Special Issue "Feature Papers in Therapy of Diabetic Foot Infections"
Deadline for manuscript submissions: 31 December 2022 | Viewed by 336
Interests: prevention and treatment of orthopedic infections, including diabetic foot infections
2. Infectiology and Infection Control, Balgrist University Hospital, Zurich, Switzerland
Interests: diabetic foot infections; orthopedic infections
Diabetic foot infections (DFIs), soft tissue infections and osteomyelitis alike are multifaceted diseases. Usually, the infection is the tip of the iceberg of a larger, chronic, underlying problem. Hence, the management of all DFIs is multidisciplinary and includes the use of antibiotics, surgery, professional wound care and podiatry, adequate off-loading, re-vascularization, the patient's participation, glycemic control, and many other aspects such as the availability of nationwide policies, guidelines, or local financial and organizational resources. The burden that DFIs represent is high and is expected to rise in the future in virtually every region worldwide
Diabetic foot infections probably represent one of the largest fields of medicine with recurrent antibiotic overuse in relation to their moderate and short-term benefits. There are multiple reasons why therapy fails, ranging from the lack of compliance with off-loading, inadequate debridement, ischemia, the occurrence of a new infection, and the selection of new pathogens, to the recurrence of infection with the same pathogens as those present in a previous episode. However, only true recurrences of infection can definitively be prevented by the use of antibiotic treatment.
Although there is a rising number of scientific publications regarding antibiotic treatments for various subsets of DFI, questions remain: the use of oral versus intravenous versus local antibiotics; the optimal duration of systemic antibiotic therapy, the need for biofilm-acting agents; the costs and side effects of antibiotic use; the promotion of antibiotic resistance through from DFI treatments; as well as difficulties in terms of reimbursement and healthcare policies, which may vary from one country to the other and compromise the overall success of DFI management on a large scale.. Finally, antibiotic stewardship in the DFI population may also include non-antibiotic, diagnostic, and therapeutic measures. This Special Issue addresses these issues in line with antibiotic management in DFIs.
Prof. Dr. Ilker Uckay
Dr. Laura Soldevila
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- diabetic foot infection
- diabetic foot osteomyelitis
- systemic antibiotic therapy
- local antibiotic therapy
- side effects
- treatment success
- antibiotic stewardship
- antibiotic policies and difficulties