Antioxidant Therapies in Cardiovascular, Cardiorenal and Metabolic Diseases

Dear Colleagues,

Oxidative stress is a condition which arises when there is an altered equilibrium between the reactive oxygen species (ROS) and the cellular defense system (antioxidant enzymes). The accumulation of ROS and the decline in the activity of antioxidant enzymes leads to increased oxidative stress. Such increased oxidative stress affects the physiological, biochemical, and molecular functions of the cell followed by the abnormal metabolism and functioning of the cell, tissue, organ, and organ system. Increased oxidative stress in cardiac and renal tissue affects the anatomy and physiology of the heart and kidney, respectively. Increased oxidative stress also induces the inflammation and triggers the malfunctioning of the autonomic nervous system. Both natural and synthetic compounds, by scavenging ROS and activating antioxidant enzymes, have shown a significant decline in oxidative stress and mitigating the life-threatening outcomes of ROS in the cardiovascular and renal system. Currently, nanotechnology-based antioxidant therapies are being examined as potential antioxidant therapies for the cardiovascular, cardiorenal, and metabolic diseases.

This Special Issue aims to collect original research articles, reviews, perspectives, and short communications related to the potential antioxidant therapeutic approaches for the treatment of cardiovascular, cardiorenal, and metabolic diseases. As Guest Editors, we invite you to submit your research or review manuscripts to this Special Issue, which will bring together all the current potential therapeutic strategies to reduce oxidative stress and prevent diseases associated with heart and kidney.

Prof. Dr. Kaushik P. Patel
Dr. Hong Zheng
Guest Editors

Dr. Tapan Patel
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.