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Biology, Volume 9, Issue 4

April 2020 - 26 articles

Cover Story: Before we can answer questions on the origins of morphological and ecological diversity, we need a solid understanding of the phylogenetic relationships of the species of interest. Ideally, this phylogeny is backed by sufficient amounts of data and represents the diversity of the group. In this Issue, authors investigated the phylogenetic relationships of Terebelliformia, a group of mostly marine segmented worms (Annelida) that includes spaghetti worms, Pompeii worms, ice cream cone worms, and their relatives. A dataset of thousands of genetic loci sequenced for the main lineages of the group formed a well-supported backbone, which guided the analysis of smaller but taxonomically more representative datasets for 121 species. This approach provided a robust understanding into the relationships among different lineages and into the evolution of their remarkable morphological diversity. View this paper.
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Articles (26)

  • Article
  • Open Access
3 Citations
3,252 Views
11 Pages

24 April 2020

(1) Background: Direct-acting antiviral therapy for chronic hepatitis C virus (HCV) infection is associated with high sustained virologic response (SVR) and overcomes negative predictive factors, including steatosis, in patients without human immunod...

  • Feature Paper
  • Article
  • Open Access
25 Citations
4,466 Views
17 Pages

Structural and Functional Peculiarities of α-Crystallin

  • Olga M. Selivanova and
  • Oxana V. Galzitskaya

23 April 2020

α-Crystallin is the major protein of the eye lens and a member of the family of small heat-shock proteins. Its concentration in the human eye lens is extremely high (about 450 mg/mL). Three-dimensional structure of native α-crystallin is...

  • Review
  • Open Access
26 Citations
8,105 Views
13 Pages

23 April 2020

Parkinson’s disease (PD) is the most common neurodegenerative movement disorder without any objective biomarker available to date. Increasing evidence highlights the critical role of neuroinflammation, including T cell responses, and spreading...

  • Article
  • Open Access
4 Citations
4,839 Views
8 Pages

Clinical Effectiveness of a Combination of Black Elder Berries, Violet Herb, and Calendula Flowers in Chronic Obstructive Pulmonary Disease: The Results of a Double-Blinded Placebo-Controlled Study

  • Tatiana V. Kirichenko,
  • Igor A. Sobenin,
  • Yuliya V. Markina,
  • Elena V. Gerasimova,
  • Andrey V. Grechko,
  • Dmitry A. Kashirskikh,
  • Elena B. Romanenko,
  • Wei-Kai Wu and
  • Alexander N. Orekhov

22 April 2020

Chronic obstructive pulmonary disease (COPD) is a multifactorial disease, in which systemic inflammation plays a key role. This 6-month randomized double-blinded placebo-controlled study evaluates the possible effect of natural preparation Inflaminat...

  • Article
  • Open Access
10 Citations
3,129 Views
9 Pages

The Impact of Insurance and Marital Status on Survival in Patients with Nasopharyngeal Carcinoma

  • Chih-Chun Wang,
  • Ching-Chieh Yang,
  • Shyh-An Yeh,
  • Chung-I Huang,
  • Tzer-Zen Hwang,
  • Chuan-Chien Yang and
  • Yu-Chieh Su

22 April 2020

Objective: This study aimed to explore the influence of social support on the survival outcomes of patients with nasopharyngeal carcinoma (NPC). We examined whether the combined proxy influenced whether patients were more likely to receive radiothera...

  • Article
  • Open Access
6 Citations
4,817 Views
17 Pages

Overexpression of T-bet, GATA-3 and TGF-ß Induces IFN-γ, IL-4/13A, and IL-17A Expression in Atlantic Salmon

  • Tiril H. Slettjord,
  • Hege J. Sekkenes,
  • Heng Chi,
  • Jarl Bøgwald,
  • Trilochan Swain,
  • Roy A. Dalmo and
  • Jaya Kumari Swain

20 April 2020

The overexpression of GATA-3, T-bet and TGF-ß may theoretically induce IL-4/A, IFN-γ and IL-17A expression, respectively. Whether this also applies to fish is not yet known. The plasmid vectors encoding reporter gene (RFP)-tagged T-bet, G...

  • Review
  • Open Access
14 Citations
6,214 Views
13 Pages

20 April 2020

Extracorporeal circulation (ECC) methods are being increasingly used for mechanical support of respiratory and cardio-circulatory failure. Especially, cardiopulmonary bypass (CPB) during cardiovascular surgery, sustenance of the patient’s life...

  • Review
  • Open Access
70 Citations
5,423 Views
21 Pages

Matrix Metalloproteases in Pancreatic Ductal Adenocarcinoma: Key Drivers of Disease Progression?

  • Etienne J. Slapak,
  • JanWillem Duitman,
  • Cansu Tekin,
  • Maarten F. Bijlsma and
  • C. Arnold Spek

18 April 2020

Pancreatic cancer is a dismal disorder that is histologically characterized by a dense fibrotic stroma around the tumor cells. As the extracellular matrix comprises the bulk of the stroma, matrix degrading proteases may play an important role in panc...

  • Concept Paper
  • Open Access
3 Citations
3,657 Views
11 Pages

17 April 2020

Cancer recurrence has remained a significant challenge, despite advances in therapeutic approaches. In part, this is due to our incomplete understanding of the biology of cancer stem cells and the underlying molecular mechanisms. The phenomenon of di...

  • Article
  • Open Access
12 Citations
5,290 Views
27 Pages

Molecular Identification and Evaluation of the Genetic Diversity of Dendrobium Species Collected in Southern Vietnam

  • Nhu-Hoa Nguyen,
  • Huyen-Trang Vu,
  • Ngoc-Diep Le,
  • Thanh-Diem Nguyen,
  • Hoa-Xo Duong and
  • Hoang-Dung Tran

10 April 2020

Dendrobium has been widely used not only as ornamental plants but also as food and medicines. The identification and evaluation of the genetic diversity of Dendrobium species support the conservation of genetic resources of endemic Dendrobium species...

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Biology - ISSN 2079-7737Creative Common CC BY license