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Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Research on Immune Response and Vaccines: 2nd Edition

edited by James Galloway

submission deadline 30 Apr 2026 | 16 articles | Viewed by 74960 | Submission Open

Keywords: vaccines; immunogenicity; antigen recognition; adaptive immunity; cytokine response COVID-19; influenza; HPV; tuberculosis (BCG); malaria; HIV

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Varicella and Zoster Vaccination

edited by

Peter Maple

submission deadline 30 Apr 2026 | 14 articles | Viewed by 64079 | Submission Open

Keywords: varicella-zoster virus; chickenpox; shingles; vaccination; epidemiology; geographical regions; neurological diseases; SARS-CoV-2

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Human Papillomavirus Vaccine Against Cervical Cancer: New Usage Strategies and Coverage Issues

edited by

Luca Giannella

and

Andrea Ciavattini

submission deadline 30 Apr 2026 | 8 articles | Viewed by 43482 | Submission Open

Keywords: HPV vaccination coverage; HPV vaccination after conization; HPV vaccination in fertility-sparing treatment; male HPV vaccination HPV; vaccination after hysterectomy; tools for HPV vaccination implementation; HPV genotype in pre-invasive and invasive cervical pathology; HPV vaccination in vaginal pathology; HPV vaccination in vulvar pathology

(This special issue belongs to the Section Human Papillomavirus Vaccines)

COVID-19 Vaccination and Public Health: Addressing Global, Regional and Within-Country Inequalities

edited by

Dimitris Papamichail

and

Pietro Ferrara

submission deadline 30 Apr 2026 | 12 articles | Viewed by 32437 | Submission Open

Keywords: COVID-19 vaccine; population impact of COVID-19 vaccination; public health surveillance; health inequalities; access

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Novel Vaccine Designs to Enhance the Engagement of Innate and Adaptive Immunity

edited by

Martin H. Bluth

and

Fangfeng Yuan

submission deadline 30 Apr 2026 | 9 articles | Viewed by 16958 | Submission Open

Keywords: vaccine; innate immunity; adaptive immunity; infectious disease; novel strategy; antigen delivery; protein engineering; adjuvants

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Production of Plant-Based Vaccines and Therapeutics

edited by Laurence K. Grill, John Howard and Kelvin Phiri

submission deadline 30 Apr 2026 | 2 articles | Viewed by 16780 | Submission Open

Keywords: plant-produced; viral-vectored; therapeutics; vaccines; tobacco mosaic virus (TMV)

Personalised Cancer Vaccines

edited by Andrew L. Coveler

submission deadline 30 Apr 2026 | 4 articles | Viewed by 12369 | Submission Open

Keywords: peptide vaccines; mRNA vaccines; DNA vaccines; cancer vaccines

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Vaccines and Immunization: Measles, Mumps, and Rubella

edited by Nobuhiko Okabe

submission deadline 30 Apr 2026 | 4 articles | Viewed by 6543 | Submission Open

Keywords: measles; mumps; rubella; SSPE; hearing loss; CRS; immune mechanism; epidemiology; resurgence; life-course immunization

(This special issue belongs to the Section Epidemiology and Vaccination)

Advancing Health: Vaccination and Infectious Disease Prevention in Pregnant Women, Neonates, Infants, and Children

edited by

Eleni Vergadi

submission deadline 30 Apr 2026 | 2 articles | Viewed by 4453 | Submission Open

Keywords: infectious diseases; maternal immunization; pediatric infection control; immunization coverage; health equity; immunization strategies; vaccine safety

(This special issue belongs to the Section Vaccines and Public Health)

BCG Vaccine and Beyond: Innovations in Tuberculosis Vaccination and Inflammation-Related Disease Prevention

edited by

Xiao-Yong Fan

and

Zhi-Dong Hu

submission deadline 30 Apr 2026 | 3 articles | Viewed by 3863 | Submission Open

Keywords: tuberculosis; vaccine; vaccination; immune response; adjuvant; T-cell; immune memory; adaptive immunity; innate immune memory; correlates of protection

(This special issue belongs to the Section Vaccines against Infectious Diseases)

Arboviral Infections (Dengue, Chikungunya, Zika, and Other Mosquito-Borne Diseases): Immune Response and Vaccine Development

edited by

Bo Peng

and Xiaolu Shi

submission deadline 30 Apr 2026 | 3 articles | Viewed by 3594 | Submission Open

Keywords: arbovirus; dengue virus; chikungunya virus; Zika virus; mosquito-borne disease; immune response; cross-immunity; antibody-dependent enhancement (ADE); vaccine development; immunopathology

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Factors Influencing Vaccine Uptake and Immunization Outcomes

edited by Sitong Luo, Meiqi Xin and

Zixin Wang

submission deadline 30 Apr 2026 | 4 articles | Viewed by 2708 | Submission Open

Keywords: vaccination; vaccine uptake; immunization

(This special issue belongs to the Section Vaccines and Public Health)

Immune Responses in Patients with Chronic Disease After Vaccination

edited by

Nikola Stojanović

and

Marko Baralic

submission deadline 30 Apr 2026 | 1 articles | Viewed by 2165 | Submission Open

Keywords: immunity; vaccine; chronic kidney disease; glomerulonephritis; systemic lupus erythematosus; vasculitis; kidney transplant; schizophrenia; bipolar disorder; diabetes

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Antiviral Immunity and Vaccine Development

edited by

Caijun Sun

and Tao Yu

submission deadline 30 Apr 2026 | 1 articles | Viewed by 2080 | Submission Open

Keywords: antiviral innate immunity; adaptive immune responses; viral pathogenesis; immune evasion; host– virus interactions; antiviral vaccine development; vaccine design; novel vaccine platforms; vaccine adjuvants; vaccines and therapeutics

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

Recent Advances and Strategies for the Management of CIN and HPV Eradication Starategies for the Prevention of Uterine Cervical Cancer

edited by

Masaru Sakamoto

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1878 | Submission Open

Keywords: CIN; 9-valent HPV vaccine; HPV L2-VLP vaccine; HPV therapeutic vaccine; endocervical conization; laser vaporization; PDT

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Vaccines for Poultry Viruses

edited by

Dingxiang Liu

and Ying Liao

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1746 | Submission Open

Keywords: poultry viruses; vaccines; recombinant vaccines; vector-based vaccines; DNA/mRNA vaccines; vaccine delivery; adjuvants; vaccine efficacy

(This special issue belongs to the Section Veterinary Vaccines)

Influenza Vaccines and Influenza Vaccination in Europe

edited by George Kassianos

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1704 | Submission Open

Keywords: vaccines; vaccine design; influenza; vaccination rates; vaccine efficacy; effectiveness; vaccine safety; vaccine development; adjuvant; recombinant influenza vaccine; cell-based; egg-derived; mRNA; vaccination strategies; vaccine response; antivirals

(This special issue belongs to the Section Influenza Virus Vaccines)

State of the Art of Flavivirus Virus Research

edited by

Tomoyoshi Komiya

submission deadline 30 Apr 2026 | Viewed by 549 | Submission Open

Keywords: flavivirus; vaccine; infection control; diagnosis; epidemiology

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Immunological Responses to mRNA Vaccines

edited by Hyeri Seok

submission deadline 30 Apr 2026 | Viewed by 494 | Submission Open

Keywords: infectious; vaccine; immune response; immunogenicity; vaccine-induced immunity

Oral Vaccines: Challenges, Immunity and Therapeutic Advances

edited by Amin Safa

submission deadline 30 Apr 2026 | Viewed by 463 | Submission Open

Keywords: oral vaccines; mucosal immunity; Peyer’ s patches; nanoparticles; probiotic delivery; cancer immunotherapy; gastrointestinal barriers; antigen presentation

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

The Need for an HIV Vaccine in the Era of Highly Effective PrEP

edited by Michele Peake Andrasik, William O. Hahn and Susan P. Buchbinder

submission deadline 30 Apr 2026 | Viewed by 455 | Submission Open

Keywords: HIV; vaccines; HIV prevention; bnAbs; clinical trials

(This special issue belongs to the Section HIV Vaccines)

Genetically Engineered Mouse Models in Vaccine Development

edited by Deshan Ren and

Bingqian Qu

submission deadline 30 Apr 2026 | Viewed by 363 | Submission Open

Keywords: vaccine; immunogenicity; knockout; knockin; transgenic mice; humanized mice; xenografts; NCG/NKG/NRG/NSG; viruses

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Tumor Vaccines: Current Processes, Prevailing Challenges and Future Perspectives

edited by Xingxing He and Honglin Jin

submission deadline 1 May 2026 | 9 articles | Viewed by 45849 | Submission Open

Keywords: tumor vaccine; mRNA vaccine; personalized medicine; adjuvant; delivery strategies; cancer immunotherapy; personalized vaccines

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Exploring Cutaneous Autoimmune Disease Flares in the Wake of COVID-19 Infection and Vaccination

edited by Angeliki-Victoria Roussaki-Schulze, Efterpi Zafiriou and

Emmanouil Karampinis

submission deadline 10 May 2026 | Viewed by 615 | Submission Open

Keywords: COVID-19 infection; COVID-19 vaccination; psoriasis; inflammatory dermatoses; alopecia; bullous dermatoses; adverse reactions; exanthem

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Swine Vaccines and Vaccination

edited by

Fanzhi Kong

submission deadline 15 May 2026 | 4 articles | Viewed by 7618 | Submission Open

Keywords: swine fever; classical swine fever virus; african swine fever virus; live attenuated vaccines; subunit vaccines; nanopartical vaccines

(This special issue belongs to the Section Veterinary Vaccines)

Vaccination and Treatments Against Viral Hepatitis: Achievements, Challenges and Perspectives, 2nd Edition

edited by

Bárbara Vieira Do Lago

and

Vinicius M. Mello

submission deadline 20 May 2026 | Viewed by 392 | Submission Open

Keywords: vaccination; treatments; viral hepatitis; hepatitis A– E

(This special issue belongs to the Section Hepatitis Virus Vaccines)

Innovative Vaccines and Technologies to Address Tropical Parasitic Diseases

edited by

Cecilia Maria Perez Brandan

Iván Marcipar

and Fernando Sanchez-Valdez

submission deadline 30 May 2026 | Viewed by 346 | Submission Open

Keywords: tropical parasitic diseases; vaccine development; chimeric and multiepitope vaccines; immunomodulation and adjuvants; host– parasite interaction; biotechnology-based vaccine platforms

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Evaluation of Vaccine Efficacy, Safety and Immunogenicity Against Influenza, RSV and COVID-19

edited by

Roland Zahn

submission deadline 31 May 2026 | 11 articles | Viewed by 33421 | Submission Open

Keywords: influenza; respiratory syncytial virus (RSV); COVID-19; SARS-CoV-2; vaccines; immunogenicity; efficacy; safety; universal vaccine

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Vaccination, Public Health and Epidemiology

edited by

Ricardo Izurieta

submission deadline 31 May 2026 | 9 articles | Viewed by 28077 | Submission Open

Keywords: vaccine; vaccinology; epidemiology; infectious diseases; public health; emerging infectious diseases; tropical neglected diseases

(This special issue belongs to the Section Vaccines and Public Health)

Clinical Strategies to Improve Efficacy, Effectiveness, and Safety of Vaccination in Humans

edited by

Kay Choong See

submission deadline 31 May 2026 | 11 articles | Viewed by 25658 | Submission Open

Keywords: adenovirus vaccines; immunologic adjuvants; adult; communicable diseases; geriatrics; immunocompromised Host; mRNA vaccines; pediatrics; public health; attenuated vaccines; inactivated vaccines

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Safety and Immunogenicity of Vaccination

edited by Jennifer Serwanga

submission deadline 31 May 2026 | 7 articles | Viewed by 16167 | Submission Open

Keywords: vaccine safety; immunogenicity profiling; correlates of protection; vaccine-induced immunity; dose optimization and adjuvants; breakthrough infections; long-term immune memory; vaccines in special populations

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

A One-Health Perspective on Immunization Against Infectious Diseases

edited by Jose Camilla Sammartino

submission deadline 31 May 2026 | 6 articles | Viewed by 14001 | Submission Open

Keywords: One-Health vaccinology; immunization; vaccine; antibody; infectious disease; emerging pathogens; climate change; sustainability

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Vaccines to Achieve Affordable Universal Coverage

edited by Pui Hong Chung

submission deadline 31 May 2026 | 2 articles | Viewed by 9683 | Submission Open

Keywords: Sustainable Development Goals (SDGs); global health; vaccines; vaccine equity; vaccine disparities; vaccine accessibility; vaccination literacy; vaccine innovation; disease prevention; vaccine policy and implementation; public health policy; health economics; healthcare disparities; universal health coverage; international health partnerships

(This special issue belongs to the Section Vaccines and Public Health)

Research on HIV/AIDS Vaccine

edited by Portia Chipo Mutevedzi and

Nagesh Kolishetti

submission deadline 31 May 2026 | 3 articles | Viewed by 9550 | Submission Open

Keywords: HIV; antiretroviral treatment (ART); vaccines; drug resistance; vaccine efficacy

(This special issue belongs to the Section HIV Vaccines)

Population Immunity and Persistence to SARS-CoV-2 Induced by Infection and Vaccination, Protection Against New Infections and Implication for Further Vaccination: 2nd Edition

edited by Juan Yang and Wei Wang

submission deadline 31 May 2026 | 3 articles | Viewed by 5907 | Submission Open

Keywords: SARS-CoV-2; COVID-19; serology; population immunity; hybrid immunity; vaccination; antibody kinetics; cross-protection

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Animal Infectious Diseases and Vaccinology in One Health

edited by

Edith Rojas-Anaya

and Elizabeth Loza-Rubio

submission deadline 31 May 2026 | 2 articles | Viewed by 4535 | Submission Open

Keywords: vaccinology; productive animals; one health; infectious diseases; zoonoses

(This special issue belongs to the Section Veterinary Vaccines)

Vaccine, Preventive Strategies and Antiviral Responses to Zoonotic Viruses

edited by

Wei Ye

, Shu Shen, Chen Peng and Ben Hu

submission deadline 31 May 2026 | 1 articles | Viewed by 3588 | Submission Open

Keywords: alphavirus; arenavirus; bunyavirus; coronavirus; flavivirus; filovirus; orthomyxovirus (e.g.; avian influenza virus); orthopoxvirus; paramyxovirus; rhabdovirus

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Innovative Vaccines That Modulate the Immune System to Enhance Cancer Therapy

edited by

Ruchi Roy

submission deadline 31 May 2026 | 1 articles | Viewed by 3026 | Submission Open

Keywords: cancer vaccines; CAR T cell therapy; checkpoint-inhibitors; combination therapy; tumor microenvironment; tumor-infiltrating lymphocytes

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Advances in Pneumococcal Vaccines: Efficacy, Implementation, and Coverage

edited by Jose María Marimón

submission deadline 31 May 2026 | 2 articles | Viewed by 2444 | Submission Open

Keywords: pneumococcal conjugate vaccines; pneumococcal diseases; streptococcus pneumoniae serotypes; serotype replacement

Advances in the Use of Nanoparticles for Vaccine Platform Development: 2nd Edition

edited by

Imran Saleem

submission deadline 31 May 2026 | 1 articles | Viewed by 2370 | Submission Open

Keywords: nanoparticles; vaccine; immunotherapy; subunit vaccine; RNA vaccine; adjuvant; nanotechnology

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Factors Affecting and Strategies Enhancing the Willingness to Receive and Uptake of Seasonal Influenza Vaccination

edited by

Paul Shing-fong Chan

submission deadline 31 May 2026 | 2 articles | Viewed by 2178 | Submission Open

Keywords: factors; strategies; willingness; uptake; seasonal influenza vaccination

(This special issue belongs to the Section Vaccines and Public Health)

Advances in Immunotherapy of Cancer

edited by Li Ye and Jiajun Fan

submission deadline 31 May 2026 | 1 articles | Viewed by 1997 | Submission Open

Keywords: cancer vaccines; neoantigen; immunotherapy; cancer microenviroment

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Recent Research on Adenovirus-Vectored Vaccines

edited by

Michael A. Barry

and

Vijay S. Reddy

submission deadline 31 May 2026 | 1 articles | Viewed by 1505 | Submission Open

Keywords: adenovirus; replication competent; single cycle; replication defective; serotypes; targeting; structure; cryo-EM; vaccines

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

SARS-CoV-2 Pathogenesis, Vaccines and Therapeutics

edited by

Hatem A. Elshabrawy

submission deadline 31 May 2026 | 1 articles | Viewed by 1188 | Submission Open

Keywords: vaccine; SARS-CoV-2; COVID-19; antibodies; antivirals

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Therapeutic Cancer Vaccines: Advances, Challenges, and Future Directions

edited by Erminia Massarelli and Victoria M. Villaflor

submission deadline 31 May 2026 | 1 articles | Viewed by 787 | Submission Open

Keywords: therapeutic cancer vaccines; clinical trials; solid tumors; malignant hematology; peptide vaccines; DNA vaccines; vector vaccines; dendritic cell vaccines; allogenic vaccines; mRNA vaccines

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Vaccines Based on Dendritic Cells: Breaking Barriers to New Immune Response Approach

edited by

Soledad Lopez-Enriquez

submission deadline 31 May 2026 | Viewed by 546 | Submission Open

Keywords: plasmacytoid dendritic cells; myeloid dendritic cells; immunotolerance; regulatory T cells; cytotoxic T cells; NK cells; immunotherapies; nanovaccines; immunometabolism; delivery systems

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Advances in Serologic Assays for Vaccination Monitoring and Assessment of Immune Protection

edited by Paul D. Olivo and Randolph F.R. Rasch

submission deadline 31 May 2026 | Viewed by 490 | Submission Open

Keywords: vaccines; vaccine-preventable diseases; antibodies; serology; correlates of protection; biomarkers of immunity; immunosurveillance

(This special issue belongs to the Section Epidemiology and Vaccination)

Avian Viruses and the Host Immune System

edited by

Kang Ning

, Junfeng Lv and

Xiujuan Zhang

submission deadline 31 May 2026 | Viewed by 422 | Submission Open

Keywords: avian; waterfowl; viral diseases; vaccination strategies; viral vector development; host immune response

(This special issue belongs to the Section Veterinary Vaccines)

NK Cell-Mediated Immune Responses and Tumor Defense

edited by

Dae Joong Kim

and Luc Van Kaer

submission deadline 31 May 2026 | Viewed by 377 | Submission Open

Keywords: innate immunity; metastasis; MHC class I; immunotherapy; cytokines; STING; IFNγ ; NK cell engager; CD8 T cell; chimeric antigen receptors (CARs)

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Virus-Like Particle (VLP) Vaccines Against Emerging Infectious Diseases—2nd Edition

edited by

Gang Ye

submission deadline 31 May 2026 | Viewed by 377 | Submission Open

Keywords: emerging infectious diseases (EIDs); virus-like particle (VLP); vaccines

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

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