Application of Next Generation Sequencing for Studying the Resistance of Environmental Pathogens
A special issue of Antibiotics (ISSN 2079-6382).
Deadline for manuscript submissions: 31 January 2025 | Viewed by 170
Special Issue Editors
Interests: microbiology; bioinformatics; metagenomics
Interests: biopathology; clinical microbiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
“Environmental pathogens” are organisms that normally spend a substantial part of their lifecycle outside human hosts. The world around us consists of a complex and dense network of microbes, including parasites, fungi, bacteria, and viruses. These microorganisms have either a direct impact on human health by causing diseases or an indirect effect as a vehicle for the transmission of antimicrobial determinants and virulence genes. Given that the majority of these microorganisms cannot be grown in the laboratory, only a tiny fraction of them have been characterized. So, there is an urgent need for new innovative approaches for studying environmental pathogens.
Next generation sequencing (NGS) offers the possibility to sequence microbial environmental genomes directly from samples (metagenome). The NGS data analyzed by bioinformatic tools enable the rapid and accurate characterization of the microbial composition and the detection of determinants conferring resistance to antimicrobial agents and genes encoding virulence factors. The introduction of NGS in “Environmental Ecology”, contributes to our understanding of the perpetuating disease mechanisms and to the limiting the threat posed by environmental pathogens.
In this Special Issue, “Application of Next Generation Sequencing for studying environmental pathogens”, we welcome reviews, original research, and short communications on new insights regarding the application of NGS in environmental samples.
Dr. Skoulakis Anargyros
Prof. Dr. Efthymia Petinaki
Guest Editors
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Keywords
- next generation sequencing
- metagenome
- environmental pathogens
- bioinformatics
- antimicrobial resistant determinants
- virulence factors
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