-inflammatory; dysmetabolic diseases

Peroxiredoxins

edited by

Dong-Seok Lee

submission deadline 31 Jul 2025 | Viewed by 121 | Submission Open

Keywords: peroxiredoxins; oxidative stress; neuron; neuroinflammation; stemness; cancer

(This special issue belongs to the Section Antioxidant Enzyme Systems)

Oxidative Stress and Inflammation in Heart Failure

edited by Camilla Hage

submission deadline 31 Jul 2025 | Viewed by 115 | Submission Open

Keywords: heart failure; oxidative stress; HFrEF; HFpEF; reactive oxygen species; nitric oxide; cardiomyocytes; cardiomyopathies; cardiac dysfunction

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Natural Antioxidants and Metabolic Diseases

edited by

José Ángel Rufián-Henares

Fortuna Iannuzzo

Maria Maisto

and

Elisabetta Schiano

submission deadline 20 Aug 2025 | 9 articles | Viewed by 20815 | Submission Open

Keywords: metabolic syndrome; antioxidant compounds; diabetes; obesity; cardiovascular diseases; biological effects; food sources; medicinal plants; oxidative stress; inflammation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Janus Face of Oxidative Stress in Normal and Pathological Conditions

edited by

Marco Fiore

submission deadline 20 Aug 2025 | 5 articles | Viewed by 5568 | Submission Open

Keywords: ethanol; toxicity; abuse; addiction; binge drinking; oxidative stress; psychoactive drug; cancer; recreational drug; FASD

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

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