BCG Vaccine and Beyond: Innovations in Tuberculosis Vaccination and Inflammation-Related Disease Prevention
A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Vaccines against Infectious Diseases".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 79
Special Issue Editors
Interests: Mycobacterium tuberculosis; BCG; vaccine; infection and immunity; tuberculosis; diagnosis; trained immunity; immunotherapy
Special Issue Information
Dear Colleagues,
Tuberculosis (TB) remains one of the deadliest infectious diseases globally, claiming over 1.3 million lives annually despite decades of research and public health efforts. The Bacillus Calmette–Guérin (BCG) vaccine, developed a century ago, provides partial protection against severe forms of childhood TB, but has limited efficacy in preventing pulmonary TB in adolescents and adults. There is an urgent need to accelerate the development and deployment of next-generation TB vaccines. Recent advances in immunology, genomics, and vaccine delivery systems have reignited hope for achieving the WHO’s End TB Strategy targets. This Special Issue seeks to consolidate cutting-edge research and foster interdisciplinary collaboration to address critical gaps in TB vaccine science and implementation. We are pleased to invite you to contribute to this Special Issue focused on “Tuberculosis Vaccines and Vaccination”.
This Special Issue aims to gather articles presenting state-of-the-art research, novel discoveries, and the latest progress of novel tuberculosis vaccines and vaccination in pre-clinical and clinical studies.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:
- Novel approaches to improve the protective efficacy of current TB vaccines;
- Novel vaccine delivery methods;
- Novel insights and approaches to TB vaccine development in pre-clinical and clinical studies;
- Immune correlates of protection studies in tuberculosis vaccine research;
- The role of vaccine-induced innate immune memory in tuberculosis vaccines;
- The role of tissue-resident memory cells in tuberculosis vaccines.
We look forward to receiving your contributions.
Prof. Dr. Xiao-Yong Fan
Prof. Dr. Zhi-Dong Hu
Guest Editors
Manuscript Submission Information
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Keywords
- tuberculosis
- vaccine
- vaccination
- immune response
- adjuvant
- T-cell
- immune memory
- adaptive immunity
- innate immune memory
- correlates of protection
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